P58049

PR
Gene name
CYP71B11 (At5g25120, T11H3.130)
Protein name
Cytochrome P450 71B11
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G25120
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P58049

Entry ID Method Resolution Chain Position Source
AF-P58049-F1 Predicted AlphaFoldDB

95 variants for P58049

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH07037731 8 V>I No 1000Genomes
ENSVATH07037732 15 T>S No 1000Genomes
ENSVATH07037733 16 I>M No 1000Genomes
ENSVATH03117931 22 T>I No 1000Genomes
ENSVATH03117932 24 K>T No 1000Genomes
tmp_5_8662923_A_G 25 T>A No 1000Genomes
ENSVATH03117933 25 T>R No 1000Genomes
tmp_5_8662926_A_C 26 K>Q No 1000Genomes
ENSVATH03117935 35 R>K No 1000Genomes
ENSVATH14182270 40 G>E No 1000Genomes
tmp_5_8662976_G_C,T 42 L>F No 1000Genomes
tmp_5_8662981_A_G 44 Q>R No 1000Genomes
ENSVATH03117938 45 L>M No 1000Genomes
tmp_5_8663003_T_A
ENSVATH00646485
 51 S>R No 1000Genomes
tmp_5_8663005_C_T 52 S>L No 1000Genomes
ENSVATH11022943 58 E>K No 1000Genomes
ENSVATH03117943 59 K>T No 1000Genomes
tmp_5_8663042_G_A 64 M>I No 1000Genomes
ENSVATH03117944 65 A>S No 1000Genomes
ENSVATH03117946 67 R>K No 1000Genomes
tmp_5_8663059_G_T 70 S>I No 1000Genomes
tmp_5_8663083_C_T 78 T>I No 1000Genomes
ENSVATH11022996 81 T>K No 1000Genomes
tmp_5_8663103_G_A 85 V>I No 1000Genomes
ENSVATH07037737 87 K>I No 1000Genomes
tmp_5_8663113_C_A 88 T>K No 1000Genomes
ENSVATH03117952 91 A>V No 1000Genomes
ENSVATH11022997 99 M>T No 1000Genomes
ENSVATH11022998 106 T>A No 1000Genomes
tmp_5_8663221_T_C 124 V>A No 1000Genomes
ENSVATH07037739 128 T>A No 1000Genomes
ENSVATH07037740 134 T>A No 1000Genomes
ENSVATH07037740 134 T>S No 1000Genomes
ENSVATH11022999 138 V>I No 1000Genomes
tmp_5_8663296_T_C 149 V>A No 1000Genomes
ENSVATH07037743 154 D>G No 1000Genomes
ENSVATH03117953 157 T>K No 1000Genomes
ENSVATH07037744 166 V>I No 1000Genomes
ENSVATH07037745 170 T>K No 1000Genomes
ENSVATH14182272 187 I>V No 1000Genomes
ENSVATH07037747 198 Y>C No 1000Genomes
ENSVATH11023000 200 E>D No 1000Genomes
tmp_5_8663493_G_C 215 A>P No 1000Genomes
ENSVATH11023001 216 D>N No 1000Genomes
ENSVATH07037749 220 I>V No 1000Genomes
ENSVATH07037751 223 R>K No 1000Genomes
ENSVATH14182274 237 K>N No 1000Genomes
ENSVATH14182385 247 D>Y No 1000Genomes
tmp_5_8663611_T_A 254 L>Q No 1000Genomes
tmp_5_8663660_G_A 270 M>I No 1000Genomes
tmp_5_8663677_A_G 276 E>G No 1000Genomes
tmp_5_8663698_C_T 283 T>I No 1000Genomes
tmp_5_8663710_C_T 287 T>I No 1000Genomes
tmp_5_8663822_T_G 294 I>S No 1000Genomes
tmp_5_8663836_A_T 299 I>L No 1000Genomes
ENSVATH03117960 301 T>S No 1000Genomes
ENSVATH09584982 305 V>D No 1000Genomes
ENSVATH09584981 305 V>F No 1000Genomes
ENSVATH09584983 307 T>I No 1000Genomes
tmp_5_8663871_G_A 310 M>I No 1000Genomes
ENSVATH03117961 315 S>A No 1000Genomes
ENSVATH03117962 320 M>L No 1000Genomes
tmp_5_8663935_A_G 332 K>E No 1000Genomes
ENSVATH03117965 332 K>R No 1000Genomes
tmp_5_8663938_A_C 333 N>H No 1000Genomes
ENSVATH07037758 342 I>T No 1000Genomes
ENSVATH14182388 344 R>Q No 1000Genomes
ENSVATH11023003 345 L>V No 1000Genomes
ENSVATH07037760 346 E>Q No 1000Genomes
tmp_5_8663982_T_A 347 Y>* No 1000Genomes
ENSVATH03117968 352 V>I No 1000Genomes
ENSVATH11023004 353 K>N No 1000Genomes
tmp_5_8664013_G_GT,A 358 V>I No 1000Genomes
tmp_5_8664016_T_G 359 L>V No 1000Genomes
ENSVATH11023015 361 L>F No 1000Genomes
ENSVATH07037761 364 L>H No 1000Genomes
ENSVATH03117970 373 D>N No 1000Genomes
ENSVATH03117971 374 V>L No 1000Genomes
ENSVATH07037762 379 Y>C No 1000Genomes
tmp_5_8664142_T_G 401 W>G No 1000Genomes
tmp_5_8664185_A_G 415 N>S No 1000Genomes
ENSVATH14182394 426 F>L No 1000Genomes
tmp_5_8664236_G_A 432 G>E No 1000Genomes
ENSVATH07037767 438 G>C No 1000Genomes
tmp_5_8664265_G_A 442 G>S No 1000Genomes
tmp_5_8664278_T_C 446 V>A No 1000Genomes
tmp_5_8664295_A_C 452 N>H No 1000Genomes
ENSVATH07037769 457 F>Y No 1000Genomes
tmp_5_8664317_G_A 459 W>* No 1000Genomes
tmp_5_8664328_G_A 463 E>K No 1000Genomes
ENSVATH07037771 466 E>K No 1000Genomes
tmp_5_8664391_G_A 484 V>I No 1000Genomes
ENSVATH03117976 485 P>S No 1000Genomes
tmp_5_8664410_C_T 490 P>L No 1000Genomes
tmp_5_8664421_C_A 494 Q>K No 1000Genomes

No associated diseases with P58049

1 regional properties for P58049

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 429 - 438 IPR017972

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

53 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O18963 CYP2E1 Cytochrome P450 2E1 Bos taurus (Bovine) PR
Q0IIF9 CYP2U1 Cytochrome P450 2U1 Bos taurus (Bovine) PR
P12394 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Gallus gallus (Chicken) PR
Q8HYN1 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Pan troglodytes (Chimpanzee) PR
Q95078 Cyp18a1 Cytochrome P450 18a1 Drosophila melanogaster (Fruit fly) PR
P10632 CYP2C8 Cytochrome P450 2C8 Homo sapiens (Human) PR
P33260 CYP2C18 Cytochrome P450 2C18 Homo sapiens (Human) PR
Q7Z449 CYP2U1 Cytochrome P450 2U1 Homo sapiens (Human) PR
P05093 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Homo sapiens (Human) PR
P05177 CYP1A2 Cytochrome P450 1A2 Homo sapiens (Human) PR
P05181 CYP2E1 Cytochrome P450 2E1 Homo sapiens (Human) PR
P51589 CYP2J2 Cytochrome P450 2J2 Homo sapiens (Human) PR
Q9CX98 Cyp2u1 Cytochrome P450 2U1 Mus musculus (Mouse) PR
O54749 Cyp2j5 Cytochrome P450 2J5 Mus musculus (Mouse) PR
O54750 Cyp2j6 Cytochrome P450 2J6 Mus musculus (Mouse) PR
P24456 Cyp2d10 Cytochrome P450 2D10 Mus musculus (Mouse) PR
P24457 Cyp2d11 Cytochrome P450 2D11 Mus musculus (Mouse) PR
P27786 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Mus musculus (Mouse) PR
Q9D816 Cyp2c55 Cytochrome P450 2C55 Mus musculus (Mouse) PR
P79383 CYP2E1 Cytochrome P450 2E1 Sus scrofa (Pig) PR
P10633 Cyp2d1 Cytochrome P450 2D1 Rattus norvegicus (Rat) PR
P11715 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Rattus norvegicus (Rat) PR
P12939 Cyp2d10 Cytochrome P450 2D10 Rattus norvegicus (Rat) PR
P20814 Cyp2c13 Cytochrome P450 2C13, male-specific Rattus norvegicus (Rat) PR
O35293 Cyp2f2 Cytochrome P450 2F2 Rattus norvegicus (Rat) PR
P05182 Cyp2e1 Cytochrome P450 2E1 Rattus norvegicus (Rat) PR
P12938 Cyp2d3 Cytochrome P450 2D3 Rattus norvegicus (Rat) PR
P24470 Cyp2c23 Cytochrome P450 2C23 Rattus norvegicus (Rat) PR
P33273 Cyp2c55 Cytochrome P450 2C55 Rattus norvegicus (Rat) PR
P05179 Cyp2c7 Cytochrome P450 2C7 Rattus norvegicus (Rat) PR
Q8HYM9 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Macaca mulatta (Rhesus macaque) PR
Q6YV88 CYP71Z7 Ent-cassadiene hydroxylase Oryza sativa subsp japonica (Rice) PR
A3A871 CYP71Z6 Ent-isokaurene C2/C3-hydroxylase Oryza sativa subsp japonica (Rice) PR
Q7X7X4 CYP99A2 Cytochrome P450 99A2 Oryza sativa subsp japonica (Rice) PR
O48957 CYP99A1 Cytochrome P450 CYP99A1 Sorghum bicolor (Sorghum) (Sorghum vulgare) PR
Q42797 CYP73A11 Trans-cinnamate 4-monooxygenase Glycine max (Soybean) (Glycine hispida) PR
Q9XHC6 CYP93E1 Beta-amyrin 24-hydroxylase Glycine max (Soybean) (Glycine hispida) PR
O81971 CYP71D9 Cytochrome P450 71D9 Glycine max (Soybean) (Glycine hispida) PR
O48922 CYP98A2 Cytochrome P450 98A2 Glycine max (Soybean) (Glycine hispida) PR
Q949U1 CYP79F1 Dihomomethionine N-hydroxylase Arabidopsis thaliana (Mouse-ear cress) PR
Q9CA61 CYP98A8 Cytochrome P450 98A8 Arabidopsis thaliana (Mouse-ear cress) PR
O64636 CYP76C1 Cytochrome P450 76C1 Arabidopsis thaliana (Mouse-ear cress) PR
O64638 CYP76C3 Cytochrome P450 76C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SRQ1 CYP89A9 Cytochrome P450 89A9 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LVD2 CYP71B10 Cytochrome P450 71B10 Arabidopsis thaliana (Mouse-ear cress) PR
O49340 CYP71A12 Cytochrome P450 71A12 Arabidopsis thaliana (Mouse-ear cress) PR
P58050 CYP71B13 Cytochrome P450 71B13 Arabidopsis thaliana (Mouse-ear cress) PR
Q96514 CYP71B7 Cytochrome P450 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM0 CYP71B23 Cytochrome P450 71B23 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM6 CYP71B17 Cytochrome P450 71B17 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM7 CYP71B16 Cytochrome P450 71B16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SAE4 CYP71B29 Cytochrome P450 71B29 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZU07 CYP71B12 Cytochrome P450 71B12 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSLWYIIVAF VFFSTIIIVR NTRKTKKNLP PGPPRLPIIG NLHQLGSKPH SSMFKLSEKY
70 80 90 100 110 120
GPLMALRFGS VSTVVASTPE TVKEVLKTFD AECCSRPYMT YPARLTYNLK DIGFCPYTKY
130 140 150 160 170 180
WREVRKMTVV ELYTAKRVQS FQHTRKEEVA SLVDFITQAA SLEKPVNLNT KLMKLSGSVI
190 200 210 220 230 240
CRVVFGINLK GSKLENLYEE VIQGTMEVVG SFAAADYFPI IGRIIDRITG LHSKCEKIFK
250 260 270 280 290 300
AMDAFFDQSI KHHLEDESIK DDIIDLLLKM ERGEIELGEF QLTRDNTKGI LFNILNAGID
310 320 330 340 350 360
TSAQVMTWVM TYLISNPRVM KKAQAEVREV IKNKDDIIEE DIERLEYLKM VVKETFRVLP
370 380 390 400 410 420
LVPLLIPREA SKDVKIGGYD IPKKTWIHVN IWAIHRNPNV WKDPEAFIPE RFMDNQIDYK
430 440 450 460 470 480
GLNFEFLPFG SGRRMCPGIG MGMALVHLTL INLLYRFDWK LPEGMEVEDV DLEESYGLVC
490
PKKVPLQLIP VLTQWS