Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LRZ4

Entry ID Method Resolution Chain Position Source
AF-Q9LRZ4-F1 Predicted AlphaFoldDB

7 variants for Q9LRZ4

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05846265 44 N>K No 1000Genomes
tmp_3_5721442_C_G 50 T>S No 1000Genomes
tmp_3_5721766_A_G 92 T>A No 1000Genomes
ENSVATH05846269 135 E>G No 1000Genomes
ENSVATH05846270 164 I>V No 1000Genomes
tmp_3_5722616_C_T 282 T>I No 1000Genomes
ENSVATH13932751 310 G>E No 1000Genomes

No associated diseases with Q9LRZ4

1 regional properties for Q9LRZ4

Type Name Position InterPro Accession
domain PPM-type phosphatase-like domain 48 - 348 IPR001932

Functions

Description
EC Number 3.1.3.16 Phosphoric monoester hydrolases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
myosin phosphatase activity Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.
protein serine/threonine phosphatase activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.

5 GO annotations of biological process

Name Definition
drought recovery Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.
microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
negative regulation of growth Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
peptidyl-threonine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
protein dephosphorylation The process of removing one or more phosphoric residues from a protein.

35 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A5PJZ2 PPM1L Protein phosphatase 1L Bos taurus (Bovine) PR
P49593 PPM1F Protein phosphatase 1F Homo sapiens (Human) PR
Q5SGD2 PPM1L Protein phosphatase 1L Homo sapiens (Human) PR
O15297 PPM1D Protein phosphatase 1D Homo sapiens (Human) PR
Q8N819 PPM1N Probable protein phosphatase 1N Homo sapiens (Human) PR
Q8CGA0 Ppm1f Protein phosphatase 1F Mus musculus (Mouse) PR
Q8BHN0 Ppm1l Protein phosphatase 1L Mus musculus (Mouse) PR
Q80TL0 Ppm1e Protein phosphatase 1E Mus musculus (Mouse) PR
Q5JKN1 Os01g0552300 Probable protein phosphatase 2C 5 Oryza sativa subsp japonica (Rice) PR
Q0JLP9 PP2C06 Probable protein phosphatase 2C 6 Oryza sativa subsp japonica (Rice) PR
Q5SN75 Os01g0656200 Probable protein phosphatase 2C 8 Oryza sativa subsp japonica (Rice) PR
Q6K5I0 Os02g0600000 Probable protein phosphatase 2C 20 Oryza sativa subsp japonica (Rice) PR
Q7XW27 Os04g0321800 Probable protein phosphatase 2C 38 Oryza sativa subsp japonica (Rice) PR
Q6L4R7 PP2C53 Protein phosphatase 2C 53 Oryza sativa subsp japonica (Rice) PR
Q6ZKL8 Os08g0500300 Probable protein phosphatase 2C 66 Oryza sativa subsp japonica (Rice) PR
Q6L482 Os05g0358500 Probable protein phosphatase 2C 48 Oryza sativa subsp japonica (Rice) PR
Q9LMT1 At1g18030 Probable protein phosphatase 2C 8 Arabidopsis thaliana (Mouse-ear cress) PR
O81716 PPC4-2 Probable protein phosphatase 2C 21 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LDA7 At3g15260 Probable protein phosphatase 2C 39 Arabidopsis thaliana (Mouse-ear cress) PR
Q3EAZ3 At3g27140 Putative protein phosphatase 2C-like protein 45 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SD02 At3g51470 Probable protein phosphatase 2C 47 Arabidopsis thaliana (Mouse-ear cress) PR
P49599 PPH1 Protein phosphatase 2C 57 Arabidopsis thaliana (Mouse-ear cress) PR
Q94AT1 At5g53140 Probable protein phosphatase 2C 76 Arabidopsis thaliana (Mouse-ear cress) PR
O04719 ABI2 Protein phosphatase 2C 77 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GY60 At4g03415 Probable protein phosphatase 2C 52 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VZN9 At1g43900 Probable protein phosphatase 2C 11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9CAJ0 HAB1 Protein phosphatase 2C 16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FG61 At5g36250 Probable protein phosphatase 2C 74 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FIF5 SAG113 Probable protein phosphatase 2C 78 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LNP9 HAB2 Protein phosphatase 2C 7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LHJ9 PP2C38 Probable protein phosphatase 2C 38 Arabidopsis thaliana (Mouse-ear cress) PR
Q94CL8 PP2C6 Probable protein phosphatase 2C 48 Arabidopsis thaliana (Mouse-ear cress) PR
O81760 PP2C63 Probable protein phosphatase 2C 63 Arabidopsis thaliana (Mouse-ear cress) PR
Q501F9 PP2C67 Probable protein phosphatase 2C 67 Arabidopsis thaliana (Mouse-ear cress) PR
Q84JD5 PP2C68 Probable protein phosphatase 2C 68 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVLLPAFLDG LARTVSTKKG KKLSEDEDGG REIAKSMIKD SKKNSTLLGT SGFVSSESSK
70 80 90 100 110 120
RFTSICSNRG EKGINQDRAI VWEGFGCQED ITFCGMFDGH GPWGHVIAKR VKKSFPSSLL
130 140 150 160 170 180
CQWQQTLASL SSSPECSSPF DLWKQACLKT FSIIDLDLKI SPSIDSYCSG CTALTAVLQG
190 200 210 220 230 240
DHLVIANAGD SRAVIATTSD DGNGLVPVQL SVDFKPNIPE EAERIKQSDG RLFCLDDEPG
250 260 270 280 290 300
VYRVGMPNGG SLGLAVSRAF GDYCLKDFGL VSEPEVTYRK ITDKDQFLIL ATDGMWDVMT
310 320 330 340 350
NNEAVEIVRG VKERRKSAKR LVERAVTLWR RKRRSIAMDD ISVLCLFFRP S