Q9C788

PR
Gene name
CYP704B1 (At1g69500, F10D13.15)
Protein name
Cytochrome P450 704B1
Names
Long-chain fatty acid omega-hydroxylase
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G69500
EC number
1.14.14.80: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

224-295 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9C788

Entry ID Method Resolution Chain Position Source
AF-Q9C788-F1 Predicted AlphaFoldDB

54 variants for Q9C788

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_26123971_T_G 4 C>W No 1000Genomes
tmp_1_26123975_G_C 6 V>L No 1000Genomes
tmp_1_26124027_G_A 23 R>K No 1000Genomes
ENSVATH01507434 25 K>N No 1000Genomes
tmp_1_26124117_A_C 53 E>A No 1000Genomes
tmp_1_26124138_C_T 60 T>I No 1000Genomes
tmp_1_26124156_C_T 66 P>L No 1000Genomes
ENSVATH13775273 72 Y>F No 1000Genomes
tmp_1_26124188_A_G 77 I>V No 1000Genomes
tmp_1_26124432_T_A 134 D>E No 1000Genomes
tmp_1_26124439_A_T 137 T>S No 1000Genomes
ENSVATH01507447 149 T>N No 1000Genomes
ENSVATH05109377 157 K>R No 1000Genomes
ENSVATH01507449 158 E>D No 1000Genomes
ENSVATH05109378 159 Q>K No 1000Genomes
ENSVATH05109384 166 L>F No 1000Genomes
tmp_1_26124605_G_A 168 M>I No 1000Genomes
ENSVATH13775276 203 A>T No 1000Genomes
tmp_1_26124755_G_A 218 M>I No 1000Genomes
tmp_1_26124753_A_T 218 M>L No 1000Genomes
tmp_1_26124763_T_C 221 F>S No 1000Genomes
tmp_1_26124770_C_G 223 N>K No 1000Genomes
tmp_1_26124826_A_T 242 Y>F No 1000Genomes
ENSVATH01507461 257 I>K No 1000Genomes
ENSVATH05109390 259 P>A No 1000Genomes
ENSVATH05109390 259 P>S No 1000Genomes
ENSVATH05109392 263 N>I No 1000Genomes
ENSVATH05109393 263 N>K No 1000Genomes
tmp_1_26125057_G_T 291 E>D No 1000Genomes
ENSVATH05109400 297 I>V No 1000Genomes
tmp_1_26125133_A_T 317 I>L No 1000Genomes
tmp_1_26125155_A_G 324 E>G No 1000Genomes
tmp_1_26125172_C_A 330 L>I No 1000Genomes
tmp_1_26125183_G_C 333 E>D No 1000Genomes
ENSVATH00133413 335 Q>H No 1000Genomes
ENSVATH05109403 345 T>I No 1000Genomes
tmp_1_26125224_C_T 347 T>I No 1000Genomes
tmp_1_26125227_C_T 348 S>L No 1000Genomes
ENSVATH05109404 351 Q>L No 1000Genomes
ENSVATH01507465 353 D>E No 1000Genomes
ENSVATH01507464 353 D>N No 1000Genomes
ENSVATH00133415 358 N>S No 1000Genomes
ENSVATH00133415 358 N>T No 1000Genomes
ENSVATH05109406 365 T>S No 1000Genomes
ENSVATH05109408 368 A>T No 1000Genomes
tmp_1_26125306_T_G 374 D>E No 1000Genomes
ENSVATH01507466 378 K>T No 1000Genomes
tmp_1_26125584_T_G 441 L>V No 1000Genomes
tmp_1_26125614_G_A 451 G>R No 1000Genomes
tmp_1_26125784_G_A 484 A>T No 1000Genomes
tmp_1_26125809_A_G 492 Y>C No 1000Genomes
tmp_1_26125811_A_G 493 K>E No 1000Genomes
ENSVATH05109432 520 V>L No 1000Genomes
tmp_1_26125896_C_G 521 S>C No 1000Genomes

No associated diseases with Q9C788

No regional properties for Q9C788

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9C788

Functions

Description
EC Number 1.14.14.80 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
alkane 1-monooxygenase activity Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
long-chain fatty acid omega-hydroxylase activity Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced = an omega-hydroxy-long-chain fatty acid + H(+) + H2O + oxidized

2 GO annotations of biological process

Name Definition
pollen exine formation The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.
sporopollenin biosynthetic process The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.

36 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VYQ5 Cyp318a1 Probable cytochrome P450 318a1 Drosophila melanogaster (Fruit fly) PR
Q9VXY0 Cyp4s3 Probable cytochrome P450 4s3 Drosophila melanogaster (Fruit fly) PR
Q9VMS7 Cyp4ac3 Probable cytochrome P450 4ac3 Drosophila melanogaster (Fruit fly) PR
Q9V559 Cyp4p3 Probable cytochrome P450 4p3 Drosophila melanogaster (Fruit fly) PR
Q9V7G5 Cyp4aa1 Probable cytochrome P450 4aa1 Drosophila melanogaster (Fruit fly) PR
Q9VMS8 Cyp4ac2 Probable cytochrome P450 4ac2 Drosophila melanogaster (Fruit fly) PR
Q9VVN6 Cyp312a1 Probable cytochrome P450 312a1 Drosophila melanogaster (Fruit fly) PR
Q02928 CYP4A11 Cytochrome P450 4A11 Homo sapiens (Human) PR
Q86W10 CYP4Z1 Cytochrome P450 4Z1 Homo sapiens (Human) PR
Q5TCH4 CYP4A22 Cytochrome P450 4A22 Homo sapiens (Human) PR
P13584 CYP4B1 Cytochrome P450 4B1 Homo sapiens (Human) PR
Q6ZWL3 CYP4V2 Cytochrome P450 4V2 Homo sapiens (Human) PR
B6SSW8 CYP714B3 Cytochrome P450 714B3 Zea mays (Maize) PR
O35728 Cyp4a14 Cytochrome P450 4A14 Mus musculus (Mouse) PR
Q91WL5 Cyp4a12a Cytochrome P450 4A12A Mus musculus (Mouse) PR
Q9GJX5 CYP4A21 Taurochenodeoxycholic 6 alpha-hydroxylase Sus scrofa (Pig) PR
Q8SPK1 CYP4A24 Cytochrome P450 4A24 Sus scrofa (Pig) PR
P24464 Cyp4a12 Cytochrome P450 4A12 Rattus norvegicus (Rat) PR
G3V7X8 Cyp26b1 Cytochrome P450 26B1 Rattus norvegicus (Rat) PR
P20816 Cyp4a2 Cytochrome P450 4A2 Rattus norvegicus (Rat) PR
Q05JG2 CYP707A5 Abscisic acid 8'-hydroxylase 1 Oryza sativa subsp japonica (Rice) PR
Q0DS59 CYP714B2 Cytochrome P450 714B2 Oryza sativa subsp japonica (Rice) PR
Q6F4F5 CYP724B1 Cytochrome P450 724B1 Oryza sativa subsp japonica (Rice) PR
Q5KQH7 CYP714D1 Cytochrome P450 714D1 Oryza sativa subsp japonica (Rice) PR
Q9SHG5 CYP72C1 Cytochrome P450 72C1 Arabidopsis thaliana (Mouse-ear cress) PR
O81077 CYP707A2 Abscisic acid 8'-hydroxylase 2 Arabidopsis thaliana (Mouse-ear cress) PR
O64698 CYP710A2 Cytochrome P450 710A2 Arabidopsis thaliana (Mouse-ear cress) PR
O64697 CYP710A1 Cytochrome P450 710A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q94IA6 CYP90D1 3-epi-6-deoxocathasterone 23-monooxygenase CYP90D1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC9 CYP72A11 Cytochrome P450 72A11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC8 CYP72A13 Cytochrome P450 72A13 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC6 CYP72A14 Cytochrome P450 72A14 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC5 CYP72A15 Cytochrome P450 72A15 Arabidopsis thaliana (Mouse-ear cress) PR
Q6TBX7 CYP97C1 Carotene epsilon-monooxygenase, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZUX1 CYP94C1 Cytochrome P450 94C1 Arabidopsis thaliana (Mouse-ear cress) PR
Q6EIG3 cyp26b1 Cytochrome P450 26B1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MSLCLVIACM VTSWIFLHRW GQRNKSGPKT WPLVGAAIEQ LTNFDRMHDW LVEYLYNSRT
70 80 90 100 110 120
VVVPMPFTTY TYIADPINVE YVLKTNFSNY PKGETYHSYM EVLLGDGIFN SDGELWRKQR
130 140 150 160 170 180
KTASFEFASK NLRDFSTVVF KEYSLKLFTI LSQASFKEQQ VDMQELLMRM TLDSICKVGF
190 200 210 220 230 240
GVEIGTLAPE LPENHFAKAF DTANIIVTLR FIDPLWKMKK FLNIGSEALL GKSIKVVNDF
250 260 270 280 290 300
TYSVIRRRKA ELLEAQISPT NNNNNNNNKV KHDILSRFIE ISDDPDSKET EKSLRDIVLN
310 320 330 340 350 360
FVIAGRDTTA TTLTWAIYMI MMNENVAEKL YSELQELEKE SAEATNTSLH QYDTEDFNSF
370 380 390 400 410 420
NEKVTEFAGL LNYDSLGKLH YLHAVITETL RLYPAVPQDP KGVLEDDMLP NGTKVKAGGM
430 440 450 460 470 480
VTYVPYSMGR MEYNWGSDAA LFKPERWLKD GVFQNASPFK FTAFQAGPRI CLGKDSAYLQ
490 500 510 520
MKMAMAILCR FYKFHLVPNH PVKYRMMTIL SMAHGLKVTV SRRS