Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6W5P4

Entry ID Method Resolution Chain Position Source
AF-Q6W5P4-F1 Predicted AlphaFoldDB

345 variants for Q6W5P4

Variant ID(s) Position Change Description Diseaes Association Provenance
RCV000002276
CA115395
rs324981
VAR_023757
107 N>I Asthma-related traits, susceptibility to, 2 increases cell surface expression and NPS-dependent calcium mobilization; does not affect affinity for NPS. [ClinVar, UniProt] Yes ClinGen
ClinVar
UniProt
1000Genomes
ESP
ExAC
TOPMed
dbSNP
gnomAD
CA367261449
rs1424178803
2 P>S No ClinGen
gnomAD
rs1363464526
CA367261462
3 A>D No ClinGen
gnomAD
rs766121315
CA4215635
3 A>T Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
TOPMed
gnomAD
rs753231326
CA4215636
5 F>L No ClinGen
ExAC
TOPMed
gnomAD
rs754542933
CA4215637
7 E>* No ClinGen
ExAC
TOPMed
gnomAD
rs75375241
CA156859692
7 E>D No ClinGen
Ensembl
rs754542933
CA156859691
COSM1698535
COSM1698536
7 E>K Variant assessed as Somatic; 0.0 impact. skin [NCI-TCGA, Cosmic] No ClinGen
cosmic curated
ExAC
NCI-TCGA
TOPMed
gnomAD
rs778384516
CA4215638
9 S>T No ClinGen
ExAC
gnomAD
CA4215640
rs375686103
11 D>G No ClinGen
ESP
ExAC
TOPMed
gnomAD
COSM36651
CA156859694
rs267601495
11 D>H skin [Cosmic] No ClinGen
cosmic curated
TOPMed
CA156859693
rs267601495
11 D>N Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
NCI-TCGA
TOPMed
TCGA novel 12 S>F Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA156859695
rs781670018
13 S>I No ClinGen
ExAC
TOPMed
gnomAD
CA4215641
rs781670018
13 S>N No ClinGen
ExAC
TOPMed
gnomAD
CA367261599
rs1385480995
14 G>W No ClinGen
gnomAD
rs1351919281
COSM3698381
COSM3698380
COSM3698382
COSM3698379
CA367261611
16 G>E Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] No ClinGen
cosmic curated
NCI-TCGA
gnomAD
CA367261609
rs769897360
CA4215643
16 G>R No ClinGen
ExAC
gnomAD
CA4215644
rs775791206
17 Q>E No ClinGen
ExAC
TOPMed
gnomAD
CA367261624
rs149663215
18 T>K No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA4215645
rs149663215
18 T>M Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
1000Genomes
ESP
ExAC
NCI-TCGA
TOPMed
gnomAD
CA4215647
rs115057146
19 L>P No ClinGen
1000Genomes
ExAC
gnomAD
CA4215648
rs761714609
22 S>F Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
rs1236178930
CA367261649
23 P>S No ClinGen
gnomAD
CA4215649
rs148428496
24 V>M No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs772877468
CA4215650
25 A>V No ClinGen
ExAC
gnomAD
CA4215652
rs765881654
26 C>F No ClinGen
ExAC
gnomAD
CA367261673
rs1173975745
27 T>A No ClinGen
TOPMed
gnomAD
rs753560177
CA4215653
28 E>A No ClinGen
ExAC
gnomAD
COSM107663
COSM107664
rs145130538
CA156859697
28 E>K skin [Cosmic] No ClinGen
cosmic curated
Ensembl
TCGA novel 29 T>A Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
TCGA novel 31 T>S Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1454882853
CA367261734
36 V>A No ClinGen
TOPMed
CA367261730
rs1246238293
36 V>M No ClinGen
Ensembl
rs757839925
CA4215657
37 E>A No ClinGen
ExAC
gnomAD
rs757839925
CA156859698
37 E>G No ClinGen
ExAC
gnomAD
rs781753839
CA4215658
38 G>V No ClinGen
ExAC
gnomAD
CA4215659
rs201430808
40 E>* No ClinGen
ESP
ExAC
TOPMed
gnomAD
TCGA novel 40 E>D Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA4215660
rs201430808
40 E>Q No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1480538286
CA367261765
41 W>* No ClinGen
TOPMed
CA367261773
rs1312232263
42 G>D No ClinGen
gnomAD
rs267601496
CA156859700
43 S>F Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
Ensembl
NCI-TCGA
CA156859699
rs999562532
43 S>P No ClinGen
Ensembl
rs1562631240
CA367261789
45 Y>H No ClinGen
Ensembl
TCGA novel 46 Y>* Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs116240309
CA156859701
47 S>F No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs1260501119
COSM746062
CA367261805
COSM746061
47 S>P lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] No ClinGen
cosmic curated
NCI-TCGA
gnomAD
CA4215662
rs116240309
47 S>Y No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA367260062
rs1349643308
51 E>D No ClinGen
gnomAD
rs1284529581
CA367260057
51 E>Q No ClinGen
gnomAD
COSM220240
COSM220239
CA4215692
rs543760020
53 L>F haematopoietic_and_lymphoid_tissue [Cosmic] No ClinGen
cosmic curated
1000Genomes
ExAC
gnomAD
rs775283041
CA4215693
54 I>V No ClinGen
ExAC
gnomAD
rs762509036
CA4215694
55 T>I Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
CA367260123
rs1256090452
61 V>I Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
NCI-TCGA
gnomAD
rs763680325
CA4215695
62 F>L No ClinGen
ExAC
CA156862515
rs751710810
62 F>S No ClinGen
Ensembl
rs751076118
CA4215696
63 T>A No ClinGen
ExAC
gnomAD
rs755050843
CA4215697
63 T>I No ClinGen
ExAC
TOPMed
gnomAD
CA4215698
rs563652943
64 I>V No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
CA4215700
rs755348662
66 G>E Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
rs116766176
CA4215699
66 G>R No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA156862517
rs752940003
68 S>A No ClinGen
ExAC
TOPMed
gnomAD
CA4215702
rs752940003
68 S>P No ClinGen
ExAC
TOPMed
gnomAD
rs777879974
CA4215704
69 V>A No ClinGen
ExAC
TOPMed
gnomAD
rs75764081
CA4215703
69 V>I No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs1444302806
CA367260173
70 V>L No ClinGen
gnomAD
rs781296883
CA4215707
CA4215708
75 W>R No ClinGen
ExAC
gnomAD
CA367260216
rs1255451409
76 R>S No ClinGen
gnomAD
CA4215710
rs769738896
79 K>E No ClinGen
ExAC
gnomAD
rs369040738
CA156862518
80 K>* No ClinGen
ESP
TOPMed
CA4215711
rs373297591
80 K>N No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs752444500 80 K>missing Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No NCI-TCGA
CA367260245
rs1457600695
81 S>A No ClinGen
gnomAD
rs748946517
CA4215712
83 M>T No ClinGen
ExAC
gnomAD
CA156862519
rs1038828004
84 T>A No ClinGen
Ensembl
rs1214003528
CA367260285
86 F>L No ClinGen
gnomAD
CA156862520
rs549686131
86 F>S No ClinGen
TOPMed
gnomAD
CA4215714
rs768230329
87 V>A No ClinGen
ExAC
gnomAD
rs1375476651
CA367260309
90 L>R No ClinGen
gnomAD
CA367260312
rs1467120948
91 A>S No ClinGen
TOPMed
gnomAD
CA4215715
rs773906121
93 T>I No ClinGen
ExAC
gnomAD
rs761286205
CA4215716
94 D>N No ClinGen
ExAC
TCGA novel 94 D>Y Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs565312186
CA4215741
95 S>Y Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
rs1562720134
CA367260377
97 T>I No ClinGen
Ensembl
rs751765167
CA4215742
98 G>* No ClinGen
ExAC
TOPMed
gnomAD
TCGA novel 101 N>D Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA367260401
rs1432152237
101 N>I No ClinGen
gnomAD
rs933869553
CA157265144
102 I>M No ClinGen
TOPMed
gnomAD
CA157265138
rs542257541
102 I>T No ClinGen
gnomAD
rs186967908
CA4215745
105 D>G No ClinGen
1000Genomes
ExAC
gnomAD
rs960721012
CA157265196
105 D>N No ClinGen
TOPMed
CA4215747
rs756113542
106 I>T No ClinGen
ExAC
TOPMed
CA4215748
rs780196686
107 N>D No ClinGen
ExAC
gnomAD
rs324981
CA367260439
107 N>S No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA4215750
rs763039204
109 R>* No ClinGen
ExAC
TOPMed
gnomAD
rs568145224
CA4215751
109 R>Q Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
1000Genomes
ExAC
NCI-TCGA
TOPMed
gnomAD
rs371040180
CA4215753
112 G>E No ClinGen
ESP
ExAC
TOPMed
CA367260468
rs1359443213
112 G>R No ClinGen
gnomAD
rs1301586831
CA367260474
113 D>H No ClinGen
gnomAD
CA4215755
rs375440531
115 T>M No ClinGen
ESP
ExAC
gnomAD
CA4215757
rs763341129
117 P>R No ClinGen
ExAC
gnomAD
rs1449032125
CA367260508
118 D>E No ClinGen
TOPMed
CA4215760
rs762092370
118 D>G No ClinGen
ExAC
gnomAD
CA4215759
rs368718436
118 D>H No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA4215758
rs368718436
118 D>N No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs1332310760
CA367260517
120 V>A No ClinGen
TOPMed
rs750515951
CA157265302
120 V>I No ClinGen
ExAC
TOPMed
gnomAD
rs750515951
CA4215762
120 V>L No ClinGen
ExAC
TOPMed
gnomAD
rs202169485
CA4215763
122 R>* Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
COSM224936
rs35436513
VAR_025103
COSM224937
CA4215764
122 R>Q Variant assessed as Somatic; 0.0 impact. skin [NCI-TCGA, Cosmic] No ClinGen
cosmic curated
UniProt
1000Genomes
ESP
ExAC
NCI-TCGA
TOPMed
dbSNP
gnomAD
CA4215765
rs753750194
123 V>E No ClinGen
ExAC
gnomAD
rs778542621
CA4215767
125 R>C No ClinGen
ExAC
TOPMed
gnomAD
COSM1217747
COSM1217748
CA4215768
rs373742826
125 R>H large_intestine [Cosmic] No ClinGen
cosmic curated
ESP
ExAC
TOPMed
gnomAD
rs368017225
CA4215770
126 Y>N No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs542000666
CA157265355
126 Y>S No ClinGen
1000Genomes
rs555318830
CA4215771
127 L>S No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs78508704
CA157269003
129 V>F No ClinGen
TOPMed
gnomAD
rs78508704
CA367259844
129 V>I No ClinGen
TOPMed
gnomAD
CA367259852
rs1193657013
130 V>E No ClinGen
gnomAD
COSM453002
rs376640561
COSM453003
CA4215793
132 L>F Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] No ClinGen
cosmic curated
ESP
ExAC
NCI-TCGA
TOPMed
gnomAD
rs114775765
CA4215796
134 A>T Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
1000Genomes
ExAC
NCI-TCGA
TOPMed
gnomAD
CA4215797
rs747202773
135 S>F No ClinGen
ExAC
gnomAD
rs372990147
CA367259895
137 Y>* No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA367259893
rs1365723924
137 Y>C No ClinGen
gnomAD
COSM3778413
CA4215799
rs376690361
COSM3778412
COSM3778414
138 V>I urinary_tract [Cosmic] No ClinGen
cosmic curated
ESP
ExAC
TOPMed
gnomAD
CA4215800
rs759677549
141 S>C No ClinGen
ExAC
TOPMed
gnomAD
rs325465
CA367259925
143 S>C No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs325465
RCV000948764
CA4215801
VAR_025104
143 S>G No ClinGen
ClinVar
UniProt
1000Genomes
ESP
ExAC
TOPMed
dbSNP
gnomAD
rs325465
CA367259924
143 S>R No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA367259936
rs1448314326
144 I>T No ClinGen
TOPMed
CA367259933
rs1186312421
144 I>V No ClinGen
TOPMed
CA4215802
rs775440956
145 D>E No ClinGen
ExAC
gnomAD
CA367259938
rs1174888031
145 D>H No ClinGen
TOPMed
gnomAD
rs143746221
CA4215803
146 R>S No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1360260807
CA367259957
147 Y>* No ClinGen
gnomAD
CA4215804
rs763858785
149 A>P No ClinGen
ExAC
gnomAD
CA367259976
rs1193378029
150 I>N No ClinGen
Ensembl
rs756851967
CA4215806
151 V>I No ClinGen
ExAC
TOPMed
gnomAD
CA157269086
rs756751266
153 P>R No ClinGen
Ensembl
rs767254511
CA4215807
153 P>S No ClinGen
ExAC
TOPMed
gnomAD
rs1438011853
CA367260000
154 M>T No ClinGen
gnomAD
rs1028773844
CA157269090
155 K>N No ClinGen
Ensembl
CA367260009
rs1227996795
155 K>R No ClinGen
TOPMed
rs755652890
CA4215809
157 L>I No ClinGen
ExAC
TOPMed
gnomAD
rs868156143
CA157269101
158 Q>* Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
Ensembl
NCI-TCGA
rs1343460838
CA367260704
160 E>G No ClinGen
gnomAD
CA4215810
rs200993440
160 E>K No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs200993440
CA157269119
160 E>Q No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA367260710
rs1225773634
161 K>E No ClinGen
gnomAD
CA367260718
rs1350421370
162 Q>* No ClinGen
TOPMed
TCGA novel 162 Q>K Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA4215837
rs780099659
163 A>G No ClinGen
ExAC
TOPMed
gnomAD
CA4215839
rs569538789
164 R>K No ClinGen
1000Genomes
ExAC
gnomAD
rs200741263
CA4215840
164 R>S No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA4215838
rs569538789
164 R>T No ClinGen
1000Genomes
ExAC
gnomAD
rs1017640284
CA157279326
165 V>F No ClinGen
Ensembl
CA4215841
rs761476084
166 L>F No ClinGen
ExAC
gnomAD
rs377097496
CA4215842
167 I>T No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA367260753
rs1266746861
168 V>A No ClinGen
gnomAD
CA4215843
rs772930017
169 I>N No ClinGen
ExAC
TOPMed
gnomAD
CA367260759
rs772930017
169 I>T No ClinGen
ExAC
TOPMed
gnomAD
rs766192701
CA367260762
170 A>S No ClinGen
ExAC
TOPMed
gnomAD
COSM283351
CA4215845
COSM283350
COSM3663167
rs766192701
170 A>T Variant assessed as Somatic; 0.0 impact. liver large_intestine [NCI-TCGA, Cosmic] No ClinGen
cosmic curated
ExAC
NCI-TCGA
TOPMed
gnomAD
TCGA novel 170 A>V Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1219928028
CA367260778
172 S>N No ClinGen
TOPMed
rs753340586
CA4215846
172 S>R No ClinGen
ExAC
TOPMed
gnomAD
TCGA novel 173 L>M Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA4215848
rs764654607
175 F>C No ClinGen
ExAC
TOPMed
gnomAD
rs1562759007
CA367260814
178 S>P No ClinGen
Ensembl
CA367260823
rs1562759014
179 I>T No ClinGen
Ensembl
CA367260820
rs1286017717
179 I>V No ClinGen
TOPMed
CA367260835
rs757750551
181 T>I No ClinGen
ExAC
TOPMed
gnomAD
CA4215850
rs757750551
181 T>N No ClinGen
ExAC
TOPMed
gnomAD
rs1225904473
CA367260851
184 I>V No ClinGen
gnomAD
CA367260857
rs1284415024
185 F>L No ClinGen
TOPMed
gnomAD
rs1295232920
CA367260864
186 G>R No ClinGen
TOPMed
rs749301919
CA367260900
191 S>C No ClinGen
ExAC
TOPMed
gnomAD
rs749301919
CA4215856
191 S>F Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
TOPMed
gnomAD
CA367260906
rs1159685581
192 N>S No ClinGen
TOPMed
rs778667665
CA4215858
193 G>S No ClinGen
ExAC
TOPMed
gnomAD
rs748097151
CA4215859
194 E>K No ClinGen
ExAC
TOPMed
gnomAD
CA367260923
rs1433852698
195 V>L No ClinGen
TOPMed
CA4215860
rs34705969
VAR_025105
197 C>F No ClinGen
UniProt
1000Genomes
ESP
ExAC
TOPMed
dbSNP
gnomAD
CA367260939
rs34705969
197 C>S No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA4215861
rs114485438
197 C>W No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
TCGA novel 198 W>C Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs552751963
CA367260956
200 L>M No ClinGen
1000Genomes
ExAC
gnomAD
CA367260959
rs1172236826
200 L>P No ClinGen
gnomAD
rs776453644
CA4215864
201 W>* No ClinGen
ExAC
gnomAD
CA4215865
rs759065076
202 P>S No ClinGen
ExAC
gnomAD
rs150717138
CA4215867
203 D>E Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ESP
ExAC
NCI-TCGA
TOPMed
gnomAD
rs375118842
CA157279409
204 D>H No ClinGen
ESP
TOPMed
gnomAD
CA157279405
rs375118842
204 D>N Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ESP
NCI-TCGA
TOPMed
gnomAD
CA4215868
rs762372799
206 Y>* No ClinGen
ExAC
gnomAD
CA367260994
COSM3832709
COSM3832711
COSM3832710
rs1406844918
206 Y>H Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] No ClinGen
cosmic curated
NCI-TCGA
gnomAD
CA157279413
rs368352815
209 P>A No ClinGen
ESP
rs767970790
CA4215869
210 Y>H No ClinGen
ExAC
gnomAD
rs750745749
CA4215870
211 M>T No ClinGen
ExAC
gnomAD
rs866505058
CA157279418
211 M>V No ClinGen
gnomAD
CA367261036
rs1327342373
212 T>A No ClinGen
gnomAD
rs35537374
CA4215871
VAR_025106
212 T>I No ClinGen
UniProt
1000Genomes
ESP
ExAC
TOPMed
dbSNP
gnomAD
rs754083738
CA4215874
214 V>L No ClinGen
ExAC
TOPMed
gnomAD
rs754083738
CA4215873
214 V>M No ClinGen
ExAC
TOPMed
gnomAD
rs1222565059
CA367261055
215 A>V No ClinGen
gnomAD
CA4215876
rs17170011
216 F>L No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA4215879
rs746759160
218 V>A No ClinGen
ExAC
TOPMed
gnomAD
rs1452290032
CA367261113
225 I>V No ClinGen
gnomAD
rs775056642
CA4215885
226 I>L No ClinGen
ExAC
TOPMed
gnomAD
rs775056642
CA4215884
226 I>V No ClinGen
ExAC
TOPMed
gnomAD
CA157283012
rs892058138
228 I>V No ClinGen
Ensembl
rs775960737
CA4215938
229 M>I No ClinGen
ExAC
TOPMed
gnomAD
rs916706976
CA157283014
229 M>V No ClinGen
TOPMed
gnomAD
CA4215939
rs763079218
232 I>T No ClinGen
ExAC
gnomAD
CA4215941
rs751628759
235 R>* Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
COSM171609
rs116249859
COSM171608
CA4215942
235 R>Q large_intestine [Cosmic] No ClinGen
cosmic curated
1000Genomes
ExAC
TOPMed
gnomAD
CA4215944
rs767525853
241 S>N No ClinGen
ExAC
gnomAD
rs727162
VAR_023758
CA4215945
241 S>R No ClinGen
UniProt
1000Genomes
ESP
ExAC
TOPMed
dbSNP
gnomAD
rs1409654873
CA367261249
243 T>N No ClinGen
TOPMed
CA367261257
rs199565777
244 Y>* No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA367261263
rs1403041686
245 E>A No ClinGen
gnomAD
CA4215948
rs140146458
245 E>K Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ESP
ExAC
NCI-TCGA
TOPMed
gnomAD
CA157283047
rs1001718461
246 T>I No ClinGen
Ensembl
TCGA novel 246 T>P Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA4215949
rs754573421
247 V>M No ClinGen
ExAC
gnomAD
rs778550553
CA4215950
250 N>S No ClinGen
ExAC
gnomAD
rs1217772905
CA367261300
251 C>S No ClinGen
TOPMed
gnomAD
rs747616486
CA367261308
252 S>* No ClinGen
ExAC
gnomAD
rs747616486
CA4215951
252 S>L No ClinGen
ExAC
gnomAD
rs907276853
CA157286009
253 D>G No ClinGen
TOPMed
CA4215974
rs373170949
258 S>N No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs927577850
CA157286015
258 S>R No ClinGen
Ensembl
CA367261362
rs1365615076
259 S>G No ClinGen
gnomAD
rs1208739825
CA367261371
260 Y>D No ClinGen
TOPMed
rs201063902
CA4215975
262 R>* No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA4215977
rs748353190
262 R>Q No ClinGen
ExAC
gnomAD
CA157286023
rs571901391
263 G>E No ClinGen
1000Genomes
CA367261394
rs1431189570
264 L>V No ClinGen
gnomAD
CA367261402
rs143774126
265 I>S No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs143774126
CA4215978
265 I>T No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs773154602
CA4215979
267 K>E No ClinGen
ExAC
gnomAD
rs146891651
CA4215980
268 A>E No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA157286032
rs867494594
268 A>T No ClinGen
gnomAD
rs1562769841
CA367261456
271 K>N No ClinGen
Ensembl
rs766163755
CA4215981
271 K>Q No ClinGen
ExAC
gnomAD
rs149004550
CA4215982
272 A>T No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA367261471
rs1205068707
273 I>V No ClinGen
gnomAD
rs1282766838
CA367261496
274 K>N No ClinGen
gnomAD
CA4215983
rs564191465
275 Y>C No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
CA4215984
rs764984258
276 S>C No ClinGen
ExAC
gnomAD
CA157286056
rs759018766
276 S>N No ClinGen
Ensembl
CA367261509
rs759018766
276 S>T No ClinGen
Ensembl
CA367261520
rs772009119
277 I>F No ClinGen
ExAC
TOPMed
gnomAD
TCGA novel 277 I>T Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA4215986
rs772009119
277 I>V No ClinGen
ExAC
TOPMed
gnomAD
CA4215987
rs762578459
278 I>T No ClinGen
ExAC
gnomAD
rs1385322333
CA367261549
279 I>S No ClinGen
gnomAD
CA4215988
rs763818231
279 I>V No ClinGen
ExAC
gnomAD
rs142805332
CA4215989
281 L>F No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs142805332
CA4215990
281 L>V No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA4215991
rs780380037
282 A>P No ClinGen
ExAC
TOPMed
gnomAD
rs956716609
CA157287075
284 I>V No ClinGen
TOPMed
gnomAD
rs778048013
CA4216014
285 C>F No ClinGen
ExAC
TOPMed
gnomAD
CA157287081
rs988569362
286 C>R No ClinGen
TOPMed
rs566491724
CA4216015
286 C>Y No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs77892941
CA4216016
287 W>* No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs1252697184
CA367261871
287 W>C No ClinGen
gnomAD
CA157287086
rs370674498
288 S>N No ClinGen
ESP
gnomAD
rs1342332441
CA367261878
288 S>R No ClinGen
gnomAD
CA367261882
rs1289553312
289 P>L Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
NCI-TCGA
TOPMed
gnomAD
rs962588749
CA367261881
289 P>S No ClinGen
gnomAD
rs962588749
CA157287091
289 P>T No ClinGen
gnomAD
rs781317985
CA4216017
292 L>P No ClinGen
ExAC
TOPMed
gnomAD
rs745958135
CA4216018
293 F>L No ClinGen
ExAC
TOPMed
gnomAD
CA4216019
rs769650749
293 F>S No ClinGen
ExAC
gnomAD
CA4216020
rs186466499
294 D>E No ClinGen
1000Genomes
ExAC
gnomAD
CA157287098
rs1028135599
294 D>H No ClinGen
TOPMed
rs751495123
CA157287104
295 I>S No ClinGen
Ensembl
rs1045222470
CA157287107
297 D>E No ClinGen
TOPMed
gnomAD
rs141001377
CA4216022
298 N>H No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1163044565
CA367261950
299 F>L No ClinGen
gnomAD
TCGA novel 304 D>N Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA367261987
rs1294567187
305 T>A No ClinGen
gnomAD
CA4216025
rs761525067
305 T>I No ClinGen
ExAC
gnomAD
CA4216024
rs761525067
305 T>N No ClinGen
ExAC
gnomAD
rs760266431
CA4216027
307 E>Q No ClinGen
ExAC
gnomAD
CA4216029
rs753232882
308 R>C No ClinGen
ExAC
gnomAD
rs189676025
CA4216030
308 R>H No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs764512468
CA4216031
311 A>S No ClinGen
ExAC
gnomAD
TCGA novel 312 S>F Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA367262053
rs10270766
315 I>N No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs10270766
VAR_025107
CA4216032
315 I>T No ClinGen
UniProt
1000Genomes
ESP
ExAC
TOPMed
dbSNP
gnomAD
COSM600859
rs1206648220
CA367262061
COSM600858
316 Q>H lung [Cosmic] No ClinGen
cosmic curated
gnomAD
CA367262066
rs1264169600
317 N>T No ClinGen
gnomAD
CA4216033
rs757439928
318 L>P No ClinGen
ExAC
TOPMed
gnomAD
rs781394302
CA4216034
319 P>Q No ClinGen
ExAC
gnomAD
rs745906142
CA4216035
320 A>S No ClinGen
ExAC
TOPMed
gnomAD
CA367262104
rs780159330
323 S>I No ClinGen
ExAC
gnomAD
rs780159330
CA4216037
323 S>N No ClinGen
ExAC
gnomAD
CA157287141
rs977424548
324 A>S No ClinGen
gnomAD
CA157287144
rs868044302
325 I>T No ClinGen
gnomAD
rs139125527
CA367262124
326 N>K No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA4216039
rs768547115
327 P>S No ClinGen
ExAC
TOPMed
gnomAD
CA367262126
rs768547115
327 P>T No ClinGen
ExAC
TOPMed
gnomAD
rs1451477873
CA367262142
329 I>S No ClinGen
gnomAD
rs774186892
CA4216041
330 Y>S No ClinGen
ExAC
TOPMed
gnomAD
CA4216043
rs572941013
331 C>S No ClinGen
ExAC
TOPMed
gnomAD
CA4216042
rs568443242
331 C>S No ClinGen
1000Genomes
ExAC
gnomAD
CA157287161
rs572941013
331 C>Y No ClinGen
ExAC
TOPMed
gnomAD
CA4216044
rs773031779
333 F>S No ClinGen
ExAC
TOPMed
gnomAD
CA4216045
rs142198576
335 S>R No ClinGen
ESP
ExAC
gnomAD
CA4216046
rs373901072
340 P>R No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1055134265
CA157287173
341 C>* Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
NCI-TCGA
gnomAD
rs149024595
CA157287426
342 R>= Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
Ensembl
NCI-TCGA
CA4216087
rs769162360
344 Q>* No ClinGen
ExAC
gnomAD
rs6972158
CA367262486
344 Q>L No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs6972158
VAR_023759
CA4216088
344 Q>R No ClinGen
UniProt
1000Genomes
ESP
ExAC
TOPMed
dbSNP
gnomAD
CA4216089
rs79459851
345 R>I No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs368052535
CA4216090
349 S>F No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs149313965
CA4216091
350 R>T No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs761033718
CA4216093
352 T>K No ClinGen
ExAC
TOPMed
gnomAD
CA4216092
rs761033718
352 T>M No ClinGen
ExAC
TOPMed
gnomAD
rs759852929
CA4216095
353 F>C No ClinGen
ExAC
gnomAD
rs77260034
CA4216097
354 R>Q No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs371959863
CA4216096
354 R>W No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs201655084
CA157287449
355 E>G No ClinGen
Ensembl
rs1265561987
CA367262571
355 E>K No ClinGen
TOPMed
rs1442234540
CA367262582
356 R>K Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
NCI-TCGA
gnomAD
CA367262593
rs1164991731
357 T>I No ClinGen
gnomAD
rs1279215770
CA367262601
358 E>D No ClinGen
TOPMed
CA157287455
rs377675594
358 E>K Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ESP
NCI-TCGA
TOPMed
gnomAD
rs1315994513
CA367262617
360 H>Q No ClinGen
gnomAD
CA4216099
rs144899362
361 E>* No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
CA367262619
rs144899362
361 E>Q No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs570630942
CA4216101
362 M>T No ClinGen
1000Genomes
ExAC
gnomAD
rs751356437
CA4216100
362 M>V No ClinGen
ExAC
gnomAD
rs79690462
CA157287461
364 I>V No ClinGen
Ensembl
rs781087458
CA367262649
365 L>P No ClinGen
ExAC
TOPMed
gnomAD
rs781087458
CA4216102
365 L>R No ClinGen
ExAC
TOPMed
gnomAD
CA157287465
rs530628552
366 S>C No ClinGen
Ensembl
rs770344450
CA157287467
368 P>S No ClinGen
Ensembl
rs200927809
CA4216104
371 I>S No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA4216103
rs145977047
371 I>V No ClinGen
ESP
ExAC
TOPMed
gnomAD
TCGA novel 372 I>Q Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA

No associated diseases with Q6W5P4

2 regional properties for Q6W5P4

Type Name Position InterPro Accession
domain GPCR, rhodopsin-like, 7TM 50 - 306 IPR017452
binding_site Visual pigments (opsins) retinal binding site 290 - 306 IPR027430

Functions

Description
EC Number
Subcellular Localization
  • [Isoform 1]: Cell membrane ; Multi-pass membrane protein
  • ;
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
neuropeptide receptor activity Combining with a neuropeptide to initiate a change in cell activity.
vasopressin receptor activity Combining with vasopressin to initiate a change in cell activity.

7 GO annotations of biological process

Name Definition
eating behavior The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
negative regulation of defecation Any process that stops, prevents or reduces the frequency, rate or extent of defecation.
negative regulation of eating behavior Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.
neuropeptide signaling pathway A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
positive regulation of ERK1 and ERK2 cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
positive regulation of release of sequestered calcium ion into cytosol Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
righting reflex A reflex process in which an animal immediately tries to turn over after being placed in a supine position.

127 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q58DT1 RPL7 60S ribosomal protein L7 Bos taurus (Bovine) PR
Q2YDN1 GPR161 G protein-coupled receptor 161 Bos taurus (Bovine) PR
Q0GBZ5 HCRTR1 Orexin/Hypocretin receptor type 1 Bos taurus (Bovine) PR
Q17QD8 GPR37L1 G-protein coupled receptor 37-like 1 Bos taurus (Bovine) PR
Q8SPN1 PROKR2 Prokineticin receptor 2 Bos taurus (Bovine) PR
P46626 ADRB3 Beta-3 adrenergic receptor Bos taurus (Bovine) PR
O46639 TRHR Thyrotropin-releasing hormone receptor Bos taurus (Bovine) PR
Q8SPN2 PROKR1 Prokineticin receptor 1 Bos taurus (Bovine) PR
B9VR26 CMLKR1 Chemerin-like receptor 1 Bos taurus (Bovine) PR
P18130 ADRA1A Alpha-1A adrenergic receptor Bos taurus (Bovine) PR
B4XF06 GPR39 G-protein coupled receptor 39 Bos taurus (Bovine) PR
O18913 OPN1LW Long-wave-sensitive opsin 1 Felis catus (Cat) (Felis silvestris catus) PR
P28683 PRA1 Green-sensitive opsin Gallus gallus (Chicken) PR
Q9N298 HTR1A 5-hydroxytryptamine receptor 1A Pan troglodytes (Chimpanzee) PR
P08099 Rh2 Opsin Rh2 Drosophila melanogaster (Fruit fly) PR
P06002 ninaE Opsin Rh1 Drosophila melanogaster (Fruit fly) PR
Q4LBB9 Octbeta2R Octopamine receptor beta-2R Drosophila melanogaster (Fruit fly) PR
P18124 RPL7 60S ribosomal protein L7 Homo sapiens (Human) PR
Q6DKI1 RPL7L1 60S ribosomal protein L7-like 1 Homo sapiens (Human) PR
Q8NFJ6 PROKR2 Prokineticin receptor 2 Homo sapiens (Human) PR
Q13585 GPR50 Melatonin-related receptor Homo sapiens (Human) PR
Q9BZJ6 GPR63 Probable G-protein coupled receptor 63 Homo sapiens (Human) PR
Q9H3N8 HRH4 Histamine H4 receptor Homo sapiens (Human) PR
P28336 NMBR Neuromedin-B receptor Homo sapiens (Human) PR
Q9Y5Y3 GPR45 Probable G-protein coupled receptor 45 Homo sapiens (Human) PR
P08913 ADRA2A Alpha-2A adrenergic receptor Homo sapiens (Human) PR
P41597 CCR2 C-C chemokine receptor type 2 Homo sapiens (Human) PR
P51681 CCR5 C-C chemokine receptor type 5 Homo sapiens (Human) PR
Q8TCW9 PROKR1 Prokineticin receptor 1 Homo sapiens (Human) PR
Q99788 CMKLR1 Chemerin-like receptor 1 Homo sapiens (Human) PR
P08908 HTR1A 5-hydroxytryptamine receptor 1A Homo sapiens (Human) PR
P30559 OXTR Oxytocin receptor Homo sapiens (Human) PR
P32239 CCKBR Gastrin/cholecystokinin type B receptor Homo sapiens (Human) PR
O60883 GPR37L1 G-protein coupled receptor 37-like 1 Homo sapiens (Human) PR
Q8TDU9 RXFP4 Relaxin-3 receptor 2 Homo sapiens (Human) PR
P04000 OPN1LW Long-wave-sensitive opsin 1 Homo sapiens (Human) PR
Q6U736 OPN5 Opsin-5 Homo sapiens (Human) PR
P34972 CNR2 Cannabinoid receptor 2 Homo sapiens (Human) PR
P24530 EDNRB Endothelin receptor type B Homo sapiens (Human) PR
P35348 ADRA1A Alpha-1A adrenergic receptor Homo sapiens (Human) PR
O43613 HCRTR1 Orexin/Hypocretin receptor type 1 Homo sapiens (Human) PR
P61073 CXCR4 C-X-C chemokine receptor type 4 Homo sapiens (Human) PR
Q9BXC0 HCAR1 Hydroxycarboxylic acid receptor 1 Homo sapiens (Human) PR
P30556 AGTR1 Type-1 angiotensin II receptor Homo sapiens (Human) PR
Q15761 NPY5R Neuropeptide Y receptor type 5 Homo sapiens (Human) PR
Q8N6U8 GPR161 G-protein coupled receptor 161 Homo sapiens (Human) PR
Q6DWJ6 GPR139 Probable G-protein coupled receptor 139 Homo sapiens (Human) PR
P21462 FPR1 fMet-Leu-Phe receptor Homo sapiens (Human) PR
P35414 APLNR Apelin receptor Homo sapiens (Human) PR
P46091 CMKLR2 Chemerin-like receptor 2 Homo sapiens (Human) PR
P32745 SSTR3 Somatostatin receptor type 3 Homo sapiens (Human) PR
P41439 FOLR3 Folate receptor gamma Homo sapiens (Human) PR
P14148 Rpl7 60S ribosomal protein L7 Mus musculus (Mouse) PR
Q9D8M4 Rpl7l1 60S ribosomal protein L7-like 1 Mus musculus (Mouse) PR
P19973 Lsp1 Lymphocyte-specific protein 1 Mus musculus (Mouse) PR
O54799 Nmbr Neuromedin-B receptor Mus musculus (Mouse) PR
Q64264 Htr1a 5-hydroxytryptamine receptor 1A Mus musculus (Mouse) PR
P51675 Ccr1 C-C chemokine receptor type 1 Mus musculus (Mouse) PR
Q5U431 Gpr39 G-protein coupled receptor 39 Mus musculus (Mouse) PR
Q99JG2 Gpr37l1 G-protein coupled receptor 37-like 1 Mus musculus (Mouse) PR
P97295 Npy2r Neuropeptide Y receptor type 2 Mus musculus (Mouse) PR
O08786 Cckar Cholecystokinin receptor type A Mus musculus (Mouse) PR
P56481 Cckbr Gastrin/cholecystokinin type B receptor Mus musculus (Mouse) PR
P30731 Gpr83 G-protein coupled receptor 83 Mus musculus (Mouse) PR
P97468 Cmklr1 Chemerin-like receptor 1 Mus musculus (Mouse) PR
P21761 Trhr Thyrotropin-releasing hormone receptor Mus musculus (Mouse) PR
Q5QD16 Taar3 Trace amine-associated receptor 3 Mus musculus (Mouse) PR
P97292 Hrh2 Histamine H2 receptor Mus musculus (Mouse) PR
Q9EQQ3 Gpr63 Probable G-protein coupled receptor 63 Mus musculus (Mouse) PR
Q924H0 Npffr2 Neuropeptide FF receptor 2 Mus musculus (Mouse) PR
P34971 Adrb1 Beta-1 adrenergic receptor Mus musculus (Mouse) PR
Q91ZY2 Hrh4 Histamine H4 receptor Mus musculus (Mouse) PR
O88416 Gpr33 Probable G-protein coupled receptor 33 Mus musculus (Mouse) PR
Q8K087 Cmklr2 Chemerin-like receptor 2 Mus musculus (Mouse) PR
P70658 Cxcr4 C-X-C chemokine receptor type 4 Mus musculus (Mouse) PR
Q9WV08 Aplnr Apelin receptor Mus musculus (Mouse) PR
P97718 Adra1a Alpha-1A adrenergic receptor Mus musculus (Mouse) PR
Q8K458 Prokr2 Prokineticin receptor 2 Mus musculus (Mouse) PR
P58308 Hcrtr2 Orexin receptor type 2 Mus musculus (Mouse) PR
Q7TQP3 Gpr119 Glucose-dependent insulinotropic receptor Mus musculus (Mouse) PR
Q8BGE9 Rxfp3 Relaxin-3 receptor 1 Mus musculus (Mouse) PR
Q6VZZ7 Opn5 Opsin-5 Mus musculus (Mouse) PR
Q8CIM5 Gpr84 G-protein coupled receptor 84 Mus musculus (Mouse) PR
P25962 Adrb3 Beta-3 adrenergic receptor Mus musculus (Mouse) PR
Q80UC8 Gpr139 Probable G-protein coupled receptor 139 Mus musculus (Mouse) PR
P0C5I1 Gpr25 Probable G-protein coupled receptor 25 Mus musculus (Mouse) PR
P47936 Cnr2 Cannabinoid receptor 2 Mus musculus (Mouse) PR
Q5QD13 Taar6 Trace amine-associated receptor 6 Mus musculus (Mouse) PR
P35846 Folr1 Folate receptor alpha Mus musculus (Mouse) PR
P58307 Hcrtr1 Orexin/Hypocretin receptor type 1 Mus musculus (Mouse) PR
Q8C131 Hcar1 Hydroxycarboxylic acid receptor 1 Mus musculus (Mouse) PR
Q9EQQ4 Gpr45 Probable G-protein coupled receptor 45 Mus musculus (Mouse) PR
B2RPY5 Gpr161 G-protein coupled receptor 161 Mus musculus (Mouse) PR
Q8BZP8 Npsr1 Neuropeptide S receptor Mus musculus (Mouse) PR
A5GFQ0 RPL7L1 60S ribosomal protein L7-like 1 Sus scrofa (Pig) PR
Q764M9 CXCR4 C-X-C chemokine receptor type 4 Sus scrofa (Pig) PR
P05426 Rpl7 60S ribosomal protein L7 Rattus norvegicus (Rat) PR
Q9EQD2 Npffr2 Neuropeptide FF receptor 2 Rattus norvegicus (Rat) PR
O08565 Cxcr4 C-X-C chemokine receptor type 4 Rattus norvegicus (Rat) PR
Q01717 Trhr Thyrotropin-releasing hormone receptor Rattus norvegicus (Rat) PR
P30936 Sstr3 Somatostatin receptor type 3 Rattus norvegicus (Rat) PR
Q9JHG3 Aplnr Apelin receptor Rattus norvegicus (Rat) PR
P43140 Adra1a Alpha-1A adrenergic receptor Rattus norvegicus (Rat) PR
P19327 Htr1a 5-hydroxytryptamine receptor 1A Rattus norvegicus (Rat) PR
P56719 Hcrtr2 Orexin receptor type 2 Rattus norvegicus (Rat) PR
P28564 Htr1b 5-hydroxytryptamine receptor 1B Rattus norvegicus (Rat) PR
P56718 Hcrtr1 Orexin/Hypocretin receptor type 1 Rattus norvegicus (Rat) PR
P28647 Adora3 Adenosine receptor A3 Rattus norvegicus (Rat) PR
P25102 Hrh2 Histamine H2 receptor Rattus norvegicus (Rat) PR
P23944 Adra1d Alpha-1D adrenergic receptor Rattus norvegicus (Rat) PR
Q8R415 Prokr2 Prokineticin receptor 2 Rattus norvegicus (Rat) PR
Q5QD24 Taar3 Trace amine-associated receptor 3 Rattus norvegicus (Rat) PR
P0C0W8 Gpr139 Probable G-protein coupled receptor 139 Rattus norvegicus (Rat) PR
P35370 Oprl1 Nociceptin receptor Rattus norvegicus (Rat) PR
P46090 Cmklr2 Chemerin-like receptor 2 Rattus norvegicus (Rat) PR
O97664 CMKLR2 Chemerin-like receptor 2 Macaca mulatta (Rhesus macaque) PR
O97666 APLNR Apelin receptor Macaca mulatta (Rhesus macaque) PR
Q56H79 NPSR1 Neuropeptide S receptor Macaca mulatta (Rhesus macaque) PR
Q18904 npr-8 Probable G-protein coupled receptor npr-8 Caenorhabditis elegans PR
Q09388 gar-2 Muscarinic acetylcholine receptor gar-2 Caenorhabditis elegans PR
P60039 RPL7C 60S ribosomal protein L7-3 Arabidopsis thaliana (Mouse-ear cress) PR
B3DM66 gpr161 G-protein coupled receptor 161 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q9W6A6 opn1mw4 Green-sensitive opsin-4 Danio rerio (Zebrafish) (Brachydanio rerio) PR
Q9W6A5 opn1mw1 Green-sensitive opsin-1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
Q8AYM7 opn1mw3 Green-sensitive opsin-3 Danio rerio (Zebrafish) (Brachydanio rerio) PR
Q8AYN0 opn1lw2 Red-sensitive opsin-2 Danio rerio (Zebrafish) (Brachydanio rerio) PR
Q90X46 gpr161 G-protein coupled receptor 161 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MPANFTEGSF DSSGTGQTLD SSPVACTETV TFTEVVEGKE WGSFYYSFKT EQLITLWVLF
70 80 90 100 110 120
VFTIVGNSVV LFSTWRRKKK SRMTFFVTQL AITDSFTGLV NILTDINWRF TGDFTAPDLV
130 140 150 160 170 180
CRVVRYLQVV LLYASTYVLV SLSIDRYHAI VYPMKFLQGE KQARVLIVIA WSLSFLFSIP
190 200 210 220 230 240
TLIIFGKRTL SNGEVQCWAL WPDDSYWTPY MTIVAFLVYF IPLTIISIMY GIVIRTIWIK
250 260 270 280 290 300
SKTYETVISN CSDGKLCSSY NRGLISKAKI KAIKYSIIII LAFICCWSPY FLFDILDNFN
310 320 330 340 350 360
LLPDTQERFY ASVIIQNLPA LNSAINPLIY CVFSSSISFP CREQRSQDSR MTFRERTERH
370
EMQILSKPEF I