Q9LMT1

PR
Gene name
At1g18030 (T10F20.4)
Protein name
Probable protein phosphatase 2C 8
Names
AtPP2C08
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G18030
EC number
3.1.3.16: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-98 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LMT1

Entry ID Method Resolution Chain Position Source
AF-Q9LMT1-F1 Predicted AlphaFoldDB

22 variants for Q9LMT1

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH11440291 11 M>T No 1000Genomes
tmp_1_6204494_T_C 32 V>A No 1000Genomes
ENSVATH11440292 37 K>T No 1000Genomes
ENSVATH13917485 46 E>K No 1000Genomes
tmp_1_6204584_G_T 62 S>I No 1000Genomes
ENSVATH13917488 62 S>R No 1000Genomes
ENSVATH11440293 64 V>L No 1000Genomes
tmp_1_6204609_G_C 70 E>D No 1000Genomes
ENSVATH04594893 111 A>S No 1000Genomes
tmp_1_6204968_G_T 137 G>W No 1000Genomes
tmp_1_6205120_G_C 154 E>Q No 1000Genomes
tmp_1_6205236_G_T 157 R>L No 1000Genomes
tmp_1_6205260_A_G 165 Q>R No 1000Genomes
ENSVATH11440336 166 K>E No 1000Genomes
ENSVATH11440337 174 D>A No 1000Genomes
tmp_1_6205645_G_A 202 R>Q No 1000Genomes
tmp_1_6205667_G_T 209 L>F No 1000Genomes
ENSVATH04594900 219 L>F No 1000Genomes
ENSVATH11440340 249 N>D No 1000Genomes
ENSVATH04594905 320 V>I No 1000Genomes
ENSVATH04594906 326 R>C No 1000Genomes
ENSVATH13917490 347 V>D No 1000Genomes

No associated diseases with Q9LMT1

1 regional properties for Q9LMT1

Type Name Position InterPro Accession
domain PPM-type phosphatase-like domain 64 - 348 IPR001932

Functions

Description
EC Number 3.1.3.16 Phosphoric monoester hydrolases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
myosin phosphatase activity Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.

1 GO annotations of biological process

Name Definition
protein dephosphorylation The process of removing one or more phosphoric residues from a protein.

29 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A5PJZ2 PPM1L Protein phosphatase 1L Bos taurus (Bovine) PR
P49593 PPM1F Protein phosphatase 1F Homo sapiens (Human) PR
O15297 PPM1D Protein phosphatase 1D Homo sapiens (Human) PR
Q5SGD2 PPM1L Protein phosphatase 1L Homo sapiens (Human) PR
Q8CGA0 Ppm1f Protein phosphatase 1F Mus musculus (Mouse) PR
Q80TL0 Ppm1e Protein phosphatase 1E Mus musculus (Mouse) PR
Q8BHN0 Ppm1l Protein phosphatase 1L Mus musculus (Mouse) PR
Q5JKN1 Os01g0552300 Probable protein phosphatase 2C 5 Oryza sativa subsp japonica (Rice) PR
Q0JLP9 PP2C06 Probable protein phosphatase 2C 6 Oryza sativa subsp japonica (Rice) PR
Q5SN75 Os01g0656200 Probable protein phosphatase 2C 8 Oryza sativa subsp japonica (Rice) PR
Q6K5I0 Os02g0600000 Probable protein phosphatase 2C 20 Oryza sativa subsp japonica (Rice) PR
Q7XW27 Os04g0321800 Probable protein phosphatase 2C 38 Oryza sativa subsp japonica (Rice) PR
Q6L482 Os05g0358500 Probable protein phosphatase 2C 48 Oryza sativa subsp japonica (Rice) PR
Q6L4R7 PP2C53 Protein phosphatase 2C 53 Oryza sativa subsp japonica (Rice) PR
Q6ZKL8 Os08g0500300 Probable protein phosphatase 2C 66 Oryza sativa subsp japonica (Rice) PR
Q9LNP9 HAB2 Protein phosphatase 2C 7 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VZN9 At1g43900 Probable protein phosphatase 2C 11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9CAJ0 HAB1 Protein phosphatase 2C 16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRZ4 At3g16800 Probable protein phosphatase 2C 41 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GY60 At4g03415 Probable protein phosphatase 2C 52 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FG61 At5g36250 Probable protein phosphatase 2C 74 Arabidopsis thaliana (Mouse-ear cress) PR
O04719 ABI2 Protein phosphatase 2C 77 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FIF5 SAG113 Probable protein phosphatase 2C 78 Arabidopsis thaliana (Mouse-ear cress) PR
O81716 PPC4-2 Probable protein phosphatase 2C 21 Arabidopsis thaliana (Mouse-ear cress) PR
P49599 PPH1 Protein phosphatase 2C 57 Arabidopsis thaliana (Mouse-ear cress) PR
Q3EAZ3 At3g27140 Putative protein phosphatase 2C-like protein 45 Arabidopsis thaliana (Mouse-ear cress) PR
Q94AT1 At5g53140 Probable protein phosphatase 2C 76 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LDA7 At3g15260 Probable protein phosphatase 2C 39 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SD02 At3g51470 Probable protein phosphatase 2C 47 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MLEKESDLTA MEKPNNKHAA DSFSSEDLVS PVKKAKKSEE VSGGGEAVAA VGNREAEEDK
70 80 90 100 110 120
PSFVSEEKKE FLVEADVAED KGARHTMEDV WVVLPDASLD FPGTLRCAHF AIYDGHGGRL
130 140 150 160 170 180
AAEFAKKHLH LNVLSAGLPR ELLDVKVAKK AILEGFRKTD ELLLQKSVSG GWQDGATAVC
190 200 210 220 230 240
VWILDQKVFV ANIGDAKAVL ARSSTTNELG NHTEAGNPLK AIVLTREHKA IYPQERSRIQ
250 260 270 280 290 300
KSGGVISSNG RLQGRLEVSR AFGDRHFKKF GVSATPDIHA FELTERENFM ILGCDGLWEV
310 320 330 340 350
FGPSDAVGFV QKLLKEGLHV STVSRRLVKE AVKERRCKDN CTAIVIVFKR V