Q9LVD2

PR
Gene name
CYP71B10 (At5g57260, MJB24.7)
Protein name
Cytochrome P450 71B10
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G57260
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LVD2

Entry ID Method Resolution Chain Position Source
AF-Q9LVD2-F1 Predicted AlphaFoldDB

50 variants for Q9LVD2

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH03443695 10 I>L No 1000Genomes
ENSVATH03443694 11 L>F No 1000Genomes
ENSVATH03443693 14 S>F No 1000Genomes
ENSVATH03443692 15 I>F No 1000Genomes
ENSVATH07439042 20 V>I No 1000Genomes
tmp_5_23200193_C_A 27 W>C No 1000Genomes
tmp_5_23200144_G_A 44 H>Y No 1000Genomes
ENSVATH12824907 64 V>I No 1000Genomes
tmp_5_23200069_G_T 69 L>I No 1000Genomes
tmp_5_23199894_T_C 127 K>R No 1000Genomes
ENSVATH12824906 128 L>V No 1000Genomes
tmp_5_23199824_C_T 150 M>I No 1000Genomes
ENSVATH07439039 157 I>T No 1000Genomes
ENSVATH07439038 168 N>I No 1000Genomes
tmp_5_23199739_T_G 179 N>H No 1000Genomes
tmp_5_23199714_C_A 187 G>V No 1000Genomes
tmp_5_23199708_T_G 189 N>T No 1000Genomes
tmp_5_23199705_A_T 190 F>Y No 1000Genomes
tmp_5_23199672_T_A 201 Q>L No 1000Genomes
ENSVATH07439037 224 G>V No 1000Genomes
tmp_5_23199600_C_T 225 W>* No 1000Genomes
ENSVATH14637310 237 R>K No 1000Genomes
ENSVATH14637309 239 R>G No 1000Genomes
tmp_5_23199537_G_T 246 A>D No 1000Genomes
tmp_5_23199516_T_G 253 D>A No 1000Genomes
ENSVATH07439036 259 N>K No 1000Genomes
ENSVATH07439035 264 E>K No 1000Genomes
tmp_5_23199481_C_T 265 D>N No 1000Genomes
ENSVATH03443689 278 E>D No 1000Genomes
ENSVATH03443690 278 E>Q No 1000Genomes
ENSVATH07439034 280 V>I No 1000Genomes
ENSVATH07439033 284 G>S No 1000Genomes
ENSVATH07439032 286 L>I No 1000Genomes
tmp_5_23199397_C_G 293 A>P No 1000Genomes
ENSVATH07439030 308 I>L No 1000Genomes
ENSVATH14637308 314 M>I No 1000Genomes
ENSVATH03443687 332 R>I No 1000Genomes
tmp_5_23199197_C_G 336 G>R No 1000Genomes
ENSVATH07439029 355 L>P No 1000Genomes
ENSVATH12824905 357 M>I No 1000Genomes
tmp_5_23199086_C_T 373 V>I No 1000Genomes
tmp_5_23199043_G_C 387 T>R No 1000Genomes
ENSVATH07439028 399 W>S No 1000Genomes
ENSVATH14637307 413 E>D No 1000Genomes
tmp_5_23198960_G_A 415 L>F No 1000Genomes
ENSVATH07439026 458 A>T No 1000Genomes
tmp_5_23198806_C_T 466 W>* No 1000Genomes
ENSVATH14637306 469 P>S No 1000Genomes
ENSVATH07439025 490 K>T No 1000Genomes
tmp_5_23198706_T_A 499 K>N No 1000Genomes

No associated diseases with Q9LVD2

1 regional properties for Q9LVD2

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 436 - 445 IPR017972

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

3 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

53 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O18963 CYP2E1 Cytochrome P450 2E1 Bos taurus (Bovine) PR
Q0IIF9 CYP2U1 Cytochrome P450 2U1 Bos taurus (Bovine) PR
P12394 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Gallus gallus (Chicken) PR
Q8HYN1 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Pan troglodytes (Chimpanzee) PR
Q95078 Cyp18a1 Cytochrome P450 18a1 Drosophila melanogaster (Fruit fly) PR
P10632 CYP2C8 Cytochrome P450 2C8 Homo sapiens (Human) PR
P33260 CYP2C18 Cytochrome P450 2C18 Homo sapiens (Human) PR
Q7Z449 CYP2U1 Cytochrome P450 2U1 Homo sapiens (Human) PR
P05093 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Homo sapiens (Human) PR
P05177 CYP1A2 Cytochrome P450 1A2 Homo sapiens (Human) PR
P05181 CYP2E1 Cytochrome P450 2E1 Homo sapiens (Human) PR
P51589 CYP2J2 Cytochrome P450 2J2 Homo sapiens (Human) PR
Q9CX98 Cyp2u1 Cytochrome P450 2U1 Mus musculus (Mouse) PR
O54749 Cyp2j5 Cytochrome P450 2J5 Mus musculus (Mouse) PR
O54750 Cyp2j6 Cytochrome P450 2J6 Mus musculus (Mouse) PR
P24456 Cyp2d10 Cytochrome P450 2D10 Mus musculus (Mouse) PR
P24457 Cyp2d11 Cytochrome P450 2D11 Mus musculus (Mouse) PR
P27786 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Mus musculus (Mouse) PR
Q9D816 Cyp2c55 Cytochrome P450 2C55 Mus musculus (Mouse) PR
P79383 CYP2E1 Cytochrome P450 2E1 Sus scrofa (Pig) PR
P10633 Cyp2d1 Cytochrome P450 2D1 Rattus norvegicus (Rat) PR
P11715 Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase Rattus norvegicus (Rat) PR
P12939 Cyp2d10 Cytochrome P450 2D10 Rattus norvegicus (Rat) PR
P20814 Cyp2c13 Cytochrome P450 2C13, male-specific Rattus norvegicus (Rat) PR
O35293 Cyp2f2 Cytochrome P450 2F2 Rattus norvegicus (Rat) PR
P05182 Cyp2e1 Cytochrome P450 2E1 Rattus norvegicus (Rat) PR
P12938 Cyp2d3 Cytochrome P450 2D3 Rattus norvegicus (Rat) PR
P24470 Cyp2c23 Cytochrome P450 2C23 Rattus norvegicus (Rat) PR
P33273 Cyp2c55 Cytochrome P450 2C55 Rattus norvegicus (Rat) PR
P05179 Cyp2c7 Cytochrome P450 2C7 Rattus norvegicus (Rat) PR
Q8HYM9 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase Macaca mulatta (Rhesus macaque) PR
A3A871 CYP71Z6 Ent-isokaurene C2/C3-hydroxylase Oryza sativa subsp japonica (Rice) PR
Q6YV88 CYP71Z7 Ent-cassadiene hydroxylase Oryza sativa subsp japonica (Rice) PR
Q7X7X4 CYP99A2 Cytochrome P450 99A2 Oryza sativa subsp japonica (Rice) PR
O48957 CYP99A1 Cytochrome P450 CYP99A1 Sorghum bicolor (Sorghum) (Sorghum vulgare) PR
Q42797 CYP73A11 Trans-cinnamate 4-monooxygenase Glycine max (Soybean) (Glycine hispida) PR
Q9XHC6 CYP93E1 Beta-amyrin 24-hydroxylase Glycine max (Soybean) (Glycine hispida) PR
O81971 CYP71D9 Cytochrome P450 71D9 Glycine max (Soybean) (Glycine hispida) PR
O48922 CYP98A2 Cytochrome P450 98A2 Glycine max (Soybean) (Glycine hispida) PR
Q9SAE4 CYP71B29 Cytochrome P450 71B29 Arabidopsis thaliana (Mouse-ear cress) PR
Q96514 CYP71B7 Cytochrome P450 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9CA61 CYP98A8 Cytochrome P450 98A8 Arabidopsis thaliana (Mouse-ear cress) PR
O49340 CYP71A12 Cytochrome P450 71A12 Arabidopsis thaliana (Mouse-ear cress) PR
O64636 CYP76C1 Cytochrome P450 76C1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM7 CYP71B16 Cytochrome P450 71B16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM6 CYP71B17 Cytochrome P450 71B17 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTM0 CYP71B23 Cytochrome P450 71B23 Arabidopsis thaliana (Mouse-ear cress) PR
P58049 CYP71B11 Cytochrome P450 71B11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZU07 CYP71B12 Cytochrome P450 71B12 Arabidopsis thaliana (Mouse-ear cress) PR
P58050 CYP71B13 Cytochrome P450 71B13 Arabidopsis thaliana (Mouse-ear cress) PR
O64638 CYP76C3 Cytochrome P450 76C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SRQ1 CYP89A9 Cytochrome P450 89A9 Arabidopsis thaliana (Mouse-ear cress) PR
Q949U1 CYP79F1 Dihomomethionine N-hydroxylase Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MTVLWFVSLI LLISILLVAV KHSKRRWVRQ PPSPPGLPII GNLHQLGELP HQSLCKLSKK
70 80 90 100 110 120
YGPVMLLKLG RVPTVIVSTP ETAKQVLKDY DLHCCSRPSL EGTRKLSYNY LDIAFSRFDD
130 140 150 160 170 180
YWKELRKLCV EELFCNKRIN SIQPIKEAEM EKLIDSIAES ASQKTLVNLS DTFLSLNVNV
190 200 210 220 230 240
ICKAVFGVNF QGTVLNNDKF QDLVHEALEM LGSFSASDFF PYVGWIVDWF TGLHARRERS
250 260 270 280 290 300
VRDLDAFYEQ MIDLHLQKNR EESEDDFVDL LLRLEKEEAV LGYGKLTRNH IKAILMNILL
310 320 330 340 350 360
GGINTSAITM TWAMAELIRN PRVMKKVQSE IRAQIGKNNK TRIISLDEIN HLSYLNMVIK
370 380 390 400 410 420
ETCRLHPVAP LLVPREVISE FKINGYTIQP KTRLHVNVWA IGRDPEIWKD PEEFLPERFM
430 440 450 460 470 480
DCDIDVKGQD YELLPFGSGR RICPAVYMGI TTVEFGLANL LYHFDWKLPE GVAVEDIYMD
490 500
EASGLTSHKK HDLLLVPVKS LV