Q6W5P4
Gene name |
NPSR1 (GPR154, GPRA, PGR14) |
Protein name |
Neuropeptide S receptor |
Names |
G-protein coupled receptor 154, G-protein coupled receptor PGR14, G-protein coupled receptor for asthma susceptibility |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:387129 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6W5P4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6W5P4-F1 | Predicted | AlphaFoldDB |
345 variants for Q6W5P4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
RCV000002276 CA115395 rs324981 VAR_023757 |
107 | N>I | Asthma-related traits, susceptibility to, 2 increases cell surface expression and NPS-dependent calcium mobilization; does not affect affinity for NPS. [ClinVar, UniProt] | Yes |
ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
CA367261449 rs1424178803 |
2 | P>S | No |
ClinGen gnomAD |
|
|
rs1363464526 CA367261462 |
3 | A>D | No |
ClinGen gnomAD |
|
|
rs766121315 CA4215635 |
3 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs753231326 CA4215636 |
5 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754542933 CA4215637 |
7 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs75375241 CA156859692 |
7 | E>D | No |
ClinGen Ensembl |
|
|
rs754542933 CA156859691 COSM1698535 COSM1698536 |
7 | E>K | Variant assessed as Somatic; 0.0 impact. skin [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs778384516 CA4215638 |
9 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA4215640 rs375686103 |
11 | D>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
COSM36651 CA156859694 rs267601495 |
11 | D>H | skin [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
CA156859693 rs267601495 |
11 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
| TCGA novel | 12 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA156859695 rs781670018 |
13 | S>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4215641 rs781670018 |
13 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA367261599 rs1385480995 |
14 | G>W | No |
ClinGen gnomAD |
|
|
rs1351919281 COSM3698381 COSM3698380 COSM3698382 COSM3698379 CA367261611 |
16 | G>E | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA367261609 rs769897360 CA4215643 |
16 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA4215644 rs775791206 |
17 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA367261624 rs149663215 |
18 | T>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4215645 rs149663215 |
18 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA4215647 rs115057146 |
19 | L>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA4215648 rs761714609 |
22 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1236178930 CA367261649 |
23 | P>S | No |
ClinGen gnomAD |
|
|
CA4215649 rs148428496 |
24 | V>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs772877468 CA4215650 |
25 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA4215652 rs765881654 |
26 | C>F | No |
ClinGen ExAC gnomAD |
|
|
CA367261673 rs1173975745 |
27 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
rs753560177 CA4215653 |
28 | E>A | No |
ClinGen ExAC gnomAD |
|
|
COSM107663 COSM107664 rs145130538 CA156859697 |
28 | E>K | skin [Cosmic] | No |
ClinGen cosmic curated Ensembl |
| TCGA novel | 29 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 31 | T>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1454882853 CA367261734 |
36 | V>A | No |
ClinGen TOPMed |
|
|
CA367261730 rs1246238293 |
36 | V>M | No |
ClinGen Ensembl |
|
|
rs757839925 CA4215657 |
37 | E>A | No |
ClinGen ExAC gnomAD |
|
|
rs757839925 CA156859698 |
37 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs781753839 CA4215658 |
38 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA4215659 rs201430808 |
40 | E>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 40 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4215660 rs201430808 |
40 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1480538286 CA367261765 |
41 | W>* | No |
ClinGen TOPMed |
|
|
CA367261773 rs1312232263 |
42 | G>D | No |
ClinGen gnomAD |
|
|
rs267601496 CA156859700 |
43 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA156859699 rs999562532 |
43 | S>P | No |
ClinGen Ensembl |
|
|
rs1562631240 CA367261789 |
45 | Y>H | No |
ClinGen Ensembl |
|
| TCGA novel | 46 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs116240309 CA156859701 |
47 | S>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1260501119 COSM746062 CA367261805 COSM746061 |
47 | S>P | lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA4215662 rs116240309 |
47 | S>Y | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA367260062 rs1349643308 |
51 | E>D | No |
ClinGen gnomAD |
|
|
rs1284529581 CA367260057 |
51 | E>Q | No |
ClinGen gnomAD |
|
|
COSM220240 COSM220239 CA4215692 rs543760020 |
53 | L>F | haematopoietic_and_lymphoid_tissue [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC gnomAD |
|
rs775283041 CA4215693 |
54 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs762509036 CA4215694 |
55 | T>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA367260123 rs1256090452 |
61 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs763680325 CA4215695 |
62 | F>L | No |
ClinGen ExAC |
|
|
CA156862515 rs751710810 |
62 | F>S | No |
ClinGen Ensembl |
|
|
rs751076118 CA4215696 |
63 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs755050843 CA4215697 |
63 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4215698 rs563652943 |
64 | I>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4215700 rs755348662 |
66 | G>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs116766176 CA4215699 |
66 | G>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA156862517 rs752940003 |
68 | S>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4215702 rs752940003 |
68 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777879974 CA4215704 |
69 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs75764081 CA4215703 |
69 | V>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1444302806 CA367260173 |
70 | V>L | No |
ClinGen gnomAD |
|
|
rs781296883 CA4215707 CA4215708 |
75 | W>R | No |
ClinGen ExAC gnomAD |
|
|
CA367260216 rs1255451409 |
76 | R>S | No |
ClinGen gnomAD |
|
|
CA4215710 rs769738896 |
79 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs369040738 CA156862518 |
80 | K>* | No |
ClinGen ESP TOPMed |
|
|
CA4215711 rs373297591 |
80 | K>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| rs752444500 | 80 | K>missing | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA367260245 rs1457600695 |
81 | S>A | No |
ClinGen gnomAD |
|
|
rs748946517 CA4215712 |
83 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA156862519 rs1038828004 |
84 | T>A | No |
ClinGen Ensembl |
|
|
rs1214003528 CA367260285 |
86 | F>L | No |
ClinGen gnomAD |
|
|
CA156862520 rs549686131 |
86 | F>S | No |
ClinGen TOPMed gnomAD |
|
|
CA4215714 rs768230329 |
87 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs1375476651 CA367260309 |
90 | L>R | No |
ClinGen gnomAD |
|
|
CA367260312 rs1467120948 |
91 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
CA4215715 rs773906121 |
93 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs761286205 CA4215716 |
94 | D>N | No |
ClinGen ExAC |
|
| TCGA novel | 94 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs565312186 CA4215741 |
95 | S>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1562720134 CA367260377 |
97 | T>I | No |
ClinGen Ensembl |
|
|
rs751765167 CA4215742 |
98 | G>* | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 101 | N>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA367260401 rs1432152237 |
101 | N>I | No |
ClinGen gnomAD |
|
|
rs933869553 CA157265144 |
102 | I>M | No |
ClinGen TOPMed gnomAD |
|
|
CA157265138 rs542257541 |
102 | I>T | No |
ClinGen gnomAD |
|
|
rs186967908 CA4215745 |
105 | D>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs960721012 CA157265196 |
105 | D>N | No |
ClinGen TOPMed |
|
|
CA4215747 rs756113542 |
106 | I>T | No |
ClinGen ExAC TOPMed |
|
|
CA4215748 rs780196686 |
107 | N>D | No |
ClinGen ExAC gnomAD |
|
|
rs324981 CA367260439 |
107 | N>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4215750 rs763039204 |
109 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs568145224 CA4215751 |
109 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs371040180 CA4215753 |
112 | G>E | No |
ClinGen ESP ExAC TOPMed |
|
|
CA367260468 rs1359443213 |
112 | G>R | No |
ClinGen gnomAD |
|
|
rs1301586831 CA367260474 |
113 | D>H | No |
ClinGen gnomAD |
|
|
CA4215755 rs375440531 |
115 | T>M | No |
ClinGen ESP ExAC gnomAD |
|
|
CA4215757 rs763341129 |
117 | P>R | No |
ClinGen ExAC gnomAD |
|
|
rs1449032125 CA367260508 |
118 | D>E | No |
ClinGen TOPMed |
|
|
CA4215760 rs762092370 |
118 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA4215759 rs368718436 |
118 | D>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4215758 rs368718436 |
118 | D>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1332310760 CA367260517 |
120 | V>A | No |
ClinGen TOPMed |
|
|
rs750515951 CA157265302 |
120 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750515951 CA4215762 |
120 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs202169485 CA4215763 |
122 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
COSM224936 rs35436513 VAR_025103 COSM224937 CA4215764 |
122 | R>Q | Variant assessed as Somatic; 0.0 impact. skin [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated UniProt 1000Genomes ESP ExAC NCI-TCGA TOPMed dbSNP gnomAD |
|
CA4215765 rs753750194 |
123 | V>E | No |
ClinGen ExAC gnomAD |
|
|
rs778542621 CA4215767 |
125 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1217747 COSM1217748 CA4215768 rs373742826 |
125 | R>H | large_intestine [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs368017225 CA4215770 |
126 | Y>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs542000666 CA157265355 |
126 | Y>S | No |
ClinGen 1000Genomes |
|
|
rs555318830 CA4215771 |
127 | L>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs78508704 CA157269003 |
129 | V>F | No |
ClinGen TOPMed gnomAD |
|
|
rs78508704 CA367259844 |
129 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
CA367259852 rs1193657013 |
130 | V>E | No |
ClinGen gnomAD |
|
|
COSM453002 rs376640561 COSM453003 CA4215793 |
132 | L>F | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs114775765 CA4215796 |
134 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA4215797 rs747202773 |
135 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs372990147 CA367259895 |
137 | Y>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA367259893 rs1365723924 |
137 | Y>C | No |
ClinGen gnomAD |
|
|
COSM3778413 CA4215799 rs376690361 COSM3778412 COSM3778414 |
138 | V>I | urinary_tract [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA4215800 rs759677549 |
141 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs325465 CA367259925 |
143 | S>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs325465 RCV000948764 CA4215801 VAR_025104 |
143 | S>G | No |
ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs325465 CA367259924 |
143 | S>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA367259936 rs1448314326 |
144 | I>T | No |
ClinGen TOPMed |
|
|
CA367259933 rs1186312421 |
144 | I>V | No |
ClinGen TOPMed |
|
|
CA4215802 rs775440956 |
145 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA367259938 rs1174888031 |
145 | D>H | No |
ClinGen TOPMed gnomAD |
|
|
rs143746221 CA4215803 |
146 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1360260807 CA367259957 |
147 | Y>* | No |
ClinGen gnomAD |
|
|
CA4215804 rs763858785 |
149 | A>P | No |
ClinGen ExAC gnomAD |
|
|
CA367259976 rs1193378029 |
150 | I>N | No |
ClinGen Ensembl |
|
|
rs756851967 CA4215806 |
151 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA157269086 rs756751266 |
153 | P>R | No |
ClinGen Ensembl |
|
|
rs767254511 CA4215807 |
153 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1438011853 CA367260000 |
154 | M>T | No |
ClinGen gnomAD |
|
|
rs1028773844 CA157269090 |
155 | K>N | No |
ClinGen Ensembl |
|
|
CA367260009 rs1227996795 |
155 | K>R | No |
ClinGen TOPMed |
|
|
rs755652890 CA4215809 |
157 | L>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs868156143 CA157269101 |
158 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs1343460838 CA367260704 |
160 | E>G | No |
ClinGen gnomAD |
|
|
CA4215810 rs200993440 |
160 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs200993440 CA157269119 |
160 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA367260710 rs1225773634 |
161 | K>E | No |
ClinGen gnomAD |
|
|
CA367260718 rs1350421370 |
162 | Q>* | No |
ClinGen TOPMed |
|
| TCGA novel | 162 | Q>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4215837 rs780099659 |
163 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4215839 rs569538789 |
164 | R>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs200741263 CA4215840 |
164 | R>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4215838 rs569538789 |
164 | R>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1017640284 CA157279326 |
165 | V>F | No |
ClinGen Ensembl |
|
|
CA4215841 rs761476084 |
166 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs377097496 CA4215842 |
167 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA367260753 rs1266746861 |
168 | V>A | No |
ClinGen gnomAD |
|
|
CA4215843 rs772930017 |
169 | I>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA367260759 rs772930017 |
169 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766192701 CA367260762 |
170 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM283351 CA4215845 COSM283350 COSM3663167 rs766192701 |
170 | A>T | Variant assessed as Somatic; 0.0 impact. liver large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 170 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1219928028 CA367260778 |
172 | S>N | No |
ClinGen TOPMed |
|
|
rs753340586 CA4215846 |
172 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 173 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4215848 rs764654607 |
175 | F>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1562759007 CA367260814 |
178 | S>P | No |
ClinGen Ensembl |
|
|
CA367260823 rs1562759014 |
179 | I>T | No |
ClinGen Ensembl |
|
|
CA367260820 rs1286017717 |
179 | I>V | No |
ClinGen TOPMed |
|
|
CA367260835 rs757750551 |
181 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4215850 rs757750551 |
181 | T>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1225904473 CA367260851 |
184 | I>V | No |
ClinGen gnomAD |
|
|
CA367260857 rs1284415024 |
185 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1295232920 CA367260864 |
186 | G>R | No |
ClinGen TOPMed |
|
|
rs749301919 CA367260900 |
191 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749301919 CA4215856 |
191 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA367260906 rs1159685581 |
192 | N>S | No |
ClinGen TOPMed |
|
|
rs778667665 CA4215858 |
193 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748097151 CA4215859 |
194 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA367260923 rs1433852698 |
195 | V>L | No |
ClinGen TOPMed |
|
|
CA4215860 rs34705969 VAR_025105 |
197 | C>F | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA367260939 rs34705969 |
197 | C>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4215861 rs114485438 |
197 | C>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 198 | W>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs552751963 CA367260956 |
200 | L>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA367260959 rs1172236826 |
200 | L>P | No |
ClinGen gnomAD |
|
|
rs776453644 CA4215864 |
201 | W>* | No |
ClinGen ExAC gnomAD |
|
|
CA4215865 rs759065076 |
202 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs150717138 CA4215867 |
203 | D>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs375118842 CA157279409 |
204 | D>H | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA157279405 rs375118842 |
204 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA TOPMed gnomAD |
|
CA4215868 rs762372799 |
206 | Y>* | No |
ClinGen ExAC gnomAD |
|
|
CA367260994 COSM3832709 COSM3832711 COSM3832710 rs1406844918 |
206 | Y>H | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA157279413 rs368352815 |
209 | P>A | No |
ClinGen ESP |
|
|
rs767970790 CA4215869 |
210 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
rs750745749 CA4215870 |
211 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs866505058 CA157279418 |
211 | M>V | No |
ClinGen gnomAD |
|
|
CA367261036 rs1327342373 |
212 | T>A | No |
ClinGen gnomAD |
|
|
rs35537374 CA4215871 VAR_025106 |
212 | T>I | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs754083738 CA4215874 |
214 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754083738 CA4215873 |
214 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1222565059 CA367261055 |
215 | A>V | No |
ClinGen gnomAD |
|
|
CA4215876 rs17170011 |
216 | F>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4215879 rs746759160 |
218 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1452290032 CA367261113 |
225 | I>V | No |
ClinGen gnomAD |
|
|
rs775056642 CA4215885 |
226 | I>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775056642 CA4215884 |
226 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA157283012 rs892058138 |
228 | I>V | No |
ClinGen Ensembl |
|
|
rs775960737 CA4215938 |
229 | M>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs916706976 CA157283014 |
229 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
CA4215939 rs763079218 |
232 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA4215941 rs751628759 |
235 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
COSM171609 rs116249859 COSM171608 CA4215942 |
235 | R>Q | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
CA4215944 rs767525853 |
241 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs727162 VAR_023758 CA4215945 |
241 | S>R | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1409654873 CA367261249 |
243 | T>N | No |
ClinGen TOPMed |
|
|
CA367261257 rs199565777 |
244 | Y>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA367261263 rs1403041686 |
245 | E>A | No |
ClinGen gnomAD |
|
|
CA4215948 rs140146458 |
245 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA157283047 rs1001718461 |
246 | T>I | No |
ClinGen Ensembl |
|
| TCGA novel | 246 | T>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4215949 rs754573421 |
247 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs778550553 CA4215950 |
250 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs1217772905 CA367261300 |
251 | C>S | No |
ClinGen TOPMed gnomAD |
|
|
rs747616486 CA367261308 |
252 | S>* | No |
ClinGen ExAC gnomAD |
|
|
rs747616486 CA4215951 |
252 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs907276853 CA157286009 |
253 | D>G | No |
ClinGen TOPMed |
|
|
CA4215974 rs373170949 |
258 | S>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs927577850 CA157286015 |
258 | S>R | No |
ClinGen Ensembl |
|
|
CA367261362 rs1365615076 |
259 | S>G | No |
ClinGen gnomAD |
|
|
rs1208739825 CA367261371 |
260 | Y>D | No |
ClinGen TOPMed |
|
|
rs201063902 CA4215975 |
262 | R>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4215977 rs748353190 |
262 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA157286023 rs571901391 |
263 | G>E | No |
ClinGen 1000Genomes |
|
|
CA367261394 rs1431189570 |
264 | L>V | No |
ClinGen gnomAD |
|
|
CA367261402 rs143774126 |
265 | I>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs143774126 CA4215978 |
265 | I>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs773154602 CA4215979 |
267 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs146891651 CA4215980 |
268 | A>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA157286032 rs867494594 |
268 | A>T | No |
ClinGen gnomAD |
|
|
rs1562769841 CA367261456 |
271 | K>N | No |
ClinGen Ensembl |
|
|
rs766163755 CA4215981 |
271 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
rs149004550 CA4215982 |
272 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA367261471 rs1205068707 |
273 | I>V | No |
ClinGen gnomAD |
|
|
rs1282766838 CA367261496 |
274 | K>N | No |
ClinGen gnomAD |
|
|
CA4215983 rs564191465 |
275 | Y>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4215984 rs764984258 |
276 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA157286056 rs759018766 |
276 | S>N | No |
ClinGen Ensembl |
|
|
CA367261509 rs759018766 |
276 | S>T | No |
ClinGen Ensembl |
|
|
CA367261520 rs772009119 |
277 | I>F | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 277 | I>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4215986 rs772009119 |
277 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4215987 rs762578459 |
278 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs1385322333 CA367261549 |
279 | I>S | No |
ClinGen gnomAD |
|
|
CA4215988 rs763818231 |
279 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs142805332 CA4215989 |
281 | L>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs142805332 CA4215990 |
281 | L>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4215991 rs780380037 |
282 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs956716609 CA157287075 |
284 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs778048013 CA4216014 |
285 | C>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA157287081 rs988569362 |
286 | C>R | No |
ClinGen TOPMed |
|
|
rs566491724 CA4216015 |
286 | C>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs77892941 CA4216016 |
287 | W>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1252697184 CA367261871 |
287 | W>C | No |
ClinGen gnomAD |
|
|
CA157287086 rs370674498 |
288 | S>N | No |
ClinGen ESP gnomAD |
|
|
rs1342332441 CA367261878 |
288 | S>R | No |
ClinGen gnomAD |
|
|
CA367261882 rs1289553312 |
289 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs962588749 CA367261881 |
289 | P>S | No |
ClinGen gnomAD |
|
|
rs962588749 CA157287091 |
289 | P>T | No |
ClinGen gnomAD |
|
|
rs781317985 CA4216017 |
292 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs745958135 CA4216018 |
293 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4216019 rs769650749 |
293 | F>S | No |
ClinGen ExAC gnomAD |
|
|
CA4216020 rs186466499 |
294 | D>E | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA157287098 rs1028135599 |
294 | D>H | No |
ClinGen TOPMed |
|
|
rs751495123 CA157287104 |
295 | I>S | No |
ClinGen Ensembl |
|
|
rs1045222470 CA157287107 |
297 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
rs141001377 CA4216022 |
298 | N>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1163044565 CA367261950 |
299 | F>L | No |
ClinGen gnomAD |
|
| TCGA novel | 304 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA367261987 rs1294567187 |
305 | T>A | No |
ClinGen gnomAD |
|
|
CA4216025 rs761525067 |
305 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA4216024 rs761525067 |
305 | T>N | No |
ClinGen ExAC gnomAD |
|
|
rs760266431 CA4216027 |
307 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA4216029 rs753232882 |
308 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs189676025 CA4216030 |
308 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs764512468 CA4216031 |
311 | A>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 312 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA367262053 rs10270766 |
315 | I>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs10270766 VAR_025107 CA4216032 |
315 | I>T | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
COSM600859 rs1206648220 CA367262061 COSM600858 |
316 | Q>H | lung [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA367262066 rs1264169600 |
317 | N>T | No |
ClinGen gnomAD |
|
|
CA4216033 rs757439928 |
318 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781394302 CA4216034 |
319 | P>Q | No |
ClinGen ExAC gnomAD |
|
|
rs745906142 CA4216035 |
320 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA367262104 rs780159330 |
323 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs780159330 CA4216037 |
323 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA157287141 rs977424548 |
324 | A>S | No |
ClinGen gnomAD |
|
|
CA157287144 rs868044302 |
325 | I>T | No |
ClinGen gnomAD |
|
|
rs139125527 CA367262124 |
326 | N>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4216039 rs768547115 |
327 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA367262126 rs768547115 |
327 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1451477873 CA367262142 |
329 | I>S | No |
ClinGen gnomAD |
|
|
rs774186892 CA4216041 |
330 | Y>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4216043 rs572941013 |
331 | C>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4216042 rs568443242 |
331 | C>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA157287161 rs572941013 |
331 | C>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4216044 rs773031779 |
333 | F>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4216045 rs142198576 |
335 | S>R | No |
ClinGen ESP ExAC gnomAD |
|
|
CA4216046 rs373901072 |
340 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1055134265 CA157287173 |
341 | C>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs149024595 CA157287426 |
342 | R>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA4216087 rs769162360 |
344 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs6972158 CA367262486 |
344 | Q>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs6972158 VAR_023759 CA4216088 |
344 | Q>R | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA4216089 rs79459851 |
345 | R>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs368052535 CA4216090 |
349 | S>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs149313965 CA4216091 |
350 | R>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs761033718 CA4216093 |
352 | T>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4216092 rs761033718 |
352 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759852929 CA4216095 |
353 | F>C | No |
ClinGen ExAC gnomAD |
|
|
rs77260034 CA4216097 |
354 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs371959863 CA4216096 |
354 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs201655084 CA157287449 |
355 | E>G | No |
ClinGen Ensembl |
|
|
rs1265561987 CA367262571 |
355 | E>K | No |
ClinGen TOPMed |
|
|
rs1442234540 CA367262582 |
356 | R>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA367262593 rs1164991731 |
357 | T>I | No |
ClinGen gnomAD |
|
|
rs1279215770 CA367262601 |
358 | E>D | No |
ClinGen TOPMed |
|
|
CA157287455 rs377675594 |
358 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA TOPMed gnomAD |
|
rs1315994513 CA367262617 |
360 | H>Q | No |
ClinGen gnomAD |
|
|
CA4216099 rs144899362 |
361 | E>* | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA367262619 rs144899362 |
361 | E>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs570630942 CA4216101 |
362 | M>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs751356437 CA4216100 |
362 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs79690462 CA157287461 |
364 | I>V | No |
ClinGen Ensembl |
|
|
rs781087458 CA367262649 |
365 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781087458 CA4216102 |
365 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA157287465 rs530628552 |
366 | S>C | No |
ClinGen Ensembl |
|
|
rs770344450 CA157287467 |
368 | P>S | No |
ClinGen Ensembl |
|
|
rs200927809 CA4216104 |
371 | I>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4216103 rs145977047 |
371 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 372 | I>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
No associated diseases with Q6W5P4
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| neuropeptide receptor activity | Combining with a neuropeptide to initiate a change in cell activity. |
| vasopressin receptor activity | Combining with vasopressin to initiate a change in cell activity. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| eating behavior | The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue. |
| negative regulation of defecation | Any process that stops, prevents or reduces the frequency, rate or extent of defecation. |
| negative regulation of eating behavior | Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior. |
| neuropeptide signaling pathway | A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. |
| positive regulation of ERK1 and ERK2 cascade | Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. |
| positive regulation of release of sequestered calcium ion into cytosol | Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. |
| righting reflex | A reflex process in which an animal immediately tries to turn over after being placed in a supine position. |
127 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q58DT1 | RPL7 | 60S ribosomal protein L7 | Bos taurus (Bovine) | PR |
| Q2YDN1 | GPR161 | G protein-coupled receptor 161 | Bos taurus (Bovine) | PR |
| Q0GBZ5 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Bos taurus (Bovine) | PR |
| Q17QD8 | GPR37L1 | G-protein coupled receptor 37-like 1 | Bos taurus (Bovine) | PR |
| Q8SPN1 | PROKR2 | Prokineticin receptor 2 | Bos taurus (Bovine) | PR |
| P46626 | ADRB3 | Beta-3 adrenergic receptor | Bos taurus (Bovine) | PR |
| O46639 | TRHR | Thyrotropin-releasing hormone receptor | Bos taurus (Bovine) | PR |
| Q8SPN2 | PROKR1 | Prokineticin receptor 1 | Bos taurus (Bovine) | PR |
| B9VR26 | CMLKR1 | Chemerin-like receptor 1 | Bos taurus (Bovine) | PR |
| P18130 | ADRA1A | Alpha-1A adrenergic receptor | Bos taurus (Bovine) | PR |
| B4XF06 | GPR39 | G-protein coupled receptor 39 | Bos taurus (Bovine) | PR |
| O18913 | OPN1LW | Long-wave-sensitive opsin 1 | Felis catus (Cat) (Felis silvestris catus) | PR |
| P28683 | PRA1 | Green-sensitive opsin | Gallus gallus (Chicken) | PR |
| Q9N298 | HTR1A | 5-hydroxytryptamine receptor 1A | Pan troglodytes (Chimpanzee) | PR |
| P08099 | Rh2 | Opsin Rh2 | Drosophila melanogaster (Fruit fly) | PR |
| P06002 | ninaE | Opsin Rh1 | Drosophila melanogaster (Fruit fly) | PR |
| Q4LBB9 | Octbeta2R | Octopamine receptor beta-2R | Drosophila melanogaster (Fruit fly) | PR |
| P18124 | RPL7 | 60S ribosomal protein L7 | Homo sapiens (Human) | PR |
| Q6DKI1 | RPL7L1 | 60S ribosomal protein L7-like 1 | Homo sapiens (Human) | PR |
| Q8NFJ6 | PROKR2 | Prokineticin receptor 2 | Homo sapiens (Human) | PR |
| Q13585 | GPR50 | Melatonin-related receptor | Homo sapiens (Human) | PR |
| Q9BZJ6 | GPR63 | Probable G-protein coupled receptor 63 | Homo sapiens (Human) | PR |
| Q9H3N8 | HRH4 | Histamine H4 receptor | Homo sapiens (Human) | PR |
| P28336 | NMBR | Neuromedin-B receptor | Homo sapiens (Human) | PR |
| Q9Y5Y3 | GPR45 | Probable G-protein coupled receptor 45 | Homo sapiens (Human) | PR |
| P08913 | ADRA2A | Alpha-2A adrenergic receptor | Homo sapiens (Human) | PR |
| P41597 | CCR2 | C-C chemokine receptor type 2 | Homo sapiens (Human) | PR |
| P51681 | CCR5 | C-C chemokine receptor type 5 | Homo sapiens (Human) | PR |
| Q8TCW9 | PROKR1 | Prokineticin receptor 1 | Homo sapiens (Human) | PR |
| Q99788 | CMKLR1 | Chemerin-like receptor 1 | Homo sapiens (Human) | PR |
| P08908 | HTR1A | 5-hydroxytryptamine receptor 1A | Homo sapiens (Human) | PR |
| P30559 | OXTR | Oxytocin receptor | Homo sapiens (Human) | PR |
| P32239 | CCKBR | Gastrin/cholecystokinin type B receptor | Homo sapiens (Human) | PR |
| O60883 | GPR37L1 | G-protein coupled receptor 37-like 1 | Homo sapiens (Human) | PR |
| Q8TDU9 | RXFP4 | Relaxin-3 receptor 2 | Homo sapiens (Human) | PR |
| P04000 | OPN1LW | Long-wave-sensitive opsin 1 | Homo sapiens (Human) | PR |
| Q6U736 | OPN5 | Opsin-5 | Homo sapiens (Human) | PR |
| P34972 | CNR2 | Cannabinoid receptor 2 | Homo sapiens (Human) | PR |
| P24530 | EDNRB | Endothelin receptor type B | Homo sapiens (Human) | PR |
| P35348 | ADRA1A | Alpha-1A adrenergic receptor | Homo sapiens (Human) | PR |
| O43613 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Homo sapiens (Human) | PR |
| P61073 | CXCR4 | C-X-C chemokine receptor type 4 | Homo sapiens (Human) | PR |
| Q9BXC0 | HCAR1 | Hydroxycarboxylic acid receptor 1 | Homo sapiens (Human) | PR |
| P30556 | AGTR1 | Type-1 angiotensin II receptor | Homo sapiens (Human) | PR |
| Q15761 | NPY5R | Neuropeptide Y receptor type 5 | Homo sapiens (Human) | PR |
| Q8N6U8 | GPR161 | G-protein coupled receptor 161 | Homo sapiens (Human) | PR |
| Q6DWJ6 | GPR139 | Probable G-protein coupled receptor 139 | Homo sapiens (Human) | PR |
| P21462 | FPR1 | fMet-Leu-Phe receptor | Homo sapiens (Human) | PR |
| P35414 | APLNR | Apelin receptor | Homo sapiens (Human) | PR |
| P46091 | CMKLR2 | Chemerin-like receptor 2 | Homo sapiens (Human) | PR |
| P32745 | SSTR3 | Somatostatin receptor type 3 | Homo sapiens (Human) | PR |
| P41439 | FOLR3 | Folate receptor gamma | Homo sapiens (Human) | PR |
| P14148 | Rpl7 | 60S ribosomal protein L7 | Mus musculus (Mouse) | PR |
| Q9D8M4 | Rpl7l1 | 60S ribosomal protein L7-like 1 | Mus musculus (Mouse) | PR |
| P19973 | Lsp1 | Lymphocyte-specific protein 1 | Mus musculus (Mouse) | PR |
| O54799 | Nmbr | Neuromedin-B receptor | Mus musculus (Mouse) | PR |
| Q64264 | Htr1a | 5-hydroxytryptamine receptor 1A | Mus musculus (Mouse) | PR |
| P51675 | Ccr1 | C-C chemokine receptor type 1 | Mus musculus (Mouse) | PR |
| Q5U431 | Gpr39 | G-protein coupled receptor 39 | Mus musculus (Mouse) | PR |
| Q99JG2 | Gpr37l1 | G-protein coupled receptor 37-like 1 | Mus musculus (Mouse) | PR |
| P97295 | Npy2r | Neuropeptide Y receptor type 2 | Mus musculus (Mouse) | PR |
| O08786 | Cckar | Cholecystokinin receptor type A | Mus musculus (Mouse) | PR |
| P56481 | Cckbr | Gastrin/cholecystokinin type B receptor | Mus musculus (Mouse) | PR |
| P30731 | Gpr83 | G-protein coupled receptor 83 | Mus musculus (Mouse) | PR |
| P97468 | Cmklr1 | Chemerin-like receptor 1 | Mus musculus (Mouse) | PR |
| P21761 | Trhr | Thyrotropin-releasing hormone receptor | Mus musculus (Mouse) | PR |
| Q5QD16 | Taar3 | Trace amine-associated receptor 3 | Mus musculus (Mouse) | PR |
| P97292 | Hrh2 | Histamine H2 receptor | Mus musculus (Mouse) | PR |
| Q9EQQ3 | Gpr63 | Probable G-protein coupled receptor 63 | Mus musculus (Mouse) | PR |
| Q924H0 | Npffr2 | Neuropeptide FF receptor 2 | Mus musculus (Mouse) | PR |
| P34971 | Adrb1 | Beta-1 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q91ZY2 | Hrh4 | Histamine H4 receptor | Mus musculus (Mouse) | PR |
| O88416 | Gpr33 | Probable G-protein coupled receptor 33 | Mus musculus (Mouse) | PR |
| Q8K087 | Cmklr2 | Chemerin-like receptor 2 | Mus musculus (Mouse) | PR |
| P70658 | Cxcr4 | C-X-C chemokine receptor type 4 | Mus musculus (Mouse) | PR |
| Q9WV08 | Aplnr | Apelin receptor | Mus musculus (Mouse) | PR |
| P97718 | Adra1a | Alpha-1A adrenergic receptor | Mus musculus (Mouse) | PR |
| Q8K458 | Prokr2 | Prokineticin receptor 2 | Mus musculus (Mouse) | PR |
| P58308 | Hcrtr2 | Orexin receptor type 2 | Mus musculus (Mouse) | PR |
| Q7TQP3 | Gpr119 | Glucose-dependent insulinotropic receptor | Mus musculus (Mouse) | PR |
| Q8BGE9 | Rxfp3 | Relaxin-3 receptor 1 | Mus musculus (Mouse) | PR |
| Q6VZZ7 | Opn5 | Opsin-5 | Mus musculus (Mouse) | PR |
| Q8CIM5 | Gpr84 | G-protein coupled receptor 84 | Mus musculus (Mouse) | PR |
| P25962 | Adrb3 | Beta-3 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q80UC8 | Gpr139 | Probable G-protein coupled receptor 139 | Mus musculus (Mouse) | PR |
| P0C5I1 | Gpr25 | Probable G-protein coupled receptor 25 | Mus musculus (Mouse) | PR |
| P47936 | Cnr2 | Cannabinoid receptor 2 | Mus musculus (Mouse) | PR |
| Q5QD13 | Taar6 | Trace amine-associated receptor 6 | Mus musculus (Mouse) | PR |
| P35846 | Folr1 | Folate receptor alpha | Mus musculus (Mouse) | PR |
| P58307 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Mus musculus (Mouse) | PR |
| Q8C131 | Hcar1 | Hydroxycarboxylic acid receptor 1 | Mus musculus (Mouse) | PR |
| Q9EQQ4 | Gpr45 | Probable G-protein coupled receptor 45 | Mus musculus (Mouse) | PR |
| B2RPY5 | Gpr161 | G-protein coupled receptor 161 | Mus musculus (Mouse) | PR |
| Q8BZP8 | Npsr1 | Neuropeptide S receptor | Mus musculus (Mouse) | PR |
| A5GFQ0 | RPL7L1 | 60S ribosomal protein L7-like 1 | Sus scrofa (Pig) | PR |
| Q764M9 | CXCR4 | C-X-C chemokine receptor type 4 | Sus scrofa (Pig) | PR |
| P05426 | Rpl7 | 60S ribosomal protein L7 | Rattus norvegicus (Rat) | PR |
| Q9EQD2 | Npffr2 | Neuropeptide FF receptor 2 | Rattus norvegicus (Rat) | PR |
| O08565 | Cxcr4 | C-X-C chemokine receptor type 4 | Rattus norvegicus (Rat) | PR |
| Q01717 | Trhr | Thyrotropin-releasing hormone receptor | Rattus norvegicus (Rat) | PR |
| P30936 | Sstr3 | Somatostatin receptor type 3 | Rattus norvegicus (Rat) | PR |
| Q9JHG3 | Aplnr | Apelin receptor | Rattus norvegicus (Rat) | PR |
| P43140 | Adra1a | Alpha-1A adrenergic receptor | Rattus norvegicus (Rat) | PR |
| P19327 | Htr1a | 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Rat) | PR |
| P56719 | Hcrtr2 | Orexin receptor type 2 | Rattus norvegicus (Rat) | PR |
| P28564 | Htr1b | 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Rat) | PR |
| P56718 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Rattus norvegicus (Rat) | PR |
| P28647 | Adora3 | Adenosine receptor A3 | Rattus norvegicus (Rat) | PR |
| P25102 | Hrh2 | Histamine H2 receptor | Rattus norvegicus (Rat) | PR |
| P23944 | Adra1d | Alpha-1D adrenergic receptor | Rattus norvegicus (Rat) | PR |
| Q8R415 | Prokr2 | Prokineticin receptor 2 | Rattus norvegicus (Rat) | PR |
| Q5QD24 | Taar3 | Trace amine-associated receptor 3 | Rattus norvegicus (Rat) | PR |
| P0C0W8 | Gpr139 | Probable G-protein coupled receptor 139 | Rattus norvegicus (Rat) | PR |
| P35370 | Oprl1 | Nociceptin receptor | Rattus norvegicus (Rat) | PR |
| P46090 | Cmklr2 | Chemerin-like receptor 2 | Rattus norvegicus (Rat) | PR |
| O97664 | CMKLR2 | Chemerin-like receptor 2 | Macaca mulatta (Rhesus macaque) | PR |
| O97666 | APLNR | Apelin receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q56H79 | NPSR1 | Neuropeptide S receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q18904 | npr-8 | Probable G-protein coupled receptor npr-8 | Caenorhabditis elegans | PR |
| Q09388 | gar-2 | Muscarinic acetylcholine receptor gar-2 | Caenorhabditis elegans | PR |
| P60039 | RPL7C | 60S ribosomal protein L7-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| B3DM66 | gpr161 | G-protein coupled receptor 161 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q9W6A6 | opn1mw4 | Green-sensitive opsin-4 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q9W6A5 | opn1mw1 | Green-sensitive opsin-1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYM7 | opn1mw3 | Green-sensitive opsin-3 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYN0 | opn1lw2 | Red-sensitive opsin-2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q90X46 | gpr161 | G-protein coupled receptor 161 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPANFTEGSF | DSSGTGQTLD | SSPVACTETV | TFTEVVEGKE | WGSFYYSFKT | EQLITLWVLF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VFTIVGNSVV | LFSTWRRKKK | SRMTFFVTQL | AITDSFTGLV | NILTDINWRF | TGDFTAPDLV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CRVVRYLQVV | LLYASTYVLV | SLSIDRYHAI | VYPMKFLQGE | KQARVLIVIA | WSLSFLFSIP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TLIIFGKRTL | SNGEVQCWAL | WPDDSYWTPY | MTIVAFLVYF | IPLTIISIMY | GIVIRTIWIK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SKTYETVISN | CSDGKLCSSY | NRGLISKAKI | KAIKYSIIII | LAFICCWSPY | FLFDILDNFN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLPDTQERFY | ASVIIQNLPA | LNSAINPLIY | CVFSSSISFP | CREQRSQDSR | MTFRERTERH |
| 370 | |||||
| EMQILSKPEF | I |