Q15761
PR
Gene name |
NPY5R (NPYR5) |
Protein name |
Neuropeptide Y receptor type 5 |
Names |
NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:4889 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q15761
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q15761-F1 | Predicted | AlphaFoldDB |
329 variants for Q15761
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs1285433837 CA358665097 |
3 | L>* | No |
ClinGen gnomAD |
|
|
CA110084893 rs913841290 |
4 | E>A | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 6 | D>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3126688 COSM1052845 rs780119025 |
6 | D>N | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs780119025 CA358665159 |
6 | D>Y | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 7 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1560869723 CA358665210 |
7 | E>G | No |
ClinGen Ensembl |
|
|
CA358665194 rs1466540804 |
7 | E>K | No |
ClinGen gnomAD |
|
|
rs1352555589 CA358665249 |
8 | Y>* | No |
ClinGen TOPMed |
|
|
CA358665268 rs1243144668 |
9 | Y>F | No |
ClinGen gnomAD |
|
|
rs75269811 CA3126692 |
10 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3126693 rs78861810 |
11 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 11 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1274241658 CA358665401 |
13 | L>H | No |
ClinGen TOPMed |
|
|
CA3126696 rs201640301 |
14 | A>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs745630054 CA3126695 |
14 | A>P | No |
ClinGen ExAC gnomAD |
|
|
rs745630054 CA358665412 |
14 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA358665423 rs201640301 |
14 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA358665454 COSM1052846 rs1320973552 |
16 | E>D | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs760331232 CA3126698 |
19 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA3126699 rs768056385 |
19 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA3126700 rs776148718 |
20 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 21 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM1179262 CA3126701 rs375176738 |
23 | R>Q | Variant assessed as Somatic; 9.25e-05 impact. central_nervous_system prostate [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA358665604 rs777746508 |
23 | R>W | No |
ClinGen gnomAD |
|
|
CA110084896 rs945935121 |
24 | N>K | No |
ClinGen Ensembl |
|
| TCGA novel | 24 | N>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1286076048 CA358665697 |
28 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1286076048 CA358665695 |
28 | P>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1255751658 CA358665725 |
30 | W>* | No |
ClinGen gnomAD |
|
|
rs1229461731 CA358665714 |
30 | W>* | No |
ClinGen gnomAD |
|
|
rs1255751658 CA358665731 |
30 | W>C | No |
ClinGen gnomAD |
|
|
rs773762046 CA3126703 |
32 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA358665794 rs1336242896 |
33 | Y>H | No |
ClinGen TOPMed |
|
|
CA358665821 rs1202734438 |
34 | K>E | No |
ClinGen gnomAD |
|
|
rs200912302 CA3126705 |
34 | K>T | No |
ClinGen ESP ExAC gnomAD |
|
|
CA3126706 rs751738838 |
35 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1042954323 CA110084897 |
36 | S>R | No |
ClinGen Ensembl |
|
|
CA358665888 rs1180015621 |
36 | S>T | No |
ClinGen gnomAD |
|
|
CA110084898 rs3967767 |
38 | D>N | No |
ClinGen Ensembl |
|
|
rs755174120 CA3126707 |
38 | D>V | No |
ClinGen ExAC gnomAD |
|
|
rs1473033532 CA358666016 |
41 | Q>* | No |
ClinGen gnomAD |
|
|
CA3126708 rs767555011 |
45 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA3126709 rs571795802 |
46 | G>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1560870025 CA358666232 |
49 | T>I | No |
ClinGen Ensembl |
|
|
CA3126710 rs757222561 |
51 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM586555 CA358666267 rs757222561 |
51 | V>L | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1560870044 CA358666300 |
52 | S>T | No |
ClinGen Ensembl |
|
|
rs1560870069 CA358666313 |
53 | L>I | No |
ClinGen Ensembl |
|
|
rs1408761353 CA358666345 |
54 | L>P | No |
ClinGen gnomAD |
|
|
rs1410025043 CA358666428 COSM230045 |
57 | M>I | NS [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA110084900 rs537633153 |
57 | M>V | No |
ClinGen 1000Genomes |
|
|
rs1300119834 CA358666470 |
59 | N>S | No |
ClinGen gnomAD |
|
|
rs1235806334 CA358666492 |
60 | L>P | No |
ClinGen gnomAD |
|
|
CA358666486 rs1310829404 |
60 | L>V | No |
ClinGen gnomAD |
|
|
rs779831413 CA3126715 |
62 | I>S | No |
ClinGen ExAC gnomAD |
|
|
rs1479105407 CA358666594 |
65 | A>G | No |
ClinGen TOPMed |
|
|
rs372200526 CA3126716 |
66 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs372200526 CA358666603 |
66 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
COSM1695187 CA110084902 rs867560945 |
67 | M>I | NS Variant assessed as Somatic; impact. skin [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
|
CA3126718 rs375564689 |
67 | M>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358666704 rs1560870197 |
69 | K>T | No |
ClinGen Ensembl |
|
|
CA3126719 rs747640202 |
70 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA3126720 rs80086880 |
70 | R>H | Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA3126722 rs147087846 |
71 | N>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3126721 rs147087846 |
71 | N>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA358666762 rs1177963605 |
71 | N>S | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 73 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3126723 rs552707275 COSM3660972 |
75 | T>M | liver [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
| TCGA novel | 76 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358666997 rs1429770436 |
80 | I>M | No |
ClinGen gnomAD |
|
|
rs767751082 CA3126726 |
80 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs759746938 CA3126725 |
80 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752819658 CA3126727 |
81 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA110084903 rs1024920404 |
82 | N>H | No |
ClinGen Ensembl |
|
|
rs574392131 CA3126728 |
82 | N>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1226794730 CA358667086 |
84 | A>V | No |
ClinGen gnomAD |
|
|
rs1277344384 CA358667100 |
85 | F>S | No |
ClinGen TOPMed gnomAD |
|
|
CA110084905 rs758297007 |
87 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3126731 rs758297007 |
87 | D>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1560870378 CA358667194 |
88 | I>S | No |
ClinGen Ensembl |
|
|
CA3126733 rs536920158 CA358667222 |
89 | L>F | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs962869909 CA110084906 |
92 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
| TCGA novel | 94 | C>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1253366451 COSM1309864 CA358667358 |
95 | S>L | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1361463122 CA358667381 |
96 | P>L | No |
ClinGen Ensembl |
|
|
rs747764021 CA3126737 |
100 | T>R | No |
ClinGen ExAC gnomAD |
|
|
rs79962221 CA110084907 |
101 | S>F | No |
ClinGen Ensembl |
|
|
rs772794090 CA3126739 |
102 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs769434625 COSM1197659 CA3126738 |
102 | V>F | lung [Cosmic] | No |
ClinGen cosmic curated ExAC |
|
rs749822591 CA3126740 |
103 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs774621918 CA3126742 |
104 | L>M | No |
ClinGen ExAC gnomAD |
|
|
CA110084908 rs996930289 |
105 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
CA3126743 rs759920239 |
107 | W>R | No |
ClinGen ExAC gnomAD |
|
|
COSM1052847 rs1300454687 CA358667639 |
108 | M>V | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs79693996 CA110084909 |
110 | G>C | No |
ClinGen TOPMed |
|
|
rs1227871662 CA358667708 |
110 | G>D | No |
ClinGen gnomAD |
|
|
CA358667695 rs79693996 |
110 | G>S | No |
ClinGen TOPMed |
|
|
CA110084910 rs757149914 |
113 | M>I | No |
ClinGen Ensembl |
|
| TCGA novel | 114 | C>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM1328621 rs775716946 CA3126746 |
115 | H>R | ovary Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA358667861 rs1460871627 |
116 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs963890058 CA110084911 |
117 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1183201514 CA358667947 |
118 | P>S | No |
ClinGen TOPMed |
|
|
rs760817083 CA3126747 |
120 | L>R | No |
ClinGen ExAC gnomAD |
|
|
CA3126748 rs138294096 |
122 | C>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358668057 rs1464281154 |
123 | V>A | No |
ClinGen gnomAD |
|
|
rs753900977 CA3126749 |
128 | S>P | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 131 | I>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs766307943 COSM3601579 CA3126751 |
134 | S>L | Variant assessed as Somatic; impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs762864161 CA3126750 |
134 | S>P | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 134 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358668314 rs1424998085 |
137 | I>T | No |
ClinGen gnomAD |
|
|
rs751405239 CA3126752 |
137 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs866941603 CA110084912 |
142 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA3126755 rs752411470 |
143 | I>R | No |
ClinGen ExAC gnomAD |
|
|
rs752411470 CA358668475 |
143 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA358668521 rs1456043093 |
145 | H>L | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 145 | H>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA110084913 rs966644785 |
145 | H>Y | No |
ClinGen TOPMed |
|
|
rs868709530 CA110084914 |
146 | P>L | No |
ClinGen Ensembl |
|
|
rs545198380 CA3126756 |
147 | I>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA358668567 rs1322149205 |
147 | I>T | No |
ClinGen TOPMed |
|
|
CA3126757 rs777496266 |
149 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358668641 rs1226772780 |
151 | L>V | No |
ClinGen TOPMed |
|
|
CA358668690 rs771394300 |
153 | A>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3126759 rs771394300 |
153 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779493820 CA3126760 |
155 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA358668773 rs1228908294 |
156 | G>D | No |
ClinGen gnomAD |
|
|
CA358668808 rs75420635 |
157 | Y>* | No |
ClinGen gnomAD |
|
|
CA3126761 rs746318939 |
160 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs1328210005 CA358668880 |
161 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
COSM1052850 rs1226404367 CA358668896 |
161 | A>V | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA110084916 rs770112406 |
163 | V>L | No |
ClinGen Ensembl |
|
|
rs772425843 CA3126762 |
164 | W>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA358668985 rs1578959695 |
165 | T>A | No |
ClinGen Ensembl |
|
|
CA358669022 rs1447553606 |
167 | G>S | No |
ClinGen gnomAD |
|
|
rs1375306670 CA358669053 |
168 | F>V | No |
ClinGen TOPMed |
|
|
rs987157395 CA110084918 |
179 | S>R | No |
ClinGen TOPMed gnomAD |
|
|
CA358669374 rs1209373978 |
180 | L>I | No |
ClinGen gnomAD |
|
|
CA3126763 rs775770157 |
181 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA358669392 rs1578959742 |
181 | V>L | No |
ClinGen Ensembl |
|
|
CA110084920 rs749777768 |
183 | L>R | No |
ClinGen TOPMed gnomAD |
|
|
CA3126765 rs768861008 |
185 | E>A | No |
ClinGen ExAC gnomAD |
|
|
rs761929596 CA3126767 |
186 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs143395004 CA3126770 |
190 | A>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358669600 rs143395004 |
190 | A>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs751519258 CA3126769 |
190 | A>T | No |
ClinGen ExAC gnomAD |
|
|
COSM1428367 CA358669601 rs143395004 |
190 | A>V | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA358669624 rs1282801486 |
191 | L>S | No |
ClinGen gnomAD |
|
|
rs1415543008 CA358669649 |
192 | L>P | No |
ClinGen TOPMed gnomAD |
|
|
CA110084921 rs866624816 |
196 | Y>H | No |
ClinGen Ensembl |
|
|
rs1307479576 CA358669776 |
198 | C>R | No |
ClinGen gnomAD |
|
|
rs767480870 CA3126771 |
199 | V>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 200 | E>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358669848 rs1468085366 |
202 | W>* | No |
ClinGen Ensembl |
|
|
CA3126772 rs368949528 |
202 | W>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3126773 rs755873415 |
203 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs777549230 CA3126774 |
203 | P>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 206 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA110084922 rs747501364 |
207 | Y>H | No |
ClinGen Ensembl |
|
|
CA358669938 rs1578959893 |
208 | R>G | No |
ClinGen Ensembl |
|
|
CA3126777 rs778215574 |
209 | I>F | No |
ClinGen ExAC gnomAD |
|
|
rs1219624915 CA358669964 |
209 | I>T | No |
ClinGen gnomAD |
|
|
CA3126778 rs778215574 |
209 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs758891916 CA3126779 |
210 | A>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 212 | T>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1481765650 CA358670076 |
216 | L>F | No |
ClinGen gnomAD |
|
|
rs1211818515 CA358670082 |
217 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs1233041247 CA358670183 |
223 | P>L | No |
ClinGen gnomAD |
|
|
CA3126782 rs768914000 COSM162977 |
226 | C>S | NS [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1260588964 CA358670263 |
229 | V>I | No |
ClinGen gnomAD |
|
|
CA3126785 rs769931328 |
230 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs773152847 CA3126786 |
231 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA3126790 rs775477312 |
233 | S>I | No |
ClinGen ExAC gnomAD |
|
|
CA3126789 rs775477312 |
233 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1435571351 CA358670507 |
242 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA110084924 rs990663503 |
246 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs75295713 CA3126791 |
247 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 247 | N>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs753530484 CA3126792 |
249 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3126793 rs74402296 |
249 | L>R | No |
ClinGen ExAC gnomAD |
|
|
rs764856338 CA3126794 |
250 | E>A | No |
ClinGen ExAC gnomAD |
|
|
rs764856338 CA358670673 |
250 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA358670724 rs1339471999 |
252 | N>D | No |
ClinGen gnomAD |
|
| TCGA novel | 253 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358670768 rs1242374765 |
253 | E>D | No |
ClinGen TOPMed |
|
|
rs749896146 CA3126795 |
253 | E>K | No |
ClinGen ExAC gnomAD |
|
|
COSM1671412 rs1273350964 CA358670797 |
254 | M>I | skin [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs1450669111 CA358670821 |
255 | I>F | No |
ClinGen gnomAD |
|
|
CA358670956 rs1351647760 |
262 | S>P | No |
ClinGen TOPMed |
|
|
rs747465135 CA3126798 |
263 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761809480 CA110084925 |
263 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA358671000 rs1560871222 |
265 | S>G | No |
ClinGen Ensembl |
|
|
CA358671011 CA358671012 rs1388795364 |
265 | S>R | No |
ClinGen TOPMed gnomAD |
|
|
rs755342331 CA3126799 |
266 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA358671080 rs1442649327 |
269 | V>G | No |
ClinGen gnomAD |
|
|
rs1436281778 CA358671070 |
269 | V>L | No |
ClinGen TOPMed |
|
|
rs748462009 CA3126801 |
270 | K>I | No |
ClinGen ExAC gnomAD |
|
|
rs1578960250 CA358671091 |
270 | K>N | No |
ClinGen Ensembl |
|
|
rs1403786378 CA358671094 |
271 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA358671112 rs1396444039 |
272 | S>P | No |
ClinGen gnomAD |
|
|
rs76980175 CA3126805 |
273 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358671127 rs749361936 |
273 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA110084926 rs76980175 |
273 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3126804 rs749361936 |
273 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358671128 rs76980175 |
273 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs544008119 CA3126806 |
274 | S>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs544008119 CA3126807 |
274 | S>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA110084927 rs767742585 |
275 | H>R | No |
ClinGen gnomAD |
|
|
rs868605309 CA110084928 |
277 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs763961294 CA3126808 |
277 | W>C | No |
ClinGen ExAC gnomAD |
|
|
COSM322088 CA358671206 rs886454677 |
278 | S>N | lung [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA110084929 rs886454677 |
278 | S>T | No |
ClinGen gnomAD |
|
| TCGA novel | 281 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3126810 rs138572457 |
283 | K>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 285 | H>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358671347 rs1246797027 |
287 | R>K | No |
ClinGen TOPMed gnomAD |
|
| rs750456846 | 288 | R>missing | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1466622380 CA358671359 |
288 | R>K | No |
ClinGen TOPMed gnomAD |
|
|
CA3126812 rs764763745 |
289 | Y>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs141683280 CA3126814 |
290 | S>I | No |
ClinGen ESP ExAC gnomAD |
|
|
CA358671421 rs1463962104 |
291 | K>R | No |
ClinGen gnomAD |
|
|
rs140627140 CA3126815 |
292 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA3126816 rs752075333 |
292 | K>M | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 292 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs140627140 COSM107354 CA110084930 |
292 | K>Q | skin [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA3126817 rs146231711 |
293 | T>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA3126818 rs376406619 |
295 | C>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA110084931 rs996373111 |
295 | C>R | No |
ClinGen Ensembl |
|
|
CA358671984 rs1560871448 |
297 | L>F | No |
ClinGen Ensembl |
|
|
rs74555158 CA110084932 |
300 | P>A | No |
ClinGen Ensembl |
|
|
rs371075570 CA3126822 |
303 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs777885404 CA3126821 |
303 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3126823 rs771135789 |
305 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs188410293 RCV000906135 CA3126824 |
306 | E>K | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
rs149950875 CA3126825 |
307 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358672055 rs761031263 |
308 | H>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1332515732 CA358672061 |
309 | S>C | No |
ClinGen gnomAD |
|
|
rs1266592632 CA358672083 |
313 | P>A | No |
ClinGen gnomAD |
|
|
rs768469643 CA3126826 |
316 | F>S | No |
ClinGen ExAC gnomAD |
|
|
rs1206265892 CA358672115 |
317 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
rs776528732 CA3126827 |
318 | S>C | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 318 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 320 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358672147 rs1189705818 |
322 | Q>R | No |
ClinGen gnomAD |
|
|
rs769582817 CA3126829 |
323 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs762534938 CA3126831 |
327 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs369457022 CA3126832 COSM402529 |
331 | P>Q | lung [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
| TCGA novel | 333 | V>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1409523955 CA358672216 |
333 | V>I | No |
ClinGen gnomAD |
|
|
CA358672226 rs1578960622 |
334 | P>L | No |
ClinGen Ensembl |
|
|
CA358672236 rs1466152331 |
336 | C>Y | No |
ClinGen TOPMed |
|
|
rs144160203 CA3126833 |
338 | E>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1401324849 CA358672260 |
339 | I>M | No |
ClinGen gnomAD |
|
|
CA110084935 rs967450484 |
339 | I>R | No |
ClinGen Ensembl |
|
|
CA110084934 rs898716663 |
339 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
CA3126835 rs767891015 |
344 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs753203361 CA3126836 |
345 | S>P | No |
ClinGen ExAC gnomAD |
|
|
CA3126837 rs756470118 |
346 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM586546 CA358672305 rs1408874008 |
346 | D>N | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA358672314 rs1424004129 |
347 | V>A | No |
ClinGen TOPMed |
|
|
CA358672310 rs1339137117 |
347 | V>I | No |
ClinGen gnomAD |
|
|
rs866593868 CA110084938 |
351 | R>K | No |
ClinGen gnomAD |
|
|
CA358672360 rs1343482307 |
353 | K>N | No |
ClinGen TOPMed gnomAD |
|
|
CA3126839 rs374003048 COSM3428308 |
354 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs757537567 CA3126840 |
354 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757537567 CA3126841 |
354 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358672364 rs757537567 |
354 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1482745269 CA358672375 |
356 | V>A | No |
ClinGen gnomAD |
|
|
CA358672384 rs1254369809 |
358 | R>G | No |
ClinGen TOPMed |
|
| TCGA novel | 361 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 362 | R>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 363 | S>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358672420 rs1252854319 |
363 | S>T | No |
ClinGen gnomAD |
|
|
CA358672427 COSM1217758 rs1415844038 |
364 | R>* | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs768685790 CA3126844 |
364 | R>L | No |
ClinGen ExAC gnomAD |
|
|
rs768685790 CA358672428 |
364 | R>P | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs768685790 CA3126843 COSM1052857 |
364 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA3126845 rs748078024 |
368 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs1217256429 CA358672492 |
374 | I>T | No |
ClinGen TOPMed |
|
| TCGA novel | 375 | L>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA110084940 rs750432652 |
376 | V>A | No |
ClinGen Ensembl |
|
|
TCGA novel CA358672508 rs1175394539 |
377 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen gnomAD |
|
rs769491321 COSM1671414 CA3126846 |
378 | A>V | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs1578960875 CA358672526 |
380 | S>C | No |
ClinGen Ensembl |
|
|
rs762662577 CA3126848 |
380 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1375069357 CA358672539 |
381 | W>* | No |
ClinGen gnomAD |
|
|
CA358672548 rs1403665464 |
382 | M>I | No |
ClinGen TOPMed |
|
| TCGA novel | 383 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs770541555 CA3126849 |
384 | L>P | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 385 | H>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1485111795 CA358672569 |
386 | L>I | No |
ClinGen TOPMed gnomAD |
|
|
rs868723897 CA358672583 |
388 | H>N | No |
ClinGen gnomAD |
|
|
rs868723897 CA110084942 |
388 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1341557653 CA358672593 |
389 | V>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA358672596 rs1203027015 |
390 | V>I | No |
ClinGen gnomAD |
|
|
CA358672607 rs1172542968 |
391 | T>I | No |
ClinGen TOPMed |
|
|
CA358672608 rs1578960973 |
392 | D>N | No |
ClinGen Ensembl |
|
| TCGA novel | 392 | D>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 397 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358672666 rs767017396 |
399 | S>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs767017396 CA3126852 |
399 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs753153581 CA358672681 |
401 | R>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 403 | F>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3126854 rs559921705 |
404 | K>N | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1395541749 CA358672712 |
406 | V>M | No |
ClinGen gnomAD |
|
|
rs754248718 CA3126856 COSM2151547 |
409 | I>V | Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA |
|
rs148699921 CA3126857 |
410 | C>R | No |
ClinGen ESP ExAC TOPMed |
|
|
CA3126858 rs765532392 |
411 | H>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs750607555 CA3126859 |
413 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA3126860 rs758438196 |
414 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA110084944 rs959274781 |
415 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
CA3126861 rs780114554 |
416 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA110084945 rs79616232 |
418 | C>Y | No |
ClinGen Ensembl |
|
|
rs765114666 CA3126865 |
422 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1365093167 CA358672829 |
423 | I>V | No |
ClinGen gnomAD |
|
|
rs1308113148 CA358672870 |
429 | N>Y | No |
ClinGen gnomAD |
|
|
rs77793484 CA110084946 |
432 | I>V | No |
ClinGen Ensembl |
|
|
rs745461284 CA3126870 |
434 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM3946137 CA110084947 rs917746483 |
435 | D>Y | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
CA110084948 rs762882119 |
438 | S>P | No |
ClinGen Ensembl |
|
|
rs775048398 CA3126872 |
440 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358672950 rs1341899591 |
441 | H>R | No |
ClinGen TOPMed |
|
|
rs761149591 CA3126873 |
441 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs764662778 CA3126874 |
442 | C>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1428538603 CA358672979 |
445 | M>I | No |
ClinGen gnomAD |
|
|
CA3126875 rs548797512 |
445 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA110084949 rs983239091 |
445 | M>V | No |
ClinGen TOPMed |
No associated diseases with Q15761
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| neuron projection | A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| synapse | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| neuropeptide binding | Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators). |
| neuropeptide receptor activity | Combining with a neuropeptide to initiate a change in cell activity. |
| neuropeptide Y receptor activity | Combining with neuropeptide Y to initiate a change in cell activity. |
| pancreatic polypeptide receptor activity | Combining with pancreatic polypeptide PP to initiate a change in cell activity. |
| peptide YY receptor activity | Combining with gut peptide YY to initiate a change in cell activity. |
14 GO annotations of biological process
| Name | Definition |
|---|---|
| aging | A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700). |
| cardiac left ventricle morphogenesis | The process in which the left cardiac ventricle is generated and organized. |
| chemical synaptic transmission | The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. |
| eating behavior | The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue. |
| G protein-coupled receptor signaling pathway | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
| generation of ovulation cycle rhythm | The process which controls the timing of the type of sexual cycle seen in female mammals. |
| negative regulation of acute inflammatory response to antigenic stimulus | Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. |
| negative regulation of apoptotic process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. |
| negative regulation of glutamate secretion | Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate. |
| negative regulation of synaptic transmission, GABAergic | Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). |
| outflow tract morphogenesis | The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. |
| positive regulation of acute inflammatory response | Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response. |
| positive regulation of ERK1 and ERK2 cascade | Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. |
| positive regulation of smooth muscle cell proliferation | Any process that activates or increases the rate or extent of smooth muscle cell proliferation. |
120 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2YDN1 | GPR161 | G protein-coupled receptor 161 | Bos taurus (Bovine) | PR |
| Q0GBZ5 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Bos taurus (Bovine) | PR |
| Q17QD8 | GPR37L1 | G-protein coupled receptor 37-like 1 | Bos taurus (Bovine) | PR |
| Q8SPN1 | PROKR2 | Prokineticin receptor 2 | Bos taurus (Bovine) | PR |
| P46626 | ADRB3 | Beta-3 adrenergic receptor | Bos taurus (Bovine) | PR |
| O46639 | TRHR | Thyrotropin-releasing hormone receptor | Bos taurus (Bovine) | PR |
| Q8SPN2 | PROKR1 | Prokineticin receptor 1 | Bos taurus (Bovine) | PR |
| B9VR26 | CMLKR1 | Chemerin-like receptor 1 | Bos taurus (Bovine) | PR |
| P18130 | ADRA1A | Alpha-1A adrenergic receptor | Bos taurus (Bovine) | PR |
| B4XF06 | GPR39 | G-protein coupled receptor 39 | Bos taurus (Bovine) | PR |
| O18913 | OPN1LW | Long-wave-sensitive opsin 1 | Felis catus (Cat) (Felis silvestris catus) | PR |
| P28683 | PRA1 | Green-sensitive opsin | Gallus gallus (Chicken) | PR |
| Q9N298 | HTR1A | 5-hydroxytryptamine receptor 1A | Pan troglodytes (Chimpanzee) | PR |
| O62729 | NPY5R | Neuropeptide Y receptor type 5 | Canis lupus familiaris (Dog) (Canis familiaris) | PR |
| P08099 | Rh2 | Opsin Rh2 | Drosophila melanogaster (Fruit fly) | PR |
| P06002 | ninaE | Opsin Rh1 | Drosophila melanogaster (Fruit fly) | PR |
| Q4LBB9 | Octbeta2R | Octopamine receptor beta-2R | Drosophila melanogaster (Fruit fly) | PR |
| Q8NFJ6 | PROKR2 | Prokineticin receptor 2 | Homo sapiens (Human) | PR |
| Q13585 | GPR50 | Melatonin-related receptor | Homo sapiens (Human) | PR |
| Q9BZJ6 | GPR63 | Probable G-protein coupled receptor 63 | Homo sapiens (Human) | PR |
| Q9H3N8 | HRH4 | Histamine H4 receptor | Homo sapiens (Human) | PR |
| P28336 | NMBR | Neuromedin-B receptor | Homo sapiens (Human) | PR |
| Q9Y5Y3 | GPR45 | Probable G-protein coupled receptor 45 | Homo sapiens (Human) | PR |
| P08913 | ADRA2A | Alpha-2A adrenergic receptor | Homo sapiens (Human) | PR |
| P41597 | CCR2 | C-C chemokine receptor type 2 | Homo sapiens (Human) | PR |
| P51681 | CCR5 | C-C chemokine receptor type 5 | Homo sapiens (Human) | PR |
| Q8TCW9 | PROKR1 | Prokineticin receptor 1 | Homo sapiens (Human) | PR |
| Q99788 | CMKLR1 | Chemerin-like receptor 1 | Homo sapiens (Human) | PR |
| P08908 | HTR1A | 5-hydroxytryptamine receptor 1A | Homo sapiens (Human) | PR |
| P30559 | OXTR | Oxytocin receptor | Homo sapiens (Human) | PR |
| P32239 | CCKBR | Gastrin/cholecystokinin type B receptor | Homo sapiens (Human) | PR |
| O60883 | GPR37L1 | G-protein coupled receptor 37-like 1 | Homo sapiens (Human) | PR |
| Q8TDU9 | RXFP4 | Relaxin-3 receptor 2 | Homo sapiens (Human) | PR |
| P04000 | OPN1LW | Long-wave-sensitive opsin 1 | Homo sapiens (Human) | PR |
| Q6U736 | OPN5 | Opsin-5 | Homo sapiens (Human) | PR |
| P34972 | CNR2 | Cannabinoid receptor 2 | Homo sapiens (Human) | PR |
| P24530 | EDNRB | Endothelin receptor type B | Homo sapiens (Human) | PR |
| P35348 | ADRA1A | Alpha-1A adrenergic receptor | Homo sapiens (Human) | PR |
| Q6W5P4 | NPSR1 | Neuropeptide S receptor | Homo sapiens (Human) | PR |
| O43613 | HCRTR1 | Orexin/Hypocretin receptor type 1 | Homo sapiens (Human) | PR |
| P61073 | CXCR4 | C-X-C chemokine receptor type 4 | Homo sapiens (Human) | PR |
| Q9BXC0 | HCAR1 | Hydroxycarboxylic acid receptor 1 | Homo sapiens (Human) | PR |
| P30556 | AGTR1 | Type-1 angiotensin II receptor | Homo sapiens (Human) | PR |
| Q8N6U8 | GPR161 | G-protein coupled receptor 161 | Homo sapiens (Human) | PR |
| Q6DWJ6 | GPR139 | Probable G-protein coupled receptor 139 | Homo sapiens (Human) | PR |
| P21462 | FPR1 | fMet-Leu-Phe receptor | Homo sapiens (Human) | PR |
| P35414 | APLNR | Apelin receptor | Homo sapiens (Human) | PR |
| P46091 | CMKLR2 | Chemerin-like receptor 2 | Homo sapiens (Human) | PR |
| P32745 | SSTR3 | Somatostatin receptor type 3 | Homo sapiens (Human) | PR |
| P41439 | FOLR3 | Folate receptor gamma | Homo sapiens (Human) | PR |
| P19973 | Lsp1 | Lymphocyte-specific protein 1 | Mus musculus (Mouse) | PR |
| O54799 | Nmbr | Neuromedin-B receptor | Mus musculus (Mouse) | PR |
| Q64264 | Htr1a | 5-hydroxytryptamine receptor 1A | Mus musculus (Mouse) | PR |
| P51675 | Ccr1 | C-C chemokine receptor type 1 | Mus musculus (Mouse) | PR |
| Q5U431 | Gpr39 | G-protein coupled receptor 39 | Mus musculus (Mouse) | PR |
| Q99JG2 | Gpr37l1 | G-protein coupled receptor 37-like 1 | Mus musculus (Mouse) | PR |
| P97295 | Npy2r | Neuropeptide Y receptor type 2 | Mus musculus (Mouse) | PR |
| O08786 | Cckar | Cholecystokinin receptor type A | Mus musculus (Mouse) | PR |
| P56481 | Cckbr | Gastrin/cholecystokinin type B receptor | Mus musculus (Mouse) | PR |
| P30731 | Gpr83 | G-protein coupled receptor 83 | Mus musculus (Mouse) | PR |
| P97468 | Cmklr1 | Chemerin-like receptor 1 | Mus musculus (Mouse) | PR |
| P21761 | Trhr | Thyrotropin-releasing hormone receptor | Mus musculus (Mouse) | PR |
| Q5QD16 | Taar3 | Trace amine-associated receptor 3 | Mus musculus (Mouse) | PR |
| P97292 | Hrh2 | Histamine H2 receptor | Mus musculus (Mouse) | PR |
| Q9EQQ3 | Gpr63 | Probable G-protein coupled receptor 63 | Mus musculus (Mouse) | PR |
| Q924H0 | Npffr2 | Neuropeptide FF receptor 2 | Mus musculus (Mouse) | PR |
| P34971 | Adrb1 | Beta-1 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q91ZY2 | Hrh4 | Histamine H4 receptor | Mus musculus (Mouse) | PR |
| O88416 | Gpr33 | Probable G-protein coupled receptor 33 | Mus musculus (Mouse) | PR |
| Q8K087 | Cmklr2 | Chemerin-like receptor 2 | Mus musculus (Mouse) | PR |
| P70658 | Cxcr4 | C-X-C chemokine receptor type 4 | Mus musculus (Mouse) | PR |
| Q9WV08 | Aplnr | Apelin receptor | Mus musculus (Mouse) | PR |
| P97718 | Adra1a | Alpha-1A adrenergic receptor | Mus musculus (Mouse) | PR |
| Q8BZP8 | Npsr1 | Neuropeptide S receptor | Mus musculus (Mouse) | PR |
| Q8K458 | Prokr2 | Prokineticin receptor 2 | Mus musculus (Mouse) | PR |
| P58308 | Hcrtr2 | Orexin receptor type 2 | Mus musculus (Mouse) | PR |
| Q7TQP3 | Gpr119 | Glucose-dependent insulinotropic receptor | Mus musculus (Mouse) | PR |
| Q8BGE9 | Rxfp3 | Relaxin-3 receptor 1 | Mus musculus (Mouse) | PR |
| Q6VZZ7 | Opn5 | Opsin-5 | Mus musculus (Mouse) | PR |
| Q8CIM5 | Gpr84 | G-protein coupled receptor 84 | Mus musculus (Mouse) | PR |
| P25962 | Adrb3 | Beta-3 adrenergic receptor | Mus musculus (Mouse) | PR |
| Q80UC8 | Gpr139 | Probable G-protein coupled receptor 139 | Mus musculus (Mouse) | PR |
| P0C5I1 | Gpr25 | Probable G-protein coupled receptor 25 | Mus musculus (Mouse) | PR |
| P47936 | Cnr2 | Cannabinoid receptor 2 | Mus musculus (Mouse) | PR |
| Q5QD13 | Taar6 | Trace amine-associated receptor 6 | Mus musculus (Mouse) | PR |
| P35846 | Folr1 | Folate receptor alpha | Mus musculus (Mouse) | PR |
| P58307 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Mus musculus (Mouse) | PR |
| Q8C131 | Hcar1 | Hydroxycarboxylic acid receptor 1 | Mus musculus (Mouse) | PR |
| Q9EQQ4 | Gpr45 | Probable G-protein coupled receptor 45 | Mus musculus (Mouse) | PR |
| B2RPY5 | Gpr161 | G-protein coupled receptor 161 | Mus musculus (Mouse) | PR |
| Q764M9 | CXCR4 | C-X-C chemokine receptor type 4 | Sus scrofa (Pig) | PR |
| Q9EQD2 | Npffr2 | Neuropeptide FF receptor 2 | Rattus norvegicus (Rat) | PR |
| O08565 | Cxcr4 | C-X-C chemokine receptor type 4 | Rattus norvegicus (Rat) | PR |
| Q01717 | Trhr | Thyrotropin-releasing hormone receptor | Rattus norvegicus (Rat) | PR |
| P30936 | Sstr3 | Somatostatin receptor type 3 | Rattus norvegicus (Rat) | PR |
| Q9JHG3 | Aplnr | Apelin receptor | Rattus norvegicus (Rat) | PR |
| P43140 | Adra1a | Alpha-1A adrenergic receptor | Rattus norvegicus (Rat) | PR |
| P19327 | Htr1a | 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Rat) | PR |
| P56719 | Hcrtr2 | Orexin receptor type 2 | Rattus norvegicus (Rat) | PR |
| P28564 | Htr1b | 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Rat) | PR |
| P56718 | Hcrtr1 | Orexin/Hypocretin receptor type 1 | Rattus norvegicus (Rat) | PR |
| P28647 | Adora3 | Adenosine receptor A3 | Rattus norvegicus (Rat) | PR |
| P25102 | Hrh2 | Histamine H2 receptor | Rattus norvegicus (Rat) | PR |
| P23944 | Adra1d | Alpha-1D adrenergic receptor | Rattus norvegicus (Rat) | PR |
| Q8R415 | Prokr2 | Prokineticin receptor 2 | Rattus norvegicus (Rat) | PR |
| Q5QD24 | Taar3 | Trace amine-associated receptor 3 | Rattus norvegicus (Rat) | PR |
| P0C0W8 | Gpr139 | Probable G-protein coupled receptor 139 | Rattus norvegicus (Rat) | PR |
| P35370 | Oprl1 | Nociceptin receptor | Rattus norvegicus (Rat) | PR |
| P46090 | Cmklr2 | Chemerin-like receptor 2 | Rattus norvegicus (Rat) | PR |
| O97664 | CMKLR2 | Chemerin-like receptor 2 | Macaca mulatta (Rhesus macaque) | PR |
| O97666 | APLNR | Apelin receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q56H79 | NPSR1 | Neuropeptide S receptor | Macaca mulatta (Rhesus macaque) | PR |
| Q09388 | gar-2 | Muscarinic acetylcholine receptor gar-2 | Caenorhabditis elegans | PR |
| Q18904 | npr-8 | Probable G-protein coupled receptor npr-8 | Caenorhabditis elegans | PR |
| B3DM66 | gpr161 | G-protein coupled receptor 161 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q9W6A6 | opn1mw4 | Green-sensitive opsin-4 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q9W6A5 | opn1mw1 | Green-sensitive opsin-1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYM7 | opn1mw3 | Green-sensitive opsin-3 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q8AYN0 | opn1lw2 | Red-sensitive opsin-2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q90X46 | gpr161 | G-protein coupled receptor 161 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDLELDEYYN | KTLATENNTA | ATRNSDFPVW | DDYKSSVDDL | QYFLIGLYTF | VSLLGFMGNL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LILMALMKKR | NQKTTVNFLI | GNLAFSDILV | VLFCSPFTLT | SVLLDQWMFG | KVMCHIMPFL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QCVSVLVSTL | ILISIAIVRY | HMIKHPISNN | LTANHGYFLI | ATVWTLGFAI | CSPLPVFHSL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VELQETFGSA | LLSSRYLCVE | SWPSDSYRIA | FTISLLLVQY | ILPLVCLTVS | HTSVCRSISC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GLSNKENRLE | ENEMINLTLH | PSKKSGPQVK | LSGSHKWSYS | FIKKHRRRYS | KKTACVLPAP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ERPSQENHSR | ILPENFGSVR | SQLSSSSKFI | PGVPTCFEIK | PEENSDVHEL | RVKRSVTRIK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KRSRSVFYRL | TILILVFAVS | WMPLHLFHVV | TDFNDNLISN | RHFKLVYCIC | HLLGMMSCCL |
| 430 | 440 | ||||
| NPILYGFLNN | GIKADLVSLI | HCLHM |