Q9FIF5
PR
Gene name |
SAG113 |
Protein name |
Probable protein phosphatase 2C 78 |
Names |
AtPP2C78, Protein HIGHLY ABA-INDUCED 1, Protein SENESCENCE-ASSOCIATED GENE 113 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G59220 |
EC number |
3.1.3.16: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FIF5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FIF5-F1 | Predicted | AlphaFoldDB |
30 variants for Q9FIF5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_23896472_T_C | 9 | E>G | No | 1000Genomes | |
| ENSVATH12853795 | 12 | M>R | No | 1000Genomes | |
| ENSVATH12853754 | 29 | R>K | No | 1000Genomes | |
| tmp_5_23896349_A_G | 50 | F>S | No | 1000Genomes | |
| tmp_5_23896314_C_A | 62 | G>C | No | 1000Genomes | |
| ENSVATH14640446 | 82 | F>I | No | 1000Genomes | |
| ENSVATH00742113 | 87 | K>E | No | 1000Genomes | |
| ENSVATH07448729 | 92 | L>V | No | 1000Genomes | |
| ENSVATH03451265 | 97 | S>C | No | 1000Genomes | |
| ENSVATH03451264 | 114 | V>I | No | 1000Genomes | |
| tmp_5_23896116_C_T | 128 | V>I | No | 1000Genomes | |
| ENSVATH14640444 | 135 | S>P | No | 1000Genomes | |
| ENSVATH12853751 | 141 | Y>C | No | 1000Genomes | |
| tmp_5_23896062_A_C | 146 | F>V | No | 1000Genomes | |
| ENSVATH14640441 | 201 | N>D | No | 1000Genomes | |
| ENSVATH07448724 | 205 | A>V | No | 1000Genomes | |
| ENSVATH14640440 | 237 | A>G | No | 1000Genomes | |
| tmp_5_23895669_T_C | 249 | N>S | No | 1000Genomes | |
| tmp_5_23895231_G_T | 272 | A>E | No | 1000Genomes | |
| tmp_5_23894967_G_A | 316 | A>V | No | 1000Genomes | |
| tmp_5_23894964_T_C | 317 | N>S | No | 1000Genomes | |
| ENSVATH07448710 | 332 | V>I | No | 1000Genomes | |
| ENSVATH00742104 | 333 | V>I | No | 1000Genomes | |
| tmp_5_23894882_C_A | 344 | M>I | No | 1000Genomes | |
| ENSVATH07448709 | 354 | V>L | No | 1000Genomes | |
| ENSVATH03451241 | 367 | A>T | No | 1000Genomes | |
| tmp_5_23894788_C_G,T | 376 | D>H | No | 1000Genomes | |
| tmp_5_23894788_C_G,T | 376 | D>N | No | 1000Genomes | |
| tmp_5_23894721_C_T | 398 | S>N | No | 1000Genomes | |
| ENSVATH14640436 | 412 | D>E | No | 1000Genomes |
No associated diseases with Q9FIF5
1 regional properties for Q9FIF5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PPM-type phosphatase-like domain | 101 - 409 | IPR001932 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.16 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cis-Golgi network membrane | The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| myosin phosphatase activity | Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate. |
| protein serine/threonine phosphatase activity | Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| chloroplast organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast. |
| leaf senescence | The last stage of leaf development during which programmed degradation of macromolecules and nutrient recycling take place. |
| negative regulation of abscisic acid-activated signaling pathway | Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling. |
| peptidyl-threonine dephosphorylation | The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine. |
| response to abscisic acid | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. |
| response to water deprivation | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. |
| stomatal movement | The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata). |
35 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A5PJZ2 | PPM1L | Protein phosphatase 1L | Bos taurus (Bovine) | PR |
| P49593 | PPM1F | Protein phosphatase 1F | Homo sapiens (Human) | PR |
| Q5SGD2 | PPM1L | Protein phosphatase 1L | Homo sapiens (Human) | PR |
| O15297 | PPM1D | Protein phosphatase 1D | Homo sapiens (Human) | PR |
| Q8N819 | PPM1N | Probable protein phosphatase 1N | Homo sapiens (Human) | PR |
| Q8CGA0 | Ppm1f | Protein phosphatase 1F | Mus musculus (Mouse) | PR |
| Q8BHN0 | Ppm1l | Protein phosphatase 1L | Mus musculus (Mouse) | PR |
| Q80TL0 | Ppm1e | Protein phosphatase 1E | Mus musculus (Mouse) | PR |
| Q5JKN1 | Os01g0552300 | Probable protein phosphatase 2C 5 | Oryza sativa subsp japonica (Rice) | PR |
| Q0JLP9 | PP2C06 | Probable protein phosphatase 2C 6 | Oryza sativa subsp japonica (Rice) | PR |
| Q5SN75 | Os01g0656200 | Probable protein phosphatase 2C 8 | Oryza sativa subsp japonica (Rice) | PR |
| Q6K5I0 | Os02g0600000 | Probable protein phosphatase 2C 20 | Oryza sativa subsp japonica (Rice) | PR |
| Q7XW27 | Os04g0321800 | Probable protein phosphatase 2C 38 | Oryza sativa subsp japonica (Rice) | PR |
| Q6L482 | Os05g0358500 | Probable protein phosphatase 2C 48 | Oryza sativa subsp japonica (Rice) | PR |
| Q6L4R7 | PP2C53 | Protein phosphatase 2C 53 | Oryza sativa subsp japonica (Rice) | PR |
| Q6ZKL8 | Os08g0500300 | Probable protein phosphatase 2C 66 | Oryza sativa subsp japonica (Rice) | PR |
| Q9LMT1 | At1g18030 | Probable protein phosphatase 2C 8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81716 | PPC4-2 | Probable protein phosphatase 2C 21 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LDA7 | At3g15260 | Probable protein phosphatase 2C 39 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3EAZ3 | At3g27140 | Putative protein phosphatase 2C-like protein 45 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SD02 | At3g51470 | Probable protein phosphatase 2C 47 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P49599 | PPH1 | Protein phosphatase 2C 57 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94AT1 | At5g53140 | Probable protein phosphatase 2C 76 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GY60 | At4g03415 | Probable protein phosphatase 2C 52 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VZN9 | At1g43900 | Probable protein phosphatase 2C 11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FG61 | At5g36250 | Probable protein phosphatase 2C 74 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LNP9 | HAB2 | Protein phosphatase 2C 7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LHJ9 | PP2C38 | Probable protein phosphatase 2C 38 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94CL8 | PP2C6 | Probable protein phosphatase 2C 48 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81760 | PP2C63 | Probable protein phosphatase 2C 63 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q501F9 | PP2C67 | Probable protein phosphatase 2C 67 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O04719 | ABI2 | Protein phosphatase 2C 77 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9CAJ0 | HAB1 | Protein phosphatase 2C 16 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LRZ4 | At3g16800 | Probable protein phosphatase 2C 41 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q84JD5 | PP2C68 | Probable protein phosphatase 2C 68 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEICYENET | MMIETTATVV | KKATTTTRRR | ERSSSQAARR | RRMEIRRFKF | VSGEQEPVFV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DGDLQRRRRR | ESTVAASTST | VFYETAKEVV | VLCESLSSTV | VALPDPEAYP | KYGVASVCGR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RREMEDAVAV | HPFFSRHQTE | YSSTGFHYCG | VYDGHGCSHV | AMKCRERLHE | LVREEFEADA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DWEKSMARSF | TRMDMEVVAL | NADGAAKCRC | ELQRPDCDAV | GSTAVVSVLT | PEKIIVANCG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DSRAVLCRNG | KAIALSSDHK | PDRPDELDRI | QAAGGRVIYW | DGPRVLGVLA | MSRAIGDNYL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KPYVISRPEV | TVTDRANGDD | FLILASDGLW | DVVSNETACS | VVRMCLRGKV | NGQVSSSPER |
| 370 | 380 | 390 | 400 | 410 | |
| EMTGVGAGNV | VVGGGDLPDK | ACEEASLLLT | RLALARQSSD | NVSVVVVDLR | RDT |