Q13585
PR
Gene name |
GPR50 |
Protein name |
Melatonin-related receptor |
Names |
G protein-coupled receptor 50, H9 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:9248 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q13585
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q13585-F1 | Predicted | AlphaFoldDB |
450 variants for Q13585
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA415266263 rs1317478046 |
3 | P>S | No |
ClinGen gnomAD |
|
|
rs1215653895 CA415266275 |
5 | L>V | No |
ClinGen gnomAD |
|
|
rs1157091999 CA415266284 |
6 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs781043035 CA10540172 |
7 | V>F | No |
ClinGen ExAC gnomAD |
|
|
CA10540173 rs201148153 |
10 | P>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10540175 rs779004211 |
11 | Y>C | No |
ClinGen ExAC gnomAD |
|
| rs1412998291 | 11 | Y>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs748396836 CA10540176 |
12 | G>D | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 12 | G>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs772236698 CA10540178 |
14 | I>M | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 15 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1438644948 CA415266346 |
16 | C>W | No |
ClinGen gnomAD |
|
|
CA10540179 rs747267730 |
17 | K>Q | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 19 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA415266366 rs1190783820 |
20 | Q>E | No |
ClinGen TOPMed |
|
|
CA10540180 rs771355848 |
20 | Q>L | No |
ClinGen ExAC gnomAD |
|
|
rs368281686 CA10540181 |
21 | P>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs760172323 CA10540182 |
23 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
rs376483511 CA10540183 |
25 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376483511 CA415266401 |
25 | P>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376483511 CA415266402 |
25 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1338727042 CA415266404 |
26 | A>P | No |
ClinGen gnomAD |
|
|
rs1042295670 CA337194871 |
27 | L>V | No |
ClinGen gnomAD |
|
| TCGA novel | 31 | M>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM272004 rs903144898 CA337194881 |
31 | M>I | large_intestine [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
CA10540185 rs370000417 |
31 | M>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs763596159 CA10540186 |
32 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1352646124 CA415266450 |
33 | C>G | No |
ClinGen gnomAD |
|
|
rs751230928 CA10540187 |
33 | C>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540189 rs372712912 COSM1556770 |
34 | A>E | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA337194890 rs1002895906 |
34 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA415266459 rs372712912 |
34 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs756110895 CA10540191 |
35 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA415266470 rs1178926721 |
36 | V>F | No |
ClinGen TOPMed gnomAD |
|
|
rs1178926721 CA415266468 |
36 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
CA337194949 rs189225995 |
38 | T>I | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs189225995 CA337194948 |
38 | T>S | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs374835856 CA10540192 |
39 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA337194972 rs780149081 |
41 | V>I | No |
ClinGen Ensembl |
|
|
rs1358231512 CA415266507 |
42 | D>V | No |
ClinGen gnomAD |
|
|
rs1178684632 CA415266523 |
45 | G>R | No |
ClinGen gnomAD |
|
|
CA415266532 rs1335216965 |
46 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1446114524 CA415266545 |
48 | M>T | No |
ClinGen gnomAD |
|
|
rs748115693 CA10540193 |
48 | M>V | No |
ClinGen ExAC gnomAD |
|
|
CA415266552 rs1431717214 |
49 | V>F | No |
ClinGen TOPMed |
|
|
rs777815917 CA10540195 |
50 | I>V | No |
ClinGen ExAC |
|
|
CA10540198 rs200181373 |
54 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540197 rs200181373 |
54 | T>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1408736639 CA415266588 |
55 | K>T | No |
ClinGen gnomAD |
|
| TCGA novel | 56 | N>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs776077410 CA337195007 |
57 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770481834 CA10540200 |
57 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415266609 rs1256061059 |
58 | K>E | No |
ClinGen gnomAD |
|
|
CA10540204 COSM267855 rs375887607 |
60 | R>Q | large_intestine [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA10540203 rs372854533 |
60 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs760418647 CA10540226 |
65 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766181640 COSM1132374 CA10540227 |
67 | V>M | prostate [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA10540229 rs759561321 |
73 | A>D | No |
ClinGen ExAC gnomAD |
|
|
CA10540228 rs753699132 |
73 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA10540230 rs764080839 |
74 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415266729 rs1569566965 |
75 | M>K | No |
ClinGen Ensembl |
|
|
rs751723921 CA10540231 |
77 | V>G | No |
ClinGen ExAC gnomAD |
|
|
rs371241834 CA337196463 |
77 | V>M | No |
ClinGen ESP |
|
|
CA10540232 rs757426689 |
78 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA415266778 rs1486773032 |
83 | P>T | No |
ClinGen gnomAD |
|
|
CA337196505 rs908301393 |
85 | M>I | No |
ClinGen Ensembl |
|
|
CA415266799 rs1389763290 |
86 | L>M | No |
ClinGen TOPMed |
|
|
rs1243406118 CA415266803 |
86 | L>P | No |
ClinGen gnomAD |
|
|
COSM3708482 rs1284467175 CA415266822 |
89 | M>T | liver [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs868643109 CA337196510 |
90 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs868643109 CA415266831 |
90 | S>Y | No |
ClinGen gnomAD |
|
|
CA10540233 rs781499377 |
91 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA415266842 rs750707900 |
92 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750707900 CA415266841 |
92 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540234 rs750707900 |
92 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415266846 rs769016022 |
93 | G>A | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10540235 rs769016022 |
93 | G>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10540236 rs780505218 |
96 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415266884 rs1440804421 |
98 | Q>H | No |
ClinGen gnomAD |
|
|
rs769263824 CA10540238 |
103 | M>I | No |
ClinGen ExAC gnomAD |
|
|
rs376093395 CA10540237 |
103 | M>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs771598289 CA10540241 |
105 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA10540240 rs747586113 |
105 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772799343 CA10540242 |
108 | T>K | No |
ClinGen ExAC gnomAD |
|
|
rs1394979471 CA415266956 |
109 | G>E | No |
ClinGen gnomAD |
|
| TCGA novel | 112 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs772438504 CA415266985 |
114 | G>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10540245 rs772438504 |
114 | G>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10540246 rs759381821 |
114 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA10540247 rs765167544 |
116 | I>L | No |
ClinGen ExAC gnomAD |
|
|
CA415266997 rs1240165897 |
116 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1569566967 CA415267003 |
117 | F>Y | No |
ClinGen Ensembl |
|
|
CA415267012 rs1263043976 |
118 | N>S | No |
ClinGen gnomAD |
|
|
rs1199952495 CA415267025 |
120 | V>M | No |
ClinGen gnomAD |
|
|
CA415267046 rs767729782 |
123 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415267042 rs1462706023 |
123 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA10540250 rs767729782 |
123 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750653111 CA10540251 |
124 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs766638424 CA10540253 |
125 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540254 rs754172257 |
126 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415267062 rs755302073 COSM355790 |
126 | R>H | lung [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs755302073 CA10540255 |
126 | R>P | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 133 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10540256 rs779432297 |
134 | L>R | No |
ClinGen ExAC gnomAD |
|
|
rs377409392 CA10540258 |
137 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs764196997 CA415267148 |
138 | R>P | No |
ClinGen gnomAD |
|
|
rs764196997 CA337196727 |
138 | R>Q | No |
ClinGen gnomAD |
|
|
rs900102278 CA337196719 |
138 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA415267152 rs1392354484 |
139 | I>F | No |
ClinGen gnomAD |
|
|
CA337196732 rs1042955180 |
140 | F>S | No |
ClinGen Ensembl |
|
|
CA415267169 rs1309528719 |
141 | S>N | No |
ClinGen gnomAD |
|
|
CA415267167 rs1309528719 |
141 | S>T | No |
ClinGen gnomAD |
|
|
CA415267180 rs1329859807 |
143 | R>C | No |
ClinGen gnomAD |
|
|
COSM3390481 rs370115563 CA10540259 |
143 | R>H | pancreas [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs746663885 CA10540260 |
144 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540261 rs770679290 |
148 | Y>H | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 149 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs745610748 CA10540263 |
150 | V>F | No |
ClinGen ExAC gnomAD |
|
|
rs775520411 CA10540265 |
157 | V>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540266 rs775520411 |
157 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415267299 rs1432384935 |
162 | P>T | No |
ClinGen gnomAD |
|
|
CA10540269 rs760683612 |
164 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540270 rs766555392 |
168 | T>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 168 | T>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10540271 rs754033816 |
169 | I>F | No |
ClinGen ExAC gnomAD |
|
|
rs367944030 CA10540272 |
169 | I>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs372045629 CA10540274 |
170 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs755414121 CA337196863 |
172 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
CA10540276 rs374353730 |
172 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1446061909 CA415267381 |
174 | R>C | No |
ClinGen TOPMed |
|
|
CA10540277 rs201701013 |
174 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA10540278 rs756727614 |
177 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753060369 CA337196909 |
178 | C>R | No |
ClinGen gnomAD |
|
|
CA10540279 rs766762255 |
184 | N>Y | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs780037380 CA10540282 |
190 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1192300901 CA415267502 |
192 | I>T | No |
ClinGen gnomAD |
|
|
rs768655839 COSM206074 CA10540284 |
193 | V>I | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA415267522 rs1162317136 |
195 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA10540285 rs202126801 |
196 | H>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 198 | V>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10540287 COSM1466315 rs770934441 |
198 | V>I | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA415267540 rs770934441 |
198 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA415267548 rs1368018425 |
199 | L>P | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1318729967 CA415267571 |
203 | I>V | No |
ClinGen gnomAD |
|
|
CA415267577 rs1288793743 |
204 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs759714911 CA10540289 |
205 | G>A | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 207 | C>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1172874873 CA415267598 |
207 | C>Y | No |
ClinGen TOPMed |
|
|
rs1310902519 CA415267607 |
208 | Y>C | No |
ClinGen gnomAD |
|
|
CA337197014 rs367648979 |
209 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs765579691 CA10540290 |
217 | A>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765579691 CA10540291 |
217 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 218 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10540294 rs764521707 |
219 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415267675 rs1215052835 |
219 | R>H | No |
ClinGen gnomAD |
|
|
CA10540293 rs764521707 |
219 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415267696 rs1486584592 |
222 | A>V | No |
ClinGen gnomAD |
|
|
rs780617050 CA415267698 CA10540296 |
223 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs965148805 CA337197110 |
226 | P>L | No |
ClinGen Ensembl |
|
|
rs750061222 CA10540297 |
227 | D>H | No |
ClinGen ExAC gnomAD |
|
|
CA10540298 rs755778249 |
227 | D>V | No |
ClinGen ExAC |
|
|
rs1489440959 CA415267732 |
228 | N>H | No |
ClinGen TOPMed |
|
|
CA415267756 rs1418241293 |
231 | A>G | No |
ClinGen gnomAD |
|
|
rs749023791 CA10540300 |
233 | V>F | No |
ClinGen ExAC gnomAD |
|
|
rs768602851 CA10540301 |
234 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA415267773 rs1433023729 |
234 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1301101684 CA415267798 |
238 | T>A | No |
ClinGen gnomAD |
|
|
CA415267831 rs1602728326 |
242 | I>N | No |
ClinGen Ensembl |
|
|
rs1453734375 CA415267834 |
243 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1489618662 CA415267842 |
244 | L>V | No |
ClinGen gnomAD |
|
|
CA10540303 rs748081183 |
247 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1268568172 CA415267868 |
248 | V>L | No |
ClinGen TOPMed |
|
| TCGA novel | 248 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA415267908 rs776638905 |
253 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs921054298 CA337197162 |
253 | I>V | No |
ClinGen Ensembl |
|
|
CA415267910 rs1269174978 |
254 | N>D | No |
ClinGen gnomAD |
|
|
CA10540307 rs201906872 |
255 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA415267924 rs1241914898 |
256 | L>F | Variant assessed as Somatic; 6.362e-05 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA415267943 rs1432829996 |
259 | L>S | No |
ClinGen TOPMed |
|
|
CA10540310 rs764464450 |
261 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA337197258 rs944098807 |
264 | P>L | No |
ClinGen TOPMed |
|
|
rs1409366851 CA415267981 |
265 | K>R | No |
ClinGen gnomAD |
|
|
rs899987604 CA337197302 |
266 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
CA415267996 rs1174566357 |
267 | M>T | No |
ClinGen gnomAD |
|
|
rs1187647008 CA415268001 |
268 | A>T | No |
ClinGen TOPMed |
|
|
CA415268007 rs1160433224 |
269 | G>S | No |
ClinGen gnomAD |
|
|
CA415268017 rs1405510846 |
270 | K>R | No |
ClinGen gnomAD |
|
|
rs934598464 CA337197322 |
272 | P>S | No |
ClinGen Ensembl |
|
|
CA415268038 CA10540315 rs755686782 |
273 | N>K | No |
ClinGen ExAC gnomAD |
|
|
CA10540314 rs369378152 |
273 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA415268058 rs1422848790 |
276 | Y>C | No |
ClinGen TOPMed gnomAD |
|
|
CA415268067 rs1374888611 |
277 | L>P | No |
ClinGen gnomAD |
|
|
rs746633698 CA337197338 |
279 | A>V | No |
ClinGen Ensembl |
|
|
rs1441248107 CA415268080 |
280 | Y>H | No |
ClinGen gnomAD |
|
| TCGA novel | 281 | F>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1210914246 CA415268102 |
283 | A>T | No |
ClinGen TOPMed |
|
|
rs1304969433 CA415268105 |
283 | A>V | No |
ClinGen gnomAD |
|
|
CA337197340 rs770761959 |
288 | C>S | No |
ClinGen TOPMed gnomAD |
|
|
rs753563400 CA10540317 |
290 | N>D | No |
ClinGen ExAC gnomAD |
|
|
rs754798475 COSM161361 CA10540318 |
290 | N>S | breast [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs748110682 CA10540320 |
291 | A>G | No |
ClinGen ExAC gnomAD |
|
|
CA415268192 rs894022568 |
296 | L>F | No |
ClinGen TOPMed |
|
|
rs745869992 CA10540323 |
296 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA337197361 rs894022568 |
296 | L>V | No |
ClinGen TOPMed |
|
|
COSM3843874 CA10540325 rs745374692 |
302 | R>Q | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
| TCGA novel | 303 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1303292431 CA415268252 |
305 | Y>N | No |
ClinGen TOPMed |
|
|
CA10540326 rs749565001 |
306 | W>R | No |
ClinGen ExAC gnomAD |
|
|
CA10540327 rs768981366 |
310 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540330 rs767842076 |
313 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs376836037 CA10540328 |
313 | R>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA415268332 rs1215388278 |
316 | I>T | No |
ClinGen Ensembl |
|
|
rs1224309221 CA415268347 |
318 | F>C | No |
ClinGen gnomAD |
|
|
CA337197446 rs1046919874 |
322 | L>V | No |
ClinGen Ensembl |
|
| TCGA novel | 325 | D>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10540333 rs766036345 |
326 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs751147111 CA10540334 COSM1253564 |
327 | R>C | Variant assessed as Somatic; 0.0 impact. oesophagus [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs1433987045 CA415268406 |
327 | R>P | No |
ClinGen gnomAD |
|
|
CA10540336 rs754743441 |
330 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA10540338 rs374473359 |
330 | Q>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10540337 rs199826607 |
330 | Q>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA415268440 rs1275698711 |
332 | A>P | No |
ClinGen gnomAD |
|
|
COSM456968 CA337197479 rs200075966 |
333 | R>C | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
COSM1466321 rs370344133 CA10540341 |
333 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs370344133 CA10540340 |
333 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs756168251 CA10540342 |
334 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs749509959 CA10540344 |
335 | L>Q | No |
ClinGen ExAC gnomAD |
|
|
CA10540343 rs780151060 |
335 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA10540345 rs200876781 |
336 | A>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
CA10540346 rs774635473 |
337 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774635473 CA10540347 |
337 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540348 rs375512067 |
337 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs370636515 COSM3800466 CA10540350 |
338 | A>T | urinary_tract [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA10540351 rs765982317 |
339 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1166381 CA10540353 rs779386501 |
339 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs779386501 CA415268471 |
339 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs779386501 CA10540352 |
339 | R>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA415268469 rs765982317 |
339 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
TCGA novel CA415268483 rs1602728624 |
341 | H>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA Ensembl |
|
CA10540354 rs764731190 |
343 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs752426790 CA10540356 |
343 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA10540355 rs752426790 |
343 | R>P | No |
ClinGen ExAC gnomAD |
|
|
rs757255062 CA10540359 |
344 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780097558 CA10540360 COSM1116875 |
347 | R>C | endometrium [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA10540361 rs780097558 |
347 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748432654 CA10540362 COSM1660029 |
347 | R>H | kidney [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC gnomAD |
|
CA10540363 rs778949621 |
348 | E>K | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 350 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM1116878 rs374706343 CA10540364 |
351 | R>C | ovary endometrium [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA415268543 rs374706343 |
351 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs368374300 CA10540365 |
351 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 352 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs762988621 CA10540366 |
353 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs771505568 CA10540369 |
355 | C>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771505568 CA415268569 |
355 | C>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs866633030 CA337197666 |
356 | P>L | No |
ClinGen Ensembl |
|
|
rs1193925783 CA415268574 |
356 | P>S | No |
ClinGen gnomAD |
|
|
CA337197687 rs944166563 |
357 | A>G | No |
ClinGen TOPMed |
|
|
CA10540370 rs778133759 |
361 | T>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs370666513 CA10540371 |
362 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs370666513 CA415268613 |
362 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA337197724 rs868778152 |
364 | N>K | No |
ClinGen Ensembl |
|
|
rs1351459215 CA415268627 |
364 | N>S | No |
ClinGen TOPMed |
|
|
rs1356454277 CA415268632 |
365 | V>A | No |
ClinGen gnomAD |
|
|
rs374566932 CA10540372 |
365 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA10540374 rs200814649 |
366 | R>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA10540375 rs372169533 |
366 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs200814649 CA10540373 |
366 | R>W | Variant assessed as Somatic; 6.321e-05 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1388194559 CA415268641 |
367 | N>S | No |
ClinGen TOPMed |
|
| TCGA novel | 368 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1319644027 CA415268660 |
370 | L>S | No |
ClinGen TOPMed gnomAD |
|
|
CA10540377 rs761612420 |
371 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs1419443084 CA415268674 |
372 | G>D | No |
ClinGen TOPMed |
|
| TCGA novel | 372 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10540378 rs771135593 |
373 | D>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10540379 rs750380397 |
374 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA415268697 rs1259504880 |
376 | A>G | No |
ClinGen gnomAD |
|
|
rs866664291 CA337197788 |
377 | G>D | No |
ClinGen Ensembl |
|
|
CA10540380 rs754987273 |
378 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
CA10540381 rs779086754 |
379 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1243956072 CA415268719 |
380 | D>G | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA10540382 rs375105847 |
380 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs867872295 CA337197817 |
381 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs758704622 CA10540383 |
381 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA10540384 rs778153451 |
382 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs747308998 CA10540385 |
383 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA10540386 rs367675848 |
384 | G>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10540387 rs367675848 |
384 | G>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA337197879 rs934589886 |
386 | P>A | No |
ClinGen TOPMed |
|
|
CA10540388 rs746436765 |
386 | P>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 389 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs989144884 CA337197880 |
390 | S>C | No |
ClinGen Ensembl |
|
|
rs776809214 CA10540389 |
392 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
CA10540390 rs200132458 |
394 | S>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10540392 rs768242890 |
397 | R>C | No |
ClinGen ExAC gnomAD |
|
|
COSM1556760 rs200441669 CA10540393 |
397 | R>H | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs200441669 CA10540394 |
397 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs906180998 CA337197906 |
398 | K>R | No |
ClinGen TOPMed |
|
|
CA10540396 rs750325375 |
399 | S>A | No |
ClinGen ExAC gnomAD |
|
|
CA337197925 rs1003331674 |
400 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA10540397 rs760732722 |
400 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA10540399 rs775392711 |
402 | T>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs913866571 CA337197940 |
403 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs762651170 CA10540400 |
405 | K>E | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1175281026 CA415268871 |
406 | S>A | No |
ClinGen gnomAD |
|
|
CA415268880 rs1249628497 |
407 | V>D | No |
ClinGen TOPMed gnomAD |
|
|
CA337197950 rs868561933 |
408 | F>S | No |
ClinGen Ensembl |
|
|
rs764372963 CA10540401 |
409 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 411 | S>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM1556756 rs1479836440 CA415268919 |
413 | A>D | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs781719205 CA10540404 |
413 | A>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 414 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs201019474 CA337197980 |
415 | S>C | No |
ClinGen Ensembl |
|
|
CA10540405 rs746360125 |
416 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA415268943 rs1460097329 |
417 | H>P | No |
ClinGen gnomAD |
|
|
CA415268944 rs369656707 |
417 | H>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs780441239 CA10540408 |
419 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA10540409 rs748768797 |
420 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540410 rs768173691 |
421 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA415268985 rs1283942989 |
424 | H>R | No |
ClinGen gnomAD |
|
|
CA415268981 rs1222989275 |
424 | H>Y | No |
ClinGen gnomAD |
|
|
CA10540412 rs773967847 |
426 | K>N | No |
ClinGen ExAC |
|
|
rs764148668 CA337198012 |
427 | P>S | No |
ClinGen 1000Genomes TOPMed |
|
|
rs751456462 CA337198013 |
428 | A>V | No |
ClinGen 1000Genomes |
|
|
CA415269021 rs1199665709 |
430 | G>V | No |
ClinGen gnomAD |
|
|
rs200542186 CA337198015 |
432 | P>S | No |
ClinGen 1000Genomes TOPMed |
|
|
rs1476960884 CA415269044 |
433 | K>N | No |
ClinGen TOPMed |
|
| TCGA novel | 434 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 435 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1194090193 CA415269073 |
438 | Y>C | No |
ClinGen TOPMed |
|
|
CA10540414 rs771845794 |
439 | P>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 440 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1485316930 CA415269091 |
441 | P>A | No |
ClinGen TOPMed |
|
|
CA337198018 rs768332458 |
443 | S>P | No |
ClinGen gnomAD |
|
|
rs766271002 CA10540418 |
446 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs1033847876 CA337198029 |
447 | K>R | No |
ClinGen TOPMed |
|
|
CA337198036 rs377039209 |
448 | A>D | No |
ClinGen ESP TOPMed |
|
|
rs377039209 CA415269136 |
448 | A>G | No |
ClinGen ESP TOPMed |
|
|
CA337198035 rs374023233 |
448 | A>P | No |
ClinGen ESP TOPMed |
|
|
rs374023233 CA337198034 |
448 | A>T | No |
ClinGen ESP TOPMed |
|
|
rs763041518 CA10540421 |
449 | D>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1340399540 CA415269155 |
451 | V>A | No |
ClinGen TOPMed |
|
|
rs1332704667 CA415269166 |
453 | F>L | No |
ClinGen TOPMed |
|
| TCGA novel | 453 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA415269185 rs1373241610 |
455 | G>A | No |
ClinGen gnomAD |
|
|
rs370024017 CA10540422 |
457 | S>P | No |
ClinGen ESP ExAC gnomAD |
|
|
CA337198058 rs374455722 |
459 | H>R | No |
ClinGen ESP TOPMed |
|
|
CA415269234 rs1310170870 |
462 | P>L | No |
ClinGen gnomAD |
|
|
rs1403084993 CA415269236 |
463 | D>H | No |
ClinGen TOPMed |
|
|
rs757621208 CA10540424 |
473 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540425 rs767985802 |
474 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs938114534 CA337198128 |
479 | G>S | No |
ClinGen Ensembl |
|
|
CA415269352 rs1308258094 |
480 | H>R | No |
ClinGen gnomAD |
|
|
CA10540427 rs370262045 |
481 | H>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs749806993 CA10540429 |
481 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA10540428 rs370262045 |
481 | H>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 483 | S>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA337198186 rs1027467005 |
484 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA10540431 rs778458448 |
484 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540432 rs747785501 |
486 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA415269406 rs1458835474 |
489 | K>E | No |
ClinGen TOPMed |
|
|
rs771655329 CA10540433 |
490 | S>P | No |
ClinGen ExAC gnomAD |
|
|
CA415269428 rs1258222932 |
492 | F>S | No |
ClinGen TOPMed |
|
|
rs772742529 CA10540434 |
493 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA10540435 rs62620754 |
493 | S>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 495 | A>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs770656377 CA10540436 |
496 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540437 rs776610833 |
496 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA415269457 rs1341574142 |
497 | S>N | No |
ClinGen TOPMed |
|
|
rs1410742879 CA415269474 |
499 | P>L | No |
ClinGen gnomAD |
|
|
CA415269485 rs764266376 |
501 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540439 rs764266376 |
501 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs199797606 CA337198243 |
502 | T>I | No |
ClinGen 1000Genomes |
|
| VAR_062254 | 502 | T>del | lower fasting circulating triglyceride levels [UniProt] | No | UniProt |
|
CA337198248 rs868254928 |
504 | G>A | No |
ClinGen Ensembl |
|
|
CA337198255 rs868254928 |
504 | G>D | No |
ClinGen Ensembl |
|
|
rs200787393 CA337198261 |
505 | H>P | No |
ClinGen Ensembl |
|
|
CA10540441 rs772097142 |
507 | K>GGGIEGSKTE* | No |
ClinGen ExAC |
|
|
rs1569566969 CA415269547 |
509 | A>V | No |
ClinGen Ensembl |
|
|
rs995790572 CA337198268 |
510 | T>P | No |
ClinGen Ensembl |
|
|
rs998246004 CA337198269 |
511 | S>G | No |
ClinGen TOPMed |
|
|
CA415269569 rs1428757714 |
512 | H>P | No |
ClinGen TOPMed gnomAD |
|
|
CA415269570 rs1428757714 |
512 | H>R | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 514 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs867249936 CA337198289 |
514 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs1388397532 CA415269591 |
515 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1325738390 CA415269612 |
519 | D>N | No |
ClinGen gnomAD |
|
|
CA10540446 rs750644483 |
520 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs767714298 CA10540445 |
520 | Y>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766691601 CA10540448 |
521 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540451 rs779405352 |
522 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 523 | P>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1238236399 CA415269646 |
524 | A>S | No |
ClinGen TOPMed |
|
|
rs752135038 CA10540452 |
526 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA415269665 rs1242117442 |
527 | S>N | No |
ClinGen gnomAD |
|
|
CA10540455 rs777433829 |
527 | S>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 528 | H>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA415269681 rs1602729266 |
529 | P>L | No |
ClinGen Ensembl |
|
|
VAR_062255 rs561077 CA10540457 |
532 | T>A | higher fasting circulating triglyceride levels [UniProt] | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
rs374366140 CA337198335 |
536 | N>S | No |
ClinGen ESP TOPMed |
|
| TCGA novel | 542 | S>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 544 | C>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs917168816 CA337198344 |
545 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs371146604 CA10540461 |
546 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1379288417 CA415269796 |
547 | I>F | No |
ClinGen TOPMed |
|
|
rs1310076466 CA415269808 |
549 | A>P | No |
ClinGen TOPMed |
|
|
CA10540462 rs758699310 |
550 | I>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 551 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10540464 rs760868835 |
552 | H>P | No |
ClinGen ExAC gnomAD |
|
|
CA10540466 rs182874490 |
552 | H>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs760868835 CA10540465 |
552 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs773450160 CA10540463 |
552 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540468 COSM1116900 rs765690309 |
557 | D>N | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
| TCGA novel | 560 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA415269901 rs757882661 |
563 | S>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540470 rs757882661 |
563 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10540472 rs751220560 |
564 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA415269911 rs1211277206 |
565 | S>Y | No |
ClinGen gnomAD |
|
|
CA10540473 rs202029963 |
567 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA415269936 rs1409297036 |
569 | A>G | No |
ClinGen gnomAD |
|
|
CA10540475 rs745595243 |
569 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA10540476 rs769745013 |
571 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1602729404 CA415269963 |
574 | P>T | No |
ClinGen Ensembl |
|
|
rs1478299922 CA415269980 |
576 | A>V | No |
ClinGen gnomAD |
|
|
CA10540477 rs780093398 |
577 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA415269994 rs749275695 |
578 | Q>H | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 580 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10540479 rs371707915 |
583 | T>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs901402971 CA337198468 |
583 | T>S | No |
ClinGen Ensembl |
|
|
CA10540481 rs760818840 |
585 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA415270040 rs1280087906 |
586 | D>H | No |
ClinGen gnomAD |
|
| TCGA novel | 586 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA415270048 rs1352212265 |
587 | L>V | No |
ClinGen gnomAD |
|
|
rs765410234 CA337198494 |
588 | P>S | No |
ClinGen Ensembl |
|
|
CA415270070 rs1282024314 |
590 | P>L | No |
ClinGen gnomAD |
|
|
CA10540483 rs770991631 |
590 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1220659137 CA415270077 |
592 | V>I | No |
ClinGen gnomAD |
|
|
CA415270096 rs1436476672 |
595 | T>A | No |
ClinGen gnomAD |
|
|
rs1204220421 CA415270123 |
599 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
CA415270138 rs1253174231 |
600 | Y>* | No |
ClinGen gnomAD |
|
|
CA337198522 rs866973433 |
601 | H>Q | No |
ClinGen Ensembl |
|
|
CA337198562 rs201645456 |
604 | V>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10540486 rs201645456 |
604 | V>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA415270164 rs1197882347 |
605 | V>I | No |
ClinGen gnomAD |
|
|
CA10540487 VAR_062256 rs13440581 |
606 | I>V | higher fasting circulating triglyceride levels [UniProt] | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
rs1478378985 CA415270190 |
609 | E>K | No |
ClinGen gnomAD |
|
|
CA10540488 rs763439576 |
610 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM755928 rs763647516 CA10540489 |
612 | P>S | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA10540490 rs750977314 |
617 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs756799778 CA10540491 |
618 | V>W | No |
ClinGen ExAC gnomAD |
No associated diseases with Q13585
1 regional properties for Q13585
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 71 - 396 | IPR017452 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled receptor activity | Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
| melatonin receptor activity | Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell-cell signaling | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
| G protein-coupled receptor signaling pathway | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
120 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2YDN1 | GPR161 | G protein-coupled receptor 161 | Bos taurus (Bovine) | PR |
| Q0GBZ5 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Bos taurus (Bovine) | PR |
| Q17QD8 | GPR37L1 | G-protein coupled receptor 37-like 1 | Bos taurus (Bovine) | PR |
| Q8SPN1 | PROKR2 | Prokineticin receptor 2 | Bos taurus (Bovine) | PR |
| P46626 | ADRB3 | Beta-3 adrenergic receptor | Bos taurus (Bovine) | PR |
| O46639 | TRHR | Thyrotropin-releasing hormone receptor | Bos taurus (Bovine) | PR |
| Q8SPN2 | PROKR1 | Prokineticin receptor 1 | Bos taurus (Bovine) | PR |
| B9VR26 | CMLKR1 | Chemerin-like receptor 1 | Bos taurus (Bovine) | PR |
| P18130 | ADRA1A | Alpha-1A adrenergic receptor | Bos taurus (Bovine) | PR |
| B4XF06 | GPR39 | G-protein coupled receptor 39 | Bos taurus (Bovine) | PR |
| O18913 | OPN1LW | Long-wave-sensitive opsin 1 | Felis catus (Cat) (Felis silvestris catus) | PR |
| P28683 | PRA1 | Green-sensitive opsin | Gallus gallus (Chicken) | PR |
| Q9N298 | HTR1A | 5-hydroxytryptamine receptor 1A | Pan troglodytes (Chimpanzee) | PR |
| P08099 | Rh2 | Opsin Rh2 | Drosophila melanogaster (Fruit fly) | PR |
| P06002 | ninaE | Opsin Rh1 | Drosophila melanogaster (Fruit fly) | PR |
| Q4LBB9 | Octbeta2R | Octopamine receptor beta-2R | Drosophila melanogaster (Fruit fly) | PR |
| Q8NFJ6 | PROKR2 | Prokineticin receptor 2 | Homo sapiens (Human) | PR |
| Q9BZJ6 | GPR63 | Probable G-protein coupled receptor 63 | Homo sapiens (Human) | PR |
| Q9H3N8 | HRH4 | Histamine H4 receptor | Homo sapiens (Human) | PR |
| P28336 | NMBR | Neuromedin-B receptor | Homo sapiens (Human) | PR |
| Q9Y5Y3 | GPR45 | Probable G-protein coupled receptor 45 | Homo sapiens (Human) | PR |
| P08913 | ADRA2A | Alpha-2A adrenergic receptor | Homo sapiens (Human) | PR |
| P41597 | CCR2 | C-C chemokine receptor type 2 | Homo sapiens (Human) | PR |
| P51681 | CCR5 | C-C chemokine receptor type 5 | Homo sapiens (Human) | PR |
| Q8TCW9 | PROKR1 | Prokineticin receptor 1 | Homo sapiens (Human) | PR |
| Q99788 | CMKLR1 | Chemerin-like receptor 1 | Homo sapiens (Human) | PR |
| P08908 | HTR1A | 5-hydroxytryptamine receptor 1A | Homo sapiens (Human) | PR |
| P30559 | OXTR | Oxytocin receptor | Homo sapiens (Human) | PR |
| P32239 | CCKBR | Gastrin/cholecystokinin type B receptor | Homo sapiens (Human) | PR |
| O60883 | GPR37L1 | G-protein coupled receptor 37-like 1 | Homo sapiens (Human) | PR |
| Q8TDU9 | RXFP4 | Relaxin-3 receptor 2 | Homo sapiens (Human) | PR |
| P04000 | OPN1LW | Long-wave-sensitive opsin 1 | Homo sapiens (Human) | PR |
| Q6U736 | OPN5 | Opsin-5 | Homo sapiens (Human) | PR |
| P34972 | CNR2 | Cannabinoid receptor 2 | Homo sapiens (Human) | PR |
| P24530 | EDNRB | Endothelin receptor type B | Homo sapiens (Human) | PR |
| P35348 | ADRA1A | Alpha-1A adrenergic receptor | Homo sapiens (Human) | PR |
| Q6W5P4 | NPSR1 | Neuropeptide S receptor | Homo sapiens (Human) | PR |
| O43613 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Homo sapiens (Human) | PR |
| P61073 | CXCR4 | C-X-C chemokine receptor type 4 | Homo sapiens (Human) | PR |
| Q9BXC0 | HCAR1 | Hydroxycarboxylic acid receptor 1 | Homo sapiens (Human) | PR |
| Q15761 | NPY5R | Neuropeptide Y receptor type 5 | Homo sapiens (Human) | PR |
| Q8N6U8 | GPR161 | G-protein coupled receptor 161 | Homo sapiens (Human) | PR |
| Q6DWJ6 | GPR139 | Probable G-protein coupled receptor 139 | Homo sapiens (Human) | PR |
| P21462 | FPR1 | fMet-Leu-Phe receptor | Homo sapiens (Human) | PR |
| P46091 | CMKLR2 | Chemerin-like receptor 2 | Homo sapiens (Human) | PR |
| P32745 | SSTR3 | Somatostatin receptor type 3 | Homo sapiens (Human) | PR |
| P41439 | FOLR3 | Folate receptor gamma | Homo sapiens (Human) | PR |
| P30556 | AGTR1 | Type-1 angiotensin II receptor | Homo sapiens (Human) | PR |
| P35414 | APLNR | Apelin receptor | Homo sapiens (Human) | PR |
| P30411 | BDKRB2 | B2 bradykinin receptor | Homo sapiens (Human) | PR |
| P19973 | Lsp1 | Lymphocyte-specific protein 1 | Mus musculus (Mouse) | PR |
| O54799 | Nmbr | Neuromedin-B receptor | Mus musculus (Mouse) | PR |
| Q64264 | Htr1a | 5-hydroxytryptamine receptor 1A | Mus musculus (Mouse) | PR |
| P51675 | Ccr1 | C-C chemokine receptor type 1 | Mus musculus (Mouse) | PR |
| Q5U431 | Gpr39 | G-protein coupled receptor 39 | Mus musculus (Mouse) | PR |
| Q99JG2 | Gpr37l1 | G-protein coupled receptor 37-like 1 | Mus musculus (Mouse) | PR |
| P97295 | Npy2r | Neuropeptide Y receptor type 2 | Mus musculus (Mouse) | PR |
| O08786 | Cckar | Cholecystokinin receptor type A | Mus musculus (Mouse) | PR |
| P56481 | Cckbr | Gastrin/cholecystokinin type B receptor | Mus musculus (Mouse) | PR |
| P30731 | Gpr83 | G-protein coupled receptor 83 | Mus musculus (Mouse) | PR |
| P97468 | Cmklr1 | Chemerin-like receptor 1 | Mus musculus (Mouse) | PR |
| P21761 | Trhr | Thyrotropin-releasing hormone receptor | Mus musculus (Mouse) | PR |
| Q5QD16 | Taar3 | Trace amine-associated receptor 3 | Mus musculus (Mouse) | PR |
| P97292 | Hrh2 | Histamine H2 receptor | Mus musculus (Mouse) | PR |
| Q9EQQ3 | Gpr63 | Probable G-protein coupled receptor 63 | Mus musculus (Mouse) | PR |
| Q924H0 | Npffr2 | Neuropeptide FF receptor 2 | Mus musculus (Mouse) | PR |
| P34971 | Adrb1 | Beta-1 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q91ZY2 | Hrh4 | Histamine H4 receptor | Mus musculus (Mouse) | PR |
| O88416 | Gpr33 | Probable G-protein coupled receptor 33 | Mus musculus (Mouse) | PR |
| Q8K087 | Cmklr2 | Chemerin-like receptor 2 | Mus musculus (Mouse) | PR |
| P70658 | Cxcr4 | C-X-C chemokine receptor type 4 | Mus musculus (Mouse) | PR |
| Q9WV08 | Aplnr | Apelin receptor | Mus musculus (Mouse) | PR |
| P97718 | Adra1a | Alpha-1A adrenergic receptor | Mus musculus (Mouse) | PR |
| Q8BZP8 | Npsr1 | Neuropeptide S receptor | Mus musculus (Mouse) | PR |
| Q8K458 | Prokr2 | Prokineticin receptor 2 | Mus musculus (Mouse) | PR |
| P58308 | Hcrtr2 | Orexin receptor type 2 | Mus musculus (Mouse) | PR |
| Q7TQP3 | Gpr119 | Glucose-dependent insulinotropic receptor | Mus musculus (Mouse) | PR |
| Q8BGE9 | Rxfp3 | Relaxin-3 receptor 1 | Mus musculus (Mouse) | PR |
| Q6VZZ7 | Opn5 | Opsin-5 | Mus musculus (Mouse) | PR |
| Q8CIM5 | Gpr84 | G-protein coupled receptor 84 | Mus musculus (Mouse) | PR |
| P25962 | Adrb3 | Beta-3 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q80UC8 | Gpr139 | Probable G-protein coupled receptor 139 | Mus musculus (Mouse) | PR |
| P0C5I1 | Gpr25 | Probable G-protein coupled receptor 25 | Mus musculus (Mouse) | PR |
| P47936 | Cnr2 | Cannabinoid receptor 2 | Mus musculus (Mouse) | PR |
| Q5QD13 | Taar6 | Trace amine-associated receptor 6 | Mus musculus (Mouse) | PR |
| P35846 | Folr1 | Folate receptor alpha | Mus musculus (Mouse) | PR |
| P58307 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Mus musculus (Mouse) | PR |
| Q8C131 | Hcar1 | Hydroxycarboxylic acid receptor 1 | Mus musculus (Mouse) | PR |
| Q9EQQ4 | Gpr45 | Probable G-protein coupled receptor 45 | Mus musculus (Mouse) | PR |
| B2RPY5 | Gpr161 | G-protein coupled receptor 161 | Mus musculus (Mouse) | PR |
| Q764M9 | CXCR4 | C-X-C chemokine receptor type 4 | Sus scrofa (Pig) | PR |
| Q9EQD2 | Npffr2 | Neuropeptide FF receptor 2 | Rattus norvegicus (Rat) | PR |
| O08565 | Cxcr4 | C-X-C chemokine receptor type 4 | Rattus norvegicus (Rat) | PR |
| Q01717 | Trhr | Thyrotropin-releasing hormone receptor | Rattus norvegicus (Rat) | PR |
| P30936 | Sstr3 | Somatostatin receptor type 3 | Rattus norvegicus (Rat) | PR |
| Q9JHG3 | Aplnr | Apelin receptor | Rattus norvegicus (Rat) | PR |
| P43140 | Adra1a | Alpha-1A adrenergic receptor | Rattus norvegicus (Rat) | PR |
| P19327 | Htr1a | 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Rat) | PR |
| P56719 | Hcrtr2 | Orexin receptor type 2 | Rattus norvegicus (Rat) | PR |
| P28564 | Htr1b | 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Rat) | PR |
| P56718 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Rattus norvegicus (Rat) | PR |
| P28647 | Adora3 | Adenosine receptor A3 | Rattus norvegicus (Rat) | PR |
| P25102 | Hrh2 | Histamine H2 receptor | Rattus norvegicus (Rat) | PR |
| P23944 | Adra1d | Alpha-1D adrenergic receptor | Rattus norvegicus (Rat) | PR |
| Q8R415 | Prokr2 | Prokineticin receptor 2 | Rattus norvegicus (Rat) | PR |
| Q5QD24 | Taar3 | Trace amine-associated receptor 3 | Rattus norvegicus (Rat) | PR |
| P0C0W8 | Gpr139 | Probable G-protein coupled receptor 139 | Rattus norvegicus (Rat) | PR |
| P35370 | Oprl1 | Nociceptin receptor | Rattus norvegicus (Rat) | PR |
| P46090 | Cmklr2 | Chemerin-like receptor 2 | Rattus norvegicus (Rat) | PR |
| O97664 | CMKLR2 | Chemerin-like receptor 2 | Macaca mulatta (Rhesus macaque) | PR |
| O97666 | APLNR | Apelin receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q56H79 | NPSR1 | Neuropeptide S receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q18904 | npr-8 | Probable G-protein coupled receptor npr-8 | Caenorhabditis elegans | PR |
| Q09388 | gar-2 | Muscarinic acetylcholine receptor gar-2 | Caenorhabditis elegans | PR |
| B3DM66 | gpr161 | G-protein coupled receptor 161 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q9W6A6 | opn1mw4 | Green-sensitive opsin-4 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q9W6A5 | opn1mw1 | Green-sensitive opsin-1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYM7 | opn1mw3 | Green-sensitive opsin-3 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYN0 | opn1lw2 | Red-sensitive opsin-2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q90X46 | gpr161 | G-protein coupled receptor 161 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGPTLAVPTP | YGCIGCKLPQ | PEYPPALIIF | MFCAMVITIV | VDLIGNSMVI | LAVTKNKKLR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NSGNIFVVSL | SVADMLVAIY | PYPLMLHAMS | IGGWDLSQLQ | CQMVGFITGL | SVVGSIFNIV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AIAINRYCYI | CHSLQYERIF | SVRNTCIYLV | ITWIMTVLAV | LPNMYIGTIE | YDPRTYTCIF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NYLNNPVFTV | TIVCIHFVLP | LLIVGFCYVR | IWTKVLAARD | PAGQNPDNQL | AEVRNFLTMF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VIFLLFAVCW | CPINVLTVLV | AVSPKEMAGK | IPNWLYLAAY | FIAYFNSCLN | AVIYGLLNEN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FRREYWTIFH | AMRHPIIFFS | GLISDIREMQ | EARTLARARA | HARDQAREQD | RAHACPAVEE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TPMNVRNVPL | PGDAAAGHPD | RASGHPKPHS | RSSSAYRKSA | STHHKSVFSH | SKAASGHLKP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VSGHSKPASG | HPKSATVYPK | PASVHFKADS | VHFKGDSVHF | KPDSVHFKPA | SSNPKPITGH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| HVSAGSHSKS | AFSAATSHPK | PTTGHIKPAT | SHAEPTTADY | PKPATTSHPK | PTAADNPELS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ASHCPEIPAI | AHPVSDDSDL | PESASSPAAG | PTKPAASQLE | SDTIADLPDP | TVVTTSTNDY |
| 610 | |||||
| HDVVVIDVED | DPDEMAV |