Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8UVJ7

Entry ID Method Resolution Chain Position Source
AF-Q8UVJ7-F1 Predicted AlphaFoldDB

No variants for Q8UVJ7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8UVJ7

No associated diseases with Q8UVJ7

No regional properties for Q8UVJ7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8UVJ7

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
calcium ion binding Binding to a calcium ion (Ca2+).

1 GO annotations of biological process

Name Definition
homophilic cell adhesion via plasma membrane adhesion molecules The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.

41 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3SWX5 CDH6 Cadherin-6 Bos taurus (Bovine) PR
P79995 CDH10 Cadherin-10 Gallus gallus (Chicken) PR
Q5DRC8 PCDHB6 Protocadherin beta-6 Pan troglodytes (Chimpanzee) PR
Q5DRE4 PCDHA8 Protocadherin alpha-8 Pan troglodytes (Chimpanzee) PR
Q5DRE6 PCDHA6 Protocadherin alpha-6 Pan troglodytes (Chimpanzee) PR
Q5DRF0 PCDHA2 Protocadherin alpha-2 Pan troglodytes (Chimpanzee) PR
Q5DRE7 PCDHA5 Protocadherin alpha-5 Pan troglodytes (Chimpanzee) PR
Q9VJB6 CadN2 Putative neural-cadherin 2 Drosophila melanogaster (Fruit fly) PR
Q9ULB4 CDH9 Cadherin-9 Homo sapiens (Human) PR
Q9Y5E3 PCDHB6 Protocadherin beta-6 Homo sapiens (Human) PR
Q9Y5F1 PCDHB12 Protocadherin beta-12 Homo sapiens (Human) PR
O60330 PCDHGA12 Protocadherin gamma-A12 Homo sapiens (Human) PR
P12830 CDH1 Cadherin-1 Homo sapiens (Human) PR
Q9H159 CDH19 Cadherin-19 Homo sapiens (Human) PR
Q9P2E7 PCDH10 Protocadherin-10 Homo sapiens (Human) PR
Q9Y6N8 CDH10 Cadherin-10 Homo sapiens (Human) PR
P55285 CDH6 Cadherin-6 Homo sapiens (Human) PR
P19022 CDH2 Cadherin-2 Homo sapiens (Human) PR
Q9Y5I2 PCDHA10 Protocadherin alpha-10 Homo sapiens (Human) PR
Q6ZTQ4 CDHR3 Cadherin-related family member 3 Homo sapiens (Human) PR
Q9Y5H3 PCDHGA10 Protocadherin gamma-A10 Homo sapiens (Human) PR
Q9UN75 PCDHA12 Protocadherin alpha-12 Homo sapiens (Human) PR
Q9Y5I1 PCDHA11 Protocadherin alpha-11 Homo sapiens (Human) PR
Q9Y5H8 PCDHA3 Protocadherin alpha-3 Homo sapiens (Human) PR
Q9Y5H9 PCDHA2 Protocadherin alpha-2 Homo sapiens (Human) PR
Q9UN73 PCDHA6 Protocadherin alpha-6 Homo sapiens (Human) PR
Q9Y5H6 PCDHA8 Protocadherin alpha-8 Homo sapiens (Human) PR
Q9UN74 PCDHA4 Protocadherin alpha-4 Homo sapiens (Human) PR
Q9UN72 PCDHA7 Protocadherin alpha-7 Homo sapiens (Human) PR
Q9Y5H7 PCDHA5 Protocadherin alpha-5 Homo sapiens (Human) PR
Q9Y5G4 PCDHGA9 Protocadherin gamma-A9 Homo sapiens (Human) PR
Q9Y5G0 PCDHGB5 Protocadherin gamma-B5 Homo sapiens (Human) PR
P09803 Cdh1 Cadherin-1 Mus musculus (Mouse) PR
P15116 Cdh2 Cadherin-2 Mus musculus (Mouse) PR
P70407 Cdh9 Cadherin-9 Mus musculus (Mouse) PR
P97326 Cdh6 Cadherin-6 Mus musculus (Mouse) PR
P70408 Cdh10 Cadherin-10 Mus musculus (Mouse) PR
Q8VHF2 Cdhr5 Cadherin-related family member 5 Mus musculus (Mouse) PR
P55280 Cdh6 Cadherin-6 Rattus norvegicus (Rat) PR
Q9Z1Y3 Cdh2 Cadherin-2 Rattus norvegicus (Rat) PR
Q767I8 Pcdha4 Protocadherin alpha-4 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MKHVRHFIPS LFLSLVHVCL VQANYAPYFF DNGARSTNGN MALLSLSEDT PVGSHVYTLN
70 80 90 100 110 120
GTDPEGDPVT YGLTYEAGSR RYFSVDGNLG NVTLIEELDR EKEDEIEVIV SISDGLSTVS
130 140 150 160 170 180
EKVRILVMDA NDESPEFINT PYIVQVPENS PSGSSIFKIE AVDRDTGSGG SITYFLQNIH
190 200 210 220 230 240
ANKFTIDRHS GVLRIKSGVT LDYEKSRTHF VVVVAKDGGG KLRGDNKVFS ATTTVTVNVE
250 260 270 280 290 300
DVQDTPPMFI GTPYYGYVYE DTLPGSEVLT VVALDGDRGK PNNIHYCIVN GSEGSFEISN
310 320 330 340 350 360
TTGAISVIKS PNQLKKEVYE LRVQASEVSP EGDVSAYAFA TVTIRVVDLN NHPPTFYGES
370 380 390 400 410 420
GPQNRFELTM YEHPPEGEIL RGLKITVNDS DQGANAKFNL RLVGPGGIFR VVPLTVLNEA
430 440 450 460 470 480
QVTIIVENSA AIDYEKFKVL TFKLLAIEVN TPEKFSSTAD IAIRLLDTND NVPKFSSDYY
490 500 510 520 530 540
IARIPENSPG GSNVVAVTAT DPDSGLWGEV KYSIYGTGAD LFLIHPSTGI IYTQPWAVLD
550 560 570 580 590 600
AEVNSKYNFY VKAEDTDGKY SLAEVFITVL DVNDHSPEFN ENIQEKTMII GSPVKIEAID
610 620 630 640 650 660
QDAEEPNNIV DYSIMQADPA NVFDIDQSTG EIKLKSYIRS LDIIHNITKN KDCIWSLVVQ
670 680 690 700 710 720
AKDRGSPSFS TTAVLKIDIT EETLHKGPMA AFLMQTKDNP MKALGVLAGV MGIMVLITIM
730 740 750 760 770 780
ISTAMFWRNK RSNKIMPVRR IIKKRQTQQS RTVRMEWLKF KRPSNAAEKF VVEDDAKSLQ
790 800 810 820 830 840
NENSNNNVQA APVPPAAPLP PPPPALAASG NTTAWRVPTV SGSLTPKFIN KQLKKRGHSS
850 860
THNALVSELK MKFEKRNASM GEPHI