Q9LTM7

PR
Gene name
CYP71B16 (At3g26150, MTC11.5)
Protein name
Cytochrome P450 71B16
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G26150
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

304-374 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LTM7

Entry ID Method Resolution Chain Position Source
AF-Q9LTM7-F1 Predicted AlphaFoldDB

88 variants for Q9LTM7

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH14015357 7 C>S No 1000Genomes
ENSVATH14015357 7 C>Y No 1000Genomes
ENSVATH02207639 12 T>S No 1000Genomes
tmp_3_9567174_T_G 13 L>F No 1000Genomes
tmp_3_9567163_A_T 17 I>N No 1000Genomes
tmp_3_9567161_A_T 18 F>I No 1000Genomes
tmp_3_9567158_C_G,A 19 V>F No 1000Genomes
tmp_3_9567158_C_G,A 19 V>L No 1000Genomes
tmp_3_9567154_A_C 20 V>G No 1000Genomes
tmp_3_9567152_T_A 21 K>* No 1000Genomes
tmp_3_9567150_C_G 21 K>N No 1000Genomes
tmp_3_9567151_T_C 21 K>R No 1000Genomes
ENSVATH02207637 26 S>C No 1000Genomes
ENSVATH02207637 26 S>F No 1000Genomes
tmp_3_9567129_C_A 28 W>C No 1000Genomes
ENSVATH00351547 29 D>N No 1000Genomes
ENSVATH02207636 44 H>D No 1000Genomes
tmp_3_9567049_T_C 55 Q>R No 1000Genomes
ENSVATH05920615 56 R>H No 1000Genomes
tmp_3_9567034_C_T 60 R>K No 1000Genomes
tmp_3_9567006_A_T 69 F>L No 1000Genomes
tmp_3_9567002_A_G 71 F>L No 1000Genomes
ENSVATH05920613 87 L>F No 1000Genomes
tmp_3_9566943_A_C 90 H>Q No 1000Genomes
ENSVATH11002140 96 T>N No 1000Genomes
ENSVATH00351546 103 S>T No 1000Genomes
tmp_3_9566819_C_T 132 E>K No 1000Genomes
tmp_3_9566806_A_G 136 F>S No 1000Genomes
ENSVATH14015356 147 E>V No 1000Genomes
ENSVATH05920611 152 L>F No 1000Genomes
ENSVATH11002137 154 V>I No 1000Genomes
ENSVATH02207630 158 T>S No 1000Genomes
tmp_3_9566719_G_A 165 P>L No 1000Genomes
ENSVATH00351544 165 P>S No 1000Genomes
tmp_3_9566710_T_C 168 D>G No 1000Genomes
ENSVATH02207628 172 S>T No 1000Genomes
ENSVATH02207627 176 L>I No 1000Genomes
tmp_3_9566659_G_C 185 A>G No 1000Genomes
ENSVATH11002114 192 D>N No 1000Genomes
ENSVATH05920608 208 T>I No 1000Genomes
ENSVATH05920606 224 A>S No 1000Genomes
ENSVATH05920606 224 A>T No 1000Genomes
tmp_3_9566537_G_A 226 L>F No 1000Genomes
ENSVATH05920605 228 W>S No 1000Genomes
ENSVATH05920604 232 W>L No 1000Genomes
tmp_3_9566509_C_G 235 G>A No 1000Genomes
ENSVATH00351542 238 R>K No 1000Genomes
ENSVATH02207623 253 R>H No 1000Genomes
ENSVATH14015294 259 S>L No 1000Genomes
tmp_3_9566435_C_T 260 D>N No 1000Genomes
ENSVATH11002113 273 V>I No 1000Genomes
ENSVATH02207621 279 H>R No 1000Genomes
ENSVATH02207620 282 G>D No 1000Genomes
ENSVATH02207619 288 R>K No 1000Genomes
tmp_3_9566339_C_A 292 D>Y No 1000Genomes
ENSVATH05920596 306 I>V No 1000Genomes
tmp_3_9566157_T_G 327 M>L No 1000Genomes
ENSVATH02207617 329 N>K No 1000Genomes
ENSVATH05920595 330 V>A No 1000Genomes
tmp_3_9566126_C_T 337 S>N No 1000Genomes
ENSVATH00351541 337 S>R No 1000Genomes
tmp_3_9566088_G_C 350 L>V No 1000Genomes
tmp_3_9566082_T_A 352 K>* No 1000Genomes
tmp_3_9566073_A_G 355 F>L No 1000Genomes
tmp_3_9566022_G_C 372 L>V No 1000Genomes
ENSVATH11002106 382 I>N No 1000Genomes
ENSVATH11002105 392 K>R No 1000Genomes
ENSVATH02207616 400 W>C No 1000Genomes
ENSVATH00351540 407 T>K No 1000Genomes
tmp_3_9565913_A_G 408 L>P No 1000Genomes
ENSVATH11002034 414 E>D No 1000Genomes
ENSVATH05920590 419 R>G No 1000Genomes
tmp_3_9565866_G_T 424 P>T No 1000Genomes
ENSVATH05920589 425 V>I No 1000Genomes
ENSVATH14015292 432 F>V No 1000Genomes
tmp_3_9565814_C_A 441 R>L No 1000Genomes
ENSVATH11002033 443 I>M No 1000Genomes
ENSVATH11002032 453 I>K No 1000Genomes
ENSVATH05920583 454 V>M No 1000Genomes
ENSVATH05920582 460 N>S No 1000Genomes
ENSVATH05920580 466 D>N No 1000Genomes
tmp_3_9565734_T_C 468 R>G No 1000Genomes
tmp_3_9565728_G_A 470 P>S No 1000Genomes
tmp_3_9565721_C_T 472 G>E No 1000Genomes
tmp_3_9565683_T_C,G 485 I>L No 1000Genomes
tmp_3_9565683_T_C,G 485 I>V No 1000Genomes
ENSVATH00351539 495 K>N No 1000Genomes
tmp_3_9565637_C_A 500 R>L No 1000Genomes

No associated diseases with Q9LTM7

1 regional properties for Q9LTM7

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 437 - 446 IPR017972

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

53 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O18963 CYP2E1 Cytochrome P450 2E1 Bos taurus (Bovine) PR
Q0IIF9 CYP2U1 Cytochrome P450 2U1 Bos taurus (Bovine) PR
P12394 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Gallus gallus (Chicken) PR
Q8HYN1 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Pan troglodytes (Chimpanzee) PR
Q95078 Cyp18a1 Cytochrome P450 18a1 Drosophila melanogaster (Fruit fly) PR
P10632 CYP2C8 Cytochrome P450 2C8 Homo sapiens (Human) PR
P33260 CYP2C18 Cytochrome P450 2C18 Homo sapiens (Human) PR
Q7Z449 CYP2U1 Cytochrome P450 2U1 Homo sapiens (Human) PR
P05093 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Homo sapiens (Human) PR
P05177 CYP1A2 Cytochrome P450 1A2 Homo sapiens (Human) PR
P05181 CYP2E1 Cytochrome P450 2E1 Homo sapiens (Human) PR
P51589 CYP2J2 Cytochrome P450 2J2 Homo sapiens (Human) PR
Q9CX98 Cyp2u1 Cytochrome P450 2U1 Mus musculus (Mouse) PR
O54749 Cyp2j5 Cytochrome P450 2J5 Mus musculus (Mouse) PR
O54750 Cyp2j6 Cytochrome P450 2J6 Mus musculus (Mouse) PR
P24456 Cyp2d10 Cytochrome P450 2D10 Mus musculus (Mouse) PR
P24457 Cyp2d11 Cytochrome P450 2D11 Mus musculus (Mouse) PR
P27786 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Mus musculus (Mouse) PR
Q9D816 Cyp2c55 Cytochrome P450 2C55 Mus musculus (Mouse) PR
P79383 CYP2E1 Cytochrome P450 2E1 Sus scrofa (Pig) PR
P10633 Cyp2d1 Cytochrome P450 2D1 Rattus norvegicus (Rat) PR
P11715 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Rattus norvegicus (Rat) PR
P12939 Cyp2d10 Cytochrome P450 2D10 Rattus norvegicus (Rat) PR
P20814 Cyp2c13 Cytochrome P450 2C13, male-specific Rattus norvegicus (Rat) PR
O35293 Cyp2f2 Cytochrome P450 2F2 Rattus norvegicus (Rat) PR
P05182 Cyp2e1 Cytochrome P450 2E1 Rattus norvegicus (Rat) PR
P12938 Cyp2d3 Cytochrome P450 2D3 Rattus norvegicus (Rat) PR
P24470 Cyp2c23 Cytochrome P450 2C23 Rattus norvegicus (Rat) PR
P33273 Cyp2c55 Cytochrome P450 2C55 Rattus norvegicus (Rat) PR
P05179 Cyp2c7 Cytochrome P450 2C7 Rattus norvegicus (Rat) PR
Q8HYM9 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Macaca mulatta (Rhesus macaque) PR
A3A871 CYP71Z6 Ent-isokaurene C2/C3-hydroxylase Oryza sativa subsp japonica (Rice) PR
Q6YV88 CYP71Z7 Ent-cassadiene hydroxylase Oryza sativa subsp japonica (Rice) PR
Q7X7X4 CYP99A2 Cytochrome P450 99A2 Oryza sativa subsp japonica (Rice) PR
O48957 CYP99A1 Cytochrome P450 CYP99A1 Sorghum bicolor (Sorghum) (Sorghum vulgare) PR
Q42797 CYP73A11 Trans-cinnamate 4-monooxygenase Glycine max (Soybean) (Glycine hispida) PR
Q9XHC6 CYP93E1 Beta-amyrin 24-hydroxylase Glycine max (Soybean) (Glycine hispida) PR
O81971 CYP71D9 Cytochrome P450 71D9 Glycine max (Soybean) (Glycine hispida) PR
O48922 CYP98A2 Cytochrome P450 98A2 Glycine max (Soybean) (Glycine hispida) PR
Q949U1 CYP79F1 Dihomomethionine N-hydroxylase Arabidopsis thaliana (Mouse-ear cress) PR
Q9CA61 CYP98A8 Cytochrome P450 98A8 Arabidopsis thaliana (Mouse-ear cress) PR
O64636 CYP76C1 Cytochrome P450 76C1 Arabidopsis thaliana (Mouse-ear cress) PR
O64638 CYP76C3 Cytochrome P450 76C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SRQ1 CYP89A9 Cytochrome P450 89A9 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LVD2 CYP71B10 Cytochrome P450 71B10 Arabidopsis thaliana (Mouse-ear cress) PR
O49340 CYP71A12 Cytochrome P450 71A12 Arabidopsis thaliana (Mouse-ear cress) PR
P58049 CYP71B11 Cytochrome P450 71B11 Arabidopsis thaliana (Mouse-ear cress) PR
P58050 CYP71B13 Cytochrome P450 71B13 Arabidopsis thaliana (Mouse-ear cress) PR
Q96514 CYP71B7 Cytochrome P450 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM0 CYP71B23 Cytochrome P450 71B23 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM6 CYP71B17 Cytochrome P450 71B17 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SAE4 CYP71B29 Cytochrome P450 71B29 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZU07 CYP71B12 Cytochrome P450 71B12 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAISLLCLFL ITLVSLIFVV KKIKHSKWDL PPSPPTFPVI GNLHQVGELP HRSFQRLAER
70 80 90 100 110 120
TGHVMLLHFG FVPVTVISSR EAAEEVLRTH DLKCCTRPKL VGSRLISRGF KDISFTPYGE
130 140 150 160 170 180
EWRERRKFLV RELFCFKKVQ YFGYIVEEEC NLLVKKLTES AVGRPPVDLS KSLFWLAASI
190 200 210 220 230 240
LFRIAFGQSF HDNKFIDEDK IDELIFETET AQASFTCSDF FPIAGLGWLA DWISGKHRWL
250 260 270 280 290 300
NNVFFKLDAL FQRVIDDHSD PGRWKDHKDI VDVMLDVMHK QGKDDSLRLT IDHIKGFLTN
310 320 330 340 350 360
IIIAGIDTGA LTMIWAMTEL ARNPELMKNV QGEIRDSFGN NKERITKEDL NKVPFLNMVI
370 380 390 400 410 420
KETFRLHPVA PLLLPRETMT HIKVQGYDIP PKRRILVNTW AIGRDPTLWI NPEEFNPERF
430 440 450 460 470 480
INNPVDYRGQ HFELLPFGSG RRICPGMGLG ITIVELGLLN LLYFFDWRAP DGMTHKDIDT
490 500
EEAGILTVVK KVPLKLVPVR VQ