Q94CL8
Gene name |
PP2C6 |
Protein name |
Probable protein phosphatase 2C 48 |
Names |
AtPP2C48, Protein phosphatase 2C 6 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G55050 |
EC number |
3.1.3.16: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q94CL8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q94CL8-F1 | Predicted | AlphaFoldDB |
17 variants for Q94CL8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_20401847_C_T | 26 | G>S | No | 1000Genomes | |
| tmp_3_20401834_G_A | 30 | T>M | No | 1000Genomes | |
| ENSVATH00420090 | 38 | L>V | No | 1000Genomes | |
| ENSVATH12767013 | 85 | V>I | No | 1000Genomes | |
| tmp_3_20401617_A_C | 102 | D>E | No | 1000Genomes | |
| tmp_3_20401580_G_T | 115 | Q>K | No | 1000Genomes | |
| ENSVATH06317509 | 125 | R>K | No | 1000Genomes | |
| ENSVATH02506538 | 147 | Q>K | No | 1000Genomes | |
| ENSVATH00420089 | 167 | V>D | No | 1000Genomes | |
| tmp_3_20401375_G_A | 183 | P>L | No | 1000Genomes | |
| tmp_3_20401365_C_A | 186 | E>D | No | 1000Genomes | |
| ENSVATH06317507 | 297 | S>G | No | 1000Genomes | |
| ENSVATH06317504 | 326 | A>S | No | 1000Genomes | |
| tmp_3_20400809_T_C | 339 | I>V | No | 1000Genomes | |
| ENSVATH06317503 | 359 | H>N | No | 1000Genomes | |
| ENSVATH00420087 | 382 | P>A | No | 1000Genomes | |
| tmp_3_20400677_C_T | 383 | V>I | No | 1000Genomes |
No associated diseases with Q94CL8
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.16 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| myosin phosphatase activity | Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate. |
| protein serine/threonine phosphatase activity | Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| peptidyl-threonine dephosphorylation | The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine. |
18 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O15297 | PPM1D | Protein phosphatase 1D | Homo sapiens (Human) | PR |
| Q8N819 | PPM1N | Probable protein phosphatase 1N | Homo sapiens (Human) | PR |
| Q6ZHC8 | Os02g0685600 | Probable protein phosphatase 2C 25 | Oryza sativa subsp japonica (Rice) | PR |
| Q10NB9 | Os03g0275100 | Probable protein phosphatase 2C 31 | Oryza sativa subsp japonica (Rice) | PR |
| Q7XHN8 | Os07g0114000 | Probable protein phosphatase 2C 61 | Oryza sativa subsp japonica (Rice) | PR |
| Q2QN36 | Os12g0580900 | Probable protein phosphatase 2C 78 | Oryza sativa subsp japonica (Rice) | PR |
| O81760 | PP2C63 | Probable protein phosphatase 2C 63 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q501F9 | PP2C67 | Probable protein phosphatase 2C 67 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LHJ9 | PP2C38 | Probable protein phosphatase 2C 38 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LNP9 | HAB2 | Protein phosphatase 2C 7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VZN9 | At1g43900 | Probable protein phosphatase 2C 11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GY60 | At4g03415 | Probable protein phosphatase 2C 52 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FG61 | At5g36250 | Probable protein phosphatase 2C 74 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FIF5 | SAG113 | Probable protein phosphatase 2C 78 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O04719 | ABI2 | Protein phosphatase 2C 77 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q84JD5 | PP2C68 | Probable protein phosphatase 2C 68 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9CAJ0 | HAB1 | Protein phosphatase 2C 16 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LRZ4 | At3g16800 | Probable protein phosphatase 2C 41 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVSTTFRRIV | SPCWRPFGIG | EDSSPGSDDT | NGRLDGLLWY | KDSGNHITGE | FSMAVVQANN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLEDHSQLES | GPISLHESGP | EATFVGVYDG | HGGPEAARFV | NDRLFYNIKR | YTSEQRGMSP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DVITRGFVAT | EEEFLGLVQE | QWKTKPQIAS | VGACCLVGIV | CNGLLYVANA | GDSRVVLGKV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ANPFKELKAV | QLSTEHNASI | ESVREELRLL | HPDDPNIVVL | KHKVWRVKGI | IQVSRSIGDA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YLKRAEFNQE | PLLPKFRVPE | RFEKPIMRAE | PTITVHKIHP | EDQFLIFASD | GLWEHLSNQE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AVDIVNSCPR | NGVARKLVKA | ALQEAAKKRE | MRYSDLEKIE | RGIRRHFHDD | ITVIVVFLHA |
| 370 | 380 | ||||
| TNFATRTPIS | VKGGGLLSAH | NPVL |