Q8S8Q7

PR
Gene name
PCMP-H25 (PCMP-H62, At2g34370, F13P17.21, T31E10)
Protein name
Pentatricopeptide repeat-containing protein At2g34370, mitochondrial
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G34370
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

285-354 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8S8Q7

Entry ID Method Resolution Chain Position Source
AF-Q8S8Q7-F1 Predicted AlphaFoldDB

74 variants for Q8S8Q7

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05654832 5 V>G No 1000Genomes
ENSVATH05654831 5 V>I No 1000Genomes
ENSVATH01947003 15 P>Q No 1000Genomes
tmp_2_14510528_A_T 16 Y>F No 1000Genomes
ENSVATH05654833 18 W>R No 1000Genomes
ENSVATH13527434 31 R>Q No 1000Genomes
ENSVATH14584212 37 L>V No 1000Genomes
ENSVATH05654834 39 T>K No 1000Genomes
ENSVATH00259651 40 K>N No 1000Genomes
ENSVATH05654836 44 S>L No 1000Genomes
ENSVATH05654837 45 S>F No 1000Genomes
tmp_2_14510631_A_C 50 L>F No 1000Genomes
ENSVATH01947005 52 R>H No 1000Genomes
tmp_2_14510669_G_C 63 C>S No 1000Genomes
tmp_2_14510675_G_T 65 R>I No 1000Genomes
tmp_2_14510680_T_G 67 S>A No 1000Genomes
tmp_2_14510722_A_G 81 I>V No 1000Genomes
tmp_2_14510734_G_T 85 D>Y No 1000Genomes
ENSVATH05654838 88 C>R No 1000Genomes
ENSVATH13527446 109 I>T No 1000Genomes
tmp_2_14510810_T_C 110 V>A No 1000Genomes
tmp_2_14510878_G_T 133 V>F No 1000Genomes
tmp_2_14510891_G_A 137 C>Y No 1000Genomes
ENSVATH05654840 164 N>I No 1000Genomes
ENSVATH05654841 166 F>L No 1000Genomes
ENSVATH01947007 172 R>G No 1000Genomes
ENSVATH01947008 175 E>* No 1000Genomes
ENSVATH01947009 179 T>I No 1000Genomes
tmp_2_14511074_C_T 198 T>M No 1000Genomes
ENSVATH01947010 202 E>G No 1000Genomes
ENSVATH00259653 215 V>A No 1000Genomes
tmp_2_14511204_G_T 241 M>I No 1000Genomes
ENSVATH01947012 243 L>P No 1000Genomes
ENSVATH01947015 252 I>T No 1000Genomes
ENSVATH13527449 262 D>E No 1000Genomes
ENSVATH01947016 266 D>E No 1000Genomes
ENSVATH01947017 268 V>I No 1000Genomes
ENSVATH01947018 269 E>D No 1000Genomes
ENSVATH01947019 272 T>N No 1000Genomes
ENSVATH01947021 273 V>A No 1000Genomes
ENSVATH01947023 290 Q>H No 1000Genomes
ENSVATH01947024 291 G>E No 1000Genomes
ENSVATH13527450 291 G>R No 1000Genomes
ENSVATH01947026 292 Y>* No 1000Genomes
ENSVATH01947025 292 Y>D No 1000Genomes
tmp_2_14511377_T_C 299 F>S No 1000Genomes
tmp_2_14511379_G_C 300 A>P No 1000Genomes
ENSVATH01947029 303 I>M No 1000Genomes
ENSVATH01947028 303 I>V No 1000Genomes
tmp_2_14511412_A_C 311 M>L No 1000Genomes
ENSVATH01947031 312 S>N No 1000Genomes
ENSVATH05654843 312 S>R No 1000Genomes
tmp_2_14511419_A_C 313 K>T No 1000Genomes
ENSVATH01947032 325 S>L No 1000Genomes
tmp_2_14511457_G_T 326 D>Y No 1000Genomes
ENSVATH05654844 328 A>T No 1000Genomes
ENSVATH01947033 329 M>K No 1000Genomes
ENSVATH01947034 330 E>K No 1000Genomes
tmp_2_14511475_C_G 332 L>V No 1000Genomes
tmp_2_14511481_G_A 334 E>K No 1000Genomes
ENSVATH00259654 347 K>N No 1000Genomes
ENSVATH05654846 360 L>R No 1000Genomes
ENSVATH13527476 363 V>D No 1000Genomes
ENSVATH00259655 366 F>L No 1000Genomes
tmp_2_14511592_G_C 371 V>L No 1000Genomes
ENSVATH05654847 398 L>F No 1000Genomes
ENSVATH05654848 404 K>* No 1000Genomes
ENSVATH05654849 415 E>K No 1000Genomes
tmp_2_14511736_C_T 419 P>S No 1000Genomes
tmp_2_14511746_T_G 422 V>G No 1000Genomes
ENSVATH05654850 445 R>I No 1000Genomes
ENSVATH01947035 454 K>E No 1000Genomes
tmp_2_14511844_T_A 455 Y>N No 1000Genomes
ENSVATH00259657 468 Y>F No 1000Genomes

No associated diseases with Q8S8Q7

4 regional properties for Q8S8Q7

Type Name Position InterPro Accession
repeat Pentatricopeptide repeat 142 - 173 IPR002885-1
repeat Pentatricopeptide repeat 173 - 208 IPR002885-2
repeat Pentatricopeptide repeat 248 - 272 IPR002885-3
domain DYW domain 377 - 469 IPR032867

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
RNA modification The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.

25 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9C7F1 At1g28020 Putative pentatricopeptide repeat-containing protein At1g28020 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C545 At1g43010 Putative pentatricopeptide repeat-containing protein At1g43010 Arabidopsis thaliana (Mouse-ear cress) PR
Q3ECH5 At1g66345 Pentatricopeptide repeat-containing protein At1g66345, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9CA73 PCMP-E68 Putative pentatricopeptide repeat-containing protein At1g74400 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GW57 At1g80150 Pentatricopeptide repeat-containing protein At1g80150, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q56XX3 At2g02148 Uncharacterized protein At2g02148 Arabidopsis thaliana (Mouse-ear cress) PR
P0C894 At2g02150 Putative pentatricopeptide repeat-containing protein At2g02150 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZU67 At2g18520 Pentatricopeptide repeat-containing protein At2g18520, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q8L6Y7 At2g38420 Pentatricopeptide repeat-containing protein At2g38420, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9M891 At3g02490 Pentatricopeptide repeat-containing protein At3g02490, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LK58 At3g13150 Pentatricopeptide repeat-containing protein At3g13150 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2C8 At3g61360 Pentatricopeptide repeat-containing protein At3g61360 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LZP3 At3g62470 Pentatricopeptide repeat-containing protein At3g62470, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q3EAF8 At3g62540 Pentatricopeptide repeat-containing protein At3g62540, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q8L838 COG4 Conserved oligomeric Golgi complex subunit 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M4P3 DYW10 Pentatricopeptide repeat-containing protein At4g16835, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9SVH3 At4g20740 Pentatricopeptide repeat-containing protein At4g20740 Arabidopsis thaliana (Mouse-ear cress) PR
O49711 At4g21880 Pentatricopeptide repeat-containing protein At4g21880, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9SZL5 At4g38150 Pentatricopeptide repeat-containing protein At4g38150 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LEQ7 At5g14820 Pentatricopeptide repeat-containing protein At5g14820, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LFQ4 At5g15010 Pentatricopeptide repeat-containing protein At5g15010, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LXF4 At5g15280 Pentatricopeptide repeat-containing protein At5g15280, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9FLJ6 At5g61370 Pentatricopeptide repeat-containing protein At5g61370, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJY7 PCMP-H61 Pentatricopeptide repeat-containing protein At5g66520 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LZ19 PCMP-H16 Pentatricopeptide repeat-containing protein At5g04780, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVRLVCSRIL KFPKPYLWSA TQTTSRCFNS RAQSHNLITK TITSSLQDVL TRPIWQNRSF
70 80 90 100 110 120
VQCRRVSSYA QMVNNHQSVT IETFDALCKQ VKIREALEVI DILEDKGYIV DFPRLLGLAK
130 140 150 160 170 180
LCGEVEALEE ARVVHDCITP LDARSYHTVI EMYSGCRSTD DALNVFNEMP KRNSETWGTM
190 200 210 220 230 240
IRCLAKNGEG ERAIDMFTRF IEEGNKPDKE IFKAVFFACV SIGDINEGLL HFESMYRDYG
250 260 270 280 290 300
MVLSMEDYVN VIEMLAACGH LDEALDFVER MTVEPSVEMW ETLMNLCWVQ GYLELGDRFA
310 320 330 340 350 360
ELIKKLDASR MSKESNAGLV AAKASDSAME KLKELRYCQM IRDDPKKRMH EFRAGDTSHL
370 380 390 400 410 420
GTVSAFRSLK VQMLDIGFVP ATRVCFVTVE EEEKEEQLLF RSNKLAFAHA IINSEARRPL
430 440 450 460
TVLQNMRTCI DGHNTFKMIS LITGRALIQR DKKKYHFYKN GVCSCKDYW