Q58DT1
Gene name |
RPL7 |
Protein name |
60S ribosomal protein L7 |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:514966 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q58DT1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q58DT1-F1 | Predicted | AlphaFoldDB |
59 variants for Q58DT1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs432607156 | 35 | K>M | No | EVA | |
| rs473697897 | 39 | Q>R | No | EVA | |
| rs473658942 | 45 | A>P | No | EVA | |
| rs453663009 | 46 | R>S | No | EVA | |
| rs436569724 | 48 | K>E | No | EVA | |
| rs474459585 | 52 | E>D | No | EVA | |
| rs457426417 | 54 | A>P | No | EVA | |
| rs437238814 | 55 | K>N | No | EVA | |
| rs465301262 | 56 | H>D | No | EVA | |
| rs445167928 | 56 | H>R | No | EVA | |
| rs434760330 | 57 | Y>* | No | EVA | |
| rs465883756 | 58 | H>D | No | EVA | |
| rs465883756 | 58 | H>N | No | EVA | |
| rs449124228 | 58 | H>P | No | EVA | |
| rs480441607 | 60 | E>K | No | EVA | |
| rs477931364 | 61 | Y>* | No | EVA | |
| rs469929039 | 61 | Y>N | No | EVA | |
| rs449872659 | 61 | Y>S | No | EVA | |
| rs457846903 | 62 | R>M | No | EVA | |
| rs440826896 | 62 | R>S | No | EVA | |
| rs478633353 | 63 | Q>K | No | EVA | |
| rs443137104 | 65 | Y>* | No | EVA | |
| rs460032852 | 65 | Y>N | No | EVA | |
| rs474530216 | 66 | R>S | No | EVA | |
| rs457421873 | 67 | T>P | No | EVA | |
| rs443838348 | 70 | R>G | No | EVA | |
| rs471671328 | 71 | M>L | No | EVA | |
| rs451722593 | 71 | M>R | No | EVA | |
| rs434723456 | 72 | A>V | No | EVA | |
| rs466046400 | 76 | R>* | No | EVA | |
| rs466046400 | 76 | R>G | No | EVA | |
| rs455732443 | 78 | A>P | No | EVA | |
| rs478033058 | 85 | A>E | No | EVA | |
| rs478594098 | 91 | F>V | No | EVA | |
| rs441606843 | 97 | G>D | No | EVA | |
| rs442148707 | 98 | I>S | No | EVA | |
| rs476741647 | 100 | G>V | No | EVA | |
| rs462908799 | 101 | V>G | No | EVA | |
| rs439652879 | 104 | K>M | No | EVA | |
| rs470847210 | 108 | V>G | No | EVA | |
| rs454056794 | 114 | L>R | No | EVA | |
| rs474869754 | 119 | N>D | No | EVA | |
| rs454531607 | 120 | G>C | No | EVA | |
| rs437649554 | 122 | F>L | No | EVA | |
| rs451959444 | 124 | K>N | No | EVA | |
| rs469075136 | 124 | K>T | No | EVA | |
| rs447939953 | 139 | Y>F | No | EVA | |
| rs479241953 | 140 | I>T | No | EVA | |
| rs452800478 | 144 | Y>S | No | EVA | |
| rs434228271 | 145 | P>R | No | EVA | |
| rs448631455 | 149 | S>F | No | EVA | |
| rs483292874 | 150 | V>A | No | EVA | |
| rs446205652 | 151 | N>D | No | EVA | |
| rs460493987 | 152 | E>A | No | EVA | |
| rs477387487 | 152 | E>Q | No | EVA | |
| rs461241770 | 155 | Y>C | No | EVA | |
| rs481329791 | 155 | Y>H | No | EVA | |
| rs452081205 | 167 | I>S | No | EVA | |
| rs472912186 | 173 | A>T | No | EVA |
No associated diseases with Q58DT1
1 regional properties for Q58DT1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| active_site | Adenosine/AMP deaminase active site | 658 - 664 | IPR006650 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosolic large ribosomal subunit | The large subunit of a ribosome located in the cytosol. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P05737 | RPL7A | 60S ribosomal protein L7-A | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q6W5P4 | NPSR1 | Neuropeptide S receptor | Homo sapiens (Human) | PR |
| Q6DKI1 | RPL7L1 | 60S ribosomal protein L7-like 1 | Homo sapiens (Human) | PR |
| P18124 | RPL7 | 60S ribosomal protein L7 | Homo sapiens (Human) | PR |
| Q8BZP8 | Npsr1 | Neuropeptide S receptor | Mus musculus (Mouse) | PR |
| Q9D8M4 | Rpl7l1 | 60S ribosomal protein L7-like 1 | Mus musculus (Mouse) | PR |
| P14148 | Rpl7 | 60S ribosomal protein L7 | Mus musculus (Mouse) | PR |
| A5GFQ0 | RPL7L1 | 60S ribosomal protein L7-like 1 | Sus scrofa (Pig) | PR |
| P05426 | Rpl7 | 60S ribosomal protein L7 | Rattus norvegicus (Rat) | PR |
| Q56H79 | NPSR1 | Neuropeptide S receptor | Macaca mulatta (Rhesus macaque) | PR |
| P60039 | RPL7C | 60S ribosomal protein L7-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEGAEEKKKK | VPAVPETLKK | KRKNFAELKI | KRLRKKFAQK | MLRKARRKLI | YEKAKHYHKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YRQMYRTEIR | MARMARKAGN | FYVPAEPKLA | FVIRIRGING | VSPKVRKVLQ | LLRLRQIFNG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TFVKLNKASI | NMLRIVEPYI | AWGYPNLKSV | NELIYKRGYG | KINKKRIALT | DNALIARSLG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KYGIICMEDL | IHEIYTVGKR | FKEANNFLWP | FKLSSPRGGM | KKKTTHFVEG | GDAGNREDQI |
| NRLIRRMN |