Q8L838
PR
Gene name |
COG4 |
Protein name |
Conserved oligomeric Golgi complex subunit 4 |
Names |
COG complex subunit 4, Component of oligomeric Golgi complex 4 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G01395 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8L838
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8L838-F1 | Predicted | AlphaFoldDB |
45 variants for Q8L838
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_575620_G_A | 10 | A>V | No | 1000Genomes | |
| tmp_4_575612_T_G | 13 | T>P | No | 1000Genomes | |
| tmp_4_575604_A_T | 15 | D>E | No | 1000Genomes | |
| ENSVATH08202886 | 19 | V>I | No | 1000Genomes | |
| ENSVATH06413128 | 28 | E>K | No | 1000Genomes | |
| tmp_4_575455_G_C | 65 | T>R | No | 1000Genomes | |
| ENSVATH06413126 | 69 | R>W | No | 1000Genomes | |
| tmp_4_575416_G_C | 78 | A>G | No | 1000Genomes | |
| tmp_4_575412_C_A | 79 | E>D | No | 1000Genomes | |
| tmp_4_575294_C_T | 119 | V>I | No | 1000Genomes | |
| tmp_4_575288_C_G | 121 | V>L | No | 1000Genomes | |
| ENSVATH02610280 | 144 | E>K | No | 1000Genomes | |
| tmp_4_575177_A_T | 158 | F>I | No | 1000Genomes | |
| ENSVATH10493766 | 165 | Y>F | No | 1000Genomes | |
| ENSVATH06413124 | 170 | S>Y | No | 1000Genomes | |
| ENSVATH10493765 | 177 | H>R | No | 1000Genomes | |
| tmp_4_575099_C_G | 184 | E>Q | No | 1000Genomes | |
| ENSVATH06413122 | 203 | I>T | No | 1000Genomes | |
| ENSVATH10493694 | 217 | T>R | No | 1000Genomes | |
| tmp_4_574915_A_T,C | 245 | L>H | No | 1000Genomes | |
| tmp_4_574915_A_T,C | 245 | L>R | No | 1000Genomes | |
| ENSVATH00451889 | 248 | Q>P | No | 1000Genomes | |
| tmp_4_574858_T_C | 264 | K>R | No | 1000Genomes | |
| tmp_4_574745_A_C | 302 | S>A | No | 1000Genomes | |
| tmp_4_574663_A_T | 329 | I>N | No | 1000Genomes | |
| tmp_4_574655_C_T | 332 | G>S | No | 1000Genomes | |
| tmp_4_574617_C_G | 344 | E>D | No | 1000Genomes | |
| ENSVATH06413119 | 346 | Y>F | No | 1000Genomes | |
| ENSVATH00451887 | 394 | A>P | No | 1000Genomes | |
| ENSVATH00451887 | 394 | A>T | No | 1000Genomes | |
| ENSVATH02610276 | 427 | S>R | No | 1000Genomes | |
| ENSVATH06413117 | 428 | L>H | No | 1000Genomes | |
| tmp_4_574353_C_T | 432 | M>I | No | 1000Genomes | |
| tmp_4_574354_A_T | 432 | M>K | No | 1000Genomes | |
| tmp_4_574355_T_C | 432 | M>V | No | 1000Genomes | |
| ENSVATH06413115 | 469 | N>S | No | 1000Genomes | |
| ENSVATH00451885 | 528 | T>I | No | 1000Genomes | |
| ENSVATH06413107 | 553 | T>M | No | 1000Genomes | |
| ENSVATH10493692 | 582 | T>I | No | 1000Genomes | |
| ENSVATH02610267 | 584 | S>C | No | 1000Genomes | |
| ENSVATH10493690 | 636 | I>L | No | 1000Genomes | |
| tmp_4_573327_G_A | 663 | A>V | No | 1000Genomes | |
| ENSVATH06413105 | 688 | T>M | No | 1000Genomes | |
| ENSVATH13870750 | 731 | E>Q | No | 1000Genomes | |
| tmp_4_573112_C_T | 735 | A>T | No | 1000Genomes |
No associated diseases with Q8L838
1 regional properties for Q8L838
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Conserved oligomeric Golgi complex, subunit 4 | 176 - 480 | IPR013167 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
31 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q06096 | COG4 | Conserved oligomeric Golgi complex subunit 4 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q3MHG0 | COG4 | Conserved oligomeric Golgi complex subunit 4 | Bos taurus (Bovine) | PR |
| Q95TN4 | Cog4 | Conserved oligomeric Golgi complex subunit 4 | Drosophila melanogaster (Fruit fly) | PR |
| Q9NX36 | DNAJC28 | DnaJ homolog subfamily C member 28 | Homo sapiens (Human) | PR |
| Q9H9E3 | COG4 | Conserved oligomeric Golgi complex subunit 4 | Homo sapiens (Human) | PR |
| Q8R1U1 | Cog4 | Conserved oligomeric Golgi complex subunit 4 | Mus musculus (Mouse) | PR |
| Q9C7F1 | At1g28020 | Putative pentatricopeptide repeat-containing protein At1g28020 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C545 | At1g43010 | Putative pentatricopeptide repeat-containing protein At1g43010 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3ECH5 | At1g66345 | Pentatricopeptide repeat-containing protein At1g66345, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9CA73 | PCMP-E68 | Putative pentatricopeptide repeat-containing protein At1g74400 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GW57 | At1g80150 | Pentatricopeptide repeat-containing protein At1g80150, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56XX3 | At2g02148 | Uncharacterized protein At2g02148 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0C894 | At2g02150 | Putative pentatricopeptide repeat-containing protein At2g02150 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZU67 | At2g18520 | Pentatricopeptide repeat-containing protein At2g18520, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8S8Q7 | PCMP-H25 | Pentatricopeptide repeat-containing protein At2g34370, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8L6Y7 | At2g38420 | Pentatricopeptide repeat-containing protein At2g38420, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M891 | At3g02490 | Pentatricopeptide repeat-containing protein At3g02490, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LK58 | At3g13150 | Pentatricopeptide repeat-containing protein At3g13150 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M2C8 | At3g61360 | Pentatricopeptide repeat-containing protein At3g61360 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZP3 | At3g62470 | Pentatricopeptide repeat-containing protein At3g62470, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3EAF8 | At3g62540 | Pentatricopeptide repeat-containing protein At3g62540, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M4P3 | DYW10 | Pentatricopeptide repeat-containing protein At4g16835, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SVH3 | At4g20740 | Pentatricopeptide repeat-containing protein At4g20740 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O49711 | At4g21880 | Pentatricopeptide repeat-containing protein At4g21880, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SZL5 | At4g38150 | Pentatricopeptide repeat-containing protein At4g38150 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZ19 | PCMP-H16 | Pentatricopeptide repeat-containing protein At5g04780, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LEQ7 | At5g14820 | Pentatricopeptide repeat-containing protein At5g14820, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LFQ4 | At5g15010 | Pentatricopeptide repeat-containing protein At5g15010, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LXF4 | At5g15280 | Pentatricopeptide repeat-containing protein At5g15280, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FLJ6 | At5g61370 | Pentatricopeptide repeat-containing protein At5g61370, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FJY7 | PCMP-H61 | Pentatricopeptide repeat-containing protein At5g66520 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPEIEQDDAA | AETVDSSTVK | FGTPEALEYV | RSLTDVGAMT | RLLHECIAYQ | RSLDSDLDTL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LSQRTELDRN | LVQLQRSAEI | LDIVKADADH | MLGNVRSTCD | LADQVSGKVR | ELDLAQSRVN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VTLSRIDAIV | ERGNCIEGVK | TALESEDYES | AAKFVQRFLQ | IDLQYKDSGS | DQSEQLHASK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EQLEGIAKKK | LLAAIDQRDH | PTILRFVRLY | SPLGMETEGL | QLYVGYLKKV | IALRGRMEYE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NVVELMEQGL | GQVNFVGCLT | NLFKDIVMAI | EENDEILRGL | CGEDGVAYAI | CELQEECDLR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GSLILKKYMD | FRKLAILASD | INNSPNLNIL | PGGASEGPDP | REVELYVEEI | LSLMQLGEDY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TEFMVSKIKS | LTSVDPELLP | TATKAFRNKS | FSKAIQDVTR | YYVILEGFFM | VENVRKAIRI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DEHVPDSLTT | SMVDDVFYVL | QSCLRRAIST | SNISSVIAVL | SYAGSLLGND | YHEALQQKIR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EPNLGARLFL | GGIGVENTGT | EIATALNNMD | VSCEYILKLK | HEIEEQCTEV | FPAPADRERI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KSCLSELGEL | SSTFKQLLNS | GMEQLVATVT | PRIRPVLDTV | ATISYELTET | EYAENEVNDP |
| 610 | 620 | 630 | 640 | 650 | 660 |
| WVQRLLHSVE | TNAAWLQPLM | TSNNYDSFLH | LIIDFIVKRL | EVIMMQKRFS | QLGGLQLDRD |
| 670 | 680 | 690 | 700 | 710 | 720 |
| TRALVSHFSG | MTQRTVRDKF | ARLTQMATIL | NLEKVSEILD | FWGENSGPMT | WRLTPAEVRR |
| 730 | |||||
| VLGLRVEFKP | ESIAALKL |