Q3ECH5
PR
Gene name |
At1g66345 (T27F4.19) |
Protein name |
Pentatricopeptide repeat-containing protein At1g66345, mitochondrial |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G66345 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3ECH5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3ECH5-F1 | Predicted | AlphaFoldDB |
126 variants for Q3ECH5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH13744912 | 6 | R>P | No | 1000Genomes | |
| ENSVATH05079594 | 12 | Q>R | No | 1000Genomes | |
| ENSVATH05079595 | 13 | Q>R | No | 1000Genomes | |
| ENSVATH05079596 | 23 | R>Q | No | 1000Genomes | |
| tmp_1_24737789_C_G | 24 | S>C | No | 1000Genomes | |
| tmp_1_24737788_T_A | 24 | S>T | No | 1000Genomes | |
| ENSVATH13744913 | 25 | P>Q | No | 1000Genomes | |
| tmp_1_24737816_C_A | 33 | S>Y | No | 1000Genomes | |
| ENSVATH01481567 | 34 | F>L | No | 1000Genomes | |
| ENSVATH05079597 | 41 | N>I | No | 1000Genomes | |
| tmp_1_24737869_G_A | 51 | D>N | No | 1000Genomes | |
| tmp_1_24737894_C_A,T | 59 | S>F | No | 1000Genomes | |
| tmp_1_24737894_C_A,T | 59 | S>Y | No | 1000Genomes | |
| ENSVATH00126264 | 61 | D>E | No | 1000Genomes | |
| ENSVATH05079598 | 64 | E>Q | No | 1000Genomes | |
| ENSVATH05079601 | 73 | I>M | No | 1000Genomes | |
| tmp_1_24737936_T_C | 73 | I>T | No | 1000Genomes | |
| ENSVATH05079600 | 73 | I>V | No | 1000Genomes | |
| tmp_1_24737974_C_G | 86 | R>G | No | 1000Genomes | |
| ENSVATH01481568 | 101 | H>Y | No | 1000Genomes | |
| tmp_1_24738035_C_T | 106 | T>I | No | 1000Genomes | |
| ENSVATH14428584 | 134 | A>T | No | 1000Genomes | |
| tmp_1_24738141_A_C | 141 | L>F | No | 1000Genomes | |
| ENSVATH05079604 | 142 | N>I | No | 1000Genomes | |
| tmp_1_24738144_T_G | 142 | N>K | No | 1000Genomes | |
| ENSVATH05079603 | 142 | N>Y | No | 1000Genomes | |
| ENSVATH01481569 | 157 | Y>S | No | 1000Genomes | |
| ENSVATH01481570 | 165 | L>F | No | 1000Genomes | |
| ENSVATH01481571 | 170 | L>I | No | 1000Genomes | |
| ENSVATH01481571 | 170 | L>V | No | 1000Genomes | |
| ENSVATH01481572 | 192 | D>Y | No | 1000Genomes | |
| tmp_1_24738362_A_G | 215 | D>G | No | 1000Genomes | |
| ENSVATH05079606 | 228 | K>R | No | 1000Genomes | |
| ENSVATH05079607 | 238 | R>W | No | 1000Genomes | |
| ENSVATH01481573 | 242 | Q>E | No | 1000Genomes | |
| tmp_1_24738523_G_A | 269 | V>M | No | 1000Genomes | |
| ENSVATH13744918 | 294 | R>K | No | 1000Genomes | |
| tmp_1_24738656_C_T | 313 | A>V | No | 1000Genomes | |
| tmp_1_24738675_T_G | 319 | D>E | No | 1000Genomes | |
| tmp_1_24738693_G_C | 325 | K>N | No | 1000Genomes | |
| tmp_1_24738695_T_C | 326 | V>A | No | 1000Genomes | |
| ENSVATH13744920 | 334 | G>S | No | 1000Genomes | |
| ENSVATH01481575 | 337 | A>V | No | 1000Genomes | |
| tmp_1_24738746_C_T | 343 | T>M | No | 1000Genomes | |
| tmp_1_24738754_G_T | 346 | V>F | No | 1000Genomes | |
| tmp_1_24738782_T_A | 355 | V>D | No | 1000Genomes | |
| ENSVATH05079612 | 355 | V>I | No | 1000Genomes | |
| ENSVATH01481576 | 356 | K>E | No | 1000Genomes | |
| ENSVATH13744921 | 362 | L>F | No | 1000Genomes | |
| ENSVATH13744922 | 363 | S>T | No | 1000Genomes | |
| ENSVATH05079613 | 364 | E>A | No | 1000Genomes | |
| tmp_1_24738817_G_A | 367 | E>K | No | 1000Genomes | |
| ENSVATH14428588 | 372 | P>S | No | 1000Genomes | |
| ENSVATH05079615 | 376 | T>M | No | 1000Genomes | |
| tmp_1_24738851_A_G | 378 | N>S | No | 1000Genomes | |
| ENSVATH05079616 | 382 | G>D | No | 1000Genomes | |
| tmp_1_24738862_G_A | 382 | G>S | No | 1000Genomes | |
| tmp_1_24738913_G_A | 399 | V>I | No | 1000Genomes | |
| ENSVATH05079619 | 402 | T>K | No | 1000Genomes | |
| ENSVATH13744923 | 403 | R>K | No | 1000Genomes | |
| ENSVATH01481579 | 405 | L>F | No | 1000Genomes | |
| tmp_1_24738949_G_A | 411 | A>T | No | 1000Genomes | |
| ENSVATH05079623 | 413 | N>S | No | 1000Genomes | |
| ENSVATH00126269 | 418 | S>C | No | 1000Genomes | |
| tmp_1_24738972_T_A | 418 | S>R | No | 1000Genomes | |
| tmp_1_24738977_G_A | 420 | S>N | No | 1000Genomes | |
| tmp_1_24738985_G_A | 423 | E>K | No | 1000Genomes | |
| ENSVATH01481582 | 426 | N>K | No | 1000Genomes | |
| ENSVATH00126270 | 428 | A>T | No | 1000Genomes | |
| ENSVATH14428590 | 429 | N>D | No | 1000Genomes | |
| ENSVATH01481585 | 430 | E>A | No | 1000Genomes | |
| tmp_1_24739009_A_G | 431 | I>V | No | 1000Genomes | |
| ENSVATH05079624 | 432 | L>I | No | 1000Genomes | |
| ENSVATH05079625 | 434 | K>N | No | 1000Genomes | |
| ENSVATH01481587 | 435 | S>A | No | 1000Genomes | |
| ENSVATH14428591 | 435 | S>L | No | 1000Genomes | |
| ENSVATH01481587 | 435 | S>T | No | 1000Genomes | |
| ENSVATH05079626 | 437 | D>E | No | 1000Genomes | |
| ENSVATH07681250 | 438 | K>N | No | 1000Genomes | |
| ENSVATH07681249 | 438 | K>Q | No | 1000Genomes | |
| tmp_1_24739042_C_G | 442 | P>A | No | 1000Genomes | |
| tmp_1_24739043_C_A | 442 | P>H | No | 1000Genomes | |
| ENSVATH01481588 | 443 | D>H | No | 1000Genomes | |
| ENSVATH05079627 | 445 | H>L | No | 1000Genomes | |
| ENSVATH05079628 | 445 | H>Q | No | 1000Genomes | |
| tmp_1_24739063_C_T | 449 | H>Y | No | 1000Genomes | |
| tmp_1_24739072_C_G | 452 | R>G | No | 1000Genomes | |
| ENSVATH13744924 | 452 | R>L | No | 1000Genomes | |
| ENSVATH13744924 | 452 | R>Q | No | 1000Genomes | |
| ENSVATH01481590 | 455 | I>V | No | 1000Genomes | |
| ENSVATH13744925 | 456 | E>K | No | 1000Genomes | |
| tmp_1_24739097_T_C | 460 | I>T | No | 1000Genomes | |
| ENSVATH05079631 | 461 | D>A | No | 1000Genomes | |
| ENSVATH05079631 | 461 | D>G | No | 1000Genomes | |
| tmp_1_24739102_C_G | 462 | Q>E | No | 1000Genomes | |
| ENSVATH13744926 | 463 | A>V | No | 1000Genomes | |
| ENSVATH13744927 | 470 | M>I | No | 1000Genomes | |
| ENSVATH05079632 | 473 | R>Q | No | 1000Genomes | |
| ENSVATH00126271 | 476 | S>C | No | 1000Genomes | |
| ENSVATH05079633 | 479 | F>V | No | 1000Genomes | |
| tmp_1_24739157_A_G | 480 | E>G | No | 1000Genomes | |
| ENSVATH01481593 | 483 | R>K | No | 1000Genomes | |
| tmp_1_24739167_G_C | 483 | R>S | No | 1000Genomes | |
| tmp_1_24739177_G_A | 487 | V>M | No | 1000Genomes | |
| ENSVATH13744928 | 489 | L>H | No | 1000Genomes | |
| ENSVATH01481595 | 491 | T>A | No | 1000Genomes | |
| ENSVATH13744929 | 492 | C>W | No | 1000Genomes | |
| ENSVATH00126273 | 494 | K>E | No | 1000Genomes | |
| ENSVATH01481596 | 502 | L>W | No | 1000Genomes | |
| ENSVATH05079634 | 503 | K>N | No | 1000Genomes | |
| ENSVATH01481597 | 503 | K>R | No | 1000Genomes | |
| ENSVATH01481598 | 504 | I>T | No | 1000Genomes | |
| ENSVATH01481599 | 507 | K>R | No | 1000Genomes | |
| tmp_1_24739246_A_G | 510 | I>V | No | 1000Genomes | |
| ENSVATH13744930 | 514 | A>E | No | 1000Genomes | |
| tmp_1_24739262_A_T | 515 | D>V | No | 1000Genomes | |
| ENSVATH01481600 | 517 | Y>F | No | 1000Genomes | |
| ENSVATH01481601 | 518 | D>E | No | 1000Genomes | |
| ENSVATH01481602 | 519 | A>V | No | 1000Genomes | |
| ENSVATH05079635 | 522 | K>R | No | 1000Genomes | |
| ENSVATH00126274 | 526 | K>I | No | 1000Genomes | |
| ENSVATH01481604 | 530 | K>N | No | 1000Genomes | |
| tmp_1_24739320_T_G | 534 | D>E | No | 1000Genomes | |
| ENSVATH01481605 | 538 | N>D | No | 1000Genomes | |
| ENSVATH01481606 | 543 | V>I | No | 1000Genomes | |
| ENSVATH13744931 | 545 | R>C | No | 1000Genomes |
No associated diseases with Q3ECH5
6 regional properties for Q3ECH5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Pentatricopeptide repeat | 233 - 268 | IPR002885-1 |
| repeat | Pentatricopeptide repeat | 303 - 338 | IPR002885-2 |
| repeat | Pentatricopeptide repeat | 338 - 409 | IPR002885-3 |
| repeat | Pentatricopeptide repeat | 443 - 477 | IPR002885-4 |
| repeat | Pentatricopeptide repeat | 478 - 512 | IPR002885-5 |
| domain | Pentacotripeptide-repeat region of PRORP | 409 - 540 | IPR033443 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| Group II intron splicing | The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. |
| mitochondrial respiratory chain complex I assembly | The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I. |
| mitochondrial RNA processing | The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion. |
25 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9C7F1 | At1g28020 | Putative pentatricopeptide repeat-containing protein At1g28020 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C545 | At1g43010 | Putative pentatricopeptide repeat-containing protein At1g43010 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9CA73 | PCMP-E68 | Putative pentatricopeptide repeat-containing protein At1g74400 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GW57 | At1g80150 | Pentatricopeptide repeat-containing protein At1g80150, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56XX3 | At2g02148 | Uncharacterized protein At2g02148 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZU67 | At2g18520 | Pentatricopeptide repeat-containing protein At2g18520, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8S8Q7 | PCMP-H25 | Pentatricopeptide repeat-containing protein At2g34370, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8L6Y7 | At2g38420 | Pentatricopeptide repeat-containing protein At2g38420, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M891 | At3g02490 | Pentatricopeptide repeat-containing protein At3g02490, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LK58 | At3g13150 | Pentatricopeptide repeat-containing protein At3g13150 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZP3 | At3g62470 | Pentatricopeptide repeat-containing protein At3g62470, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3EAF8 | At3g62540 | Pentatricopeptide repeat-containing protein At3g62540, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8L838 | COG4 | Conserved oligomeric Golgi complex subunit 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M4P3 | DYW10 | Pentatricopeptide repeat-containing protein At4g16835, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SVH3 | At4g20740 | Pentatricopeptide repeat-containing protein At4g20740 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O49711 | At4g21880 | Pentatricopeptide repeat-containing protein At4g21880, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SZL5 | At4g38150 | Pentatricopeptide repeat-containing protein At4g38150 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZ19 | PCMP-H16 | Pentatricopeptide repeat-containing protein At5g04780, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LEQ7 | At5g14820 | Pentatricopeptide repeat-containing protein At5g14820, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LXF4 | At5g15280 | Pentatricopeptide repeat-containing protein At5g15280, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FLJ6 | At5g61370 | Pentatricopeptide repeat-containing protein At5g61370, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FJY7 | PCMP-H61 | Pentatricopeptide repeat-containing protein At5g66520 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0C894 | At2g02150 | Putative pentatricopeptide repeat-containing protein At2g02150 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LFQ4 | At5g15010 | Pentatricopeptide repeat-containing protein At5g15010, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M2C8 | At3g61360 | Pentatricopeptide repeat-containing protein At3g61360 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASALRRLVE | QQQWRYLVSQ | STRSPKLIHG | FFSFSSKTNP | NPNKQQQILI | DYISKSLQSN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DTWETLSTKF | SSIDLSDSLI | ETILLRFKNP | ETAKQALSFF | HWSSHTRNLR | HGIKSYALTI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HILVKARLLI | DARALIESSL | LNSPPDSDLV | DSLLDTYEIS | SSTPLVFDLL | VQCYAKIRYL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ELGFDVFKRL | CDCGFTLSVI | TLNTLIHYSS | KSKIDDLVWR | IYECAIDKRI | YPNEITIRIM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IQVLCKEGRL | KEVVDLLDRI | CGKRCLPSVI | VNTSLVFRVL | EEMRIEESMS | LLKRLLMKNM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VVDTIGYSIV | VYAKAKEGDL | VSARKVFDEM | LQRGFSANSF | VYTVFVRVCC | EKGDVKEAER |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LLSEMEESGV | SPYDETFNCL | IGGFARFGWE | EKGLEYCEVM | VTRGLMPSCS | AFNEMVKSVS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KIENVNRANE | ILTKSIDKGF | VPDEHTYSHL | IRGFIEGNDI | DQALKLFYEM | EYRKMSPGFE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VFRSLIVGLC | TCGKVEAGEK | YLKIMKKRLI | EPNADIYDAL | IKAFQKIGDK | TNADRVYNEM |
| ISVR |