Q02928
PR
Gene name |
CYP4A11 |
Protein name |
Cytochrome P450 4A11 |
Names |
20-hydroxyeicosatetraenoic acid synthase, 20-HETE synthase, CYP4AII, CYPIVA11, Cytochrome P-450HK-omega, Cytochrome P450HL-omega, Fatty acid omega-hydroxylase, Lauric acid omega-hydroxylase, Long-chain fatty acid omega-monooxygenase |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:1579 |
EC number |
1.14.14.1: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q02928
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q02928-F1 | Predicted | AlphaFoldDB |
542 variants for Q02928
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA340228780 rs1391952983 |
2 | S>N | No |
ClinGen TOPMed |
|
|
rs1225641495 CA340228773 |
2 | S>R | No |
ClinGen Ensembl |
|
|
rs772300381 CA839852 |
3 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1557564122 CA340228770 COSM1202880 |
3 | V>I | large_intestine [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
rs1284603244 CA340228738 |
6 | L>P | No |
ClinGen gnomAD |
|
|
CA340228726 rs1407461140 |
7 | S>I | No |
ClinGen gnomAD |
|
|
rs1350346326 CA340228724 |
7 | S>R | No |
ClinGen TOPMed gnomAD |
|
|
rs557358158 CA839850 |
8 | P>H | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs557358158 CA839849 |
8 | P>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA839848 rs749291376 |
9 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs1400486144 CA340228688 |
11 | L>I | No |
ClinGen TOPMed gnomAD |
|
|
CA839847 rs779900245 |
11 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1431721030 CA340228675 |
12 | L>P | No |
ClinGen gnomAD |
|
|
CA340228665 rs1284674948 |
13 | G>V | No |
ClinGen TOPMed |
|
|
rs1472299941 CA340228655 |
14 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1156955746 CA340228659 |
14 | D>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA839845 rs545726650 |
15 | V>A | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs756981683 CA839843 |
18 | I>L | No |
ClinGen ExAC TOPMed |
|
|
rs143389976 CA839841 |
21 | A>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs766863924 CA839838 |
22 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839839 rs201643223 |
22 | A>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA340228525 rs1426065355 |
28 | L>F | No |
ClinGen TOPMed |
|
|
CA839836 rs750842065 |
28 | L>H | No |
ClinGen ExAC |
|
| TCGA novel | 29 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs149204978 CA839833 |
35 | V>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA839834 rs762154121 |
35 | V>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340228464 rs762154121 |
35 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340228445 rs1557563781 |
37 | L>I | No |
ClinGen Ensembl |
|
|
rs1469688659 CA340228439 |
37 | L>P | No |
ClinGen gnomAD |
|
|
CA839832 rs771237083 |
38 | Y>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775436920 CA839830 |
40 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs745767999 CA839828 |
41 | R>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA839827 rs781095828 |
42 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA839826 rs770625688 |
42 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 43 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA21999675 rs868630045 |
46 | K>R | No |
ClinGen Ensembl |
|
|
rs1206414104 CA340228278 |
49 | Q>* | No |
ClinGen gnomAD |
|
|
CA340228252 rs1173331126 |
50 | Q>L | No |
ClinGen TOPMed |
|
|
CA340228228 rs1216586800 |
51 | F>L | No |
ClinGen TOPMed |
|
|
rs758007868 CA839823 |
52 | P>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 53 | C>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA340228181 rs778258571 |
54 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs536828497 CA839819 |
54 | P>H | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA839820 rs536828497 |
54 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs778258571 CA839821 |
54 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA839818 rs375391044 |
55 | P>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA21999636 rs375391044 |
55 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs757551399 CA839817 |
57 | H>N | No |
ClinGen ExAC gnomAD |
|
|
rs751794931 CA839816 |
59 | L>R | No |
ClinGen ExAC gnomAD |
|
|
rs764259809 CA839815 |
60 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 61 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs370538155 CA340228082 CA21999599 |
61 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC TOPMed gnomAD NCI-TCGA |
|
rs370538155 CA839813 |
61 | G>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA340228056 rs1200488431 |
63 | I>L | No |
ClinGen TOPMed |
|
|
CA839812 rs765216120 |
64 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1488216334 CA340228036 |
64 | Q>R | No |
ClinGen TOPMed |
|
|
CA839811 rs759581767 |
65 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA839782 rs148145351 |
66 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs183136099 CA839781 |
67 | Q>* | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA21995480 rs1054435211 |
67 | Q>H | No |
ClinGen TOPMed gnomAD |
|
|
rs747499896 CA839780 |
68 | Q>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1321009 CA21995446 rs936004142 |
69 | D>E | ovary [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
rs778176247 CA839779 |
69 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
CA340227765 rs1230486421 |
70 | Q>E | No |
ClinGen TOPMed |
|
|
CA839777 rs752974511 |
71 | E>* | No |
ClinGen ExAC gnomAD |
|
|
CA21995428 rs200512624 |
71 | E>G | No |
ClinGen 1000Genomes |
|
|
rs141891892 CA21995416 |
74 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839775 rs141891892 |
74 | R>Q | Variant assessed as Somatic; 9.24e-05 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs201585437 CA839776 |
74 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA839774 rs753908188 |
75 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340227346 rs1481257981 CA340227347 |
78 | W>C | No |
ClinGen gnomAD |
|
| TCGA novel | 80 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1208465022 CA340227337 |
80 | E>G | No |
ClinGen gnomAD |
|
|
CA839773 rs145173494 |
80 | E>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs202200720 CA21995401 |
81 | T>A | No |
ClinGen 1000Genomes |
|
|
CA340227328 rs1245662620 |
81 | T>I | No |
ClinGen TOPMed |
|
|
CA839772 rs373407533 |
83 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1263971882 CA340227313 |
84 | S>G | No |
ClinGen gnomAD |
|
|
CA340227301 rs1225647908 |
85 | A>V | No |
ClinGen gnomAD |
|
|
rs146942170 CA839770 |
87 | P>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs922753951 CA21995370 |
87 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs146942170 CA340227287 |
87 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs146942170 CA839771 |
87 | P>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839769 rs752182690 |
88 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768154797 CA839767 |
89 | W>G | No |
ClinGen ExAC gnomAD |
|
|
CA839766 rs762642639 |
90 | L>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839762 rs747518415 |
93 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769288303 CA839763 |
93 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA340227205 rs747518415 |
93 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1157769715 CA340227203 |
94 | K>E | No |
ClinGen gnomAD |
|
|
rs1410816810 CA340227192 |
94 | K>N | No |
ClinGen gnomAD |
|
|
CA839761 rs778190816 |
94 | K>T | No |
ClinGen ExAC gnomAD |
|
|
CA839760 rs550471765 |
95 | V>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs550471765 CA340227183 |
95 | V>D | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA340227188 rs1278478016 |
95 | V>I | No |
ClinGen gnomAD |
|
|
COSM1202882 rs370892962 CA839759 |
96 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs779308763 CA839758 |
96 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755207747 CA839757 |
97 | V>G | No |
ClinGen ExAC |
|
|
CA340227169 rs1205779590 |
97 | V>I | No |
ClinGen gnomAD |
|
|
rs1011360462 CA21995279 |
98 | Q>R | No |
ClinGen Ensembl |
|
|
CA340227142 rs1369984550 |
99 | L>F | No |
ClinGen TOPMed |
|
|
rs754082184 CA839756 |
99 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1280460311 CA340227125 |
101 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1260181141 CA340227101 |
102 | P>L | No |
ClinGen gnomAD |
|
|
CA839755 rs780352553 |
104 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA340227082 rs1239871437 |
104 | Y>H | No |
ClinGen gnomAD |
|
|
CA839753 rs750399611 |
105 | M>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA839754 rs756197290 |
105 | M>V | No |
ClinGen ExAC gnomAD |
|
|
CA21995219 rs984434663 |
109 | L>P | No |
ClinGen TOPMed |
|
|
CA839751 rs761700780 CA340227014 |
110 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs1214603740 CA340226987 |
112 | S>* | No |
ClinGen TOPMed |
|
|
rs781570724 CA839726 |
114 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762298167 CA839724 |
116 | S>A | No |
ClinGen ExAC gnomAD |
|
|
rs774858456 CA839723 |
116 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA839722 rs142103959 |
117 | H>Y | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs749620894 CA839720 |
118 | G>A | No |
ClinGen ExAC gnomAD |
|
|
rs749620894 CA340226849 |
118 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA839718 rs770181502 |
120 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA839719 rs140759322 |
120 | Y>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 122 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1388832509 CA340226811 |
124 | A>T | No |
ClinGen TOPMed |
|
|
rs1304120415 CA340226798 |
125 | P>Q | No |
ClinGen TOPMed |
|
|
rs866137454 CA21994447 |
126 | W>* | No |
ClinGen Ensembl |
|
|
rs1403817268 CA340226784 |
126 | W>* | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 128 | G>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1202868022 CA340226688 |
128 | G>E | No |
ClinGen TOPMed gnomAD |
|
|
CA340226685 rs1202868022 |
128 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
CA340226668 rs62621075 |
130 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340226664 rs1241859582 |
130 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA839687 rs62621075 |
130 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340226661 rs1241859582 |
130 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
COSM70377 CA839686 rs144085677 CA839685 |
131 | L>F | ovary [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs776854909 CA839684 |
132 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839683 rs770936750 |
133 | L>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839681 rs777679381 |
134 | L>* | No |
ClinGen ExAC gnomAD |
|
|
rs748068075 CA839679 |
139 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs772044016 CA839680 |
139 | W>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1228210732 CA340226527 |
141 | Q>K | No |
ClinGen TOPMed |
|
|
CA340226522 rs1295857369 |
141 | Q>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA340226512 rs778748836 |
142 | H>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs778748836 CA839678 |
142 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839677 rs754705570 |
143 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs754705570 CA340226499 |
143 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839676 rs146269651 |
143 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs148717576 CA839672 |
144 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs148717576 CA839673 |
144 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
COSM3400854 CA839675 rs202214253 |
144 | R>W | Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1190661750 CA340226467 |
145 | M>I | No |
ClinGen gnomAD |
|
|
rs1570093117 CA340226454 |
147 | T>P | No |
ClinGen Ensembl |
|
|
rs1284404117 CA340226436 |
149 | A>T | No |
ClinGen gnomAD |
|
|
CA340226429 rs1374561910 |
149 | A>V | No |
ClinGen TOPMed |
|
|
CA21993625 rs925656596 |
152 | Y>N | No |
ClinGen TOPMed gnomAD |
|
|
rs932427056 CA21993614 |
155 | L>P | No |
ClinGen TOPMed gnomAD |
|
|
rs370673519 CA839669 |
157 | P>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs143639289 CA839667 |
158 | Y>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs143639289 CA340226300 |
158 | Y>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs760783129 CA839665 |
159 | V>E | No |
ClinGen ExAC gnomAD |
|
|
rs1557556740 CA340226292 |
159 | V>L | No |
ClinGen Ensembl |
|
|
rs773396769 CA839664 |
160 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs773396769 CA340226283 |
160 | G>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748084736 CA839662 |
161 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839661 rs778769075 |
162 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA340226260 rs1321654543 |
162 | M>V | No |
ClinGen TOPMed |
|
|
rs768465860 CA340226244 |
163 | A>P | No |
ClinGen ExAC gnomAD |
|
|
CA839660 rs768465860 |
163 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs768465860 CA340226246 |
163 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA839659 rs749071464 |
164 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839658 rs199858866 |
167 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839656 rs144065752 |
167 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs144065752 CA839657 |
167 | R>Q | Variant assessed as Somatic; 4.719e-05 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA839655 rs780851577 |
168 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs1268786413 CA340226181 |
169 | M>L | No |
ClinGen gnomAD |
|
|
CA340226178 rs1481908545 |
169 | M>T | No |
ClinGen gnomAD |
|
|
CA839653 rs753277901 |
170 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs1470697523 CA340225847 |
173 | W>C | No |
ClinGen TOPMed gnomAD |
|
|
rs143018352 CA839629 |
175 | E>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 176 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1570085983 CA340225819 |
178 | G>S | No |
ClinGen Ensembl |
|
|
rs536870781 CA839627 |
179 | Q>* | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs764147276 CA839626 |
181 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA340225792 rs1212352634 |
182 | P>S | No |
ClinGen gnomAD |
|
| TCGA novel | 183 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs144945108 CA839625 |
183 | L>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
COSM117420 CA839624 rs62618709 |
185 | V>F | ovary large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA839623 rs769652273 |
188 | H>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 189 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs140345183 CA839621 |
189 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs770751722 COSM3735358 CA839620 |
190 | S>F | skin [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs777489918 CA839618 CA340225723 |
192 | M>I | No |
ClinGen ExAC gnomAD |
|
|
rs1401815800 CA340225699 |
196 | T>S | No |
ClinGen gnomAD |
|
|
CA839616 rs749817925 |
197 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA340225686 rs1180197593 |
198 | M>R | No |
ClinGen TOPMed |
|
|
rs780379911 CA839615 |
200 | C>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839614 rs143503396 |
200 | C>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839613 rs776305178 |
201 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 205 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs757534980 CA839611 |
205 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs148545122 CA839609 |
206 | G>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839610 rs151044753 |
206 | G>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs868672389 CA340225624 |
207 | S>I | No |
ClinGen TOPMed |
|
|
rs868672389 CA21992091 COSM910371 |
207 | S>N | Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs551730881 CA839606 |
208 | I>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 209 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA839605 rs759491535 |
210 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA340225601 rs539428854 |
211 | D>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs539428854 CA839604 |
211 | D>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs539428854 CA839603 |
211 | D>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 214 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 217 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1309951857 CA340225472 |
218 | I>L | No |
ClinGen gnomAD |
|
|
rs12759935 CA21991724 |
218 | I>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs752955975 CA839569 |
220 | A>G | No |
ClinGen ExAC gnomAD |
|
|
CA839568 rs757542967 |
223 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340225372 rs1248472770 |
223 | D>G | No |
ClinGen TOPMed |
|
| TCGA novel | 223 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA839567 rs778859771 |
225 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
VAR_048452 CA839566 rs12759923 |
226 | N>S | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA839564 rs766382814 |
228 | V>D | No |
ClinGen ExAC gnomAD |
|
|
CA340225294 COSM1343177 rs753851320 |
228 | V>F | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs753851320 CA839565 |
228 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA839563 rs376499620 |
229 | F>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839561 rs12734875 |
230 | S>C | No |
ClinGen Ensembl |
|
|
rs750238866 CA839560 |
231 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761443544 CA839558 |
231 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761443544 CA839559 |
231 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750238866 CA340225247 |
231 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839555 rs372832923 |
232 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed |
|
rs763609518 CA839556 |
232 | V>M | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 233 | R>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs944833809 CA21991625 |
234 | N>D | No |
ClinGen TOPMed |
|
|
CA839554 CA340225193 rs201947604 |
234 | N>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1417048390 CA340225189 |
235 | A>T | No |
ClinGen gnomAD |
|
|
rs1371775097 CA340225179 |
235 | A>V | No |
ClinGen TOPMed |
|
|
rs866787428 CA21991618 |
237 | H>Y | No |
ClinGen Ensembl |
|
|
CA839552 rs147970101 |
238 | Q>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1359013789 CA340225145 |
238 | Q>P | No |
ClinGen TOPMed |
|
|
rs1570081326 CA340225130 |
240 | D>A | No |
ClinGen Ensembl |
|
|
CA839551 COSM106662 rs143292347 |
240 | D>N | skin [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA340225120 rs1202500101 |
241 | T>I | No |
ClinGen gnomAD |
|
|
CA340225125 rs1570081271 |
241 | T>P | No |
ClinGen Ensembl |
|
|
CA340225116 rs1345188629 |
242 | I>N | No |
ClinGen gnomAD |
|
|
CA340225115 rs1345188629 |
242 | I>T | No |
ClinGen gnomAD |
|
|
CA340225119 rs1557553896 |
242 | I>V | No |
ClinGen Ensembl |
|
|
CA340225111 rs1200057250 |
243 | Y>H | No |
ClinGen gnomAD |
|
|
rs370227361 CA839550 |
244 | S>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839549 rs370227361 |
244 | S>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs779145316 CA839548 |
246 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs779145316 CA340225093 |
246 | T>P | No |
ClinGen ExAC gnomAD |
|
|
rs1335527950 CA340225067 |
247 | S>F | No |
ClinGen TOPMed gnomAD |
|
|
rs1189078901 CA839546 |
250 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs1189078901 CA340225035 |
250 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
rs140272422 CA839544 |
250 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs140272422 CA839545 |
250 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1449188327 CA340225021 |
251 | W>R | No |
ClinGen gnomAD |
|
|
CA21991562 rs144757469 |
253 | H>D | No |
ClinGen ESP ExAC TOPMed |
|
|
rs756182951 CA839542 |
253 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs144757469 CA839543 |
253 | H>Y | No |
ClinGen ESP ExAC TOPMed |
|
|
CA839541 rs372123144 |
254 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs145085638 CA839540 |
254 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs145085638 CA839538 |
254 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839539 rs145085638 |
254 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839536 rs374070893 |
255 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs370693795 CA839535 |
256 | C>G | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1362970802 CA340224935 |
256 | C>S | No |
ClinGen gnomAD |
|
|
rs533408902 CA340224903 |
259 | A>D | No |
ClinGen 1000Genomes |
|
|
rs1441096346 CA340224904 |
259 | A>S | No |
ClinGen gnomAD |
|
|
rs1441096346 CA340224906 |
259 | A>T | No |
ClinGen gnomAD |
|
|
rs533408902 CA21991519 |
259 | A>V | No |
ClinGen 1000Genomes |
|
|
CA340224896 rs1450753801 |
260 | H>Q | No |
ClinGen TOPMed |
|
|
CA839533 rs144737664 |
260 | H>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA839531 rs772344650 |
262 | H>Q | No |
ClinGen ExAC |
|
|
rs1442470366 CA340224874 |
263 | T>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA340224847 rs1440585485 |
264 | D>E | No |
ClinGen TOPMed |
|
|
rs746940127 CA839503 |
267 | I>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340224815 rs1226768225 |
268 | Q>L | No |
ClinGen TOPMed gnomAD |
|
|
CA340224814 rs1226768225 |
268 | Q>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1341279967 CA522613728 |
269 | L>* | No |
ClinGen gnomAD |
|
|
CA522613727 rs1298701856 |
269 | L>P | No |
ClinGen gnomAD |
|
|
CA340224808 rs1459545426 |
269 | L>V | No |
ClinGen TOPMed |
|
|
CA839501 CA340224786 rs758130015 |
271 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752367699 CA839500 |
272 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1377308833 CA340224780 |
272 | A>V | No |
ClinGen TOPMed |
|
| TCGA novel | 273 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA340224767 rs1405528293 |
274 | L>I | No |
ClinGen gnomAD |
|
|
CA839498 rs41300339 |
276 | K>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA839495 CA839496 rs147306446 |
278 | G>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs752049616 CA839494 |
279 | E>A | No |
ClinGen ExAC gnomAD |
|
|
rs1196409448 CA340224727 |
279 | E>K | No |
ClinGen gnomAD |
|
|
rs1196409448 CA340224726 |
279 | E>Q | No |
ClinGen gnomAD |
|
|
rs201985706 CA839493 |
281 | E>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1570077138 CA340224696 COSM910370 |
282 | K>N | endometrium [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
CA839492 rs763364483 |
282 | K>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775888309 CA839491 |
283 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340224693 rs1453748253 |
283 | I>V | No |
ClinGen gnomAD |
|
|
CA340224660 rs1557552744 |
287 | R>G | No |
ClinGen Ensembl |
|
|
rs1318673733 CA340224650 |
288 | H>D | No |
ClinGen TOPMed gnomAD |
|
|
CA340224651 rs1318673733 |
288 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs776835348 CA839488 |
290 | D>H | No |
ClinGen ExAC gnomAD |
|
|
rs776835348 CA839489 |
290 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1274239738 CA340224605 |
293 | D>G | No |
ClinGen gnomAD |
|
|
CA839486 rs770844748 |
294 | I>S | No |
ClinGen ExAC gnomAD |
|
|
rs1326417961 CA340224593 |
295 | L>I | No |
ClinGen gnomAD |
|
|
rs777637899 CA839484 |
296 | L>F | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 296 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA839483 rs561884452 |
296 | L>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA21990909 rs369378406 |
298 | A>T | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA340224559 rs1570076592 |
298 | A>V | No |
ClinGen Ensembl |
|
|
CA839480 rs778552906 |
299 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
CA340224494 rs1354235162 |
300 | M>T | No |
ClinGen gnomAD |
|
|
CA340224481 rs774270128 |
301 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839462 rs774270128 |
301 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340224448 rs1170019286 |
303 | G>A | No |
ClinGen gnomAD |
|
| TCGA novel | 304 | S>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA340224439 rs1450075446 |
304 | S>N | No |
ClinGen gnomAD |
|
|
CA340224414 CA839459 rs148595946 |
306 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839461 rs768269358 |
306 | L>S | No |
ClinGen ExAC gnomAD |
|
|
CA839457 rs373052526 |
308 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA839458 rs564592694 |
308 | D>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA340224396 rs564592694 |
308 | D>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA839456 rs780833068 |
312 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839455 COSM910369 rs759038433 |
312 | R>H | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs753074193 CA839454 |
313 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839453 rs368780307 |
314 | E>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs755248704 CA839452 |
317 | T>M | No |
ClinGen ExAC gnomAD |
|
|
rs766548408 CA839450 |
321 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs28451040 CA839448 |
323 | H>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA340224192 rs1260930883 |
323 | H>Y | No |
ClinGen gnomAD |
|
|
CA340224174 rs1488482611 |
324 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1242115353 CA340224153 |
325 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1287927918 CA340224161 |
325 | T>P | No |
ClinGen gnomAD |
|
|
rs1242115353 CA340224155 |
325 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
CA340224143 rs1229530724 |
326 | T>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA340224151 rs1312742291 |
326 | T>P | No |
ClinGen gnomAD |
|
| TCGA novel | 329 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs866909219 CA21990632 |
329 | G>R | No |
ClinGen Ensembl |
|
|
rs377315921 CA839446 |
329 | G>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs761743285 CA839445 |
330 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs141672858 CA839444 |
331 | S>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA340224052 rs1301679681 |
333 | I>N | No |
ClinGen gnomAD |
|
| TCGA novel | 333 | I>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1457543611 CA340224039 |
334 | L>F | No |
ClinGen gnomAD |
|
|
CA839442 rs749000785 |
334 | L>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340224038 rs749000785 |
334 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs541805813 CA839441 |
336 | A>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs541805813 CA839440 |
336 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs756765536 CA839437 |
340 | H>D | No |
ClinGen ExAC gnomAD |
|
|
rs779248380 CA839435 |
341 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1570074195 CA340223935 |
343 | H>P | No |
ClinGen Ensembl |
|
|
CA839432 rs780385066 |
344 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs754203259 CA839433 |
344 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340223926 rs1223374182 |
345 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA340223923 rs1188242633 |
345 | E>V | No |
ClinGen gnomAD |
|
|
CA340223916 rs1315469922 |
346 | R>K | No |
ClinGen gnomAD |
|
|
CA839428 rs187003693 |
348 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed |
|
|
CA340223902 rs187003693 |
348 | R>P | No |
ClinGen 1000Genomes ExAC TOPMed |
|
|
CA839429 rs187003693 |
348 | R>Q | No |
ClinGen 1000Genomes ExAC TOPMed |
|
|
CA839430 rs148022251 |
348 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA340223875 rs1342950209 |
352 | H>P | No |
ClinGen gnomAD |
|
|
CA340223878 rs1570073858 |
352 | H>Y | No |
ClinGen Ensembl |
|
|
rs3899049 CA340223869 |
353 | S>C | No |
ClinGen TOPMed gnomAD |
|
|
CA21990494 VAR_044377 rs3899049 |
353 | S>G | No |
ClinGen UniProt TOPMed dbSNP gnomAD |
|
|
rs751551682 CA839427 |
353 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1370317282 CA340223862 |
354 | L>F | No |
ClinGen TOPMed |
|
|
CA839426 rs148894365 |
355 | L>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1460681350 CA340223857 |
355 | L>V | No |
ClinGen gnomAD |
|
|
rs369208625 CA340223854 |
356 | G>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369208625 CA839424 |
356 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369208625 CA839425 |
356 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA839423 rs769643633 |
357 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA839422 rs759270614 |
357 | D>V | No |
ClinGen ExAC gnomAD |
|
|
rs530295909 CA340223836 |
359 | A>D | No |
ClinGen ExAC gnomAD |
|
|
rs372803840 COSM1687629 CA839420 |
359 | A>T | skin [Cosmic] | No |
ClinGen cosmic curated ESP ExAC gnomAD |
|
rs530295909 CA839419 |
359 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs769099199 CA839417 |
361 | I>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839418 rs769099199 |
361 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839416 rs144597719 |
362 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 363 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA839392 rs138802237 |
364 | N>D | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA340223672 rs1458961273 |
365 | H>Q | No |
ClinGen TOPMed |
|
|
CA340223667 rs1379508152 |
366 | L>P | No |
ClinGen gnomAD |
|
|
rs765304868 CA839389 |
370 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1163359492 CA340223622 |
372 | T>I | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 373 | T>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs754944564 CA839388 |
373 | T>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1258872255 CA340223615 |
374 | M>L | No |
ClinGen gnomAD |
|
|
CA839387 rs753742359 |
375 | C>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs954816685 CA21990204 |
375 | C>Y | No |
ClinGen TOPMed |
|
|
CA340223576 rs1467575085 |
379 | A>E | No |
ClinGen TOPMed |
|
|
CA839386 rs766191296 |
379 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1467575085 CA340223574 |
379 | A>V | No |
ClinGen TOPMed |
|
|
rs760250627 CA839385 |
381 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs919229398 CA21990191 |
382 | L>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA340223560 rs772865981 |
382 | L>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM464711 CA839384 rs772865981 |
382 | L>P | kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA839383 rs58590117 COSM2150236 |
385 | P>L | Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA839381 rs142464883 |
386 | V>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA839380 rs770339224 |
388 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1359618339 CA340223519 |
389 | I>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs777049863 CA839377 |
393 | L>I | No |
ClinGen ExAC gnomAD |
|
|
rs1162357390 CA340223487 |
394 | S>N | No |
ClinGen TOPMed gnomAD |
|
|
rs1472825359 CA340223478 |
395 | T>S | No |
ClinGen gnomAD |
|
|
rs1477234945 CA340223471 |
396 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs778007925 CA839374 |
397 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs958885594 CA21990090 |
399 | F>L | No |
ClinGen TOPMed |
|
|
rs1264271732 CA340223447 |
400 | P>L | No |
ClinGen gnomAD |
|
|
CA340223439 rs1168855507 |
401 | D>E | No |
ClinGen TOPMed |
|
|
CA340223445 rs1479057076 |
401 | D>H | No |
ClinGen TOPMed |
|
|
CA839372 rs748287772 |
402 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA839373 rs758517485 |
402 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs779120313 CA839371 COSM1737082 |
403 | R>C | central_nervous_system [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs756586563 CA21990052 |
403 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
CA839370 rs150346297 |
404 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs374588379 CA839367 |
406 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA839369 rs766102280 |
406 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839368 rs766102280 |
406 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA21990024 rs1003098093 |
407 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
rs1241490270 CA340223412 |
407 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
rs560044999 CA839366 |
408 | G>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs756993562 CA340223396 |
408 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs756993562 CA839329 |
408 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA340223388 rs1288247586 |
409 | I>M | No |
ClinGen gnomAD |
|
|
CA839328 rs777439629 CA839327 |
410 | M>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1359071414 CA340223378 |
411 | V>F | No |
ClinGen gnomAD |
|
|
CA340223374 rs1335492629 |
412 | L>F | No |
ClinGen gnomAD |
|
|
CA839326 rs758021306 |
412 | L>H | No |
ClinGen ExAC gnomAD |
|
|
CA839325 rs752308062 |
413 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs764647471 CA839324 |
415 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA340223349 rs1570063217 |
416 | Y>C | No |
ClinGen Ensembl |
|
|
CA21988742 rs772116129 |
417 | G>R | No |
ClinGen gnomAD |
|
|
CA21988738 rs1014674360 |
418 | L>I | No |
ClinGen TOPMed |
|
|
rs375258408 CA340223327 CA340223328 |
419 | H>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 419 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 422 | P>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs750836457 CA839322 |
422 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs750836457 CA340223309 |
422 | P>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 423 | K>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA839320 rs550368607 |
423 | K>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA839319 rs774827023 CA839318 |
424 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340223298 rs774827023 |
424 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764460830 CA839317 |
425 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs1284458106 CA340223291 |
425 | W>S | No |
ClinGen gnomAD |
|
|
CA839314 rs769700393 |
427 | N>H | No |
ClinGen ExAC gnomAD |
|
|
rs150667037 CA839313 |
428 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs150667037 CA21988657 |
428 | P>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA340223268 rs1343185691 |
429 | E>Q | No |
ClinGen gnomAD |
|
|
CA340223248 rs1291945566 |
430 | V>A | No |
ClinGen gnomAD |
|
|
CA340223250 rs1416004924 |
430 | V>L | No |
ClinGen gnomAD |
|
|
rs1457599116 CA340223243 |
431 | F>Y | No |
ClinGen gnomAD |
|
|
rs772994318 CA839290 |
432 | D>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839289 rs138925154 |
433 | P>R | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1126742 CA839287 VAR_019160 |
434 | F>S | associated with hypertension; significantly reduced arachidonic acid and lauric acid metabolizing activity [UniProt] | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
rs142881303 CA839285 COSM1748487 |
435 | R>C | urinary_tract [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA839284 COSM3805469 rs199678286 |
435 | R>H | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA839286 rs142881303 |
435 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA340223209 rs779699972 |
436 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs1171226914 CA340223206 |
437 | A>S | No |
ClinGen TOPMed |
|
|
rs1189024958 CA340223202 |
438 | P>A | No |
ClinGen gnomAD |
|
|
CA839282 rs373468480 |
438 | P>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs764571042 CA839280 |
439 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753070622 CA839278 |
440 | S>C | No |
ClinGen ExAC gnomAD |
|
|
rs1228811515 CA340223187 |
441 | A>P | No |
ClinGen gnomAD |
|
|
rs1309565791 CA340223179 |
442 | Q>* | No |
ClinGen gnomAD |
|
|
rs759789388 CA839276 |
443 | H>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1371972329 CA340223156 |
445 | H>Y | No |
ClinGen gnomAD |
|
|
COSM189843 rs556756716 CA839274 |
446 | A>T | lung Variant assessed as Somatic; 0.0 impact. large_intestine [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA340223138 rs1399721304 |
447 | F>L | No |
ClinGen gnomAD |
|
|
CA839273 rs544836341 |
449 | P>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1327283629 CA340223121 |
450 | F>L | No |
ClinGen TOPMed |
|
|
rs1462435616 CA340223105 |
453 | G>* | No |
ClinGen gnomAD |
|
|
rs771932669 CA839271 |
453 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA839272 rs771932669 |
453 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs1233776645 CA340223102 |
454 | S>P | No |
ClinGen TOPMed |
|
|
rs1313221822 CA340223097 |
455 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1454880450 CA340222691 |
456 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
CA839241 rs754090038 |
456 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA340222680 rs1467990808 |
458 | I>F | No |
ClinGen gnomAD |
|
|
rs1126743 CA21986313 |
458 | I>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs780295129 CA839240 |
458 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs767632502 CA21986304 |
459 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs750528497 CA839238 CA340222677 |
459 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs767632502 CA839237 |
459 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs942325999 CA21986303 |
460 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
CA340222670 rs1171626952 |
460 | K>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1171626952 CA340222672 |
460 | K>T | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 461 | Q>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1264970774 CA340222639 |
464 | M>I | No |
ClinGen gnomAD |
|
|
rs1207136796 CA340222645 |
464 | M>L | No |
ClinGen gnomAD |
|
|
rs200205845 CA839236 |
464 | M>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs763821466 CA839235 |
465 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA340222633 rs1240084416 |
465 | N>S | No |
ClinGen TOPMed |
|
|
rs531039219 CA839233 |
466 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs531039219 CA839232 |
466 | E>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs1248192186 CA340222607 |
469 | V>A | No |
ClinGen TOPMed |
|
| TCGA novel | 469 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA839231 rs765037022 |
470 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs146063263 CA839230 |
471 | T>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA839229 rs146063263 |
471 | T>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA839227 rs748622926 |
472 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839225 rs551830245 |
473 | L>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA839224 rs749702088 |
474 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749702088 CA340222583 |
474 | T>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA839222 rs150500700 |
477 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs148423796 CA839221 |
477 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA340222538 rs1195546038 |
482 | P>L | No |
ClinGen gnomAD |
|
|
rs781148259 CA839220 |
483 | D>A | No |
ClinGen ExAC gnomAD |
|
|
rs1267000192 COSM3805466 CA340222527 |
484 | P>A | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA839219 rs367938890 |
486 | R>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA340222502 rs1429728247 |
488 | P>A | No |
ClinGen TOPMed |
|
|
CA340222487 rs1274960664 |
490 | P>R | No |
ClinGen gnomAD |
|
|
rs1399172771 CA340222488 |
490 | P>S | No |
ClinGen TOPMed |
|
|
rs148507594 CA839217 |
491 | I>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA340222480 COSM3805465 rs1216734147 |
491 | I>T | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA340222477 rs1333769898 |
492 | A>T | No |
ClinGen TOPMed |
|
|
CA839216 rs758392577 |
493 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs151272902 CA839215 |
493 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1440991817 CA340222467 |
494 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
rs562189386 CA839212 |
495 | V>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs759121794 CA839213 |
495 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA21986034 rs866450703 |
498 | S>F | No |
ClinGen Ensembl |
|
| TCGA novel | 500 | N>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| VAR_001257 | 500 | N>MESTCVSGGSLTLVKTRTSFEGLHLPSCLPDPRFCPLPVCPYPVFCLPTFPSSHLPAVPQSACPSLSHLSPGLPTCLSTCLLPTCISCWEKS | CYP4A11V [UniProt] | No | UniProt |
|
CA340222427 rs1409930212 |
500 | N>S | No |
ClinGen gnomAD |
|
|
CA340222413 rs1570042879 |
502 | I>T | No |
ClinGen Ensembl |
|
|
CA340222416 rs1420608451 |
502 | I>V | No |
ClinGen gnomAD |
|
|
CA340222407 rs1570042847 |
503 | H>P | No |
ClinGen Ensembl |
|
|
CA839211 COSM3400852 rs765836836 |
505 | R>C | Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA340222396 rs765836836 |
505 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs144175060 CA839210 |
505 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA839209 rs58897090 COSM4144052 |
506 | L>F | thyroid [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs1557545217 CA340222385 |
507 | R>T | No |
ClinGen Ensembl |
|
|
CA839207 rs149532035 |
509 | L>F | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs149532035 CA340222374 |
509 | L>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA21986018 rs374049336 |
509 | L>R | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA839208 rs149532035 |
509 | L>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs564367884 CA839205 |
510 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs775839465 CA839206 |
510 | P>T | No |
ClinGen ExAC gnomAD |
|
|
rs746103752 CA839204 |
511 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA340222364 rs746103752 |
511 | N>T | No |
ClinGen ExAC gnomAD |
|
|
rs139114509 CA839202 |
512 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA340222352 rs1332375340 |
513 | C>Y | No |
ClinGen gnomAD |
|
|
CA340222336 rs1159038307 |
515 | D>G | No |
ClinGen Ensembl |
|
|
CA839201 rs747166920 |
519 | L>F | No |
ClinGen ExAC gnomAD |
No associated diseases with Q02928
1 regional properties for Q02928
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cytochrome P450, conserved site | 450 - 459 | IPR017972 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.14.1 | With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| apical plasma membrane | The region of the plasma membrane located at the apical end of the cell. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
9 GO annotations of molecular function
| Name | Definition |
|---|---|
| alkane 1-monooxygenase activity | Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O. |
| arachidonic acid epoxygenase activity | Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid. |
| arachidonic acid monooxygenase activity | Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water. |
| aromatase activity | Catalysis of the reduction of an aliphatic ring to yield an aromatic ring. |
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
| leukotriene-B4 20-monooxygenase activity | Catalysis of the reaction: leukotriene B4 + O2 + reduced |
| long-chain fatty acid omega-hydroxylase activity | Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced = an omega-hydroxy-long-chain fatty acid + H(+) + H2O + oxidized |
| monooxygenase activity | Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. |
15 GO annotations of biological process
| Name | Definition |
|---|---|
| arachidonic acid metabolic process | The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. |
| epoxygenase P450 pathway | The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids. |
| fatty acid metabolic process | The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. |
| icosanoid biosynthetic process | The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids. |
| kidney development | The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. |
| lauric acid metabolic process | The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources. |
| leukotriene metabolic process | The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. |
| linoleic acid metabolic process | The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. |
| long-chain fatty acid metabolic process | The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. |
| omega-hydroxylase P450 pathway | The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation. |
| oxylipin biosynthetic process | The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids. |
| positive regulation of icosanoid secretion | Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell. |
| pressure natriuresis | The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis). |
| renal water homeostasis | Renal process involved in the maintenance of an internal steady state of water in the body. |
| sodium ion homeostasis | Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell. |
38 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VYQ5 | Cyp318a1 | Probable cytochrome P450 318a1 | Drosophila melanogaster (Fruit fly) | PR |
| Q9V7G5 | Cyp4aa1 | Probable cytochrome P450 4aa1 | Drosophila melanogaster (Fruit fly) | PR |
| Q9VVN6 | Cyp312a1 | Probable cytochrome P450 312a1 | Drosophila melanogaster (Fruit fly) | PR |
| Q9VXY0 | Cyp4s3 | Probable cytochrome P450 4s3 | Drosophila melanogaster (Fruit fly) | PR |
| Q9VMS8 | Cyp4ac2 | Probable cytochrome P450 4ac2 | Drosophila melanogaster (Fruit fly) | PR |
| Q9VMS7 | Cyp4ac3 | Probable cytochrome P450 4ac3 | Drosophila melanogaster (Fruit fly) | PR |
| Q9V559 | Cyp4p3 | Probable cytochrome P450 4p3 | Drosophila melanogaster (Fruit fly) | PR |
| Q6ZWL3 | CYP4V2 | Cytochrome P450 4V2 | Homo sapiens (Human) | PR |
| Q86W10 | CYP4Z1 | Cytochrome P450 4Z1 | Homo sapiens (Human) | PR |
| Q5TCH4 | CYP4A22 | Cytochrome P450 4A22 | Homo sapiens (Human) | PR |
| P13584 | CYP4B1 | Cytochrome P450 4B1 | Homo sapiens (Human) | PR |
| B6SSW8 | CYP714B3 | Cytochrome P450 714B3 | Zea mays (Maize) | PR |
| O35728 | Cyp4a14 | Cytochrome P450 4A14 | Mus musculus (Mouse) | PR |
| Q91WL5 | Cyp4a12a | Cytochrome P450 4A12A | Mus musculus (Mouse) | PR |
| Q9GJX5 | CYP4A21 | Taurochenodeoxycholic 6 alpha-hydroxylase | Sus scrofa (Pig) | PR |
| Q8SPK1 | CYP4A24 | Cytochrome P450 4A24 | Sus scrofa (Pig) | PR |
| Q8SPK0 | CYP4A25 | Cytochrome P450 4A25 | Sus scrofa (Pig) | PR |
| G3V7X8 | Cyp26b1 | Cytochrome P450 26B1 | Rattus norvegicus (Rat) | PR |
| P20816 | Cyp4a2 | Cytochrome P450 4A2 | Rattus norvegicus (Rat) | PR |
| P20817 | Cyp4a14 | Cytochrome P450 4A14 | Rattus norvegicus (Rat) | PR |
| P24464 | Cyp4a12 | Cytochrome P450 4A12 | Rattus norvegicus (Rat) | PR |
| Q05JG2 | CYP707A5 | Abscisic acid 8'-hydroxylase 1 | Oryza sativa subsp japonica (Rice) | PR |
| Q6F4F5 | CYP724B1 | Cytochrome P450 724B1 | Oryza sativa subsp japonica (Rice) | PR |
| Q0DS59 | CYP714B2 | Cytochrome P450 714B2 | Oryza sativa subsp japonica (Rice) | PR |
| Q5KQH7 | CYP714D1 | Cytochrome P450 714D1 | Oryza sativa subsp japonica (Rice) | PR |
| Q9C788 | CYP704B1 | Cytochrome P450 704B1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZUX1 | CYP94C1 | Cytochrome P450 94C1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81077 | CYP707A2 | Abscisic acid 8'-hydroxylase 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O64698 | CYP710A2 | Cytochrome P450 710A2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O64697 | CYP710A1 | Cytochrome P450 710A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94IA6 | CYP90D1 | 3-epi-6-deoxocathasterone 23-monooxygenase CYP90D1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q6TBX7 | CYP97C1 | Carotene epsilon-monooxygenase, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUC5 | CYP72A15 | Cytochrome P450 72A15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUC6 | CYP72A14 | Cytochrome P450 72A14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUC8 | CYP72A13 | Cytochrome P450 72A13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUC9 | CYP72A11 | Cytochrome P450 72A11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SHG5 | CYP72C1 | Cytochrome P450 72C1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q6EIG3 | cyp26b1 | Cytochrome P450 26B1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVSVLSPSR | LLGDVSGILQ | AASLLILLLL | LIKAVQLYLH | RQWLLKALQQ | FPCPPSHWLF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GHIQELQQDQ | ELQRIQKWVE | TFPSACPHWL | WGGKVRVQLY | DPDYMKVILG | RSDPKSHGSY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RFLAPWIGYG | LLLLNGQTWF | QHRRMLTPAF | HYDILKPYVG | LMADSVRVML | DKWEELLGQD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SPLEVFQHVS | LMTLDTIMKC | AFSHQGSIQV | DRNSQSYIQA | ISDLNNLVFS | RVRNAFHQND |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TIYSLTSAGR | WTHRACQLAH | QHTDQVIQLR | KAQLQKEGEL | EKIKRKRHLD | FLDILLLAKM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ENGSILSDKD | LRAEVDTFMF | EGHDTTASGI | SWILYALATH | PKHQERCREE | IHSLLGDGAS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ITWNHLDQMP | YTTMCIKEAL | RLYPPVPGIG | RELSTPVTFP | DGRSLPKGIM | VLLSIYGLHH |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NPKVWPNPEV | FDPFRFAPGS | AQHSHAFLPF | SGGSRNCIGK | QFAMNELKVA | TALTLLRFEL |
| 490 | 500 | 510 | |||
| LPDPTRIPIP | IARLVLKSKN | GIHLRLRRLP | NPCEDKDQL |