Q9LNP9

PR
Gene name
HAB2 (At1g17550, F1L3.32)
Protein name
Protein phosphatase 2C 7
Names
AtPP2C07, Protein HYPERSENSITIVE TO ABA 2, Protein phosphatase 2C HAB2, PP2C HAB2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G17550
EC number
3.1.3.16: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-257 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LNP9

Entry ID Method Resolution Chain Position Source
AF-Q9LNP9-F1 Predicted AlphaFoldDB

20 variants for Q9LNP9

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH04592682 5 S>L No 1000Genomes
tmp_1_6034990_C_A 25 S>Y No 1000Genomes
ENSVATH04592685 57 C>Y No 1000Genomes
ENSVATH04592686 59 M>I No 1000Genomes
ENSVATH11410760 59 M>L No 1000Genomes
ENSVATH13914841 65 E>D No 1000Genomes
ENSVATH11410761 78 F>L No 1000Genomes
ENSVATH04592687 84 E>D No 1000Genomes
ENSVATH04592688 89 E>G No 1000Genomes
ENSVATH11410762 93 S>T No 1000Genomes
tmp_1_6035214_G_A 100 E>K No 1000Genomes
tmp_1_6035323_T_C 136 I>T No 1000Genomes
tmp_1_6035403_G_A 163 V>I No 1000Genomes
tmp_1_6035443_G_A 176 G>E No 1000Genomes
tmp_1_6035865_G_A 251 D>N No 1000Genomes
tmp_1_6035997_A_G 295 K>E No 1000Genomes
tmp_1_6036033_C_A 307 P>T No 1000Genomes
ENSVATH11410764 316 V>I No 1000Genomes
ENSVATH11410875 349 A>V No 1000Genomes
ENSVATH04592692 416 T>M No 1000Genomes

No associated diseases with Q9LNP9

2 regional properties for Q9LNP9

Type Name Position InterPro Accession
binding_site PPM-type phosphatase, divalent cation binding 237 - 245 IPR000222
domain PPM-type phosphatase-like domain 178 - 501 IPR001932

Functions

Description
EC Number 3.1.3.16 Phosphoric monoester hydrolases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
myosin phosphatase activity Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.
protein serine/threonine phosphatase activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.

2 GO annotations of biological process

Name Definition
abscisic acid-activated signaling pathway The series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
peptidyl-threonine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.

35 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A5PJZ2 PPM1L Protein phosphatase 1L Bos taurus (Bovine) PR
P49593 PPM1F Protein phosphatase 1F Homo sapiens (Human) PR
Q5SGD2 PPM1L Protein phosphatase 1L Homo sapiens (Human) PR
O15297 PPM1D Protein phosphatase 1D Homo sapiens (Human) PR
Q8N819 PPM1N Probable protein phosphatase 1N Homo sapiens (Human) PR
Q8CGA0 Ppm1f Protein phosphatase 1F Mus musculus (Mouse) PR
Q8BHN0 Ppm1l Protein phosphatase 1L Mus musculus (Mouse) PR
Q80TL0 Ppm1e Protein phosphatase 1E Mus musculus (Mouse) PR
Q5JKN1 Os01g0552300 Probable protein phosphatase 2C 5 Oryza sativa subsp japonica (Rice) PR
Q5SN75 Os01g0656200 Probable protein phosphatase 2C 8 Oryza sativa subsp japonica (Rice) PR
Q6K5I0 Os02g0600000 Probable protein phosphatase 2C 20 Oryza sativa subsp japonica (Rice) PR
Q7XW27 Os04g0321800 Probable protein phosphatase 2C 38 Oryza sativa subsp japonica (Rice) PR
Q6L482 Os05g0358500 Probable protein phosphatase 2C 48 Oryza sativa subsp japonica (Rice) PR
Q6ZKL8 Os08g0500300 Probable protein phosphatase 2C 66 Oryza sativa subsp japonica (Rice) PR
Q6L4R7 PP2C53 Protein phosphatase 2C 53 Oryza sativa subsp japonica (Rice) PR
Q0JLP9 PP2C06 Probable protein phosphatase 2C 6 Oryza sativa subsp japonica (Rice) PR
Q9LMT1 At1g18030 Probable protein phosphatase 2C 8 Arabidopsis thaliana (Mouse-ear cress) PR
O81716 PPC4-2 Probable protein phosphatase 2C 21 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LDA7 At3g15260 Probable protein phosphatase 2C 39 Arabidopsis thaliana (Mouse-ear cress) PR
Q3EAZ3 At3g27140 Putative protein phosphatase 2C-like protein 45 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SD02 At3g51470 Probable protein phosphatase 2C 47 Arabidopsis thaliana (Mouse-ear cress) PR
P49599 PPH1 Protein phosphatase 2C 57 Arabidopsis thaliana (Mouse-ear cress) PR
Q94AT1 At5g53140 Probable protein phosphatase 2C 76 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GY60 At4g03415 Probable protein phosphatase 2C 52 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VZN9 At1g43900 Probable protein phosphatase 2C 11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FG61 At5g36250 Probable protein phosphatase 2C 74 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FIF5 SAG113 Probable protein phosphatase 2C 78 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LHJ9 PP2C38 Probable protein phosphatase 2C 38 Arabidopsis thaliana (Mouse-ear cress) PR
Q94CL8 PP2C6 Probable protein phosphatase 2C 48 Arabidopsis thaliana (Mouse-ear cress) PR
O81760 PP2C63 Probable protein phosphatase 2C 63 Arabidopsis thaliana (Mouse-ear cress) PR
Q501F9 PP2C67 Probable protein phosphatase 2C 67 Arabidopsis thaliana (Mouse-ear cress) PR
O04719 ABI2 Protein phosphatase 2C 77 Arabidopsis thaliana (Mouse-ear cress) PR
Q9CAJ0 HAB1 Protein phosphatase 2C 16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRZ4 At3g16800 Probable protein phosphatase 2C 41 Arabidopsis thaliana (Mouse-ear cress) PR
Q84JD5 PP2C68 Probable protein phosphatase 2C 68 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEEISPAVAL TLGLANTMCD SGISSTFDIS ELENVTDAAD MLCNQKRQRY SNGVVDCIMG
70 80 90 100 110 120
SVSEEKTLSE VRSLSSDFSV TVQESEEDEP LVSDATIISE GLIVVDARSE ISLPDTVETD
130 140 150 160 170 180
NGRVLATAII LNETTIEQVP TAEVLIASLN HDVNMEVATS EVVIRLPEEN PNVARGSRSV
190 200 210 220 230 240
YELECIPLWG TISICGGRSE MEDAVRALPH FLKIPIKMLM GDHEGMSPSL PYLTSHFFGV
250 260 270 280 290 300
YDGHGGAQVA DYCHDRIHSA LAEEIERIKE ELCRRNTGEG RQVQWEKVFV DCYLKVDDEV
310 320 330 340 350 360
KGKINRPVVG SSDRMVLEAV SPETVGSTAV VALVCSSHII VSNCGDSRAV LLRGKDSMPL
370 380 390 400 410 420
SVDHKPDRED EYARIEKAGG KVIQWQGARV SGVLAMSRSI GDQYLEPFVI PDPEVTFMPR
430 440 450 460 470 480
AREDECLILA SDGLWDVMSN QEACDFARRR ILAWHKKNGA LPLAERGVGE DQACQAAAEY
490 500 510
LSKLAIQMGS KDNISIIVID LKAQRKFKTR S