Q9LTM6

PR
Gene name
CYP71B17 (At3g26160, MTC11.6)
Protein name
Cytochrome P450 71B17
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G26160
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

305-376 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LTM6

Entry ID Method Resolution Chain Position Source
AF-Q9LTM6-F1 Predicted AlphaFoldDB

136 variants for Q9LTM6

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_9569822_G_T 17 T>N No 1000Genomes
ENSVATH02207694 21 C>S No 1000Genomes
ENSVATH02207693 21 C>Y No 1000Genomes
tmp_3_9569807_T_C 22 K>R No 1000Genomes
ENSVATH11002414 25 R>G No 1000Genomes
ENSVATH00351560 27 I>K No 1000Genomes
ENSVATH11002413 31 P>S No 1000Genomes
ENSVATH07979131 33 S>N No 1000Genomes
ENSVATH05920685 35 P>A No 1000Genomes
tmp_3_9569759_G_T 38 P>Q No 1000Genomes
ENSVATH05920684 39 V>I No 1000Genomes
tmp_3_9569754_T_C 40 I>V No 1000Genomes
ENSVATH11002408 48 E>D No 1000Genomes
tmp_3_9569724_G_A 50 P>S No 1000Genomes
ENSVATH11002407 52 R>K No 1000Genomes
tmp_3_9569687_C_G 62 G>A No 1000Genomes
tmp_3_9569688_C_T 62 G>R No 1000Genomes
ENSVATH02207692 68 H>Y No 1000Genomes
tmp_3_9569665_T_A 69 L>F No 1000Genomes
tmp_3_9569658_C_A 72 V>F No 1000Genomes
tmp_3_9569654_G_T 73 P>H No 1000Genomes
tmp_3_9569636_G_A 79 S>L No 1000Genomes
tmp_3_9569591_C_A 94 C>F No 1000Genomes
ENSVATH02207690 94 C>S No 1000Genomes
tmp_3_9569564_G_A 103 S>F No 1000Genomes
tmp_3_9569561_C_A 104 R>M No 1000Genomes
ENSVATH14015428 110 F>L No 1000Genomes
ENSVATH11002405 115 F>S No 1000Genomes
ENSVATH05920682 118 Y>F No 1000Genomes
tmp_3_9569516_C_T 119 G>D No 1000Genomes
ENSVATH05920681 121 E>V No 1000Genomes
ENSVATH05920680 124 E>D No 1000Genomes
tmp_3_9569502_C_T 124 E>K No 1000Genomes
ENSVATH02207687 139 L>V No 1000Genomes
tmp_3_9569453_T_A 140 Q>L No 1000Genomes
tmp_3_9569446_A_T 142 F>L No 1000Genomes
ENSVATH02207686 148 V>E No 1000Genomes
ENSVATH05920678 164 Q>* No 1000Genomes
ENSVATH05920677 164 Q>R No 1000Genomes
tmp_3_9569375_G_A 166 P>L No 1000Genomes
ENSVATH11002364 167 V>F No 1000Genomes
tmp_3_9569368_A_T 168 D>E No 1000Genomes
tmp_3_9569363_C_G 170 S>T No 1000Genomes
ENSVATH11002363 175 W>R No 1000Genomes
ENSVATH11002362 182 F>L No 1000Genomes
tmp_3_9569316_A_G 186 F>L No 1000Genomes
ENSVATH02207683 193 S>I No 1000Genomes
tmp_3_9569287_A_C 195 F>L No 1000Genomes
ENSVATH02207682 196 T>I No 1000Genomes
tmp_3_9569279_G_A 198 T>I No 1000Genomes
tmp_3_9569276_T_C 199 D>G No 1000Genomes
tmp_3_9569268_C_T 202 D>N No 1000Genomes
ENSVATH11002361 208 T>I No 1000Genomes
ENSVATH11002360 211 A>T No 1000Genomes
ENSVATH00351557 213 G>A No 1000Genomes
ENSVATH00351557 213 G>V No 1000Genomes
ENSVATH05920675 214 S>G No 1000Genomes
ENSVATH02207681 224 A>V No 1000Genomes
ENSVATH14015427 225 G>R No 1000Genomes
ENSVATH11002359 227 G>* No 1000Genomes
ENSVATH05920674 230 V>I No 1000Genomes
ENSVATH11002358 235 G>R No 1000Genomes
tmp_3_9569164_T_G 236 Q>H No 1000Genomes
tmp_3_9569141_A_G 244 F>S No 1000Genomes
tmp_3_9569119_T_A 251 L>F No 1000Genomes
tmp_3_9569114_T_C 253 H>R No 1000Genomes
tmp_3_9569112_C_T 254 V>M No 1000Genomes
tmp_3_9569090_G_A 261 P>L No 1000Genomes
ENSVATH05920673 263 R>I No 1000Genomes
ENSVATH09476976 273 V>M No 1000Genomes
ENSVATH02207678 282 G>D No 1000Genomes
tmp_3_9569023_T_G 283 K>N No 1000Genomes
ENSVATH05920672 291 I>T No 1000Genomes
ENSVATH11002355 294 I>T No 1000Genomes
ENSVATH11002334 295 K>N No 1000Genomes
ENSVATH05920671 297 L>F No 1000Genomes
ENSVATH02207677 297 L>H No 1000Genomes
tmp_3_9568980_G_T 298 L>I No 1000Genomes
tmp_3_9568979_A_C 298 L>R No 1000Genomes
ENSVATH11002333 299 T>K No 1000Genomes
tmp_3_9568885_T_A 302 I>L No 1000Genomes
tmp_3_9568882_T_G 303 I>L No 1000Genomes
tmp_3_9568881_A_G 303 I>T No 1000Genomes
tmp_3_9568878_G_C 304 A>G No 1000Genomes
ENSVATH11002326 304 A>S No 1000Genomes
tmp_3_9568868_G_C 307 D>E No 1000Genomes
ENSVATH11002325 308 T>A No 1000Genomes
ENSVATH02207669 309 G>* No 1000Genomes
ENSVATH02207669 309 G>R No 1000Genomes
ENSVATH02207668 326 I>L No 1000Genomes
tmp_3_9568788_A_G 334 I>T No 1000Genomes
tmp_3_9568783_C_T 336 D>N No 1000Genomes
ENSVATH05920666 337 R>L No 1000Genomes
ENSVATH11002302 342 R>M No 1000Genomes
tmp_3_9568750_T_G 347 K>Q No 1000Genomes
tmp_3_9568746_T_A 348 E>V No 1000Genomes
ENSVATH14015363 349 D>N No 1000Genomes
tmp_3_9568733_T_G 352 K>N No 1000Genomes
tmp_3_9568719_T_G 357 N>T No 1000Genomes
tmp_3_9568717_A_T 358 L>M No 1000Genomes
tmp_3_9568714_C_T 359 V>M No 1000Genomes
tmp_3_9568678_G_A 371 P>S No 1000Genomes
tmp_3_9568670_C_A 373 L>F No 1000Genomes
ENSVATH05920665 376 R>W No 1000Genomes
tmp_3_9568651_C_T 380 A>T No 1000Genomes
tmp_3_9568645_C_T,CGA 382 V>I No 1000Genomes
ENSVATH14015362 383 K>* No 1000Genomes
tmp_3_9568611_C_G 393 R>T No 1000Genomes
ENSVATH05920662 397 V>I No 1000Genomes
tmp_3_9568589_C_T 400 W>* No 1000Genomes
ENSVATH11002299 401 A>G No 1000Genomes
ENSVATH14015361 408 L>V No 1000Genomes
ENSVATH11002298 410 T>I No 1000Genomes
tmp_3_9568549_C_G 414 E>Q No 1000Genomes
ENSVATH14015360 416 K>E No 1000Genomes
ENSVATH05920661 417 P>H No 1000Genomes
ENSVATH05920661 417 P>L No 1000Genomes
tmp_3_9568533_C_A 419 R>M No 1000Genomes
ENSVATH11002297 424 P>H No 1000Genomes
ENSVATH11002295 439 S>F No 1000Genomes
ENSVATH02207665 440 G>R No 1000Genomes
ENSVATH05920660 445 P>S No 1000Genomes
ENSVATH11002284 448 A>G No 1000Genomes
ENSVATH11002283 449 M>L No 1000Genomes
tmp_3_9568435_C_T 452 A>T No 1000Genomes
tmp_3_9568404_A_G 462 L>P No 1000Genomes
tmp_3_9568387_T_C 468 K>E No 1000Genomes
ENSVATH11002282 474 S>T No 1000Genomes
tmp_3_9568359_T_G 477 D>A No 1000Genomes
tmp_3_9568353_T_C 479 D>G No 1000Genomes
ENSVATH05920657 484 G>S No 1000Genomes
tmp_3_9568336_T_G 485 T>P No 1000Genomes
tmp_3_9568327_C_T 488 V>I No 1000Genomes
ENSVATH02207664 493 H>P No 1000Genomes
ENSVATH00351554 502 P>L No 1000Genomes
ENSVATH00351554 502 P>Q No 1000Genomes

No associated diseases with Q9LTM6

1 regional properties for Q9LTM6

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 437 - 446 IPR017972

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

53 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O18963 CYP2E1 Cytochrome P450 2E1 Bos taurus (Bovine) PR
Q0IIF9 CYP2U1 Cytochrome P450 2U1 Bos taurus (Bovine) PR
P12394 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Gallus gallus (Chicken) PR
Q8HYN1 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Pan troglodytes (Chimpanzee) PR
Q95078 Cyp18a1 Cytochrome P450 18a1 Drosophila melanogaster (Fruit fly) PR
P10632 CYP2C8 Cytochrome P450 2C8 Homo sapiens (Human) PR
P33260 CYP2C18 Cytochrome P450 2C18 Homo sapiens (Human) PR
Q7Z449 CYP2U1 Cytochrome P450 2U1 Homo sapiens (Human) PR
P05093 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Homo sapiens (Human) PR
P05177 CYP1A2 Cytochrome P450 1A2 Homo sapiens (Human) PR
P05181 CYP2E1 Cytochrome P450 2E1 Homo sapiens (Human) PR
P51589 CYP2J2 Cytochrome P450 2J2 Homo sapiens (Human) PR
Q9CX98 Cyp2u1 Cytochrome P450 2U1 Mus musculus (Mouse) PR
O54749 Cyp2j5 Cytochrome P450 2J5 Mus musculus (Mouse) PR
O54750 Cyp2j6 Cytochrome P450 2J6 Mus musculus (Mouse) PR
P24456 Cyp2d10 Cytochrome P450 2D10 Mus musculus (Mouse) PR
P24457 Cyp2d11 Cytochrome P450 2D11 Mus musculus (Mouse) PR
P27786 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Mus musculus (Mouse) PR
Q9D816 Cyp2c55 Cytochrome P450 2C55 Mus musculus (Mouse) PR
P79383 CYP2E1 Cytochrome P450 2E1 Sus scrofa (Pig) PR
P10633 Cyp2d1 Cytochrome P450 2D1 Rattus norvegicus (Rat) PR
P11715 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Rattus norvegicus (Rat) PR
P12939 Cyp2d10 Cytochrome P450 2D10 Rattus norvegicus (Rat) PR
P20814 Cyp2c13 Cytochrome P450 2C13, male-specific Rattus norvegicus (Rat) PR
O35293 Cyp2f2 Cytochrome P450 2F2 Rattus norvegicus (Rat) PR
P05182 Cyp2e1 Cytochrome P450 2E1 Rattus norvegicus (Rat) PR
P12938 Cyp2d3 Cytochrome P450 2D3 Rattus norvegicus (Rat) PR
P24470 Cyp2c23 Cytochrome P450 2C23 Rattus norvegicus (Rat) PR
P33273 Cyp2c55 Cytochrome P450 2C55 Rattus norvegicus (Rat) PR
P05179 Cyp2c7 Cytochrome P450 2C7 Rattus norvegicus (Rat) PR
Q8HYM9 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Macaca mulatta (Rhesus macaque) PR
A3A871 CYP71Z6 Ent-isokaurene C2/C3-hydroxylase Oryza sativa subsp japonica (Rice) PR
Q6YV88 CYP71Z7 Ent-cassadiene hydroxylase Oryza sativa subsp japonica (Rice) PR
Q7X7X4 CYP99A2 Cytochrome P450 99A2 Oryza sativa subsp japonica (Rice) PR
O48957 CYP99A1 Cytochrome P450 CYP99A1 Sorghum bicolor (Sorghum) (Sorghum vulgare) PR
Q42797 CYP73A11 Trans-cinnamate 4-monooxygenase Glycine max (Soybean) (Glycine hispida) PR
Q9XHC6 CYP93E1 Beta-amyrin 24-hydroxylase Glycine max (Soybean) (Glycine hispida) PR
O81971 CYP71D9 Cytochrome P450 71D9 Glycine max (Soybean) (Glycine hispida) PR
O48922 CYP98A2 Cytochrome P450 98A2 Glycine max (Soybean) (Glycine hispida) PR
Q949U1 CYP79F1 Dihomomethionine N-hydroxylase Arabidopsis thaliana (Mouse-ear cress) PR
Q9CA61 CYP98A8 Cytochrome P450 98A8 Arabidopsis thaliana (Mouse-ear cress) PR
O64636 CYP76C1 Cytochrome P450 76C1 Arabidopsis thaliana (Mouse-ear cress) PR
O64638 CYP76C3 Cytochrome P450 76C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SRQ1 CYP89A9 Cytochrome P450 89A9 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LVD2 CYP71B10 Cytochrome P450 71B10 Arabidopsis thaliana (Mouse-ear cress) PR
O49340 CYP71A12 Cytochrome P450 71A12 Arabidopsis thaliana (Mouse-ear cress) PR
P58049 CYP71B11 Cytochrome P450 71B11 Arabidopsis thaliana (Mouse-ear cress) PR
P58050 CYP71B13 Cytochrome P450 71B13 Arabidopsis thaliana (Mouse-ear cress) PR
Q96514 CYP71B7 Cytochrome P450 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM0 CYP71B23 Cytochrome P450 71B23 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM7 CYP71B16 Cytochrome P450 71B16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SAE4 CYP71B29 Cytochrome P450 71B29 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZU07 CYP71B12 Cytochrome P450 71B12 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAISLLCLFL ITFVSLTIVG CKIKRSIWNL PPSPPKLPVI GNLHQVGELP HRSFRRLAER
70 80 90 100 110 120
TGHVMLLHLG FVPVTVISSR EAAEEVLRTH DLDCCSRPNL VGSRLISRGF KDLNFTPYGE
130 140 150 160 170 180
EWKERRRFLV GELFCSKKLQ SFIYIKEVEC NFLVKKLSES AVDQSPVDLS KTLFWLAASI
190 200 210 220 230 240
LFRVAFGQSF HESEFTDTDK IDELVFETET AQGSFTCSDF FPIAGLGWLV DWISGQHKRL
250 260 270 280 290 300
NDVFLKLDAL LQHVIDDHSN PGRSKDHKDI VDVMLDVMHK QGKDDSLRLT IDHIKGLLTN
310 320 330 340 350 360
IIIAGIDTGA LTMIWTMTEL ARNPEIMKKV QGEIRDRLGN NRERITKEDL DKVPFLNLVI
370 380 390 400 410 420
KETFRLHPVA PLLLPRETMA HVKVQGYDIP PKRRILVNAW AIGRDPKLWT DPEEFKPERF
430 440 450 460 470 480
IDSPVDYRGQ HFELLPFGSG RRICPGMAMG MATLELGLLN LLYFFDWKLP DGMSHKDIDT
490 500
EEAGTLTVVK KVHLKLVPVR VP