Q84JD5

PR
Gene name
PP2C68
Protein name
Probable protein phosphatase 2C 68
Names
AtPP2C68
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G06750
EC number
3.1.3.16: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-70 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q84JD5

Entry ID Method Resolution Chain Position Source
AF-Q84JD5-F1 Predicted AlphaFoldDB

17 variants for Q84JD5

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_2088236_A_G 4 W>R No 1000Genomes
tmp_5_2088222_C_T 8 M>I No 1000Genomes
tmp_5_2088218_G_A 10 L>F No 1000Genomes
tmp_5_2087999_C_T,A 83 V>F No 1000Genomes
tmp_5_2087999_C_T,A 83 V>I No 1000Genomes
ENSVATH06932972 87 D>N No 1000Genomes
ENSVATH10617457 115 C>Y No 1000Genomes
ENSVATH03031455 202 E>D No 1000Genomes
ENSVATH03031452 245 R>C No 1000Genomes
ENSVATH03031451 246 P>S No 1000Genomes
ENSVATH03031450 260 A>P No 1000Genomes
tmp_5_2086885_G_C 264 Q>E No 1000Genomes
tmp_5_2086876_C_T 267 V>I No 1000Genomes
tmp_5_2086864_C_T 271 E>K No 1000Genomes
ENSVATH00609397 321 R>K No 1000Genomes
ENSVATH10617433 339 K>R No 1000Genomes
ENSVATH06932963 341 E>A No 1000Genomes

No associated diseases with Q84JD5

2 regional properties for Q84JD5

Type Name Position InterPro Accession
binding_site PPM-type phosphatase, divalent cation binding 82 - 90 IPR000222
domain PPM-type phosphatase-like domain 36 - 359 IPR001932

Functions

Description
EC Number 3.1.3.16 Phosphoric monoester hydrolases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
myosin phosphatase activity Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.
protein serine/threonine phosphatase activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.

1 GO annotations of biological process

Name Definition
peptidyl-threonine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.

18 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O15297 PPM1D Protein phosphatase 1D Homo sapiens (Human) PR
Q8N819 PPM1N Probable protein phosphatase 1N Homo sapiens (Human) PR
Q10NB9 Os03g0275100 Probable protein phosphatase 2C 31 Oryza sativa subsp japonica (Rice) PR
Q7XHN8 Os07g0114000 Probable protein phosphatase 2C 61 Oryza sativa subsp japonica (Rice) PR
Q2QN36 Os12g0580900 Probable protein phosphatase 2C 78 Oryza sativa subsp japonica (Rice) PR
Q6ZHC8 Os02g0685600 Probable protein phosphatase 2C 25 Oryza sativa subsp japonica (Rice) PR
O81760 PP2C63 Probable protein phosphatase 2C 63 Arabidopsis thaliana (Mouse-ear cress) PR
Q501F9 PP2C67 Probable protein phosphatase 2C 67 Arabidopsis thaliana (Mouse-ear cress) PR
Q94CL8 PP2C6 Probable protein phosphatase 2C 48 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LHJ9 PP2C38 Probable protein phosphatase 2C 38 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LNP9 HAB2 Protein phosphatase 2C 7 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VZN9 At1g43900 Probable protein phosphatase 2C 11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9CAJ0 HAB1 Protein phosphatase 2C 16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRZ4 At3g16800 Probable protein phosphatase 2C 41 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GY60 At4g03415 Probable protein phosphatase 2C 52 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FG61 At5g36250 Probable protein phosphatase 2C 74 Arabidopsis thaliana (Mouse-ear cress) PR
O04719 ABI2 Protein phosphatase 2C 77 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FIF5 SAG113 Probable protein phosphatase 2C 78 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MFSWLARMAL FCLRPMRRYG RMNRDDDDDD DHDGDSSSSG DSLLWSRELE RHSFGDFSIA
70 80 90 100 110 120
VVQANEVIED HSQVETGNGA VFVGVYDGHG GPEASRYISD HLFSHLMRVS RERSCISEEA
130 140 150 160 170 180
LRAAFSATEE GFLTLVRRTC GLKPLIAAVG SCCLVGVIWK GTLLIANVGD SRAVLGSMGS
190 200 210 220 230 240
NNNRSNKIVA EQLTSDHNAA LEEVRQELRS LHPDDSHIVV LKHGVWRIKG IIQVSRSIGD
250 260 270 280 290 300
AYLKRPEFSL DPSFPRFHLA EELQRPVLSA EPCVYTRVLQ TSDKFVIFAS DGLWEQMTNQ
310 320 330 340 350 360
QAVEIVNKHP RPGIARRLVR RAITIAAKKR EMNYDDLKKV ERGVRRFFHD DITVVVIFID
370 380 390
NELLMVEKAT VPELSIKGFS HTVGPSKFSI FLS