Q9LTM0

PR
Gene name
CYP71B23 (At3g26210, MTC11.12)
Protein name
Cytochrome P450 71B23
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G26210
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-68 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LTM0

Entry ID Method Resolution Chain Position Source
AF-Q9LTM0-F1 Predicted AlphaFoldDB

53 variants for Q9LTM0

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_9595192_A_G 4 F>S No 1000Genomes
ENSVATH05921581 15 L>V No 1000Genomes
tmp_3_9595154_T_C 17 T>A No 1000Genomes
ENSVATH05921580 27 S>P No 1000Genomes
ENSVATH05921579 31 L>V No 1000Genomes
ENSVATH02208420 32 P>L No 1000Genomes
ENSVATH05921577 38 L>F No 1000Genomes
ENSVATH14016496 43 N>S No 1000Genomes
ENSVATH00351708 49 G>E No 1000Genomes
ENSVATH00351707 62 H>Y No 1000Genomes
tmp_3_9595016_C_T 63 G>R No 1000Genomes
ENSVATH02208418 72 Y>F No 1000Genomes
ENSVATH00351706 73 V>I No 1000Genomes
ENSVATH14016495 85 E>K No 1000Genomes
ENSVATH02208413 110 N>K No 1000Genomes
tmp_3_9594844_C_T 120 G>D No 1000Genomes
ENSVATH02208411 121 E>K No 1000Genomes
ENSVATH11005204 149 E>A No 1000Genomes
tmp_3_9594736_T_G 156 K>T No 1000Genomes
tmp_3_9594725_C_G 160 E>Q No 1000Genomes
ENSVATH05921569 165 Q>R No 1000Genomes
tmp_3_9594683_G_A 174 L>F No 1000Genomes
tmp_3_9594619_T_C 195 E>G No 1000Genomes
ENSVATH02208408 201 S>I No 1000Genomes
tmp_3_9594589_A_T 205 L>* No 1000Genomes
ENSVATH11005202 211 K>N No 1000Genomes
ENSVATH02208406 220 N>K No 1000Genomes
ENSVATH02208405 240 E>G No 1000Genomes
ENSVATH02208401 247 G>E No 1000Genomes
ENSVATH02208402 247 G>R No 1000Genomes
ENSVATH02208400 259 P>L No 1000Genomes
ENSVATH02208399 264 L>F No 1000Genomes
ENSVATH02208398 276 M>T No 1000Genomes
tmp_3_9594362_T_G 281 S>R No 1000Genomes
tmp_3_9594361_C_G 281 S>T No 1000Genomes
ENSVATH14016452 311 T>A No 1000Genomes
tmp_3_9593867_G_A 323 P>L No 1000Genomes
ENSVATH05921554 329 V>A No 1000Genomes
ENSVATH02208389 342 D>E No 1000Genomes
ENSVATH14016450 350 N>H No 1000Genomes
ENSVATH11005132 382 K>N No 1000Genomes
ENSVATH02208386 390 E>K No 1000Genomes
ENSVATH02208385 415 K>I No 1000Genomes
ENSVATH05921550 419 F>L No 1000Genomes
ENSVATH05921549 420 V>I No 1000Genomes
tmp_3_9593574_C_G 421 D>H No 1000Genomes
tmp_3_9593570_C_A 422 S>I No 1000Genomes
ENSVATH02208378 452 T>K No 1000Genomes
ENSVATH14016449 457 L>F No 1000Genomes
ENSVATH05921546 468 L>S No 1000Genomes
tmp_3_9593429_G_A 469 P>L No 1000Genomes
ENSVATH05921544 473 T>I No 1000Genomes
tmp_3_9593402_T_C 478 D>G No 1000Genomes

No associated diseases with Q9LTM0

1 regional properties for Q9LTM0

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 436 - 445 IPR017972

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

53 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O18963 CYP2E1 Cytochrome P450 2E1 Bos taurus (Bovine) PR
Q0IIF9 CYP2U1 Cytochrome P450 2U1 Bos taurus (Bovine) PR
P12394 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Gallus gallus (Chicken) PR
Q8HYN1 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Pan troglodytes (Chimpanzee) PR
Q95078 Cyp18a1 Cytochrome P450 18a1 Drosophila melanogaster (Fruit fly) PR
P10632 CYP2C8 Cytochrome P450 2C8 Homo sapiens (Human) PR
P33260 CYP2C18 Cytochrome P450 2C18 Homo sapiens (Human) PR
Q7Z449 CYP2U1 Cytochrome P450 2U1 Homo sapiens (Human) PR
P05093 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Homo sapiens (Human) PR
P05177 CYP1A2 Cytochrome P450 1A2 Homo sapiens (Human) PR
P05181 CYP2E1 Cytochrome P450 2E1 Homo sapiens (Human) PR
P51589 CYP2J2 Cytochrome P450 2J2 Homo sapiens (Human) PR
Q9CX98 Cyp2u1 Cytochrome P450 2U1 Mus musculus (Mouse) PR
O54749 Cyp2j5 Cytochrome P450 2J5 Mus musculus (Mouse) PR
O54750 Cyp2j6 Cytochrome P450 2J6 Mus musculus (Mouse) PR
P24456 Cyp2d10 Cytochrome P450 2D10 Mus musculus (Mouse) PR
P24457 Cyp2d11 Cytochrome P450 2D11 Mus musculus (Mouse) PR
P27786 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Mus musculus (Mouse) PR
Q9D816 Cyp2c55 Cytochrome P450 2C55 Mus musculus (Mouse) PR
P79383 CYP2E1 Cytochrome P450 2E1 Sus scrofa (Pig) PR
P10633 Cyp2d1 Cytochrome P450 2D1 Rattus norvegicus (Rat) PR
P11715 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Rattus norvegicus (Rat) PR
P12939 Cyp2d10 Cytochrome P450 2D10 Rattus norvegicus (Rat) PR
P20814 Cyp2c13 Cytochrome P450 2C13, male-specific Rattus norvegicus (Rat) PR
O35293 Cyp2f2 Cytochrome P450 2F2 Rattus norvegicus (Rat) PR
P05182 Cyp2e1 Cytochrome P450 2E1 Rattus norvegicus (Rat) PR
P12938 Cyp2d3 Cytochrome P450 2D3 Rattus norvegicus (Rat) PR
P24470 Cyp2c23 Cytochrome P450 2C23 Rattus norvegicus (Rat) PR
P33273 Cyp2c55 Cytochrome P450 2C55 Rattus norvegicus (Rat) PR
P05179 Cyp2c7 Cytochrome P450 2C7 Rattus norvegicus (Rat) PR
Q8HYM9 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Macaca mulatta (Rhesus macaque) PR
A3A871 CYP71Z6 Ent-isokaurene C2/C3-hydroxylase Oryza sativa subsp japonica (Rice) PR
Q6YV88 CYP71Z7 Ent-cassadiene hydroxylase Oryza sativa subsp japonica (Rice) PR
Q7X7X4 CYP99A2 Cytochrome P450 99A2 Oryza sativa subsp japonica (Rice) PR
O48957 CYP99A1 Cytochrome P450 CYP99A1 Sorghum bicolor (Sorghum) (Sorghum vulgare) PR
Q42797 CYP73A11 Trans-cinnamate 4-monooxygenase Glycine max (Soybean) (Glycine hispida) PR
Q9XHC6 CYP93E1 Beta-amyrin 24-hydroxylase Glycine max (Soybean) (Glycine hispida) PR
O81971 CYP71D9 Cytochrome P450 71D9 Glycine max (Soybean) (Glycine hispida) PR
O48922 CYP98A2 Cytochrome P450 98A2 Glycine max (Soybean) (Glycine hispida) PR
Q949U1 CYP79F1 Dihomomethionine N-hydroxylase Arabidopsis thaliana (Mouse-ear cress) PR
Q9CA61 CYP98A8 Cytochrome P450 98A8 Arabidopsis thaliana (Mouse-ear cress) PR
O64636 CYP76C1 Cytochrome P450 76C1 Arabidopsis thaliana (Mouse-ear cress) PR
O64638 CYP76C3 Cytochrome P450 76C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SRQ1 CYP89A9 Cytochrome P450 89A9 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LVD2 CYP71B10 Cytochrome P450 71B10 Arabidopsis thaliana (Mouse-ear cress) PR
O49340 CYP71A12 Cytochrome P450 71A12 Arabidopsis thaliana (Mouse-ear cress) PR
P58049 CYP71B11 Cytochrome P450 71B11 Arabidopsis thaliana (Mouse-ear cress) PR
P58050 CYP71B13 Cytochrome P450 71B13 Arabidopsis thaliana (Mouse-ear cress) PR
Q96514 CYP71B7 Cytochrome P450 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM6 CYP71B17 Cytochrome P450 71B17 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM7 CYP71B16 Cytochrome P450 71B16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SAE4 CYP71B29 Cytochrome P450 71B29 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZU07 CYP71B12 Cytochrome P450 71B12 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSIFLCFLLL LLLLLVTIIF TRKSQSSKLK LPPGPPKLPI IGNLHYLNGL PHKCLLNLWK
70 80 90 100 110 120
IHGPVMQLQL GYVPLVVISS NQAAEEVLKT HDLDCCSRPE TIASKTISYN FKDIGFAPYG
130 140 150 160 170 180
EEWRALRKLA VIELFSLKKF NSFRYIREEE NDLLVKKLSE ASEKQSPVNL KKALFTLSAS
190 200 210 220 230 240
IVCRLAFGQN LHESEFIDED SMEDLASRSE KIQAKFAFSN FFPGGWILDK ITGQSKSLNE
250 260 270 280 290 300
IFADLDGFFN QVLDDHLKPG RKVLETPDVV DVMIDMMNKQ SQDGSFKLTT DHIKGIISDI
310 320 330 340 350 360
FLAGVNTSAT TILWAMTELI RNPRVMKKVQ DEVRTVLGEK RDRITEQDLN QLNYFKLVIK
370 380 390 400 410 420
ETFRLHPAAP LLLPREAMAK IKIQGYDIPE KTQIMVNVYA IGRDPDLWEN PEEFKPERFV
430 440 450 460 470 480
DSSVDYRGLN FELLPFGSGR RICPGMTMGI ATVELGLLNL LYFFDWGLPE GRTVKDIDLE
490 500
EEGAIIIGKK VSLELVPTRR Q