Q9D8M4
Gene name |
Rpl7l1 |
Protein name |
60S ribosomal protein L7-like 1 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:66229 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9D8M4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9D8M4-F1 | Predicted | AlphaFoldDB |
9 variants for Q9D8M4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389435820 | 25 | Q>H | No | EVA | |
| rs3389462838 | 59 | S>Y | No | EVA | |
| rs3389461599 | 60 | W>C | No | EVA | |
| rs46208401 | 68 | R>H | No | EVA | |
| rs3389470920 | 139 | T>S | No | EVA | |
| rs3389459341 | 140 | W>D | No | EVA | |
| rs3389469990 | 141 | G>R | No | EVA | |
| rs221367344 | 175 | E>G | No | EVA | |
| rs243142956 | 176 | H>R | No | EVA |
No associated diseases with Q9D8M4
4 regional properties for Q9D8M4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribosomal protein L30, N-terminal | 13 - 83 | IPR012988 |
| domain | Ribosomal protein L30, ferredoxin-like fold domain | 88 - 138 | IPR016082 |
| conserved_site | Ribosomal protein L30, conserved site | 106 - 138 | IPR018038 |
| domain | Ribosomal protein L7, eukaryotic/archaeal | 87 - 246 | IPR035808 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| cytosolic large ribosomal subunit | The large subunit of a ribosome located in the cytosol. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| blastocyst formation | The initial formation of a blastocyst from a solid ball of cells known as a morula. |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P05737 | RPL7A | 60S ribosomal protein L7-A | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q58DT1 | RPL7 | 60S ribosomal protein L7 | Bos taurus (Bovine) | PR |
| Q6W5P4 | NPSR1 | Neuropeptide S receptor | Homo sapiens (Human) | PR |
| P18124 | RPL7 | 60S ribosomal protein L7 | Homo sapiens (Human) | PR |
| Q6DKI1 | RPL7L1 | 60S ribosomal protein L7-like 1 | Homo sapiens (Human) | PR |
| Q8BZP8 | Npsr1 | Neuropeptide S receptor | Mus musculus (Mouse) | PR |
| P14148 | Rpl7 | 60S ribosomal protein L7 | Mus musculus (Mouse) | PR |
| A5GFQ0 | RPL7L1 | 60S ribosomal protein L7-like 1 | Sus scrofa (Pig) | PR |
| P05426 | Rpl7 | 60S ribosomal protein L7 | Rattus norvegicus (Rat) | PR |
| Q56H79 | NPSR1 | Neuropeptide S receptor | Macaca mulatta (Rhesus macaque) | PR |
| P60039 | RPL7C | 60S ribosomal protein L7-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEEGERKKI | PLVPENLLKK | RKAYQALKAT | QAKQALLAKR | ERKGKQFRFR | RLESFVHDSW |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RQQRDKVRVQ | RLEVKPRALE | VPDKHPLAFV | IRMERIEGVS | LLVKSTIMKL | GLKKLFSGVF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VKVTPQSVRM | LRTVEPYVTW | GFPNLKSVRE | LILKRGQAKI | NNKTVPLTDN | TVIEEHLGRF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GVICLEDLIH | EIAFPGKHFQ | EVSSFLCPFL | LSVARHATRN | RVGFRKEMGS | PGYRGDRINQ |
| LIRQLN |