P79995
Gene name |
CDH10 |
Protein name |
Cadherin-10 |
Names |
|
Species |
Gallus gallus (Chicken) |
KEGG Pathway |
gga:408049 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P79995
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P79995-F1 | Predicted | AlphaFoldDB |
6 variants for P79995
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs731738406 | 274 | I>L | No | Ensembl | |
| rs737849673 | 275 | H>P | No | Ensembl | |
| rs15116233 | 291 | I>V | No | Ensembl | |
| rs733566406 | 601 | E>G | No | Ensembl | |
| rs731020575 | 676 | R>G | No | Ensembl | |
| rs316690472 | 788 | A>T | No | Ensembl |
No associated diseases with P79995
8 regional properties for P79995
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cadherin, Y-type LIR-motif | 722 - 780 | IPR000233 |
| domain | Cadherin-like | 70 - 160 | IPR002126-1 |
| domain | Cadherin-like | 160 - 280 | IPR002126-2 |
| domain | Cadherin-like | 270 - 384 | IPR002126-3 |
| domain | Cadherin-like | 385 - 489 | IPR002126-4 |
| domain | Cadherin-like | 489 - 603 | IPR002126-5 |
| conserved_site | Cadherin conserved site | 257 - 267 | IPR020894-1 |
| conserved_site | Cadherin conserved site | 477 - 487 | IPR020894-2 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium ion binding | Binding to a calcium ion (Ca2+). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| homophilic cell adhesion via plasma membrane adhesion molecules | The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell. |
41 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q3SWX5 | CDH6 | Cadherin-6 | Bos taurus (Bovine) | PR |
| Q8UVJ7 | CDHR1 | Cadherin-related family member 1 | Gallus gallus (Chicken) | PR |
| Q5DRC8 | PCDHB6 | Protocadherin beta-6 | Pan troglodytes (Chimpanzee) | PR |
| Q5DRE4 | PCDHA8 | Protocadherin alpha-8 | Pan troglodytes (Chimpanzee) | PR |
| Q5DRE6 | PCDHA6 | Protocadherin alpha-6 | Pan troglodytes (Chimpanzee) | PR |
| Q5DRF0 | PCDHA2 | Protocadherin alpha-2 | Pan troglodytes (Chimpanzee) | PR |
| Q5DRE7 | PCDHA5 | Protocadherin alpha-5 | Pan troglodytes (Chimpanzee) | PR |
| Q9VJB6 | CadN2 | Putative neural-cadherin 2 | Drosophila melanogaster (Fruit fly) | PR |
| Q9ULB4 | CDH9 | Cadherin-9 | Homo sapiens (Human) | PR |
| Q9Y5E3 | PCDHB6 | Protocadherin beta-6 | Homo sapiens (Human) | PR |
| Q9Y5F1 | PCDHB12 | Protocadherin beta-12 | Homo sapiens (Human) | PR |
| O60330 | PCDHGA12 | Protocadherin gamma-A12 | Homo sapiens (Human) | PR |
| P12830 | CDH1 | Cadherin-1 | Homo sapiens (Human) | PR |
| Q9H159 | CDH19 | Cadherin-19 | Homo sapiens (Human) | PR |
| Q9P2E7 | PCDH10 | Protocadherin-10 | Homo sapiens (Human) | PR |
| P55285 | CDH6 | Cadherin-6 | Homo sapiens (Human) | PR |
| P19022 | CDH2 | Cadherin-2 | Homo sapiens (Human) | PR |
| Q9Y5I2 | PCDHA10 | Protocadherin alpha-10 | Homo sapiens (Human) | PR |
| Q6ZTQ4 | CDHR3 | Cadherin-related family member 3 | Homo sapiens (Human) | PR |
| Q9Y5H3 | PCDHGA10 | Protocadherin gamma-A10 | Homo sapiens (Human) | PR |
| Q9UN75 | PCDHA12 | Protocadherin alpha-12 | Homo sapiens (Human) | PR |
| Q9Y5I1 | PCDHA11 | Protocadherin alpha-11 | Homo sapiens (Human) | PR |
| Q9Y5H8 | PCDHA3 | Protocadherin alpha-3 | Homo sapiens (Human) | PR |
| Q9Y5H9 | PCDHA2 | Protocadherin alpha-2 | Homo sapiens (Human) | PR |
| Q9UN73 | PCDHA6 | Protocadherin alpha-6 | Homo sapiens (Human) | PR |
| Q9Y5H6 | PCDHA8 | Protocadherin alpha-8 | Homo sapiens (Human) | PR |
| Q9UN74 | PCDHA4 | Protocadherin alpha-4 | Homo sapiens (Human) | PR |
| Q9UN72 | PCDHA7 | Protocadherin alpha-7 | Homo sapiens (Human) | PR |
| Q9Y5H7 | PCDHA5 | Protocadherin alpha-5 | Homo sapiens (Human) | PR |
| Q9Y5G4 | PCDHGA9 | Protocadherin gamma-A9 | Homo sapiens (Human) | PR |
| Q9Y5G0 | PCDHGB5 | Protocadherin gamma-B5 | Homo sapiens (Human) | PR |
| Q9Y6N8 | CDH10 | Cadherin-10 | Homo sapiens (Human) | PR |
| P09803 | Cdh1 | Cadherin-1 | Mus musculus (Mouse) | PR |
| P15116 | Cdh2 | Cadherin-2 | Mus musculus (Mouse) | PR |
| P70407 | Cdh9 | Cadherin-9 | Mus musculus (Mouse) | PR |
| P97326 | Cdh6 | Cadherin-6 | Mus musculus (Mouse) | PR |
| Q8VHF2 | Cdhr5 | Cadherin-related family member 5 | Mus musculus (Mouse) | PR |
| P70408 | Cdh10 | Cadherin-10 | Mus musculus (Mouse) | PR |
| P55280 | Cdh6 | Cadherin-6 | Rattus norvegicus (Rat) | PR |
| Q9Z1Y3 | Cdh2 | Cadherin-2 | Rattus norvegicus (Rat) | PR |
| Q767I8 | Pcdha4 | Protocadherin alpha-4 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTIQQVLLLL | LLWMWLLHPC | RTEMLFRRTP | DLRPKGFVGR | TSGSDGKALH | RQKRGWMWNQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FFLLEEYTGS | DYQYVGKLHS | DQDKGDGSLK | YILSGDGAGT | LFIIDEKTGD | IHATRRIDRE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EKAFYTLRAQ | AINRRTLRPV | EPESEFVIKI | HDINDNEPTF | PEEIYTASVP | EMSVVGTSVV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QVTATDADDP | SYGNSARIIY | SILQGQPYFS | VEPETGIIRT | ALPNMNRENR | EQYQVVIQAK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DMGGQMGGLS | GTTTVNITLT | DVNDNPPRFP | QSTIHLRIPE | SSPVGTPIGS | IKATDADTGK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NAEVEYRIID | GDGTDMFDIV | TQRDTQEGII | TVRKPLDYET | RRLYTLKVEA | ENTHVDPRFY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YLGPFKDTTI | VKISVEDVDE | PPVFSRSSYL | FEVHEDIELG | TIIGTVMARD | PDSASSPIRF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SLDRHTDLDR | IFNIHSGNGS | IYTSKPLDRE | ISQWHNLSVI | AAEINNLKDT | TRVPVYVRIL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DVNDNAPQFA | VFYDTFVCEN | ARAGQLIQTI | SAVDKDDPLG | GQKFFFSLAA | VNPNFTVQDN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EDNTARILTR | RNGFSRHEIS | TYLLPVVISD | NDYPIQSSTG | TLTIRVCACD | SRGNMQSCNA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| EALLLPAGLS | TGALIAILLC | IIILLVIVVL | FAALKRQRKK | EPLILSKEDI | RDNIVSYNDE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| GGGEEDTQAF | DIGTLRNPAA | IEDKKLRRDI | IPETLFVPRR | TPSAPDNTDV | RDFINQRLKE |
| 730 | 740 | 750 | 760 | 770 | 780 |
| HDSDPSAPPY | DSLATYAYEG | NDSIAESLSS | LESGTTEGDQ | NYDYLREWGP | RFNKLAEMYG |
| GGESDKDAS |