Q9H3N8
PR
Gene name |
HRH4 (GPCR105) |
Protein name |
Histamine H4 receptor |
Names |
H4R, HH4R, AXOR35, G-protein coupled receptor 105, GPRv53, Pfi-013, SP9144 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:59340 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
5 structures for Q9H3N8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7YFC | EM | 300 A | R | 1-390 | PDB |
| 7YFD | EM | 310 A | R | 1-390 | PDB |
| 8HN8 | EM | 300 A | R | 4-390 | PDB |
| 8HOC | EM | 300 A | R | 4-390 | PDB |
| AF-Q9H3N8-F1 | Predicted | AlphaFoldDB |
302 variants for Q9H3N8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA402080983 rs1280694062 |
2 | P>A | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 4 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1319377251 CA402080999 |
4 | T>I | No |
ClinGen gnomAD |
|
|
CA297146731 rs953923437 |
5 | N>H | No |
ClinGen TOPMed |
|
|
rs763077385 CA8919698 |
6 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA8919699 rs148759744 |
7 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1253001271 CA402081027 |
9 | N>H | No |
ClinGen TOPMed |
|
|
CA8919703 rs753662175 |
12 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA8919705 rs764937377 |
14 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8919704 rs759524396 |
14 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA297146780 rs915066300 |
15 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs752596225 CA8919706 |
15 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 16 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs758027653 CA8919707 |
16 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8919708 rs763780845 |
17 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA402081098 rs1276645749 |
20 | F>L | No |
ClinGen gnomAD |
|
| TCGA novel | 20 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8919711 rs756709978 |
21 | F>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA297146804 rs1046743172 |
22 | M>I | No |
ClinGen TOPMed gnomAD |
|
|
CA8919713 rs746290703 |
23 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA402081121 rs1259376259 |
24 | L>* | No |
ClinGen gnomAD |
|
|
CA8919714 rs756707102 |
24 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs1450064221 CA402081145 |
28 | A>T | No |
ClinGen gnomAD |
|
| TCGA novel | 28 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1169133590 CA402081153 |
29 | I>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA402081164 rs1422530312 |
30 | M>I | No |
ClinGen gnomAD |
|
|
rs1413488598 CA402081168 |
31 | L>V | No |
ClinGen gnomAD |
|
|
rs1361212669 CA402081188 |
34 | A>S | No |
ClinGen gnomAD |
|
|
CA402081209 rs1366526991 |
37 | I>M | No |
ClinGen gnomAD |
|
|
CA8919718 rs768968709 |
37 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs749718845 CA8919717 |
37 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA402081230 rs1402626198 |
40 | F>L | No |
ClinGen TOPMed |
|
|
rs1437970329 CA402081231 |
41 | V>M | No |
ClinGen gnomAD |
|
|
rs1273146424 CA402081243 |
43 | D>N | No |
ClinGen gnomAD |
|
|
CA402081252 rs1219988570 |
44 | K>E | No |
ClinGen gnomAD |
|
|
rs377165171 CA8919720 |
44 | K>R | No |
ClinGen ESP ExAC gnomAD |
|
|
rs773411086 CA297146845 |
45 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs184989207 CA8919721 |
45 | N>S | No |
ClinGen 1000Genomes ExAC TOPMed |
|
|
CA8919724 COSM1209976 rs765269581 |
49 | R>* | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA402081285 rs765269581 |
49 | R>G | No |
ClinGen ExAC gnomAD |
|
|
COSM987192 rs775120560 CA8919725 |
49 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs762701153 CA8919726 |
50 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1599773091 CA402081295 |
51 | S>R | No |
ClinGen Ensembl |
|
|
CA402081310 rs1204924816 |
52 | Y>* | No |
ClinGen Ensembl |
|
|
rs1244414119 CA402081304 |
52 | Y>H | No |
ClinGen gnomAD |
|
|
CA8919727 rs763901600 |
53 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751158644 CA8919728 |
54 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs142480341 CA297146913 |
57 | L>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs142480341 CA8919730 |
57 | L>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1402881096 CA402081347 |
58 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs200830814 CA297146935 |
59 | I>V | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs372826759 CA297146938 |
60 | S>A | No |
ClinGen Ensembl |
|
|
rs1459658537 CA402081362 |
61 | D>H | No |
ClinGen gnomAD |
|
|
rs1276741673 CA402081378 |
63 | F>L | No |
ClinGen gnomAD |
|
|
rs760192203 CA8919751 |
65 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402081760 rs1209506672 |
67 | I>V | No |
ClinGen TOPMed |
|
|
rs1037174077 CA297151509 |
68 | S>F | No |
ClinGen Ensembl |
|
|
rs1217084990 CA402081765 |
68 | S>T | No |
ClinGen TOPMed gnomAD |
|
|
CA8919752 rs765826743 |
69 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA8919753 rs754336963 |
70 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs779410233 CA8919755 |
73 | I>L | No |
ClinGen ExAC gnomAD |
|
|
rs146877850 CA8919756 |
76 | T>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1054769052 CA297151521 |
77 | L>M | No |
ClinGen TOPMed |
|
|
rs1473374180 CA402081826 |
78 | F>L | No |
ClinGen gnomAD |
|
|
rs747220498 CA8919759 |
79 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA8919761 rs770990012 |
80 | W>L | No |
ClinGen ExAC gnomAD |
|
|
rs1404400019 CA402081848 |
81 | D>N | No |
ClinGen TOPMed |
|
|
rs373246547 CA8919763 |
83 | G>E | No |
ClinGen ESP ExAC gnomAD |
|
|
CA8919762 rs781258002 |
83 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs768633995 CA8919764 |
85 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA297151537 rs910874713 |
86 | I>F | No |
ClinGen TOPMed gnomAD |
|
|
CA297151543 rs375203892 |
86 | I>N | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA402081886 rs375203892 |
86 | I>T | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA8919767 COSM148411 rs80252896 |
88 | V>G | stomach [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA402081896 rs774108097 |
88 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs774108097 CA8919766 |
88 | V>L | No |
ClinGen ExAC gnomAD |
|
|
rs771792972 CA8919768 |
90 | W>* | No |
ClinGen ExAC |
|
|
CA402081920 rs1227001218 |
91 | L>P | No |
ClinGen gnomAD |
|
|
rs771552631 CA8919770 |
93 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1198377600 CA402081946 |
95 | Y>S | No |
ClinGen gnomAD |
|
|
rs760258503 COSM417878 CA402081950 |
96 | L>V | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA297151571 rs902335865 |
97 | L>F | No |
ClinGen Ensembl |
|
|
rs1443377753 CA402081961 |
98 | C>R | No |
ClinGen gnomAD |
|
|
CA402081977 rs1185924864 |
100 | A>E | No |
ClinGen TOPMed gnomAD |
|
|
CA402081979 rs1185924864 |
100 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA402081980 rs1449443009 |
101 | S>T | No |
ClinGen gnomAD |
|
|
CA402081991 rs1169285626 |
102 | V>G | No |
ClinGen gnomAD |
|
|
CA402082012 rs1464670264 |
105 | I>T | No |
ClinGen gnomAD |
|
|
CA8919775 rs140250696 |
109 | S>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs753290433 CA402082040 |
109 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs878961770 CA297151603 |
110 | Y>S | No |
ClinGen Ensembl |
|
|
rs758743592 CA8919777 |
111 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA8919778 rs778017267 |
112 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA8919779 rs751742130 COSM987195 |
112 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1434620794 CA402082076 |
115 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA402082081 rs1295593193 |
116 | V>D | No |
ClinGen gnomAD |
|
|
CA402082087 COSM708267 rs1379260154 |
117 | S>* | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
CA402082084 rs1303974510 |
117 | S>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1308762388 CA402082096 |
118 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
CA402082408 rs1209307755 |
120 | V>A | No |
ClinGen gnomAD |
|
|
CA8919795 rs764865289 |
120 | V>L | No |
ClinGen ExAC gnomAD |
|
|
rs892168399 CA297155724 |
122 | Y>C | No |
ClinGen Ensembl |
|
|
rs776009766 CA8919796 |
122 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
rs763378382 CA8919797 |
123 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs1462297615 COSM1680287 CA402082445 |
123 | R>I | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs764386766 CA297155738 CA402082474 |
125 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA297155740 rs894564616 |
127 | T>S | No |
ClinGen TOPMed |
|
|
rs767733893 CA8919799 |
129 | V>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1321327368 CA402082554 |
132 | I>F | No |
ClinGen TOPMed |
|
|
CA402082561 rs1599781021 |
132 | I>T | No |
ClinGen Ensembl |
|
|
CA402082578 rs1310900798 |
133 | V>A | No |
ClinGen TOPMed |
|
|
CA297155744 rs995965195 |
134 | T>A | No |
ClinGen TOPMed |
|
|
rs1159616683 CA402082593 |
134 | T>I | No |
ClinGen gnomAD |
|
|
rs143995992 CA8919801 |
136 | M>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1365663685 CA402082614 |
136 | M>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs11665084 VAR_033477 CA8919802 |
138 | A>V | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA8919804 rs780120010 |
139 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA297155811 rs953437853 |
141 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA402082673 rs953437853 |
141 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
rs116172621 CA8919807 |
143 | A>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8919806 rs116172621 |
143 | A>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8919808 rs777602176 |
143 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1437703802 CA402082703 |
145 | L>S | No |
ClinGen TOPMed |
|
|
CA402082710 rs1177554169 |
146 | V>G | No |
ClinGen gnomAD |
|
|
CA8919810 rs770882337 |
146 | V>M | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 147 | N>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA297155840 rs140777456 |
150 | M>T | No |
ClinGen ESP |
|
|
rs1164005657 CA402082732 |
150 | M>V | No |
ClinGen gnomAD |
|
|
CA297155844 rs966116549 |
152 | L>R | No |
ClinGen Ensembl |
|
|
CA8919813 rs745531655 |
153 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA8919814 rs769367107 |
156 | S>P | No |
ClinGen ExAC gnomAD |
|
|
CA402082799 rs1263890084 |
159 | D>G | No |
ClinGen TOPMed |
|
|
rs774932796 CA8919815 |
161 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8919817 rs764553661 |
162 | S>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1308578495 CA402082818 |
162 | S>N | No |
ClinGen TOPMed |
|
|
rs1361424243 CA402082823 |
163 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1377455216 CA402082831 |
164 | C>S | No |
ClinGen gnomAD |
|
|
CA8919819 rs376506423 |
166 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376506423 CA297155870 |
166 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs150102935 CA8919820 |
167 | G>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs750584363 CA8919822 |
169 | F>S | No |
ClinGen ExAC gnomAD |
|
|
CA8919823 rs756333613 |
170 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402082885 rs1599781160 |
172 | W>G | No |
ClinGen Ensembl |
|
| TCGA novel | 174 | I>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA402082903 rs1182866234 |
174 | I>V | No |
ClinGen gnomAD |
|
|
CA297155893 rs866983669 |
176 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1365841742 CA402082927 |
178 | T>A | No |
ClinGen TOPMed |
|
|
rs539561152 CA8919826 |
178 | T>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1389020635 CA402082941 |
180 | F>S | No |
ClinGen gnomAD |
|
|
rs377649493 CA8919829 |
182 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs377649493 CA8919830 |
182 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs745515394 CA8919831 |
183 | F>I | No |
ClinGen ExAC gnomAD |
|
|
CA8919833 rs775040150 |
184 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA402082993 rs1362766012 |
188 | I>T | No |
ClinGen gnomAD |
|
|
rs138611957 CA8919835 |
189 | L>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs774668999 CA8919836 |
189 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402082997 rs1568099585 |
189 | L>V | No |
ClinGen Ensembl |
|
|
rs773632780 COSM987199 CA8919839 |
191 | A>T | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 191 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA402083014 rs1261809128 |
192 | Y>H | No |
ClinGen TOPMed |
|
|
CA297155936 rs771532637 |
194 | N>K | No |
ClinGen gnomAD |
|
|
CA297155939 rs907401824 |
195 | M>V | No |
ClinGen Ensembl |
|
| TCGA novel | 196 | N>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs760866060 CA402083061 |
198 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760866060 CA402083062 |
198 | Y>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760866060 CA8919840 |
198 | Y>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1257526905 CA402083077 |
200 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA8919843 rs754123121 CA8919842 |
200 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA402083096 rs1475473856 |
203 | K>* | No |
ClinGen gnomAD |
|
|
CA8919845 rs115230320 |
204 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA297155958 rs540401617 |
204 | R>H | No |
ClinGen gnomAD |
|
|
rs750289020 CA8919848 |
206 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8919847 VAR_033478 rs11662595 |
206 | H>R | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA297155967 rs866992205 |
206 | H>Y | No |
ClinGen gnomAD |
|
|
CA402083168 rs1488326922 |
213 | H>R | No |
ClinGen gnomAD |
|
|
CA8919849 rs755757125 |
214 | P>H | No |
ClinGen ExAC gnomAD |
|
|
rs1273203526 CA402083180 |
215 | G>E | No |
ClinGen gnomAD |
|
|
rs1432937492 CA402083177 |
215 | G>R | No |
ClinGen gnomAD |
|
|
CA297156012 rs892114598 |
219 | V>I | No |
ClinGen Ensembl |
|
|
CA8919851 rs748989538 |
221 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA8919853 rs778488149 |
224 | C>* | No |
ClinGen ExAC gnomAD |
|
|
rs748648984 CA8919854 |
226 | H>N | No |
ClinGen ExAC gnomAD |
|
|
CA8919856 rs773536345 |
226 | H>P | No |
ClinGen ExAC gnomAD |
|
|
rs748648984 CA8919855 |
226 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs760988839 CA8919857 |
228 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA402083280 rs1599781320 |
231 | R>S | No |
ClinGen Ensembl |
|
|
rs1272027539 CA402083297 |
234 | S>L | No |
ClinGen Ensembl |
|
|
CA8919862 rs577543077 |
236 | R>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1427146140 CA402083322 |
238 | L>P | No |
ClinGen TOPMed |
|
|
CA8919864 rs116360028 |
241 | S>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1405726479 CA402083353 |
243 | E>D | No |
ClinGen gnomAD |
|
|
rs779909323 CA8919867 |
243 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs1262732249 CA402083356 |
244 | V>F | No |
ClinGen TOPMed |
|
|
CA8919868 rs753364037 |
246 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8919870 rs754725501 |
251 | E>A | No |
ClinGen ExAC gnomAD |
|
|
rs778380714 CA8919871 |
252 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA402083407 rs1351309174 |
252 | R>K | No |
ClinGen gnomAD |
|
|
CA402083409 rs1351309174 |
252 | R>T | No |
ClinGen gnomAD |
|
|
rs1048981773 CA297156093 |
253 | Q>* | No |
ClinGen TOPMed |
|
|
CA402083437 rs1599781383 |
256 | K>R | No |
ClinGen Ensembl |
|
|
CA297156098 rs113494520 |
257 | S>G | No |
ClinGen gnomAD |
|
|
rs1287055396 CA402083443 |
257 | S>N | No |
ClinGen gnomAD |
|
|
rs771602529 CA8919874 |
260 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA8919872 rs747705828 |
260 | M>V | No |
ClinGen ExAC gnomAD |
|
|
CA8919875 rs575538185 |
261 | F>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8919876 rs376308497 |
262 | S>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA402083485 rs1265584652 |
263 | S>* | No |
ClinGen TOPMed |
|
| TCGA novel | 264 | R>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs201245563 CA8919878 |
264 | R>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA8919880 rs777124514 |
267 | M>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777124514 CA8919879 |
267 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402083521 rs770107394 |
268 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402083518 rs1471410364 |
268 | N>S | No |
ClinGen gnomAD |
|
|
rs775677397 CA8919882 |
269 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1599781415 CA402083529 |
270 | N>D | No |
ClinGen Ensembl |
|
|
CA8919883 rs763083138 |
271 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402083544 rs1165608587 |
272 | I>V | No |
ClinGen gnomAD |
|
|
COSM74946 rs889005723 CA297156128 |
273 | A>S | ovary Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
| TCGA novel | 275 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 276 | M>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8919884 rs764288864 |
276 | M>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402083572 rs764288864 |
276 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 276 | M>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs867641946 CA297156148 |
280 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs1338689960 CA402083608 |
281 | Q>H | No |
ClinGen TOPMed |
|
|
rs760664429 CA8919888 |
282 | S>* | No |
ClinGen ExAC TOPMed |
|
|
rs773223791 CA8919887 |
282 | S>P | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 283 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8919889 rs58154316 |
284 | S>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs764830115 CA8919892 |
288 | H>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8919893 rs752369810 |
289 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs866575154 CA297156195 |
291 | E>* | No |
ClinGen Ensembl |
|
|
rs1194888510 CA402083692 |
294 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
rs777272194 CA8919895 |
297 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs1439952650 CA402083708 |
297 | R>I | No |
ClinGen gnomAD |
|
|
CA402083710 CA402083709 rs1185919741 |
297 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
CA8919897 rs757843291 |
300 | R>I | No |
ClinGen ExAC gnomAD |
|
|
CA8919899 rs746287648 |
304 | S>P | No |
ClinGen ExAC gnomAD |
|
|
CA8919900 rs770309894 |
306 | A>D | No |
ClinGen ExAC gnomAD |
|
|
rs1168734282 CA402083761 |
306 | A>T | No |
ClinGen gnomAD |
|
|
CA402083775 rs1411413924 |
308 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1341014410 CA402083782 |
309 | L>S | No |
ClinGen TOPMed |
|
|
CA402083788 rs1381928913 |
310 | G>E | No |
ClinGen gnomAD |
|
|
CA8919901 rs775802330 |
310 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 310 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8919902 rs545909864 |
312 | F>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs201686910 CA297156223 |
313 | A>S | No |
ClinGen 1000Genomes |
|
|
rs993563191 CA297156230 |
314 | V>G | No |
ClinGen Ensembl |
|
|
rs768786762 CA8919903 |
316 | W>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774636951 CA8919904 |
317 | A>P | No |
ClinGen ExAC gnomAD |
|
|
rs760514429 CA8919905 |
318 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs141897320 CA8919907 |
319 | Y>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8919910 rs139932565 |
327 | S>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA402083999 rs1185982064 |
330 | S>A | No |
ClinGen gnomAD |
|
|
CA402084057 rs116715978 |
334 | G>A | No |
ClinGen 1000Genomes ExAC TOPMed |
|
|
CA8919912 rs116715978 |
334 | G>V | No |
ClinGen 1000Genomes ExAC TOPMed |
|
|
rs1248799304 CA402084096 |
337 | S>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA8919913 rs751132957 |
338 | V>F | No |
ClinGen ExAC gnomAD |
|
|
CA8919914 rs757678921 |
339 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs1568100013 CA402084130 |
339 | W>C | No |
ClinGen Ensembl |
|
|
CA297156271 rs970330209 |
341 | R>G | No |
ClinGen TOPMed |
|
|
rs781692140 CA8919915 |
342 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA297156280 rs928808700 |
344 | F>V | No |
ClinGen TOPMed |
|
|
rs746380432 CA8919916 |
348 | W>* | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 348 | W>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA402084248 rs1338658780 |
350 | N>I | No |
ClinGen gnomAD |
|
|
CA402084247 rs1338658780 |
350 | N>S | No |
ClinGen gnomAD |
|
|
rs756485602 CA8919917 |
351 | S>A | No |
ClinGen ExAC gnomAD |
|
|
CA8919918 rs780567471 |
351 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749592787 CA8919919 |
355 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769056439 CA8919920 |
356 | L>R | No |
ClinGen ExAC gnomAD |
|
|
rs1264598611 CA402084291 |
357 | L>F | No |
ClinGen gnomAD |
|
|
CA8919921 rs778835181 |
357 | L>W | No |
ClinGen ExAC gnomAD |
|
|
CA8919924 rs776574126 |
361 | C>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8919925 rs759476238 |
362 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1205776417 CA402084330 |
363 | K>E | No |
ClinGen gnomAD |
|
|
rs769575154 CA8919926 |
364 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs149820026 CA8919927 COSM987200 |
364 | R>H | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA402084364 rs762574759 |
368 | A>P | No |
ClinGen ExAC gnomAD |
|
|
CA8919930 rs762574759 |
368 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs762574759 CA8919929 |
368 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA8919931 rs751206706 |
368 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA8919932 rs761334607 |
369 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA297156339 rs1043359718 |
369 | F>L | No |
ClinGen TOPMed |
|
|
rs901157949 CA297156343 |
372 | I>M | No |
ClinGen TOPMed |
|
|
CA8919933 rs766946164 |
373 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750872671 CA8919934 |
374 | C>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750872671 CA402084404 |
374 | C>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756749323 CA8919935 |
375 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA297156358 rs74604924 |
376 | K>* | No |
ClinGen Ensembl |
|
|
CA297156362 rs77041280 |
376 | K>I | No |
ClinGen Ensembl |
|
|
CA402084416 rs77041280 |
376 | K>T | No |
ClinGen Ensembl |
|
| TCGA novel | 377 | K>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA402084421 rs1422933507 |
377 | K>E | No |
ClinGen TOPMed |
|
|
CA402084426 rs146404280 |
377 | K>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs531238280 CA8919937 |
379 | P>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA402084436 rs1302177940 |
379 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1302177940 CA402084438 |
379 | P>T | No |
ClinGen TOPMed gnomAD |
|
|
CA297156390 rs550963133 |
381 | P>L | No |
ClinGen 1000Genomes gnomAD |
|
|
rs1316840229 COSM182700 CA402084469 |
384 | H>R | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs150959048 CA8919941 |
386 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA8919940 rs115905515 |
386 | R>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
No associated diseases with Q9H3N8
1 regional properties for Q9H3N8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 32 - 358 | IPR017452 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| dendrite | A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| synapse | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled acetylcholine receptor activity | Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
| G protein-coupled serotonin receptor activity | Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. |
| histamine receptor activity | Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. |
| neurotransmitter receptor activity | Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway | An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor, and ending with the regulation of a downstream cellular process. |
| chemical synaptic transmission | The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. |
| G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. |
| inflammatory response | The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. |
| positive regulation of cytosolic calcium ion concentration | Any process that increases the concentration of calcium ions in the cytosol. |
| regulation of MAPK cascade | Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade. |
126 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2YDN1 | GPR161 | G protein-coupled receptor 161 | Bos taurus (Bovine) | PR |
| Q0GBZ5 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Bos taurus (Bovine) | PR |
| Q17QD8 | GPR37L1 | G-protein coupled receptor 37-like 1 | Bos taurus (Bovine) | PR |
| Q8SPN1 | PROKR2 | Prokineticin receptor 2 | Bos taurus (Bovine) | PR |
| P46626 | ADRB3 | Beta-3 adrenergic receptor | Bos taurus (Bovine) | PR |
| O46639 | TRHR | Thyrotropin-releasing hormone receptor | Bos taurus (Bovine) | PR |
| Q8SPN2 | PROKR1 | Prokineticin receptor 1 | Bos taurus (Bovine) | PR |
| B9VR26 | CMLKR1 | Chemerin-like receptor 1 | Bos taurus (Bovine) | PR |
| P18130 | ADRA1A | Alpha-1A adrenergic receptor | Bos taurus (Bovine) | PR |
| B4XF06 | GPR39 | G-protein coupled receptor 39 | Bos taurus (Bovine) | PR |
| O18913 | OPN1LW | Long-wave-sensitive opsin 1 | Felis catus (Cat) (Felis silvestris catus) | PR |
| P28683 | PRA1 | Green-sensitive opsin | Gallus gallus (Chicken) | PR |
| Q9N298 | HTR1A | 5-hydroxytryptamine receptor 1A | Pan troglodytes (Chimpanzee) | PR |
| P08099 | Rh2 | Opsin Rh2 | Drosophila melanogaster (Fruit fly) | PR |
| P06002 | ninaE | Opsin Rh1 | Drosophila melanogaster (Fruit fly) | PR |
| Q4LBB9 | Octbeta2R | Octopamine receptor beta-2R | Drosophila melanogaster (Fruit fly) | PR |
| Q8NFJ6 | PROKR2 | Prokineticin receptor 2 | Homo sapiens (Human) | PR |
| Q13585 | GPR50 | Melatonin-related receptor | Homo sapiens (Human) | PR |
| Q9BZJ6 | GPR63 | Probable G-protein coupled receptor 63 | Homo sapiens (Human) | PR |
| P28336 | NMBR | Neuromedin-B receptor | Homo sapiens (Human) | PR |
| Q9Y5Y3 | GPR45 | Probable G-protein coupled receptor 45 | Homo sapiens (Human) | PR |
| P08913 | ADRA2A | Alpha-2A adrenergic receptor | Homo sapiens (Human) | PR |
| P41597 | CCR2 | C-C chemokine receptor type 2 | Homo sapiens (Human) | PR |
| P51681 | CCR5 | C-C chemokine receptor type 5 | Homo sapiens (Human) | PR |
| Q8TCW9 | PROKR1 | Prokineticin receptor 1 | Homo sapiens (Human) | PR |
| Q99788 | CMKLR1 | Chemerin-like receptor 1 | Homo sapiens (Human) | PR |
| P30559 | OXTR | Oxytocin receptor | Homo sapiens (Human) | PR |
| P32239 | CCKBR | Gastrin/cholecystokinin type B receptor | Homo sapiens (Human) | PR |
| O60883 | GPR37L1 | G-protein coupled receptor 37-like 1 | Homo sapiens (Human) | PR |
| Q8TDU9 | RXFP4 | Relaxin-3 receptor 2 | Homo sapiens (Human) | PR |
| P04000 | OPN1LW | Long-wave-sensitive opsin 1 | Homo sapiens (Human) | PR |
| Q6U736 | OPN5 | Opsin-5 | Homo sapiens (Human) | PR |
| P34972 | CNR2 | Cannabinoid receptor 2 | Homo sapiens (Human) | PR |
| P24530 | EDNRB | Endothelin receptor type B | Homo sapiens (Human) | PR |
| P35348 | ADRA1A | Alpha-1A adrenergic receptor | Homo sapiens (Human) | PR |
| Q6W5P4 | NPSR1 | Neuropeptide S receptor | Homo sapiens (Human) | PR |
| O43613 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Homo sapiens (Human) | PR |
| P61073 | CXCR4 | C-X-C chemokine receptor type 4 | Homo sapiens (Human) | PR |
| Q9BXC0 | HCAR1 | Hydroxycarboxylic acid receptor 1 | Homo sapiens (Human) | PR |
| P30556 | AGTR1 | Type-1 angiotensin II receptor | Homo sapiens (Human) | PR |
| Q15761 | NPY5R | Neuropeptide Y receptor type 5 | Homo sapiens (Human) | PR |
| Q8N6U8 | GPR161 | G-protein coupled receptor 161 | Homo sapiens (Human) | PR |
| Q6DWJ6 | GPR139 | Probable G-protein coupled receptor 139 | Homo sapiens (Human) | PR |
| P21462 | FPR1 | fMet-Leu-Phe receptor | Homo sapiens (Human) | PR |
| P35414 | APLNR | Apelin receptor | Homo sapiens (Human) | PR |
| P46091 | CMKLR2 | Chemerin-like receptor 2 | Homo sapiens (Human) | PR |
| P32745 | SSTR3 | Somatostatin receptor type 3 | Homo sapiens (Human) | PR |
| P41439 | FOLR3 | Folate receptor gamma | Homo sapiens (Human) | PR |
| P08908 | HTR1A | 5-hydroxytryptamine receptor 1A | Homo sapiens (Human) | PR |
| P08173 | CHRM4 | Muscarinic acetylcholine receptor M4 | Homo sapiens (Human) | PR |
| P11229 | CHRM1 | Muscarinic acetylcholine receptor M1 | Homo sapiens (Human) | PR |
| P08912 | CHRM5 | Muscarinic acetylcholine receptor M5 | Homo sapiens (Human) | PR |
| P08172 | CHRM2 | Muscarinic acetylcholine receptor M2 | Homo sapiens (Human) | PR |
| P20309 | CHRM3 | Muscarinic acetylcholine receptor M3 | Homo sapiens (Human) | PR |
| P35367 | HRH1 | Histamine H1 receptor | Homo sapiens (Human) | PR |
| P19973 | Lsp1 | Lymphocyte-specific protein 1 | Mus musculus (Mouse) | PR |
| O54799 | Nmbr | Neuromedin-B receptor | Mus musculus (Mouse) | PR |
| Q64264 | Htr1a | 5-hydroxytryptamine receptor 1A | Mus musculus (Mouse) | PR |
| P51675 | Ccr1 | C-C chemokine receptor type 1 | Mus musculus (Mouse) | PR |
| Q5U431 | Gpr39 | G-protein coupled receptor 39 | Mus musculus (Mouse) | PR |
| Q99JG2 | Gpr37l1 | G-protein coupled receptor 37-like 1 | Mus musculus (Mouse) | PR |
| P97295 | Npy2r | Neuropeptide Y receptor type 2 | Mus musculus (Mouse) | PR |
| O08786 | Cckar | Cholecystokinin receptor type A | Mus musculus (Mouse) | PR |
| P56481 | Cckbr | Gastrin/cholecystokinin type B receptor | Mus musculus (Mouse) | PR |
| P30731 | Gpr83 | G-protein coupled receptor 83 | Mus musculus (Mouse) | PR |
| P97468 | Cmklr1 | Chemerin-like receptor 1 | Mus musculus (Mouse) | PR |
| P21761 | Trhr | Thyrotropin-releasing hormone receptor | Mus musculus (Mouse) | PR |
| Q5QD16 | Taar3 | Trace amine-associated receptor 3 | Mus musculus (Mouse) | PR |
| P97292 | Hrh2 | Histamine H2 receptor | Mus musculus (Mouse) | PR |
| Q9EQQ3 | Gpr63 | Probable G-protein coupled receptor 63 | Mus musculus (Mouse) | PR |
| Q924H0 | Npffr2 | Neuropeptide FF receptor 2 | Mus musculus (Mouse) | PR |
| P34971 | Adrb1 | Beta-1 adrenergic receptor | Mus musculus (Mouse) | PR |
| O88416 | Gpr33 | Probable G-protein coupled receptor 33 | Mus musculus (Mouse) | PR |
| Q8K087 | Cmklr2 | Chemerin-like receptor 2 | Mus musculus (Mouse) | PR |
| P70658 | Cxcr4 | C-X-C chemokine receptor type 4 | Mus musculus (Mouse) | PR |
| Q9WV08 | Aplnr | Apelin receptor | Mus musculus (Mouse) | PR |
| P97718 | Adra1a | Alpha-1A adrenergic receptor | Mus musculus (Mouse) | PR |
| Q8BZP8 | Npsr1 | Neuropeptide S receptor | Mus musculus (Mouse) | PR |
| Q8K458 | Prokr2 | Prokineticin receptor 2 | Mus musculus (Mouse) | PR |
| P58308 | Hcrtr2 | Orexin receptor type 2 | Mus musculus (Mouse) | PR |
| Q7TQP3 | Gpr119 | Glucose-dependent insulinotropic receptor | Mus musculus (Mouse) | PR |
| Q8BGE9 | Rxfp3 | Relaxin-3 receptor 1 | Mus musculus (Mouse) | PR |
| Q6VZZ7 | Opn5 | Opsin-5 | Mus musculus (Mouse) | PR |
| Q8CIM5 | Gpr84 | G-protein coupled receptor 84 | Mus musculus (Mouse) | PR |
| P25962 | Adrb3 | Beta-3 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q80UC8 | Gpr139 | Probable G-protein coupled receptor 139 | Mus musculus (Mouse) | PR |
| P0C5I1 | Gpr25 | Probable G-protein coupled receptor 25 | Mus musculus (Mouse) | PR |
| P47936 | Cnr2 | Cannabinoid receptor 2 | Mus musculus (Mouse) | PR |
| Q5QD13 | Taar6 | Trace amine-associated receptor 6 | Mus musculus (Mouse) | PR |
| P35846 | Folr1 | Folate receptor alpha | Mus musculus (Mouse) | PR |
| P58307 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Mus musculus (Mouse) | PR |
| Q8C131 | Hcar1 | Hydroxycarboxylic acid receptor 1 | Mus musculus (Mouse) | PR |
| Q9EQQ4 | Gpr45 | Probable G-protein coupled receptor 45 | Mus musculus (Mouse) | PR |
| B2RPY5 | Gpr161 | G-protein coupled receptor 161 | Mus musculus (Mouse) | PR |
| Q91ZY2 | Hrh4 | Histamine H4 receptor | Mus musculus (Mouse) | PR |
| Q764M9 | CXCR4 | C-X-C chemokine receptor type 4 | Sus scrofa (Pig) | PR |
| Q9EQD2 | Npffr2 | Neuropeptide FF receptor 2 | Rattus norvegicus (Rat) | PR |
| O08565 | Cxcr4 | C-X-C chemokine receptor type 4 | Rattus norvegicus (Rat) | PR |
| Q01717 | Trhr | Thyrotropin-releasing hormone receptor | Rattus norvegicus (Rat) | PR |
| P30936 | Sstr3 | Somatostatin receptor type 3 | Rattus norvegicus (Rat) | PR |
| Q9JHG3 | Aplnr | Apelin receptor | Rattus norvegicus (Rat) | PR |
| P43140 | Adra1a | Alpha-1A adrenergic receptor | Rattus norvegicus (Rat) | PR |
| P19327 | Htr1a | 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Rat) | PR |
| P56719 | Hcrtr2 | Orexin receptor type 2 | Rattus norvegicus (Rat) | PR |
| P28564 | Htr1b | 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Rat) | PR |
| P56718 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Rattus norvegicus (Rat) | PR |
| P28647 | Adora3 | Adenosine receptor A3 | Rattus norvegicus (Rat) | PR |
| P25102 | Hrh2 | Histamine H2 receptor | Rattus norvegicus (Rat) | PR |
| P23944 | Adra1d | Alpha-1D adrenergic receptor | Rattus norvegicus (Rat) | PR |
| Q8R415 | Prokr2 | Prokineticin receptor 2 | Rattus norvegicus (Rat) | PR |
| Q5QD24 | Taar3 | Trace amine-associated receptor 3 | Rattus norvegicus (Rat) | PR |
| P0C0W8 | Gpr139 | Probable G-protein coupled receptor 139 | Rattus norvegicus (Rat) | PR |
| P35370 | Oprl1 | Nociceptin receptor | Rattus norvegicus (Rat) | PR |
| P46090 | Cmklr2 | Chemerin-like receptor 2 | Rattus norvegicus (Rat) | PR |
| O97664 | CMKLR2 | Chemerin-like receptor 2 | Macaca mulatta (Rhesus macaque) | PR |
| O97666 | APLNR | Apelin receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q56H79 | NPSR1 | Neuropeptide S receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q18904 | npr-8 | Probable G-protein coupled receptor npr-8 | Caenorhabditis elegans | PR |
| Q09388 | gar-2 | Muscarinic acetylcholine receptor gar-2 | Caenorhabditis elegans | PR |
| Q9U7D5 | gar-3 | Muscarinic acetylcholine receptor gar-3 | Caenorhabditis elegans | PR |
| B3DM66 | gpr161 | G-protein coupled receptor 161 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q9W6A6 | opn1mw4 | Green-sensitive opsin-4 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q9W6A5 | opn1mw1 | Green-sensitive opsin-1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYM7 | opn1mw3 | Green-sensitive opsin-3 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYN0 | opn1lw2 | Red-sensitive opsin-2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q90X46 | gpr161 | G-protein coupled receptor 161 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPDTNSTINL | SLSTRVTLAF | FMSLVAFAIM | LGNALVILAF | VVDKNLRHRS | SYFFLNLAIS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DFFVGVISIP | LYIPHTLFEW | DFGKEICVFW | LTTDYLLCTA | SVYNIVLISY | DRYLSVSNAV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SYRTQHTGVL | KIVTLMVAVW | VLAFLVNGPM | ILVSESWKDE | GSECEPGFFS | EWYILAITSF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LEFVIPVILV | AYFNMNIYWS | LWKRDHLSRC | QSHPGLTAVS | SNICGHSFRG | RLSSRRSLSA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| STEVPASFHS | ERQRRKSSLM | FSSRTKMNSN | TIASKMGSFS | QSDSVALHQR | EHVELLRARR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LAKSLAILLG | VFAVCWAPYS | LFTIVLSFYS | SATGPKSVWY | RIAFWLQWFN | SFVNPLLYPL |
| 370 | 380 | ||||
| CHKRFQKAFL | KIFCIKKQPL | PSQHSRSVSS |