Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P0C894

Entry ID Method Resolution Chain Position Source
AF-P0C894-F1 Predicted AlphaFoldDB

77 variants for P0C894

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_552567_C_T 20 S>N No 1000Genomes
ENSVATH01612013 22 S>C No 1000Genomes
ENSVATH01612009 34 C>Y No 1000Genomes
tmp_2_552522_A_T 35 F>Y No 1000Genomes
tmp_2_552472_A_C 52 F>V No 1000Genomes
tmp_2_552451_G_C 59 L>V No 1000Genomes
tmp_2_552408_G_T 73 S>Y No 1000Genomes
ENSVATH05214528 89 H>Q No 1000Genomes
tmp_2_552353_A_T 91 D>E No 1000Genomes
ENSVATH10613691 99 E>G No 1000Genomes
ENSVATH01612008 99 E>K No 1000Genomes
tmp_2_552308_T_A 106 L>F No 1000Genomes
tmp_2_552277_C_G 117 E>Q No 1000Genomes
tmp_2_552239_G_C 129 F>L No 1000Genomes
tmp_2_552225_G_C 134 T>S No 1000Genomes
tmp_2_552162_G_A 155 A>V No 1000Genomes
tmp_2_552144_G_A 161 A>V No 1000Genomes
ENSVATH05214527 163 S>C No 1000Genomes
tmp_2_552127_C_G 167 E>Q No 1000Genomes
tmp_2_552106_C_T 174 D>N No 1000Genomes
ENSVATH10613688 176 D>H No 1000Genomes
tmp_2_552075_G_T 184 T>K No 1000Genomes
ENSVATH01612006 188 C>G No 1000Genomes
ENSVATH01612006 188 C>R No 1000Genomes
ENSVATH13872788 189 V>G No 1000Genomes
ENSVATH05214526 189 V>L No 1000Genomes
tmp_2_552048_C_A 193 G>V No 1000Genomes
ENSVATH05214524 223 V>I No 1000Genomes
ENSVATH00201714 258 A>S No 1000Genomes
tmp_2_551853_G_A 258 A>V No 1000Genomes
tmp_2_551847_G_T 260 P>Q No 1000Genomes
ENSVATH01612005 260 P>T No 1000Genomes
ENSVATH10613687 262 V>A No 1000Genomes
ENSVATH10613686 268 M>I No 1000Genomes
ENSVATH05214520 287 E>D No 1000Genomes
tmp_2_551685_T_A 314 D>V No 1000Genomes
tmp_2_551548_C_T 360 G>R No 1000Genomes
ENSVATH10613554 370 Y>C No 1000Genomes
tmp_2_551436_C_T 397 G>D No 1000Genomes
ENSVATH10613553 404 T>I No 1000Genomes
tmp_2_551328_A_T 433 V>E No 1000Genomes
ENSVATH05214515 445 D>H No 1000Genomes
ENSVATH10613552 465 T>P No 1000Genomes
tmp_2_551173_C_A 485 A>S No 1000Genomes
tmp_2_551172_G_A 485 A>V No 1000Genomes
tmp_2_551164_T_A 488 M>L No 1000Genomes
tmp_2_551137_C_G 497 E>Q No 1000Genomes
tmp_2_551064_T_A 521 E>V No 1000Genomes
ENSVATH13872786 532 E>Q No 1000Genomes
tmp_2_551029_T_G 533 M>L No 1000Genomes
tmp_2_550995_A_C 544 I>S No 1000Genomes
tmp_2_550975_C_A 551 A>S No 1000Genomes
tmp_2_550972_A_G 552 Y>H No 1000Genomes
ENSVATH10613549 555 S>L No 1000Genomes
ENSVATH00201711 558 P>Q No 1000Genomes
ENSVATH10613548 560 E>A No 1000Genomes
ENSVATH05214510 563 H>Y No 1000Genomes
ENSVATH10613547 600 F>L No 1000Genomes
ENSVATH00201710 607 F>S No 1000Genomes
ENSVATH01612003 610 Q>H No 1000Genomes
tmp_2_550797_T_A 610 Q>L No 1000Genomes
ENSVATH00201709 611 A>G No 1000Genomes
tmp_2_550762_C_T 622 G>S No 1000Genomes
ENSVATH00201708 624 C>G No 1000Genomes
tmp_2_550728_G_A 633 T>I No 1000Genomes
tmp_2_550699_C_T 643 G>R No 1000Genomes
ENSVATH05214508 652 T>S No 1000Genomes
ENSVATH01612002 681 L>F No 1000Genomes
ENSVATH05214504 710 I>M No 1000Genomes
ENSVATH05214503 711 G>W No 1000Genomes
ENSVATH01612001 722 I>S No 1000Genomes
tmp_2_550459_T_C 723 S>G No 1000Genomes
ENSVATH00201706 733 C>Y No 1000Genomes
ENSVATH05214502 736 E>K No 1000Genomes
ENSVATH05214501 738 V>L No 1000Genomes
ENSVATH10613546 747 H>Y No 1000Genomes
ENSVATH05214500 758 L>F No 1000Genomes

No associated diseases with P0C894

9 regional properties for P0C894

Type Name Position InterPro Accession
repeat Pentatricopeptide repeat 196 - 222 IPR002885-1
repeat Pentatricopeptide repeat 226 - 261 IPR002885-2
repeat Pentatricopeptide repeat 260 - 367 IPR002885-3
repeat Pentatricopeptide repeat 365 - 471 IPR002885-4
repeat Pentatricopeptide repeat 470 - 506 IPR002885-5
repeat Pentatricopeptide repeat 506 - 540 IPR002885-6
repeat Pentatricopeptide repeat 541 - 606 IPR002885-7
repeat Pentatricopeptide repeat 612 - 681 IPR002885-8
repeat Pentatricopeptide repeat 682 - 718 IPR002885-9

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
pre-mRNA binding Binding to a pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.

1 GO annotations of biological process

Name Definition
mitochondrial mRNA processing Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.

25 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9C7F1 At1g28020 Putative pentatricopeptide repeat-containing protein At1g28020 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C545 At1g43010 Putative pentatricopeptide repeat-containing protein At1g43010 Arabidopsis thaliana (Mouse-ear cress) PR
Q9CA73 PCMP-E68 Putative pentatricopeptide repeat-containing protein At1g74400 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GW57 At1g80150 Pentatricopeptide repeat-containing protein At1g80150, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q56XX3 At2g02148 Uncharacterized protein At2g02148 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZU67 At2g18520 Pentatricopeptide repeat-containing protein At2g18520, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q8S8Q7 PCMP-H25 Pentatricopeptide repeat-containing protein At2g34370, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q8L6Y7 At2g38420 Pentatricopeptide repeat-containing protein At2g38420, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9M891 At3g02490 Pentatricopeptide repeat-containing protein At3g02490, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LK58 At3g13150 Pentatricopeptide repeat-containing protein At3g13150 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LZP3 At3g62470 Pentatricopeptide repeat-containing protein At3g62470, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q3EAF8 At3g62540 Pentatricopeptide repeat-containing protein At3g62540, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q8L838 COG4 Conserved oligomeric Golgi complex subunit 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M4P3 DYW10 Pentatricopeptide repeat-containing protein At4g16835, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9SVH3 At4g20740 Pentatricopeptide repeat-containing protein At4g20740 Arabidopsis thaliana (Mouse-ear cress) PR
O49711 At4g21880 Pentatricopeptide repeat-containing protein At4g21880, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9SZL5 At4g38150 Pentatricopeptide repeat-containing protein At4g38150 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LZ19 PCMP-H16 Pentatricopeptide repeat-containing protein At5g04780, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LEQ7 At5g14820 Pentatricopeptide repeat-containing protein At5g14820, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LXF4 At5g15280 Pentatricopeptide repeat-containing protein At5g15280, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9FLJ6 At5g61370 Pentatricopeptide repeat-containing protein At5g61370, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJY7 PCMP-H61 Pentatricopeptide repeat-containing protein At5g66520 Arabidopsis thaliana (Mouse-ear cress) PR
Q3ECH5 At1g66345 Pentatricopeptide repeat-containing protein At1g66345, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LFQ4 At5g15010 Pentatricopeptide repeat-containing protein At5g15010, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2C8 At3g61360 Pentatricopeptide repeat-containing protein At3g61360 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MFCSLRNFLH VNRRFPRHVS PSSSSLSQIQ SPLCFPLSSP SPSQSSFISC PFVWFTSFLC
70 80 90 100 110 120
IIRYPFVTKS GTSTYSEDFD RDWIRKVVHN DLWDDPGLEK LFDLTLAPIW VPRVLVELKE
130 140 150 160 170 180
DPKLAFKFFK WSMTRNGFKH SVESYCIVAH ILFCARMYYD ANSVLKEMVL SKADCDVFDV
190 200 210 220 230 240
LWSTRNVCVP GFGVFDALFS VLIDLGMLEE AIQCFSKMKR FRVFPKTRSC NGLLHRFAKL
250 260 270 280 290 300
GKTDDVKRFF KDMIGAGARP TVFTYNIMID CMCKEGDVEA ARGLFEEMKF RGLVPDTVTY
310 320 330 340 350 360
NSMIDGFGKV GRLDDTVCFF EEMKDMCCEP DVITYNALIN CFCKFGKLPI GLEFYREMKG
370 380 390 400 410 420
NGLKPNVVSY STLVDAFCKE GMMQQAIKFY VDMRRVGLVP NEYTYTSLID ANCKIGNLSD
430 440 450 460 470 480
AFRLGNEMLQ VGVEWNVVTY TALIDGLCDA ERMKEAEELF GKMDTAGVIP NLASYNALIH
490 500 510 520 530 540
GFVKAKNMDR ALELLNELKG RGIKPDLLLY GTFIWGLCSL EKIEAAKVVM NEMKECGIKA
550 560 570 580 590 600
NSLIYTTLMD AYFKSGNPTE GLHLLDEMKE LDIEVTVVTF CVLIDGLCKN KLVSKAVDYF
610 620 630 640 650 660
NRISNDFGLQ ANAAIFTAMI DGLCKDNQVE AATTLFEQMV QKGLVPDRTA YTSLMDGNFK
670 680 690 700 710 720
QGNVLEALAL RDKMAEIGMK LDLLAYTSLV WGLSHCNQLQ KARSFLEEMI GEGIHPDEVL
730 740 750 760
CISVLKKHYE LGCIDEAVEL QSYLMKHQLL TSDNDNALPN M