Q9LUC6

PR
Gene name
CYP72A14 (At3g14680, MIE1.18)
Protein name
Cytochrome P450 72A14
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G14680
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

38-117 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LUC6

Entry ID Method Resolution Chain Position Source
AF-Q9LUC6-F1 Predicted AlphaFoldDB

36 variants for Q9LUC6

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_4934486_A_G 3 I>M No 1000Genomes
tmp_3_4934515_C_T 13 A>V No 1000Genomes
tmp_3_4934590_C_T 38 S>F No 1000Genomes
tmp_3_4934604_G_T 43 G>C No 1000Genomes
tmp_3_4934611_C_T 45 S>F No 1000Genomes
ENSVATH05831908 47 T>S No 1000Genomes
ENSVATH05831910 64 I>L No 1000Genomes
ENSVATH05831911 84 H>Y No 1000Genomes
ENSVATH13919922 102 P>L No 1000Genomes
tmp_3_4934919_T_C 109 M>T No 1000Genomes
ENSVATH00323609 125 Q>K No 1000Genomes
tmp_3_4935074_C_A 161 L>I No 1000Genomes
ENSVATH05831915 169 H>Y No 1000Genomes
ENSVATH05831916 177 E>K No 1000Genomes
ENSVATH00323610 185 L>S No 1000Genomes
tmp_3_4935280_G_A 196 D>N No 1000Genomes
tmp_3_4935344_G_A 217 S>N No 1000Genomes
ENSVATH05831917 223 R>G No 1000Genomes
tmp_3_4935424_A_T 244 I>F No 1000Genomes
ENSVATH02145787 249 Y>N No 1000Genomes
tmp_3_4935599_A_T 257 R>W No 1000Genomes
ENSVATH00323612 284 E>D No 1000Genomes
ENSVATH00323613 288 E>D No 1000Genomes
tmp_3_4935707_A_G 293 I>V No 1000Genomes
ENSVATH10681195 312 M>I No 1000Genomes
tmp_3_4935876_G_A 349 R>Q No 1000Genomes
tmp_3_4935908_C_G 360 Q>E No 1000Genomes
ENSVATH02145789 375 I>V No 1000Genomes
tmp_3_4936052_T_A 377 Y>N No 1000Genomes
ENSVATH05831923 394 H>R No 1000Genomes
ENSVATH05831924 400 G>R No 1000Genomes
tmp_3_4936179_G_A 419 R>H No 1000Genomes
tmp_3_4936359_A_G 479 Q>R No 1000Genomes
tmp_3_4936362_G_A 480 R>K No 1000Genomes
ENSVATH13919924 484 E>Q No 1000Genomes
ENSVATH02145791 488 S>T No 1000Genomes

No associated diseases with Q9LUC6

No regional properties for Q9LUC6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9LUC6

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

45 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P79102 CYP3A28 Cytochrome P450 3A28 Bos taurus (Bovine) PR
Q9VYQ5 Cyp318a1 Probable cytochrome P450 318a1 Drosophila melanogaster (Fruit fly) PR
Q9V776 Cyp317a1 Probable cytochrome P450 317a1 Drosophila melanogaster (Fruit fly) PR
Q9V7G5 Cyp4aa1 Probable cytochrome P450 4aa1 Drosophila melanogaster (Fruit fly) PR
Q9VG82 Cyp9f2 Probable cytochrome P450 9f2 Drosophila melanogaster (Fruit fly) PR
Q9V559 Cyp4p3 Probable cytochrome P450 4p3 Drosophila melanogaster (Fruit fly) PR
Q9VMS7 Cyp4ac3 Probable cytochrome P450 4ac3 Drosophila melanogaster (Fruit fly) PR
Q9VMS8 Cyp4ac2 Probable cytochrome P450 4ac2 Drosophila melanogaster (Fruit fly) PR
Q9VVN6 Cyp312a1 Probable cytochrome P450 312a1 Drosophila melanogaster (Fruit fly) PR
Q9VXY0 Cyp4s3 Probable cytochrome P450 4s3 Drosophila melanogaster (Fruit fly) PR
Q9V4U9 Cyp6a13 Probable cytochrome P450 6a13 Drosophila melanogaster (Fruit fly) PR
Q9V773 Cyp6a20 Probable cytochrome P450 6a20 Drosophila melanogaster (Fruit fly) PR
Q9V4U7 Cyp6a14 Probable cytochrome P450 6a14 Drosophila melanogaster (Fruit fly) PR
P13584 CYP4B1 Cytochrome P450 4B1 Homo sapiens (Human) PR
Q02928 CYP4A11 Cytochrome P450 4A11 Homo sapiens (Human) PR
Q5TCH4 CYP4A22 Cytochrome P450 4A22 Homo sapiens (Human) PR
Q6ZWL3 CYP4V2 Cytochrome P450 4V2 Homo sapiens (Human) PR
Q86W10 CYP4Z1 Cytochrome P450 4Z1 Homo sapiens (Human) PR
Q8N1L4 CYP4Z2P Putative inactive cytochrome P450 family member 4Z2 Homo sapiens (Human) PR
B6SSW8 CYP714B3 Cytochrome P450 714B3 Zea mays (Maize) PR
O35728 Cyp4a14 Cytochrome P450 4A14 Mus musculus (Mouse) PR
Q91WL5 Cyp4a12a Cytochrome P450 4A12A Mus musculus (Mouse) PR
Q8SPK1 CYP4A24 Cytochrome P450 4A24 Sus scrofa (Pig) PR
Q9GJX5 CYP4A21 Taurochenodeoxycholic 6 alpha-hydroxylase Sus scrofa (Pig) PR
Q8SPK0 CYP4A25 Cytochrome P450 4A25 Sus scrofa (Pig) PR
G3V7X8 Cyp26b1 Cytochrome P450 26B1 Rattus norvegicus (Rat) PR
P20816 Cyp4a2 Cytochrome P450 4A2 Rattus norvegicus (Rat) PR
P24464 Cyp4a12 Cytochrome P450 4A12 Rattus norvegicus (Rat) PR
P20817 Cyp4a14 Cytochrome P450 4A14 Rattus norvegicus (Rat) PR
Q05JG2 CYP707A5 Abscisic acid 8'-hydroxylase 1 Oryza sativa subsp japonica (Rice) PR
Q0DS59 CYP714B2 Cytochrome P450 714B2 Oryza sativa subsp japonica (Rice) PR
Q6F4F5 CYP724B1 Cytochrome P450 724B1 Oryza sativa subsp japonica (Rice) PR
Q5KQH7 CYP714D1 Cytochrome P450 714D1 Oryza sativa subsp japonica (Rice) PR
Q9C788 CYP704B1 Cytochrome P450 704B1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZUX1 CYP94C1 Cytochrome P450 94C1 Arabidopsis thaliana (Mouse-ear cress) PR
O81077 CYP707A2 Abscisic acid 8'-hydroxylase 2 Arabidopsis thaliana (Mouse-ear cress) PR
O64698 CYP710A2 Cytochrome P450 710A2 Arabidopsis thaliana (Mouse-ear cress) PR
O64697 CYP710A1 Cytochrome P450 710A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q94IA6 CYP90D1 3-epi-6-deoxocathasterone 23-monooxygenase CYP90D1 Arabidopsis thaliana (Mouse-ear cress) PR
Q6TBX7 CYP97C1 Carotene epsilon-monooxygenase, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC5 CYP72A15 Cytochrome P450 72A15 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC8 CYP72A13 Cytochrome P450 72A13 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC9 CYP72A11 Cytochrome P450 72A11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SHG5 CYP72C1 Cytochrome P450 72C1 Arabidopsis thaliana (Mouse-ear cress) PR
Q6EIG3 cyp26b1 Cytochrome P450 26B1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MEISVSSVTF SLAVVVVSWW VWRTLKWVWF TPKMLERSLR RQGLSGTSYT PLIGDFKKMI
70 80 90 100 110 120
SMFIEATSKP IKPTDDITPR VMPHPLQMLK THGRTNLTWF GPIPTITIMD PEQIKEVFNK
130 140 150 160 170 180
VYDFQKAHTF PLSKILGTGL VSYDGDKWAQ HRRIINPAFH LEKIKNMVHV FHESCSELVG
190 200 210 220 230 240
EWDKLVSDKG SSCEVDVWPG LTSMTADVIS RTAFGSSYRE GHRIFELQAE LAQLVMQAFQ
250 260 270 280 290 300
KFFIPGYIYL PTKGNRRMKT AAREIQDILR GIINKRERAR ESGEAPSEDL LGILLESNLG
310 320 330 340 350 360
QTEGNGMSTE DMMEECKLFY LAGQETTSVL LVWTMVLLSQ HQDWQARARE EVKQVFGDKQ
370 380 390 400 410 420
PDTEGLNQLK VMTMILYEVL RLYPPVVQLT RAIHKEMKLG DLTLPGGVQI SLPVLLVHRD
430 440 450 460 470 480
TELWGNDAGE FKPERFKDGL SKATKNQVSF FPFAWGPRIC IGQNFTLLEA KMAMSLILQR
490 500 510
FSFELSPSYV HAPYTIITLY PQFGAHLMLH KL