Q99788
PR
Gene name |
CMKLR1 |
Protein name |
Chemerin-like receptor 1 |
Names |
Chemokine-like receptor 1, G-protein coupled receptor ChemR23, G-protein coupled receptor DEZ |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:1240 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for Q99788
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7YKD | EM | 281 A | A | 1-373 | PDB |
| 8SG1 | EM | 294 A | R | 36-327 | PDB |
| AF-Q99788-F1 | Predicted | AlphaFoldDB |
329 variants for Q99788
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA386419474 rs772375747 |
4 | E>D | No |
ClinGen ExAC gnomAD |
|
|
rs200344687 CA243270205 |
6 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
rs200344687 CA386419461 |
6 | E>V | No |
ClinGen TOPMed gnomAD |
|
|
CA6767315 rs376509653 |
7 | D>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 7 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs202234426 CA6767314 |
8 | Y>S | No |
ClinGen ExAC gnomAD |
|
|
rs755870319 CA6767313 |
9 | N>H | No |
ClinGen ExAC gnomAD |
|
|
rs913869104 COSM934560 CA243270176 |
15 | G>S | endometrium [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
rs754946817 CA6767310 |
18 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751158064 CA6767309 |
19 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs992175629 CA243270135 |
22 | L>S | No |
ClinGen Ensembl |
|
|
rs537099458 CA6767308 |
25 | I>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1287310083 CA386419321 |
27 | V>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA243270127 rs942145947 |
29 | E>K | No |
ClinGen TOPMed |
|
|
rs568799764 CA6767307 |
32 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs764876734 CA6767305 |
33 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs369981839 CA6767306 |
33 | P>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA386419261 rs1480380452 |
36 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA6767304 rs199548216 |
37 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1222269580 CA386419253 |
37 | R>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
TCGA novel CA6767303 rs776930995 |
37 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC gnomAD NCI-TCGA |
| TCGA novel | 40 | R>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6767300 rs775702945 |
41 | I>F | No |
ClinGen ExAC gnomAD |
|
|
CA386419229 rs1308782681 |
41 | I>T | No |
ClinGen gnomAD |
|
|
CA386419213 rs761155992 |
44 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761155992 CA6767299 |
44 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779039224 CA243269989 |
45 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA6767297 rs779039224 |
45 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs748007872 CA6767295 |
46 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs1003939483 CA243269941 |
49 | I>V | No |
ClinGen Ensembl |
|
|
rs150895979 CA6767293 |
50 | V>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs997852514 CA243269931 |
51 | C>S | No |
ClinGen gnomAD |
|
|
CA386419169 rs997852514 |
51 | C>Y | No |
ClinGen gnomAD |
|
|
CA386419158 rs751530283 |
52 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs779984645 CA6767291 |
53 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764818755 CA6767288 CA6767289 |
54 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6767287 rs756878978 |
56 | L>P | No |
ClinGen ExAC gnomAD |
|
|
COSM1470507 CA6767286 rs754239043 |
57 | G>D | Variant assessed as Somatic; 0.0 impact. prostate [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA386419137 rs1212833115 |
57 | G>S | No |
ClinGen gnomAD |
|
|
rs764435421 CA6767285 |
59 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761225810 CA6767284 |
60 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA386419114 rs1593156128 |
61 | V>M | No |
ClinGen Ensembl |
|
|
rs141421422 CA6767281 |
62 | I>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs775871090 CA6767283 |
62 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1336388364 CA386419100 |
63 | I>T | No |
ClinGen TOPMed |
|
|
rs192034694 CA6767280 |
64 | I>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1479361564 CA386419088 |
65 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA386419067 rs1157226785 |
68 | K>R | No |
ClinGen gnomAD |
|
|
rs202104056 CA6767278 |
69 | M>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA386419055 rs1378443985 |
70 | K>* | No |
ClinGen gnomAD |
|
|
CA386419054 rs1378443985 |
70 | K>E | No |
ClinGen gnomAD |
|
|
CA386419048 rs1195509857 |
70 | K>N | No |
ClinGen gnomAD |
|
| TCGA novel | 71 | K>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs749519428 CA6767276 |
73 | V>A | No |
ClinGen ExAC |
|
|
rs1263522337 CA386419013 CA386419014 |
75 | M>I | No |
ClinGen gnomAD |
|
|
CA386419018 rs1447335825 |
75 | M>K | No |
ClinGen gnomAD |
|
|
rs768584661 CA6767274 |
75 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746753225 CA6767273 |
78 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs779887002 CA6767272 |
82 | A>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM200599 rs945414719 CA243269765 |
82 | A>T | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
|
CA386418959 rs1280682418 |
84 | A>T | No |
ClinGen gnomAD |
|
|
rs758307028 CA6767271 |
85 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA386418914 rs1262166778 |
90 | V>A | No |
ClinGen TOPMed |
|
|
rs1303270427 CA386418919 |
90 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA386418909 rs1593155975 |
91 | F>S | No |
ClinGen Ensembl |
|
|
CA6767268 rs367921179 |
92 | L>V | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1316611502 CA386418895 |
93 | P>L | No |
ClinGen gnomAD |
|
|
CA6767267 rs753472328 |
94 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs1382018776 CA386418893 |
94 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs756505533 CA6767265 |
95 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA386418886 rs1432921366 |
95 | H>Y | No |
ClinGen gnomAD |
|
|
CA386418873 rs1593155928 |
97 | T>P | No |
ClinGen Ensembl |
|
|
CA919169838 rs1593155917 |
99 | A>M* | No |
ClinGen Ensembl |
|
|
CA6767262 rs370635582 |
100 | A>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
COSM1561866 CA6767263 rs370635582 |
100 | A>T | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1374727525 CA386418846 |
101 | M>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA386418849 rs1472833263 |
101 | M>V | No |
ClinGen TOPMed |
|
| TCGA novel | 101 | M>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1190751376 CA386418839 |
102 | D>Y | No |
ClinGen gnomAD |
|
|
CA386418829 rs1427490831 |
103 | Y>C | No |
ClinGen TOPMed |
|
|
rs1446270903 CA386418823 |
104 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA243269723 rs926636183 |
108 | G>R | No |
ClinGen gnomAD |
|
|
rs200117272 CA6767260 |
109 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA386418772 rs1484502069 |
111 | M>I | No |
ClinGen gnomAD |
|
|
CA243269709 rs1055891109 |
111 | M>V | No |
ClinGen TOPMed |
|
|
CA386418760 rs1278934385 |
113 | K>E | No |
ClinGen gnomAD |
|
|
rs937791898 CA243269690 |
114 | I>T | No |
ClinGen TOPMed |
|
|
rs1214663127 CA386418736 |
116 | N>T | No |
ClinGen gnomAD |
|
|
rs941609045 CA243269675 |
118 | L>F | No |
ClinGen Ensembl |
|
|
CA386418717 rs1332043542 |
119 | L>F | No |
ClinGen gnomAD |
|
|
rs1440834173 CA386418712 |
120 | I>V | No |
ClinGen gnomAD |
|
|
rs763068906 CA6767258 |
122 | N>D | No |
ClinGen ExAC gnomAD |
|
|
rs910010563 CA243269657 |
122 | N>I | No |
ClinGen gnomAD |
|
|
CA6767256 rs770099716 CA386418687 |
123 | M>I | No |
ClinGen ExAC gnomAD |
|
|
rs773573813 CA6767257 |
123 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746801664 CA6767255 |
124 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA243269602 rs906374473 |
125 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs370619531 CA243269589 |
126 | S>N | No |
ClinGen Ensembl |
|
|
CA6767254 rs771942258 |
126 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA6767252 rs374487323 |
127 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 128 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA243269573 rs879355530 |
131 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs879355530 CA243269561 |
131 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
rs778450275 CA6767251 |
132 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA243269510 rs866870584 |
133 | I>T | No |
ClinGen Ensembl |
|
|
rs756768774 CA6767250 |
133 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs575229573 CA243269495 |
135 | S>F | No |
ClinGen Ensembl |
|
|
CA386418620 rs1189822603 |
135 | S>P | No |
ClinGen gnomAD |
|
|
rs748726343 CA6767249 |
136 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA6767248 rs148287464 |
137 | R>C | Variant assessed as Somatic; 0.0001391 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs201652470 CA6767247 |
137 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs61740671 CA6767246 |
142 | L>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA6767245 rs781618608 |
142 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA6767242 rs764278648 |
144 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs752122136 CA6767243 |
144 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA243269354 rs936383277 COSM3359515 |
145 | V>I | kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs750481072 CA6767240 |
146 | W>* | No |
ClinGen ExAC gnomAD |
|
|
CA386418556 rs750481072 |
146 | W>S | No |
ClinGen ExAC gnomAD |
|
|
CA386418530 rs1178655930 |
149 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
CA6767238 rs762062468 |
150 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM691389 CA6767237 rs775214476 |
151 | R>C | lung large_intestine breast [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
COSM934556 CA6767236 rs771883601 |
151 | R>H | Variant assessed as Somatic; 0.0002319 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs775214476 CA386418522 |
151 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774689822 CA6767234 |
153 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs146650378 CA6767233 COSM3980735 |
154 | R>C | ovary [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA6767232 rs749502814 |
154 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA386418493 rs1360620335 |
156 | A>D | No |
ClinGen TOPMed |
|
|
CA6767230 rs769403375 |
158 | M>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA6767231 rs777235887 |
158 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1356049422 CA386418472 |
159 | A>V | No |
ClinGen gnomAD |
|
|
CA6767229 rs747824224 |
160 | C>F | No |
ClinGen ExAC gnomAD |
|
|
CA386418469 rs1469247569 |
160 | C>R | No |
ClinGen gnomAD |
|
|
rs1212192795 CA386418463 |
160 | C>W | No |
ClinGen TOPMed gnomAD |
|
|
CA386418451 rs1334661860 |
162 | V>F | No |
ClinGen gnomAD |
|
|
CA6767227 rs780132798 |
163 | I>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780132798 CA6767228 |
163 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA386418439 rs1221387015 |
164 | W>* | No |
ClinGen TOPMed |
|
| TCGA novel | 166 | L>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6767226 rs116316255 |
168 | F>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA6767225 rs780728645 |
170 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA386418382 rs1278972829 |
172 | S>F | No |
ClinGen gnomAD |
|
|
rs758950696 CA6767224 |
173 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs750569132 CA6767223 |
175 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs905167425 CA243269191 |
176 | V>I | No |
ClinGen gnomAD |
|
|
CA243269175 rs564425356 |
177 | F>L | No |
ClinGen Ensembl |
|
|
CA6767220 rs754100800 |
178 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA6767221 COSM94083 rs374245414 |
178 | R>W | lung [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA6767218 rs759403635 |
179 | D>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA243269160 rs553674701 |
180 | T>A | No |
ClinGen Ensembl |
|
| TCGA novel | 182 | N>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs941556680 CA243269156 |
182 | N>K | No |
ClinGen Ensembl |
|
|
CA6767216 rs185900141 |
187 | I>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA243269155 rs1016965854 |
187 | I>T | No |
ClinGen TOPMed |
|
|
rs762875647 CA6767215 |
188 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 189 | C>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6767214 rs143907187 |
191 | N>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA386418269 rs143907187 |
191 | N>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs199755416 CA6767213 |
193 | F>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA6767212 rs747547528 |
194 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs201961201 CA6767211 |
194 | S>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA386418234 rs1350208182 |
196 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA243269070 rs963781999 |
197 | T>A | No |
ClinGen gnomAD |
|
|
rs780534690 CA6767208 |
198 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1366851779 CA386418220 |
199 | G>E | No |
ClinGen gnomAD |
|
|
rs759038574 CA6767207 |
200 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1445498106 CA386418211 |
201 | S>P | No |
ClinGen TOPMed |
|
|
rs374433270 CA6767205 |
202 | S>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA386418205 rs1248704579 |
202 | S>P | No |
ClinGen TOPMed |
|
|
COSM1358504 CA386418199 rs1396320396 |
203 | W>* | large_intestine [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs182243804 CA6767203 |
203 | W>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1182252314 CA386418183 |
205 | T>I | No |
ClinGen TOPMed |
|
|
CA386418181 rs1433053996 |
206 | H>N | No |
ClinGen TOPMed gnomAD |
|
|
CA386418178 rs369780770 |
206 | H>P | No |
ClinGen ESP ExAC gnomAD |
|
|
CA6767202 rs369780770 |
206 | H>R | No |
ClinGen ESP ExAC gnomAD |
|
|
rs375866656 CA6767200 |
207 | S>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs375866656 CA6767201 |
207 | S>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA386418158 rs1158358718 |
209 | M>T | No |
ClinGen TOPMed |
|
|
rs766152449 CA6767199 |
210 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA243268962 rs751960797 |
211 | P>R | No |
ClinGen TOPMed |
|
|
CA386417562 rs1241722837 |
211 | P>S | No |
ClinGen gnomAD |
|
|
CA6767197 rs773139615 |
213 | G>E | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 213 | G>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs200130577 CA6767195 |
214 | Y>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA6767194 rs190075450 |
215 | S>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA386417467 rs1216082084 |
216 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs768395188 CA6767193 |
216 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1342225025 COSM546251 CA386417450 |
217 | H>L | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
rs78384048 CA6767192 |
217 | H>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA386417457 rs1332059930 |
217 | H>Y | No |
ClinGen TOPMed |
|
|
CA243268911 rs111591814 |
219 | V>A | No |
ClinGen Ensembl |
|
|
rs1297383468 CA386417424 |
219 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
rs776053757 CA6767191 |
223 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA386417368 rs776053757 |
223 | T>P | No |
ClinGen ExAC gnomAD |
|
|
CA6767190 rs200653739 |
224 | R>C | Variant assessed as Somatic; 4.644e-05 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
|
CA6767189 rs746165927 |
224 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6767188 rs779501834 |
225 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA386417277 rs1427078083 |
228 | G>V | No |
ClinGen gnomAD |
|
|
CA6767187 rs749428744 |
230 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749428744 CA6767186 |
230 | L>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777714160 CA6767185 |
232 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1375915997 CA386417180 |
235 | I>M | No |
ClinGen gnomAD |
|
|
CA386417183 rs200591654 |
235 | I>N | No |
ClinGen 1000Genomes TOPMed |
|
|
CA243268815 rs200591654 |
235 | I>S | No |
ClinGen 1000Genomes TOPMed |
|
|
rs1201875066 CA386417171 |
236 | I>T | No |
ClinGen TOPMed |
|
|
CA386417164 rs1258792763 |
237 | T>A | No |
ClinGen TOPMed |
|
|
COSM934555 rs767660173 CA6767181 |
238 | A>T | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1305716929 CA386417134 |
239 | C>G | No |
ClinGen gnomAD |
|
|
CA6767180 rs758221621 |
240 | Y>D | No |
ClinGen ExAC |
|
|
CA386417119 rs1593155300 |
240 | Y>S | No |
ClinGen Ensembl |
|
|
CA243268786 rs936309837 |
242 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA386417086 rs1291121093 |
242 | T>N | No |
ClinGen gnomAD |
|
|
CA386417090 rs936309837 |
242 | T>P | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 243 | I>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 243 | I>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs761623535 COSM934554 CA6767177 |
244 | V>M | endometrium Variant assessed as Somatic; 0.0004181 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA386416983 rs1183875678 |
248 | Q>K | No |
ClinGen TOPMed |
|
|
COSM3788104 rs201809939 CA6767175 |
249 | R>C | pancreas [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA6767174 rs760204829 |
249 | R>H | Variant assessed as Somatic; 4.646e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA6767173 COSM94082 rs775282959 |
251 | R>C | pancreas [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs750358962 CA6767171 COSM279950 |
251 | R>H | large_intestine haematopoietic_and_lymphoid_tissue [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA6767172 rs750358962 |
251 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1419924322 CA386416887 |
253 | A>V | No |
ClinGen gnomAD |
|
| TCGA novel | 254 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6767170 rs774554343 |
255 | T>A | No |
ClinGen ExAC gnomAD |
|
|
COSM934553 rs771537993 CA6767169 |
256 | K>N | endometrium [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
| TCGA novel | 258 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1566016788 CA386416744 |
262 | I>T | No |
ClinGen Ensembl |
|
|
rs1270850682 CA386416669 |
267 | I>F | No |
ClinGen gnomAD |
|
|
rs1593155187 CA386416646 |
268 | T>I | No |
ClinGen Ensembl |
|
|
rs769868823 CA6767165 |
270 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA6767164 rs748186818 |
271 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA386416508 rs1326297827 |
275 | P>H | No |
ClinGen gnomAD |
|
|
rs1293908475 CA386416443 |
278 | T>I | No |
ClinGen gnomAD |
|
|
rs1231089528 CA386416421 |
280 | N>H | No |
ClinGen TOPMed |
|
|
CA386416412 rs1392682031 |
280 | N>K | No |
ClinGen gnomAD |
|
| TCGA novel | 283 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6767160 rs755172620 |
283 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA6767159 rs750271226 |
284 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs77655238 CA243268613 |
285 | H>P | No |
ClinGen Ensembl |
|
| TCGA novel | 285 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1566016715 CA386416267 |
288 | A>V | No |
ClinGen Ensembl |
|
|
CA6767157 RCV000879567 rs116531815 |
289 | M>I | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA6767158 rs778567159 |
289 | M>V | No |
ClinGen ExAC gnomAD |
|
|
COSM94081 rs753731758 CA6767156 |
290 | P>T | lung [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs374395148 CA6767155 |
291 | G>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA386416242 rs1593155108 |
291 | G>S | No |
ClinGen Ensembl |
|
|
rs1271570277 CA386416232 |
292 | S>T | No |
ClinGen TOPMed |
|
|
CA386416221 rs1469791673 |
293 | V>A | No |
ClinGen gnomAD |
|
|
rs61740670 CA243268557 |
295 | S>G | No |
ClinGen TOPMed gnomAD |
|
|
CA243268515 rs760294634 |
297 | G>V | No |
ClinGen Ensembl |
|
|
CA386416171 rs1350861905 CA386416169 |
298 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA6767151 rs767325154 |
300 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs774839942 CA6767148 |
302 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1002902072 CA243268455 |
305 | A>P | No |
ClinGen TOPMed |
|
|
CA6767147 rs201704022 |
306 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 307 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1167238839 CA386416094 |
307 | A>T | No |
ClinGen TOPMed |
|
|
CA386416062 rs1323228678 |
309 | S>T | No |
ClinGen gnomAD |
|
|
rs1387396471 CA386416034 |
311 | M>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs763314363 CA6767146 |
311 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1287383967 CA386416026 |
312 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1419140209 CA386416009 |
315 | L>V | No |
ClinGen gnomAD |
|
|
rs1364798937 CA386416001 |
316 | Y>C | No |
ClinGen TOPMed |
|
| TCGA novel | 318 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1175627067 CA386415983 |
319 | M>L | No |
ClinGen TOPMed gnomAD |
|
|
rs773740776 CA6767145 |
319 | M>T | No |
ClinGen ExAC |
|
|
CA386415982 rs1175627067 |
319 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
CA243268444 rs1020829003 |
322 | D>N | No |
ClinGen TOPMed |
|
|
rs1375868473 CA386415957 |
322 | D>V | No |
ClinGen gnomAD |
|
|
CA386415947 rs1197902833 |
323 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
CA6767144 rs770237063 |
324 | K>R | No |
ClinGen ExAC gnomAD |
|
|
rs910964191 CA243268436 |
328 | V>L | No |
ClinGen gnomAD |
|
|
rs910964191 CA386415915 |
328 | V>M | No |
ClinGen gnomAD |
|
|
CA6767141 rs781219350 |
332 | S>A | No |
ClinGen ExAC gnomAD |
|
|
CA6767140 rs370160040 |
333 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA6767139 rs201296420 |
333 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 333 | R>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386415885 rs370160040 |
333 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs780264082 CA6767138 |
335 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA386415874 rs1343488230 |
335 | V>F | No |
ClinGen gnomAD |
|
| TCGA novel | 335 | V>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1228583546 CA386415867 |
336 | N>S | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 338 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1478665448 CA386415845 |
339 | S>R | No |
ClinGen TOPMed gnomAD |
|
|
CA386415833 rs1399580085 |
341 | D>A | No |
ClinGen gnomAD |
|
| TCGA novel | 342 | T>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386415819 rs777870525 |
343 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA6767135 rs777870525 |
343 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs200353879 CA243268365 |
345 | S>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA6767134 rs200353879 |
345 | S>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1566016532 CA386415807 |
345 | S>P | No |
ClinGen Ensembl |
|
|
rs1399966451 CA386415805 |
346 | S>T | No |
ClinGen gnomAD |
|
| TCGA novel | 347 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6767133 rs752292616 |
347 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
rs767125122 CA6767132 |
347 | Y>S | No |
ClinGen ExAC gnomAD |
|
|
CA243268337 rs1050038676 |
348 | P>L | No |
ClinGen TOPMed |
|
|
CA386415791 rs1187496156 |
348 | P>S | No |
ClinGen gnomAD |
|
| TCGA novel | 349 | S>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs933026249 CA243268321 |
349 | S>R | No |
ClinGen TOPMed |
|
|
rs200431477 CA386415777 |
350 | H>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA6767130 rs200431477 |
350 | H>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA6767129 rs766015264 |
352 | S>G | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 352 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386415761 rs1212388569 |
352 | S>R | No |
ClinGen gnomAD |
|
|
CA6767128 rs763248802 |
354 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1384347378 CA386415750 |
354 | T>N | No |
ClinGen TOPMed |
|
|
rs200703499 CA243268281 |
355 | K>* | No |
ClinGen Ensembl |
|
|
COSM3416437 rs773544935 CA6767127 |
355 | K>N | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs770326992 CA6767126 |
358 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762301757 CA6767125 |
359 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs1256496794 CA386415712 |
360 | N>D | No |
ClinGen gnomAD |
|
| TCGA novel | 360 | N>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 361 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA243268240 rs373370627 |
361 | E>K | No |
ClinGen Ensembl |
|
|
CA6767124 rs377656516 |
361 | E>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 362 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6767123 rs373997559 |
363 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs373997559 CA243268222 |
363 | T>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1035493055 CA243268219 |
364 | S>F | No |
ClinGen Ensembl |
|
|
rs1339903073 CA386415678 |
365 | M>I | No |
ClinGen gnomAD |
|
|
CA386415680 rs1367509958 |
365 | M>T | No |
ClinGen TOPMed |
|
|
CA6767121 rs370161103 |
365 | M>V | Variant assessed as Somatic; 4.646e-05 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
COSM1248498 rs1329645748 CA386415667 |
367 | E>Q | oesophagus [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs1410401682 CA386415650 |
369 | E>* | No |
ClinGen TOPMed gnomAD |
|
|
rs1410401682 CA386415652 |
369 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA6767117 rs756181043 |
371 | G>D | Variant assessed as Somatic; 9.355e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs149078040 CA6767118 |
371 | G>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA386415632 rs1292990117 |
372 | M>L | No |
ClinGen gnomAD |
|
|
CA6767116 rs748112149 |
374 | L>C | No |
ClinGen ExAC gnomAD |
No associated diseases with Q99788
1 regional properties for Q99788
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 63 - 358 | IPR017452 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| adipokinetic hormone binding | Binding to an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. |
| adipokinetic hormone receptor activity | Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. |
| chemokine receptor activity | Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. |
| complement receptor activity | Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
| G protein-coupled receptor activity | Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
| signaling receptor activity | Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. |
14 GO annotations of biological process
| Name | Definition |
|---|---|
| chemotaxis | The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). |
| complement receptor mediated signaling pathway | The series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway. |
| G protein-coupled receptor signaling pathway | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
| immune response | Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. |
| inflammatory response | The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. |
| negative regulation of interleukin-12 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production. |
| negative regulation of NF-kappaB transcription factor activity | Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB. |
| phospholipase C-activating G protein-coupled receptor signaling pathway | A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). |
| positive regulation of cold-induced thermogenesis | Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis. |
| positive regulation of cytosolic calcium ion concentration | Any process that increases the concentration of calcium ions in the cytosol. |
| positive regulation of fat cell differentiation | Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. |
| positive regulation of macrophage chemotaxis | Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. |
| regulation of calcium-mediated signaling | Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response. |
| skeletal system development | The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). |
119 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2YDN1 | GPR161 | G protein-coupled receptor 161 | Bos taurus (Bovine) | PR |
| Q0GBZ5 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Bos taurus (Bovine) | PR |
| Q17QD8 | GPR37L1 | G-protein coupled receptor 37-like 1 | Bos taurus (Bovine) | PR |
| Q8SPN1 | PROKR2 | Prokineticin receptor 2 | Bos taurus (Bovine) | PR |
| P46626 | ADRB3 | Beta-3 adrenergic receptor | Bos taurus (Bovine) | PR |
| O46639 | TRHR | Thyrotropin-releasing hormone receptor | Bos taurus (Bovine) | PR |
| Q8SPN2 | PROKR1 | Prokineticin receptor 1 | Bos taurus (Bovine) | PR |
| P18130 | ADRA1A | Alpha-1A adrenergic receptor | Bos taurus (Bovine) | PR |
| B4XF06 | GPR39 | G-protein coupled receptor 39 | Bos taurus (Bovine) | PR |
| B9VR26 | CMLKR1 | Chemerin-like receptor 1 | Bos taurus (Bovine) | PR |
| O18913 | OPN1LW | Long-wave-sensitive opsin 1 | Felis catus (Cat) (Felis silvestris catus) | PR |
| P28683 | PRA1 | Green-sensitive opsin | Gallus gallus (Chicken) | PR |
| Q9N298 | HTR1A | 5-hydroxytryptamine receptor 1A | Pan troglodytes (Chimpanzee) | PR |
| P08099 | Rh2 | Opsin Rh2 | Drosophila melanogaster (Fruit fly) | PR |
| P06002 | ninaE | Opsin Rh1 | Drosophila melanogaster (Fruit fly) | PR |
| Q4LBB9 | Octbeta2R | Octopamine receptor beta-2R | Drosophila melanogaster (Fruit fly) | PR |
| Q8NFJ6 | PROKR2 | Prokineticin receptor 2 | Homo sapiens (Human) | PR |
| Q13585 | GPR50 | Melatonin-related receptor | Homo sapiens (Human) | PR |
| Q9BZJ6 | GPR63 | Probable G-protein coupled receptor 63 | Homo sapiens (Human) | PR |
| Q9H3N8 | HRH4 | Histamine H4 receptor | Homo sapiens (Human) | PR |
| P28336 | NMBR | Neuromedin-B receptor | Homo sapiens (Human) | PR |
| Q9Y5Y3 | GPR45 | Probable G-protein coupled receptor 45 | Homo sapiens (Human) | PR |
| P08913 | ADRA2A | Alpha-2A adrenergic receptor | Homo sapiens (Human) | PR |
| P41597 | CCR2 | C-C chemokine receptor type 2 | Homo sapiens (Human) | PR |
| P51681 | CCR5 | C-C chemokine receptor type 5 | Homo sapiens (Human) | PR |
| Q8TCW9 | PROKR1 | Prokineticin receptor 1 | Homo sapiens (Human) | PR |
| P08908 | HTR1A | 5-hydroxytryptamine receptor 1A | Homo sapiens (Human) | PR |
| P30559 | OXTR | Oxytocin receptor | Homo sapiens (Human) | PR |
| P32239 | CCKBR | Gastrin/cholecystokinin type B receptor | Homo sapiens (Human) | PR |
| O60883 | GPR37L1 | G-protein coupled receptor 37-like 1 | Homo sapiens (Human) | PR |
| Q8TDU9 | RXFP4 | Relaxin-3 receptor 2 | Homo sapiens (Human) | PR |
| P04000 | OPN1LW | Long-wave-sensitive opsin 1 | Homo sapiens (Human) | PR |
| Q6U736 | OPN5 | Opsin-5 | Homo sapiens (Human) | PR |
| P34972 | CNR2 | Cannabinoid receptor 2 | Homo sapiens (Human) | PR |
| P24530 | EDNRB | Endothelin receptor type B | Homo sapiens (Human) | PR |
| P35348 | ADRA1A | Alpha-1A adrenergic receptor | Homo sapiens (Human) | PR |
| Q6W5P4 | NPSR1 | Neuropeptide S receptor | Homo sapiens (Human) | PR |
| O43613 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Homo sapiens (Human) | PR |
| P61073 | CXCR4 | C-X-C chemokine receptor type 4 | Homo sapiens (Human) | PR |
| Q9BXC0 | HCAR1 | Hydroxycarboxylic acid receptor 1 | Homo sapiens (Human) | PR |
| P30556 | AGTR1 | Type-1 angiotensin II receptor | Homo sapiens (Human) | PR |
| Q15761 | NPY5R | Neuropeptide Y receptor type 5 | Homo sapiens (Human) | PR |
| Q8N6U8 | GPR161 | G-protein coupled receptor 161 | Homo sapiens (Human) | PR |
| Q6DWJ6 | GPR139 | Probable G-protein coupled receptor 139 | Homo sapiens (Human) | PR |
| P35414 | APLNR | Apelin receptor | Homo sapiens (Human) | PR |
| P46091 | CMKLR2 | Chemerin-like receptor 2 | Homo sapiens (Human) | PR |
| P32745 | SSTR3 | Somatostatin receptor type 3 | Homo sapiens (Human) | PR |
| P41439 | FOLR3 | Folate receptor gamma | Homo sapiens (Human) | PR |
| P21462 | FPR1 | fMet-Leu-Phe receptor | Homo sapiens (Human) | PR |
| P19973 | Lsp1 | Lymphocyte-specific protein 1 | Mus musculus (Mouse) | PR |
| O54799 | Nmbr | Neuromedin-B receptor | Mus musculus (Mouse) | PR |
| Q64264 | Htr1a | 5-hydroxytryptamine receptor 1A | Mus musculus (Mouse) | PR |
| P51675 | Ccr1 | C-C chemokine receptor type 1 | Mus musculus (Mouse) | PR |
| Q5U431 | Gpr39 | G-protein coupled receptor 39 | Mus musculus (Mouse) | PR |
| Q99JG2 | Gpr37l1 | G-protein coupled receptor 37-like 1 | Mus musculus (Mouse) | PR |
| P97295 | Npy2r | Neuropeptide Y receptor type 2 | Mus musculus (Mouse) | PR |
| O08786 | Cckar | Cholecystokinin receptor type A | Mus musculus (Mouse) | PR |
| P56481 | Cckbr | Gastrin/cholecystokinin type B receptor | Mus musculus (Mouse) | PR |
| P30731 | Gpr83 | G-protein coupled receptor 83 | Mus musculus (Mouse) | PR |
| P21761 | Trhr | Thyrotropin-releasing hormone receptor | Mus musculus (Mouse) | PR |
| Q5QD16 | Taar3 | Trace amine-associated receptor 3 | Mus musculus (Mouse) | PR |
| P97292 | Hrh2 | Histamine H2 receptor | Mus musculus (Mouse) | PR |
| Q9EQQ3 | Gpr63 | Probable G-protein coupled receptor 63 | Mus musculus (Mouse) | PR |
| Q924H0 | Npffr2 | Neuropeptide FF receptor 2 | Mus musculus (Mouse) | PR |
| P34971 | Adrb1 | Beta-1 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q91ZY2 | Hrh4 | Histamine H4 receptor | Mus musculus (Mouse) | PR |
| O88416 | Gpr33 | Probable G-protein coupled receptor 33 | Mus musculus (Mouse) | PR |
| Q8K087 | Cmklr2 | Chemerin-like receptor 2 | Mus musculus (Mouse) | PR |
| P70658 | Cxcr4 | C-X-C chemokine receptor type 4 | Mus musculus (Mouse) | PR |
| Q9WV08 | Aplnr | Apelin receptor | Mus musculus (Mouse) | PR |
| P97718 | Adra1a | Alpha-1A adrenergic receptor | Mus musculus (Mouse) | PR |
| Q8BZP8 | Npsr1 | Neuropeptide S receptor | Mus musculus (Mouse) | PR |
| Q8K458 | Prokr2 | Prokineticin receptor 2 | Mus musculus (Mouse) | PR |
| P58308 | Hcrtr2 | Orexin receptor type 2 | Mus musculus (Mouse) | PR |
| Q7TQP3 | Gpr119 | Glucose-dependent insulinotropic receptor | Mus musculus (Mouse) | PR |
| Q8BGE9 | Rxfp3 | Relaxin-3 receptor 1 | Mus musculus (Mouse) | PR |
| Q6VZZ7 | Opn5 | Opsin-5 | Mus musculus (Mouse) | PR |
| Q8CIM5 | Gpr84 | G-protein coupled receptor 84 | Mus musculus (Mouse) | PR |
| P25962 | Adrb3 | Beta-3 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q80UC8 | Gpr139 | Probable G-protein coupled receptor 139 | Mus musculus (Mouse) | PR |
| P0C5I1 | Gpr25 | Probable G-protein coupled receptor 25 | Mus musculus (Mouse) | PR |
| P47936 | Cnr2 | Cannabinoid receptor 2 | Mus musculus (Mouse) | PR |
| Q5QD13 | Taar6 | Trace amine-associated receptor 6 | Mus musculus (Mouse) | PR |
| P35846 | Folr1 | Folate receptor alpha | Mus musculus (Mouse) | PR |
| P58307 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Mus musculus (Mouse) | PR |
| Q8C131 | Hcar1 | Hydroxycarboxylic acid receptor 1 | Mus musculus (Mouse) | PR |
| Q9EQQ4 | Gpr45 | Probable G-protein coupled receptor 45 | Mus musculus (Mouse) | PR |
| B2RPY5 | Gpr161 | G-protein coupled receptor 161 | Mus musculus (Mouse) | PR |
| P97468 | Cmklr1 | Chemerin-like receptor 1 | Mus musculus (Mouse) | PR |
| Q764M9 | CXCR4 | C-X-C chemokine receptor type 4 | Sus scrofa (Pig) | PR |
| Q9EQD2 | Npffr2 | Neuropeptide FF receptor 2 | Rattus norvegicus (Rat) | PR |
| O08565 | Cxcr4 | C-X-C chemokine receptor type 4 | Rattus norvegicus (Rat) | PR |
| Q01717 | Trhr | Thyrotropin-releasing hormone receptor | Rattus norvegicus (Rat) | PR |
| P30936 | Sstr3 | Somatostatin receptor type 3 | Rattus norvegicus (Rat) | PR |
| Q9JHG3 | Aplnr | Apelin receptor | Rattus norvegicus (Rat) | PR |
| P43140 | Adra1a | Alpha-1A adrenergic receptor | Rattus norvegicus (Rat) | PR |
| P19327 | Htr1a | 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Rat) | PR |
| P56719 | Hcrtr2 | Orexin receptor type 2 | Rattus norvegicus (Rat) | PR |
| P28564 | Htr1b | 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Rat) | PR |
| P56718 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Rattus norvegicus (Rat) | PR |
| P28647 | Adora3 | Adenosine receptor A3 | Rattus norvegicus (Rat) | PR |
| P25102 | Hrh2 | Histamine H2 receptor | Rattus norvegicus (Rat) | PR |
| P23944 | Adra1d | Alpha-1D adrenergic receptor | Rattus norvegicus (Rat) | PR |
| Q8R415 | Prokr2 | Prokineticin receptor 2 | Rattus norvegicus (Rat) | PR |
| Q5QD24 | Taar3 | Trace amine-associated receptor 3 | Rattus norvegicus (Rat) | PR |
| P0C0W8 | Gpr139 | Probable G-protein coupled receptor 139 | Rattus norvegicus (Rat) | PR |
| P35370 | Oprl1 | Nociceptin receptor | Rattus norvegicus (Rat) | PR |
| P46090 | Cmklr2 | Chemerin-like receptor 2 | Rattus norvegicus (Rat) | PR |
| O97664 | CMKLR2 | Chemerin-like receptor 2 | Macaca mulatta (Rhesus macaque) | PR |
| O97666 | APLNR | Apelin receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q56H79 | NPSR1 | Neuropeptide S receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q18904 | npr-8 | Probable G-protein coupled receptor npr-8 | Caenorhabditis elegans | PR |
| Q09388 | gar-2 | Muscarinic acetylcholine receptor gar-2 | Caenorhabditis elegans | PR |
| B3DM66 | gpr161 | G-protein coupled receptor 161 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q9W6A6 | opn1mw4 | Green-sensitive opsin-4 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q9W6A5 | opn1mw1 | Green-sensitive opsin-1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYM7 | opn1mw3 | Green-sensitive opsin-3 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYN0 | opn1lw2 | Red-sensitive opsin-2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q90X46 | gpr161 | G-protein coupled receptor 161 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRMEDEDYNT | SISYGDEYPD | YLDSIVVLED | LSPLEARVTR | IFLVVVYSIV | CFLGILGNGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VIIIATFKMK | KTVNMVWFLN | LAVADFLFNV | FLPIHITYAA | MDYHWVFGTA | MCKISNFLLI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HNMFTSVFLL | TIISSDRCIS | VLLPVWSQNH | RSVRLAYMAC | MVIWVLAFFL | SSPSLVFRDT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ANLHGKISCF | NNFSLSTPGS | SSWPTHSQMD | PVGYSRHMVV | TVTRFLCGFL | VPVLIITACY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LTIVCKLQRN | RLAKTKKPFK | IIVTIIITFF | LCWCPYHTLN | LLELHHTAMP | GSVFSLGLPL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ATALAIANSC | MNPILYVFMG | QDFKKFKVAL | FSRLVNALSE | DTGHSSYPSH | RSFTKMSSMN |
| 370 | |||||
| ERTSMNERET | GML |