Q9Y5Y3
PR
Gene name |
GPR45 |
Protein name |
Probable G-protein coupled receptor 45 |
Names |
PSP24-1, PSP24-alpha |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:11250 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9Y5Y3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9Y5Y3-F1 | Predicted | AlphaFoldDB |
315 variants for Q9Y5Y3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| TCGA novel | 4 | N>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs748665162 CA1813501 |
5 | S>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748665162 CA348099154 |
5 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1813503 rs770837246 COSM287190 |
6 | T>M | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs770837246 CA1813502 |
6 | T>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| VAR_035759 | 7 | S>C | a breast cancer sample; somatic mutation [UniProt] | No | UniProt |
|
rs1558799266 CA348099172 |
8 | L>P | No |
ClinGen Ensembl |
|
|
CA348099178 rs1413055660 |
9 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
CA348099175 rs1336356971 |
9 | E>Q | No |
ClinGen gnomAD |
|
|
CA348099193 rs1161155014 |
11 | Y>F | No |
ClinGen gnomAD |
|
|
rs372207201 CA1813505 |
13 | Y>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs980110985 CA53397746 |
14 | L>P | No |
ClinGen TOPMed |
|
|
CA348099210 rs141939363 |
14 | L>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA348099232 rs1330055390 |
18 | T>A | No |
ClinGen TOPMed |
|
|
CA348099252 rs1230597460 |
20 | N>K | No |
ClinGen gnomAD |
|
|
CA348099253 COSM1527023 rs1289396618 |
21 | A>T | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA1813509 rs145079238 |
21 | A>V | No |
ClinGen ESP ExAC TOPMed |
|
|
rs550462737 CA1813510 |
22 | S>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs766721869 CA1813511 |
24 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs1302425649 CA348099293 |
27 | T>I | No |
ClinGen TOPMed |
|
|
CA1813514 rs765340371 |
28 | Q>P | No |
ClinGen ExAC gnomAD |
|
|
rs1184025734 CA348099313 |
30 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs746939000 CA1813518 COSM1004747 |
31 | A>S | endometrium [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA1813519 rs746939000 |
31 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA53397792 rs983351931 |
32 | P>S | No |
ClinGen TOPMed |
|
|
rs907774333 CA53397793 |
33 | L>F | No |
ClinGen TOPMed |
|
|
rs1157198306 CA348099337 |
35 | I>V | No |
ClinGen gnomAD |
|
|
CA1813520 COSM168370 rs781291024 |
36 | S>F | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA348099344 rs1472417397 |
36 | S>P | No |
ClinGen gnomAD |
|
|
CA1813521 rs781291024 |
36 | S>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1357883445 CA348099356 |
38 | A>S | No |
ClinGen gnomAD |
|
|
CA348099364 rs1432481721 |
39 | I>T | No |
ClinGen TOPMed |
|
|
CA1813523 rs139229733 |
40 | V>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA53397827 rs144600528 |
41 | M>I | No |
ClinGen ESP |
|
|
rs1190555389 CA348099376 |
41 | M>T | No |
ClinGen TOPMed |
|
|
CA53397850 rs766673600 |
46 | V>A | No |
ClinGen TOPMed |
|
|
rs768136880 CA1813525 |
46 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA348099411 rs1346737783 |
47 | V>G | No |
ClinGen gnomAD |
|
|
CA53397852 rs931707200 |
47 | V>M | No |
ClinGen TOPMed |
|
|
CA348099417 rs1256915190 |
48 | G>E | No |
ClinGen TOPMed |
|
|
CA348099414 rs1573513153 |
48 | G>R | No |
ClinGen Ensembl |
|
|
rs773914555 CA1813526 |
49 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1813530 rs759792071 |
55 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs1402740332 CA348099482 |
58 | I>T | No |
ClinGen gnomAD |
|
|
rs370523818 CA1813532 |
59 | V>A | No |
ClinGen ESP ExAC gnomAD |
|
|
CA1813533 rs763334033 |
62 | R>K | No |
ClinGen ExAC gnomAD |
|
|
CA53397911 rs903481209 |
63 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs533753702 CA1813537 |
66 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA1813536 rs533753702 |
66 | R>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA1813535 rs201195065 |
66 | R>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA1813539 rs755839753 |
67 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348099556 rs1573513229 |
70 | N>T | No |
ClinGen Ensembl |
|
|
CA348099564 rs1326008989 |
71 | L>P | No |
ClinGen gnomAD |
|
|
rs1273667461 CA348099576 |
74 | A>T | No |
ClinGen gnomAD |
|
|
CA348099587 rs1465391003 |
75 | T>N | No |
ClinGen TOPMed |
|
|
rs1573513243 CA348099582 |
75 | T>P | No |
ClinGen Ensembl |
|
|
CA1813543 rs189330575 |
77 | A>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 82 | M>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1170471026 CA348099628 |
82 | M>V | No |
ClinGen TOPMed |
|
|
CA1813544 rs747620860 |
84 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA348099642 rs1315419788 |
84 | S>P | No |
ClinGen gnomAD |
|
| TCGA novel | 86 | C>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348099663 rs1291802702 |
87 | C>Y | No |
ClinGen gnomAD |
|
|
CA1813546 rs776984771 |
88 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs1573513267 CA348099690 |
91 | T>P | No |
ClinGen Ensembl |
|
|
rs1356756765 CA348099694 |
91 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1189342876 CA348099708 |
94 | T>P | No |
ClinGen gnomAD |
|
|
CA348099710 rs1189342876 |
94 | T>S | No |
ClinGen gnomAD |
|
|
CA348099737 rs1165326711 |
98 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
CA348099733 rs1460940995 |
98 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs763424464 CA1813550 |
99 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs763424464 CA1813551 |
99 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA1813552 rs200554082 COSM1527021 |
99 | R>H | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA348099749 rs1322464207 |
100 | W>* | No |
ClinGen TOPMed gnomAD |
|
|
rs1322464207 CA348099748 COSM387062 |
100 | W>C | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
rs61734870 CA53397987 |
104 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
rs1296169376 CA348099790 |
106 | F>V | No |
ClinGen TOPMed |
|
|
CA348099803 rs1341866530 |
107 | C>* | No |
ClinGen TOPMed |
|
|
CA348099798 rs1224676889 |
107 | C>G | No |
ClinGen TOPMed |
|
|
rs1573513314 CA348099800 |
107 | C>S | No |
ClinGen Ensembl |
|
|
rs199769227 CA1813553 |
108 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs140418322 CA1813554 |
109 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA1813555 rs750312491 |
112 | T>R | No |
ClinGen ExAC gnomAD |
|
|
CA348099834 rs1285677959 |
113 | L>H | No |
ClinGen gnomAD |
|
|
CA53398010 rs112707014 |
115 | W>* | No |
ClinGen Ensembl |
|
|
CA1813559 rs371040711 |
118 | V>A | No |
ClinGen ESP ExAC gnomAD |
|
|
CA348099899 rs1573513345 |
123 | A>P | No |
ClinGen Ensembl |
|
|
rs1190201165 CA348099906 |
124 | I>V | No |
ClinGen gnomAD |
|
|
rs1369611602 CA348099912 |
125 | L>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1163283261 CA348099919 |
126 | L>H | No |
ClinGen gnomAD |
|
|
rs1028077098 CA53398024 |
126 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
CA53398030 rs554225455 |
127 | I>V | No |
ClinGen 1000Genomes gnomAD |
|
|
CA53398036 rs952111482 |
131 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
CA348099983 rs1473855544 |
132 | R>C | No |
ClinGen TOPMed |
|
|
rs757834636 CA1813563 |
132 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348099989 rs757834636 |
132 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348099982 rs1473855544 |
132 | R>S | No |
ClinGen TOPMed |
|
|
rs777411177 CA1813564 |
135 | I>N | No |
ClinGen ExAC gnomAD |
|
|
rs746506937 CA1813565 |
136 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA348100041 rs1331441448 |
137 | V>A | No |
ClinGen gnomAD |
|
|
rs572247634 CA1813567 |
137 | V>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs769181230 CA1813569 |
138 | Q>P | No |
ClinGen ExAC gnomAD |
|
|
rs774691771 CA53398057 |
139 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA1813570 rs774691771 |
139 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762181882 CA1813571 |
140 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA1813572 rs767487900 |
141 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA348100105 rs1183378009 |
143 | L>V | No |
ClinGen TOPMed |
|
|
rs766303852 COSM714903 CA1813575 |
145 | P>L | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
| TCGA novel | 145 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs765078347 CA1813578 |
146 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA348100143 COSM261164 rs1483000559 |
146 | R>H | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs758004590 CA1813580 |
147 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA348100168 rs1271548205 |
149 | K>E | No |
ClinGen TOPMed |
|
|
CA53398121 rs145118947 |
150 | V>L | No |
ClinGen ESP ExAC gnomAD |
|
|
rs145118947 CA1813581 |
150 | V>M | No |
ClinGen ESP ExAC gnomAD |
|
|
rs200821166 CA1813583 |
153 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs138940615 CA1813584 |
153 | A>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs749859640 CA1813585 |
154 | V>D | No |
ClinGen ExAC gnomAD |
|
|
CA348100216 rs1558799474 |
154 | V>L | No |
ClinGen Ensembl |
|
|
CA53398129 rs921747850 |
156 | W>C | No |
ClinGen TOPMed |
|
|
rs1265531128 CA348100226 |
156 | W>R | No |
ClinGen TOPMed |
|
|
rs769126007 CA1813586 |
157 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA1813587 rs774918861 |
159 | S>A | No |
ClinGen ExAC gnomAD |
|
|
rs1553454422 CA1813588 |
159 | S>Y | No |
ClinGen Ensembl |
|
|
CA1813590 rs145670700 |
161 | C>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs141953039 CA348100316 |
163 | A>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs141953039 CA348100313 |
163 | A>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
COSM1004748 CA1813592 rs141953039 |
163 | A>T | endometrium [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA348100327 rs1558799486 |
163 | A>V | No |
ClinGen Ensembl |
|
|
CA1813594 rs766423256 |
164 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA1813596 rs759537674 |
165 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs943742352 CA53398167 |
166 | S>* | No |
ClinGen TOPMed gnomAD |
|
|
CA53398169 rs943742352 |
166 | S>L | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 166 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1813597 rs765164320 |
168 | T>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348100371 rs765164320 |
168 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53398181 rs765164320 |
168 | T>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348100381 rs1171673709 |
169 | G>D | No |
ClinGen gnomAD |
|
|
CA1813600 COSM3713354 rs562662336 |
171 | T>M | upper_aerodigestive_tract [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC gnomAD |
|
CA348100428 rs1162769242 |
172 | L>P | No |
ClinGen TOPMed |
|
|
rs754389608 CA1813604 |
174 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA53398199 rs902149476 |
175 | V>M | No |
ClinGen TOPMed |
|
|
CA348100469 rs374437830 |
176 | P>L | No |
ClinGen ESP ExAC gnomAD |
|
|
rs374437830 CA53398203 |
176 | P>Q | No |
ClinGen ESP ExAC gnomAD |
|
|
rs374437830 CA1813605 |
176 | P>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
|
CA1813607 rs752768882 |
177 | A>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1813606 rs779573167 |
177 | A>P | No |
ClinGen ExAC gnomAD |
|
|
CA53398206 rs752768882 |
177 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 179 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348100489 rs757225198 |
179 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1813608 rs757225198 COSM1669188 |
179 | A>T | ovary [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA348100495 rs1479429541 |
180 | P>S | No |
ClinGen gnomAD |
|
|
rs368662446 CA1813609 |
181 | Q>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA348100534 rs747257210 CA1813610 |
183 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA1813611 rs770997380 |
184 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs370457497 CA53398235 |
185 | G>A | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs1450013500 CA348100549 |
185 | G>C | No |
ClinGen gnomAD |
|
|
rs140456971 CA53398239 |
187 | T>A | No |
ClinGen ESP TOPMed |
|
|
CA1813612 rs151145166 |
187 | T>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs140456971 CA348100565 |
187 | T>P | No |
ClinGen ESP TOPMed |
|
|
rs751210465 CA1813618 |
191 | A>P | No |
ClinGen ExAC gnomAD |
|
|
CA348100624 rs751210465 |
191 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs970662249 CA53398291 |
194 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs761439391 CA1813619 |
194 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA1813621 rs749892636 |
196 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA348100686 rs1265654433 |
197 | V>I | No |
ClinGen gnomAD |
|
|
CA348100716 rs1279824133 |
199 | L>F | No |
ClinGen gnomAD |
|
|
CA53398318 rs1014935138 |
200 | V>A | No |
ClinGen gnomAD |
|
|
CA1813623 rs779534228 |
202 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA53398327 rs560190604 |
203 | V>L | No |
ClinGen 1000Genomes gnomAD |
|
|
CA348100744 rs560190604 |
203 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes NCI-TCGA gnomAD |
|
CA1813624 rs527336507 |
206 | A>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA1813625 rs758780573 |
206 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1322590252 CA348100796 |
207 | P>T | No |
ClinGen gnomAD |
|
|
CA53398351 rs962014378 |
209 | G>C | No |
ClinGen TOPMed gnomAD |
|
|
CA348100822 rs1277558189 |
209 | G>D | No |
ClinGen TOPMed |
|
|
CA1813628 rs771083431 |
210 | V>G | No |
ClinGen ExAC gnomAD |
|
|
COSM2981120 CA1813627 rs747405939 |
210 | V>I | pancreas [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1229194789 CA348100868 |
213 | C>W | No |
ClinGen TOPMed gnomAD |
|
|
rs202232782 CA1813629 |
214 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1438851473 CA348100882 |
215 | Y>H | No |
ClinGen TOPMed |
|
|
CA1813630 rs745910123 |
216 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348100927 rs1231098574 |
218 | I>T | No |
ClinGen gnomAD |
|
|
rs769899916 CA1813631 |
219 | L>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA53398378 rs975934405 |
221 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
rs775474130 CA348100961 COSM387063 |
221 | T>M | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs775474130 CA1813632 |
221 | T>R | No |
ClinGen ExAC gnomAD |
|
|
rs1182162078 CA348100975 COSM3938446 |
223 | R>C | oesophagus [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs1256576888 CA348100976 |
223 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1256576888 CA348100978 |
223 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1256576888 CA348100977 |
223 | R>P | No |
ClinGen TOPMed gnomAD |
|
|
rs200019068 CA1813634 |
225 | N>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs773946510 CA1813635 |
226 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA1813637 rs767227335 |
227 | V>E | No |
ClinGen ExAC gnomAD |
|
|
rs1400185024 CA348101000 |
227 | V>L | No |
ClinGen gnomAD |
|
|
rs750129453 CA1813638 |
228 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348101007 rs1449445706 |
228 | R>P | No |
ClinGen gnomAD |
|
|
rs201940295 CA348101021 |
230 | H>Q | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA348101037 rs1446096457 |
232 | Q>H | No |
ClinGen TOPMed |
|
|
rs1412111352 CA348101031 |
232 | Q>K | No |
ClinGen gnomAD |
|
|
rs1289831207 CA348101034 |
232 | Q>P | No |
ClinGen gnomAD |
|
|
rs1289831207 CA348101035 |
232 | Q>R | No |
ClinGen gnomAD |
|
|
rs1573513703 CA348101039 |
233 | S>T | No |
ClinGen Ensembl |
|
|
CA1813639 rs760243757 |
233 | S>W | No |
ClinGen ExAC gnomAD |
|
|
rs1313840998 CA348101052 |
235 | S>R | No |
ClinGen gnomAD |
|
|
CA1813641 rs753248193 |
236 | L>Q | No |
ClinGen ExAC gnomAD |
|
|
CA348101079 rs1484547932 |
239 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA348101083 rs1232159036 |
240 | Q>E | No |
ClinGen TOPMed |
|
|
CA1813643 rs764676645 |
243 | R>S | No |
ClinGen ExAC gnomAD |
|
|
rs376184501 CA348101111 |
244 | A>E | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA53398424 rs376184501 |
244 | A>V | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA1813644 rs751822459 |
245 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA53398451 rs143245552 |
247 | R>Q | No |
ClinGen ESP TOPMed |
|
|
COSM569184 CA1813645 rs757651651 |
247 | R>W | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA348101128 rs1173529372 |
248 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA53398460 COSM1398580 rs369449960 |
248 | R>H | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP NCI-TCGA TOPMed |
|
rs369449960 CA348101130 |
248 | R>L | No |
ClinGen ESP TOPMed |
|
|
rs201182325 CA1813647 |
249 | L>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs746136645 CA1813648 |
250 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348101142 rs112504064 |
251 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA348101143 rs780064917 |
251 | R>L | No |
ClinGen ExAC gnomAD |
|
|
CA1813650 rs780064917 |
251 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs112504064 CA1813649 |
251 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA348101167 rs143732878 |
254 | Q>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1573513780 CA348101172 |
255 | V>G | No |
ClinGen Ensembl |
|
|
CA348101169 rs1277213574 |
255 | V>I | No |
ClinGen gnomAD |
|
|
rs1451883726 CA348101178 |
256 | S>N | No |
ClinGen TOPMed |
|
|
CA53398492 rs934984070 |
257 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs934984070 CA348101183 |
257 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA348101194 rs768416385 |
258 | D>E | No |
ClinGen ExAC gnomAD |
|
|
rs774366129 CA1813653 |
259 | L>S | No |
ClinGen ExAC gnomAD |
|
|
CA348101211 rs1474863348 |
261 | F>V | No |
ClinGen TOPMed |
|
|
rs111311547 CA53398498 |
262 | K>R | No |
ClinGen Ensembl |
|
|
CA1813654 rs747909232 |
263 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs1211963159 CA348101234 |
264 | K>R | No |
ClinGen TOPMed |
|
|
CA1813655 rs772045210 |
271 | I>F | No |
ClinGen ExAC gnomAD |
|
|
rs772988591 CA1813656 |
271 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA1813657 rs760474889 |
273 | F>S | No |
ClinGen ExAC gnomAD |
|
|
rs1442842968 CA348101296 |
274 | V>L | No |
ClinGen TOPMed |
|
|
CA53398513 rs937515441 |
277 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA53398518 rs138866799 |
278 | L>I | No |
ClinGen ESP gnomAD |
|
|
rs539216616 CA1813659 |
279 | C>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA348101334 rs1396253161 COSM3364193 |
280 | W>* | kidney [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA348101352 rs1371546648 |
283 | H>D | No |
ClinGen gnomAD |
|
|
rs1573513867 CA348101354 |
283 | H>P | No |
ClinGen Ensembl |
|
|
CA348101358 rs1226567213 COSM714900 |
283 | H>Q | lung [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA1813660 rs759108867 |
286 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA348101372 rs1573513878 |
286 | Y>H | No |
ClinGen Ensembl |
|
|
CA1813662 rs752102168 |
287 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1573513882 CA348101378 |
287 | S>R | No |
ClinGen Ensembl |
|
|
rs757594370 CA1813663 |
290 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1813664 rs767926021 |
292 | F>I | No |
ClinGen ExAC gnomAD |
|
|
rs1230552552 CA348101425 |
294 | Q>P | No |
ClinGen gnomAD |
|
|
rs1447888691 CA348101432 |
295 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs750639584 CA1813665 COSM200377 |
295 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1447888691 CA348101430 |
295 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
CA348101435 rs1286243828 |
296 | F>I | No |
ClinGen TOPMed |
|
| TCGA novel | 297 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs375629461 CA348101458 |
298 | C>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs780333283 CA53398549 |
299 | G>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs780333283 CA1813667 |
299 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1371766892 CA348101462 |
299 | G>V | No |
ClinGen TOPMed |
|
|
rs1213074882 CA348101476 |
302 | F>I | No |
ClinGen gnomAD |
|
|
rs1251250626 CA348101484 |
303 | Y>H | No |
ClinGen gnomAD |
|
|
rs1005354962 CA53398550 |
304 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA1813669 rs755114729 |
305 | T>N | No |
ClinGen ExAC gnomAD |
|
|
COSM171693 CA53398556 rs1014931172 |
309 | V>I | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA1813671 VAR_049394 rs35946826 |
312 | L>F | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs773078857 CA1813673 |
319 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA1813675 rs746818166 COSM381473 |
320 | N>K | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA1813676 rs776377304 |
321 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA1813678 rs953279063 |
322 | I>L | No |
ClinGen TOPMed |
|
|
rs758939694 CA1813680 |
322 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1285738675 CA348101613 |
323 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA348101625 rs1232922107 |
324 | Y>* | No |
ClinGen gnomAD |
|
|
CA1813682 rs774823465 |
324 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774823465 CA348101623 |
324 | Y>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1271558791 CA348101626 |
325 | C>S | No |
ClinGen TOPMed gnomAD |
|
|
rs762373048 CA1813683 |
325 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
CA1813684 rs372741548 |
326 | W>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA1813685 rs750727237 |
328 | I>N | No |
ClinGen ExAC gnomAD |
|
|
rs1258687311 CA348101673 |
331 | F>Y | No |
ClinGen gnomAD |
|
|
CA1813686 rs761119993 COSM1398584 |
332 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA348101680 rs1352198171 COSM148920 |
332 | R>H | Variant assessed as Somatic; impact. central_nervous_system stomach [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs766468335 CA348101683 |
333 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1813687 rs766468335 |
333 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1813689 rs755001691 |
334 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754127381 CA1813688 |
334 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348101693 rs755001691 |
334 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1449293820 CA348101703 |
336 | I>V | No |
ClinGen gnomAD |
|
| TCGA novel | 337 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs752832419 CA1813691 COSM1613251 |
340 | P>L | liver [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA1813692 rs201875537 |
342 | T>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA53398666 rs200226637 |
345 | I>T | No |
ClinGen TOPMed |
|
| TCGA novel | 349 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1352620324 CA348101797 |
350 | P>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA53398672 rs1003479730 |
350 | P>S | No |
ClinGen Ensembl |
|
|
rs746761296 CA1813694 |
352 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA1813695 rs770801979 |
352 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348101815 rs1202684999 |
353 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA53398686 rs751905324 |
354 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1281720099 CA348101826 |
355 | R>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
| TCGA novel | 357 | I>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs780688429 CA1813696 |
361 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348101874 rs1254889885 |
362 | V>A | No |
ClinGen gnomAD |
|
|
CA348101885 rs377185135 |
364 | V>L | No |
ClinGen ESP ExAC gnomAD |
|
|
COSM1004750 rs377185135 CA1813698 |
364 | V>M | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA gnomAD |
|
rs1451056384 CA348101898 |
366 | N>D | No |
ClinGen gnomAD |
|
|
rs267598823 CA53398696 |
367 | E>K | No |
ClinGen Ensembl |
|
|
CA348101920 rs1376066935 |
369 | Q>K | No |
ClinGen gnomAD |
|
|
CA348101929 rs1433849643 |
370 | S>P | No |
ClinGen TOPMed gnomAD |
|
|
rs1433849643 CA348101928 |
370 | S>T | No |
ClinGen TOPMed gnomAD |
|
|
CA1813700 rs762463206 |
371 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs879189805 CA53398737 |
373 | V>L | No |
ClinGen Ensembl |
|
|
rs1393176319 CA348101951 |
373 | V>Y | No |
ClinGen gnomAD |
No associated diseases with Q9Y5Y3
1 regional properties for Q9Y5Y3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 43 - 285 | IPR017452 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled receptor activity | Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| G protein-coupled receptor signaling pathway | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
119 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2YDN1 | GPR161 | G protein-coupled receptor 161 | Bos taurus (Bovine) | PR |
| Q0GBZ5 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Bos taurus (Bovine) | PR |
| Q17QD8 | GPR37L1 | G-protein coupled receptor 37-like 1 | Bos taurus (Bovine) | PR |
| Q8SPN1 | PROKR2 | Prokineticin receptor 2 | Bos taurus (Bovine) | PR |
| P46626 | ADRB3 | Beta-3 adrenergic receptor | Bos taurus (Bovine) | PR |
| O46639 | TRHR | Thyrotropin-releasing hormone receptor | Bos taurus (Bovine) | PR |
| Q8SPN2 | PROKR1 | Prokineticin receptor 1 | Bos taurus (Bovine) | PR |
| B9VR26 | CMLKR1 | Chemerin-like receptor 1 | Bos taurus (Bovine) | PR |
| P18130 | ADRA1A | Alpha-1A adrenergic receptor | Bos taurus (Bovine) | PR |
| B4XF06 | GPR39 | G-protein coupled receptor 39 | Bos taurus (Bovine) | PR |
| O18913 | OPN1LW | Long-wave-sensitive opsin 1 | Felis catus (Cat) (Felis silvestris catus) | PR |
| P28683 | PRA1 | Green-sensitive opsin | Gallus gallus (Chicken) | PR |
| Q9N298 | HTR1A | 5-hydroxytryptamine receptor 1A | Pan troglodytes (Chimpanzee) | PR |
| P08099 | Rh2 | Opsin Rh2 | Drosophila melanogaster (Fruit fly) | PR |
| P06002 | ninaE | Opsin Rh1 | Drosophila melanogaster (Fruit fly) | PR |
| Q4LBB9 | Octbeta2R | Octopamine receptor beta-2R | Drosophila melanogaster (Fruit fly) | PR |
| Q8NFJ6 | PROKR2 | Prokineticin receptor 2 | Homo sapiens (Human) | PR |
| Q13585 | GPR50 | Melatonin-related receptor | Homo sapiens (Human) | PR |
| Q9H3N8 | HRH4 | Histamine H4 receptor | Homo sapiens (Human) | PR |
| P28336 | NMBR | Neuromedin-B receptor | Homo sapiens (Human) | PR |
| P08913 | ADRA2A | Alpha-2A adrenergic receptor | Homo sapiens (Human) | PR |
| P41597 | CCR2 | C-C chemokine receptor type 2 | Homo sapiens (Human) | PR |
| P51681 | CCR5 | C-C chemokine receptor type 5 | Homo sapiens (Human) | PR |
| Q8TCW9 | PROKR1 | Prokineticin receptor 1 | Homo sapiens (Human) | PR |
| Q99788 | CMKLR1 | Chemerin-like receptor 1 | Homo sapiens (Human) | PR |
| P08908 | HTR1A | 5-hydroxytryptamine receptor 1A | Homo sapiens (Human) | PR |
| P30559 | OXTR | Oxytocin receptor | Homo sapiens (Human) | PR |
| P32239 | CCKBR | Gastrin/cholecystokinin type B receptor | Homo sapiens (Human) | PR |
| O60883 | GPR37L1 | G-protein coupled receptor 37-like 1 | Homo sapiens (Human) | PR |
| Q8TDU9 | RXFP4 | Relaxin-3 receptor 2 | Homo sapiens (Human) | PR |
| P04000 | OPN1LW | Long-wave-sensitive opsin 1 | Homo sapiens (Human) | PR |
| Q6U736 | OPN5 | Opsin-5 | Homo sapiens (Human) | PR |
| P34972 | CNR2 | Cannabinoid receptor 2 | Homo sapiens (Human) | PR |
| P24530 | EDNRB | Endothelin receptor type B | Homo sapiens (Human) | PR |
| P35348 | ADRA1A | Alpha-1A adrenergic receptor | Homo sapiens (Human) | PR |
| Q6W5P4 | NPSR1 | Neuropeptide S receptor | Homo sapiens (Human) | PR |
| O43613 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Homo sapiens (Human) | PR |
| P61073 | CXCR4 | C-X-C chemokine receptor type 4 | Homo sapiens (Human) | PR |
| Q9BXC0 | HCAR1 | Hydroxycarboxylic acid receptor 1 | Homo sapiens (Human) | PR |
| P30556 | AGTR1 | Type-1 angiotensin II receptor | Homo sapiens (Human) | PR |
| Q15761 | NPY5R | Neuropeptide Y receptor type 5 | Homo sapiens (Human) | PR |
| Q8N6U8 | GPR161 | G-protein coupled receptor 161 | Homo sapiens (Human) | PR |
| Q6DWJ6 | GPR139 | Probable G-protein coupled receptor 139 | Homo sapiens (Human) | PR |
| P21462 | FPR1 | fMet-Leu-Phe receptor | Homo sapiens (Human) | PR |
| P35414 | APLNR | Apelin receptor | Homo sapiens (Human) | PR |
| P46091 | CMKLR2 | Chemerin-like receptor 2 | Homo sapiens (Human) | PR |
| P32745 | SSTR3 | Somatostatin receptor type 3 | Homo sapiens (Human) | PR |
| P41439 | FOLR3 | Folate receptor gamma | Homo sapiens (Human) | PR |
| Q9BZJ6 | GPR63 | Probable G-protein coupled receptor 63 | Homo sapiens (Human) | PR |
| P19973 | Lsp1 | Lymphocyte-specific protein 1 | Mus musculus (Mouse) | PR |
| O54799 | Nmbr | Neuromedin-B receptor | Mus musculus (Mouse) | PR |
| Q64264 | Htr1a | 5-hydroxytryptamine receptor 1A | Mus musculus (Mouse) | PR |
| P51675 | Ccr1 | C-C chemokine receptor type 1 | Mus musculus (Mouse) | PR |
| Q5U431 | Gpr39 | G-protein coupled receptor 39 | Mus musculus (Mouse) | PR |
| Q99JG2 | Gpr37l1 | G-protein coupled receptor 37-like 1 | Mus musculus (Mouse) | PR |
| P97295 | Npy2r | Neuropeptide Y receptor type 2 | Mus musculus (Mouse) | PR |
| O08786 | Cckar | Cholecystokinin receptor type A | Mus musculus (Mouse) | PR |
| P56481 | Cckbr | Gastrin/cholecystokinin type B receptor | Mus musculus (Mouse) | PR |
| P30731 | Gpr83 | G-protein coupled receptor 83 | Mus musculus (Mouse) | PR |
| P97468 | Cmklr1 | Chemerin-like receptor 1 | Mus musculus (Mouse) | PR |
| P21761 | Trhr | Thyrotropin-releasing hormone receptor | Mus musculus (Mouse) | PR |
| Q5QD16 | Taar3 | Trace amine-associated receptor 3 | Mus musculus (Mouse) | PR |
| P97292 | Hrh2 | Histamine H2 receptor | Mus musculus (Mouse) | PR |
| Q9EQQ3 | Gpr63 | Probable G-protein coupled receptor 63 | Mus musculus (Mouse) | PR |
| Q924H0 | Npffr2 | Neuropeptide FF receptor 2 | Mus musculus (Mouse) | PR |
| P34971 | Adrb1 | Beta-1 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q91ZY2 | Hrh4 | Histamine H4 receptor | Mus musculus (Mouse) | PR |
| O88416 | Gpr33 | Probable G-protein coupled receptor 33 | Mus musculus (Mouse) | PR |
| Q8K087 | Cmklr2 | Chemerin-like receptor 2 | Mus musculus (Mouse) | PR |
| P70658 | Cxcr4 | C-X-C chemokine receptor type 4 | Mus musculus (Mouse) | PR |
| Q9WV08 | Aplnr | Apelin receptor | Mus musculus (Mouse) | PR |
| P97718 | Adra1a | Alpha-1A adrenergic receptor | Mus musculus (Mouse) | PR |
| Q8BZP8 | Npsr1 | Neuropeptide S receptor | Mus musculus (Mouse) | PR |
| Q8K458 | Prokr2 | Prokineticin receptor 2 | Mus musculus (Mouse) | PR |
| P58308 | Hcrtr2 | Orexin receptor type 2 | Mus musculus (Mouse) | PR |
| Q7TQP3 | Gpr119 | Glucose-dependent insulinotropic receptor | Mus musculus (Mouse) | PR |
| Q8BGE9 | Rxfp3 | Relaxin-3 receptor 1 | Mus musculus (Mouse) | PR |
| Q6VZZ7 | Opn5 | Opsin-5 | Mus musculus (Mouse) | PR |
| Q8CIM5 | Gpr84 | G-protein coupled receptor 84 | Mus musculus (Mouse) | PR |
| P25962 | Adrb3 | Beta-3 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q80UC8 | Gpr139 | Probable G-protein coupled receptor 139 | Mus musculus (Mouse) | PR |
| P0C5I1 | Gpr25 | Probable G-protein coupled receptor 25 | Mus musculus (Mouse) | PR |
| P47936 | Cnr2 | Cannabinoid receptor 2 | Mus musculus (Mouse) | PR |
| Q5QD13 | Taar6 | Trace amine-associated receptor 6 | Mus musculus (Mouse) | PR |
| P35846 | Folr1 | Folate receptor alpha | Mus musculus (Mouse) | PR |
| P58307 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Mus musculus (Mouse) | PR |
| Q8C131 | Hcar1 | Hydroxycarboxylic acid receptor 1 | Mus musculus (Mouse) | PR |
| B2RPY5 | Gpr161 | G-protein coupled receptor 161 | Mus musculus (Mouse) | PR |
| Q9EQQ4 | Gpr45 | Probable G-protein coupled receptor 45 | Mus musculus (Mouse) | PR |
| Q764M9 | CXCR4 | C-X-C chemokine receptor type 4 | Sus scrofa (Pig) | PR |
| Q9EQD2 | Npffr2 | Neuropeptide FF receptor 2 | Rattus norvegicus (Rat) | PR |
| O08565 | Cxcr4 | C-X-C chemokine receptor type 4 | Rattus norvegicus (Rat) | PR |
| Q01717 | Trhr | Thyrotropin-releasing hormone receptor | Rattus norvegicus (Rat) | PR |
| P30936 | Sstr3 | Somatostatin receptor type 3 | Rattus norvegicus (Rat) | PR |
| Q9JHG3 | Aplnr | Apelin receptor | Rattus norvegicus (Rat) | PR |
| P43140 | Adra1a | Alpha-1A adrenergic receptor | Rattus norvegicus (Rat) | PR |
| P19327 | Htr1a | 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Rat) | PR |
| P56719 | Hcrtr2 | Orexin receptor type 2 | Rattus norvegicus (Rat) | PR |
| P28564 | Htr1b | 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Rat) | PR |
| P56718 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Rattus norvegicus (Rat) | PR |
| P28647 | Adora3 | Adenosine receptor A3 | Rattus norvegicus (Rat) | PR |
| P25102 | Hrh2 | Histamine H2 receptor | Rattus norvegicus (Rat) | PR |
| P23944 | Adra1d | Alpha-1D adrenergic receptor | Rattus norvegicus (Rat) | PR |
| Q8R415 | Prokr2 | Prokineticin receptor 2 | Rattus norvegicus (Rat) | PR |
| Q5QD24 | Taar3 | Trace amine-associated receptor 3 | Rattus norvegicus (Rat) | PR |
| P0C0W8 | Gpr139 | Probable G-protein coupled receptor 139 | Rattus norvegicus (Rat) | PR |
| P35370 | Oprl1 | Nociceptin receptor | Rattus norvegicus (Rat) | PR |
| P46090 | Cmklr2 | Chemerin-like receptor 2 | Rattus norvegicus (Rat) | PR |
| O97664 | CMKLR2 | Chemerin-like receptor 2 | Macaca mulatta (Rhesus macaque) | PR |
| O97666 | APLNR | Apelin receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q56H79 | NPSR1 | Neuropeptide S receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q18904 | npr-8 | Probable G-protein coupled receptor npr-8 | Caenorhabditis elegans | PR |
| Q09388 | gar-2 | Muscarinic acetylcholine receptor gar-2 | Caenorhabditis elegans | PR |
| B3DM66 | gpr161 | G-protein coupled receptor 161 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q9W6A6 | opn1mw4 | Green-sensitive opsin-4 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q9W6A5 | opn1mw1 | Green-sensitive opsin-1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYM7 | opn1mw3 | Green-sensitive opsin-3 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYN0 | opn1lw2 | Red-sensitive opsin-2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q90X46 | gpr161 | G-protein coupled receptor 161 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MACNSTSLEA | YTYLLLNTSN | ASDSGSTQLP | APLRISLAIV | MLLMTVVGFL | GNTVVCIIVY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QRPAMRSAIN | LLLATLAFSD | IMLSLCCMPF | TAVTLITVRW | HFGDHFCRLS | ATLYWFFVLE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GVAILLIISV | DRFLIIVQRQ | DKLNPRRAKV | IIAVSWVLSF | CIAGPSLTGW | TLVEVPARAP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QCVLGYTELP | ADRAYVVTLV | VAVFFAPFGV | MLCAYMCILN | TVRKNAVRVH | NQSDSLDLRQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LTRAGLRRLQ | RQQQVSVDLS | FKTKAFTTIL | ILFVGFSLCW | LPHSVYSLLS | VFSQRFYCGS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SFYATSTCVL | WLSYLKSVFN | PIVYCWRIKK | FREACIELLP | QTFQILPKVP | ERIRRRIQPS |
| 370 | |||||
| TVYVCNENQS | AV |