Q9SAE4

PR
Gene name
CYP71B29 (At1g13100, F3F19.12)
Protein name
Cytochrome P450 71B29
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G13100
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-71 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SAE4

Entry ID Method Resolution Chain Position Source
AF-Q9SAE4-F1 Predicted AlphaFoldDB

70 variants for Q9SAE4

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01044994 10 L>F No 1000Genomes
ENSVATH00021111 37 F>I No 1000Genomes
tmp_1_4464093_C_T,G 37 F>L No 1000Genomes
ENSVATH04568434 44 L>I No 1000Genomes
tmp_1_4464151_G_T 57 G>W No 1000Genomes
ENSVATH04568435 58 P>A No 1000Genomes
tmp_1_4464166_C_T 62 L>F No 1000Genomes
tmp_1_4464170_G_A 63 R>H No 1000Genomes
ENSVATH07511734 74 S>Y No 1000Genomes
ENSVATH11117619 94 E>A No 1000Genomes
tmp_1_4464287_C_G 102 S>C No 1000Genomes
ENSVATH04568436 107 D>N No 1000Genomes
tmp_1_4464347_A_T 122 K>M No 1000Genomes
ENSVATH04568439 128 L>F No 1000Genomes
tmp_1_4464382_C_A 134 H>N No 1000Genomes
ENSVATH11117620 140 I>T No 1000Genomes
ENSVATH11117621 142 E>K No 1000Genomes
tmp_1_4464412_G_A 144 E>K No 1000Genomes
ENSVATH04568440 153 T>I No 1000Genomes
tmp_1_4464447_G_T 155 L>F No 1000Genomes
tmp_1_4464457_C_T 159 R>* No 1000Genomes
ENSVATH11117622 163 N>K No 1000Genomes
tmp_1_4464503_G_A 174 S>N No 1000Genomes
ENSVATH04568443 184 N>D No 1000Genomes
ENSVATH11117685 192 D>N No 1000Genomes
ENSVATH11117686 194 N>D No 1000Genomes
ENSVATH13889011 211 M>I No 1000Genomes
ENSVATH11117687 219 G>E No 1000Genomes
tmp_1_4464692_T_C 237 V>A No 1000Genomes
tmp_1_4464716_T_G 245 F>C No 1000Genomes
ENSVATH04568445 245 F>V No 1000Genomes
ENSVATH11117689 246 Q>E No 1000Genomes
tmp_1_4464739_C_A 253 L>I No 1000Genomes
ENSVATH04568446 258 K>R No 1000Genomes
ENSVATH04568447 260 A>E No 1000Genomes
ENSVATH04568448 261 D>E No 1000Genomes
tmp_1_4464770_C_A 263 S>Y No 1000Genomes
ENSVATH00021113 269 V>M No 1000Genomes
tmp_1_4464791_T_A 270 I>N No 1000Genomes
ENSVATH04568450 273 I>M No 1000Genomes
tmp_1_4464824_A_G 281 D>G No 1000Genomes
ENSVATH04568451 282 S>C No 1000Genomes
tmp_1_4464841_A_G 287 T>A No 1000Genomes
ENSVATH04568452 291 K>R No 1000Genomes
ENSVATH04568457 299 L>I No 1000Genomes
ENSVATH04568458 313 I>V No 1000Genomes
ENSVATH04568459 320 R>P No 1000Genomes
ENSVATH04568460 321 K>E No 1000Genomes
ENSVATH04568461 328 E>D No 1000Genomes
ENSVATH04568462 333 T>K No 1000Genomes
ENSVATH04568464 335 G>E No 1000Genomes
ENSVATH04568465 347 T>I No 1000Genomes
ENSVATH13889013 387 A>V No 1000Genomes
ENSVATH04568469 389 T>N No 1000Genomes
ENSVATH11117692 391 I>M No 1000Genomes
tmp_1_4465254_G_A 397 A>T No 1000Genomes
ENSVATH04568471 399 A>T No 1000Genomes
tmp_1_4465266_G_A 401 D>N No 1000Genomes
ENSVATH04568473 402 P>L No 1000Genomes
ENSVATH04568472 402 P>S No 1000Genomes
ENSVATH04568474 403 K>E No 1000Genomes
tmp_1_4465321_G_A 419 S>N No 1000Genomes
tmp_1_4465350_G_A 429 E>K No 1000Genomes
tmp_1_4465354_T_A 430 L>Q No 1000Genomes
ENSVATH04568477 432 P>R No 1000Genomes
tmp_1_4465398_A_T 445 M>L No 1000Genomes
ENSVATH11117693 447 I>T No 1000Genomes
tmp_1_4465454_G_C 463 W>C No 1000Genomes
ENSVATH04568479 479 G>R No 1000Genomes
ENSVATH00021114 482 V>L No 1000Genomes

No associated diseases with Q9SAE4

1 regional properties for Q9SAE4

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 439 - 448 IPR017972

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

53 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O18963 CYP2E1 Cytochrome P450 2E1 Bos taurus (Bovine) PR
Q0IIF9 CYP2U1 Cytochrome P450 2U1 Bos taurus (Bovine) PR
P12394 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Gallus gallus (Chicken) PR
Q8HYN1 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Pan troglodytes (Chimpanzee) PR
Q95078 Cyp18a1 Cytochrome P450 18a1 Drosophila melanogaster (Fruit fly) PR
P10632 CYP2C8 Cytochrome P450 2C8 Homo sapiens (Human) PR
P33260 CYP2C18 Cytochrome P450 2C18 Homo sapiens (Human) PR
Q7Z449 CYP2U1 Cytochrome P450 2U1 Homo sapiens (Human) PR
P05093 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Homo sapiens (Human) PR
P05177 CYP1A2 Cytochrome P450 1A2 Homo sapiens (Human) PR
P05181 CYP2E1 Cytochrome P450 2E1 Homo sapiens (Human) PR
P51589 CYP2J2 Cytochrome P450 2J2 Homo sapiens (Human) PR
Q9CX98 Cyp2u1 Cytochrome P450 2U1 Mus musculus (Mouse) PR
O54749 Cyp2j5 Cytochrome P450 2J5 Mus musculus (Mouse) PR
O54750 Cyp2j6 Cytochrome P450 2J6 Mus musculus (Mouse) PR
P24456 Cyp2d10 Cytochrome P450 2D10 Mus musculus (Mouse) PR
P24457 Cyp2d11 Cytochrome P450 2D11 Mus musculus (Mouse) PR
P27786 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Mus musculus (Mouse) PR
Q9D816 Cyp2c55 Cytochrome P450 2C55 Mus musculus (Mouse) PR
P79383 CYP2E1 Cytochrome P450 2E1 Sus scrofa (Pig) PR
P10633 Cyp2d1 Cytochrome P450 2D1 Rattus norvegicus (Rat) PR
P11715 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Rattus norvegicus (Rat) PR
P12939 Cyp2d10 Cytochrome P450 2D10 Rattus norvegicus (Rat) PR
P20814 Cyp2c13 Cytochrome P450 2C13, male-specific Rattus norvegicus (Rat) PR
O35293 Cyp2f2 Cytochrome P450 2F2 Rattus norvegicus (Rat) PR
P05182 Cyp2e1 Cytochrome P450 2E1 Rattus norvegicus (Rat) PR
P12938 Cyp2d3 Cytochrome P450 2D3 Rattus norvegicus (Rat) PR
P24470 Cyp2c23 Cytochrome P450 2C23 Rattus norvegicus (Rat) PR
P33273 Cyp2c55 Cytochrome P450 2C55 Rattus norvegicus (Rat) PR
P05179 Cyp2c7 Cytochrome P450 2C7 Rattus norvegicus (Rat) PR
Q8HYM9 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Macaca mulatta (Rhesus macaque) PR
A3A871 CYP71Z6 Ent-isokaurene C2/C3-hydroxylase Oryza sativa subsp japonica (Rice) PR
Q6YV88 CYP71Z7 Ent-cassadiene hydroxylase Oryza sativa subsp japonica (Rice) PR
Q7X7X4 CYP99A2 Cytochrome P450 99A2 Oryza sativa subsp japonica (Rice) PR
O48957 CYP99A1 Cytochrome P450 CYP99A1 Sorghum bicolor (Sorghum) (Sorghum vulgare) PR
Q42797 CYP73A11 Trans-cinnamate 4-monooxygenase Glycine max (Soybean) (Glycine hispida) PR
Q9XHC6 CYP93E1 Beta-amyrin 24-hydroxylase Glycine max (Soybean) (Glycine hispida) PR
O81971 CYP71D9 Cytochrome P450 71D9 Glycine max (Soybean) (Glycine hispida) PR
O48922 CYP98A2 Cytochrome P450 98A2 Glycine max (Soybean) (Glycine hispida) PR
Q949U1 CYP79F1 Dihomomethionine N-hydroxylase Arabidopsis thaliana (Mouse-ear cress) PR
Q9CA61 CYP98A8 Cytochrome P450 98A8 Arabidopsis thaliana (Mouse-ear cress) PR
O64636 CYP76C1 Cytochrome P450 76C1 Arabidopsis thaliana (Mouse-ear cress) PR
O64638 CYP76C3 Cytochrome P450 76C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SRQ1 CYP89A9 Cytochrome P450 89A9 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LVD2 CYP71B10 Cytochrome P450 71B10 Arabidopsis thaliana (Mouse-ear cress) PR
O49340 CYP71A12 Cytochrome P450 71A12 Arabidopsis thaliana (Mouse-ear cress) PR
P58049 CYP71B11 Cytochrome P450 71B11 Arabidopsis thaliana (Mouse-ear cress) PR
P58050 CYP71B13 Cytochrome P450 71B13 Arabidopsis thaliana (Mouse-ear cress) PR
Q96514 CYP71B7 Cytochrome P450 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM0 CYP71B23 Cytochrome P450 71B23 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM6 CYP71B17 Cytochrome P450 71B17 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM7 CYP71B16 Cytochrome P450 71B16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZU07 CYP71B12 Cytochrome P450 71B12 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAIILCFLIL LPLILIFLKK LKHSKWKLPP GPPKLPFIGN LHQLQELPPR NLNHKYGPVI
70 80 90 100 110 120
LLRFGFVPLV VISSKEAAEE VLKIHDLECC SRPETAGTRK ISYNFKDIGF APYGEEWKAM
130 140 150 160 170 180
RKLSVVELFT AKKHQYFRSI REEENDLLVK KLTELALTRS PVNLKKTLFT LVGSIVCRIG
190 200 210 220 230 240
FGFNLHECEF IDENSISDLV DKSEILEMTS MFSDFFPGGI GRFIDWISGQ NKRFDNVFSD
250 260 270 280 290 300
LDTFFQNILD YHLKPGRKVA DSSDIIDVVI NMIKKQEKDG DSFKLTTDHL KGMISDIFLA
310 320 330 340 350 360
GVSTSASTLI WAITELVRNR KVMKKVQEEI RTTLGDKKER ITEQDLTNLH YFKLVVKEIF
370 380 390 400 410 420
RLHPAVPFLL PRETLSHVKI QGYDIPAKTQ IMINVYAIAR DPKLWTNPDE FNPDRFLDSS
430 440 450 460 470 480
IDYKGLNFEL LPFGSGRRIC PGMTMGITLV EFALLNLLYF FDWGLPEKEE ADKIITGNGV
AVGLVQVLLH