Q9ZUX1

PR
Gene name
CYP94C1
Protein name
Cytochrome P450 94C1
Names
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G27690
EC number
1.14.14.49: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

433-495 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9ZUX1

Entry ID Method Resolution Chain Position Source
AF-Q9ZUX1-F1 Predicted AlphaFoldDB

38 variants for Q9ZUX1

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_11809393_C_A 7 F>L No 1000Genomes
ENSVATH13436368 10 V>I No 1000Genomes
ENSVATH05607500 26 L>F No 1000Genomes
tmp_2_11809503_G_A 44 S>N No 1000Genomes
ENSVATH05607501 48 D>N No 1000Genomes
ENSVATH13436371 119 D>E No 1000Genomes
ENSVATH13436372 128 A>T No 1000Genomes
ENSVATH05607502 142 H>N No 1000Genomes
ENSVATH13436373 142 H>R No 1000Genomes
tmp_2_11809799_G_A 143 E>K No 1000Genomes
ENSVATH01909834 145 V>I No 1000Genomes
ENSVATH14561463 158 T>I No 1000Genomes
tmp_2_11809978_A_T 202 E>D No 1000Genomes
tmp_2_11810031_C_T 220 A>V No 1000Genomes
tmp_2_11810043_T_A 224 L>Q No 1000Genomes
ENSVATH05607508 279 E>A No 1000Genomes
ENSVATH01909837 310 L>I No 1000Genomes
tmp_2_11810344_A_C,G 324 E>D No 1000Genomes
ENSVATH05607509 328 V>L No 1000Genomes
ENSVATH05607510 336 V>D No 1000Genomes
ENSVATH05607511 340 C>S No 1000Genomes
ENSVATH13436386 345 E>Q No 1000Genomes
ENSVATH01909838 346 M>I No 1000Genomes
ENSVATH01909839 370 A>S No 1000Genomes
ENSVATH13436387 375 V>L No 1000Genomes
ENSVATH14561495 376 L>F No 1000Genomes
tmp_2_11810583_C_T 404 P>L No 1000Genomes
ENSVATH13436388 404 P>T No 1000Genomes
tmp_2_11810619_A_T 416 D>V No 1000Genomes
tmp_2_11810774_G_A 468 E>K No 1000Genomes
ENSVATH01909841 470 T>S No 1000Genomes
ENSVATH13436390 473 L>I No 1000Genomes
ENSVATH05607514 475 F>Y No 1000Genomes
tmp_2_11810819_G_A 483 V>I No 1000Genomes
ENSVATH01909842 487 L>F No 1000Genomes
ENSVATH05607515 488 P>L No 1000Genomes
ENSVATH05607516 494 R>W No 1000Genomes
ENSVATH13436392 495 S>N No 1000Genomes

No associated diseases with Q9ZUX1

No regional properties for Q9ZUX1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9ZUX1

Functions

Description
EC Number 1.14.14.49 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Subcellular Localization
  • Membrane ; Single-pass membrane protein
  • Endoplasmic reticulum membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

3 GO annotations of molecular function

Name Definition
alkane 1-monooxygenase activity Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.

1 GO annotations of biological process

Name Definition
response to wounding Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

36 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VYQ5 Cyp318a1 Probable cytochrome P450 318a1 Drosophila melanogaster (Fruit fly) PR
Q9VXY0 Cyp4s3 Probable cytochrome P450 4s3 Drosophila melanogaster (Fruit fly) PR
Q9VMS7 Cyp4ac3 Probable cytochrome P450 4ac3 Drosophila melanogaster (Fruit fly) PR
Q9V559 Cyp4p3 Probable cytochrome P450 4p3 Drosophila melanogaster (Fruit fly) PR
Q9V7G5 Cyp4aa1 Probable cytochrome P450 4aa1 Drosophila melanogaster (Fruit fly) PR
Q9VMS8 Cyp4ac2 Probable cytochrome P450 4ac2 Drosophila melanogaster (Fruit fly) PR
Q9VVN6 Cyp312a1 Probable cytochrome P450 312a1 Drosophila melanogaster (Fruit fly) PR
Q02928 CYP4A11 Cytochrome P450 4A11 Homo sapiens (Human) PR
Q86W10 CYP4Z1 Cytochrome P450 4Z1 Homo sapiens (Human) PR
Q5TCH4 CYP4A22 Cytochrome P450 4A22 Homo sapiens (Human) PR
P13584 CYP4B1 Cytochrome P450 4B1 Homo sapiens (Human) PR
Q6ZWL3 CYP4V2 Cytochrome P450 4V2 Homo sapiens (Human) PR
B6SSW8 CYP714B3 Cytochrome P450 714B3 Zea mays (Maize) PR
O35728 Cyp4a14 Cytochrome P450 4A14 Mus musculus (Mouse) PR
Q91WL5 Cyp4a12a Cytochrome P450 4A12A Mus musculus (Mouse) PR
Q9GJX5 CYP4A21 Taurochenodeoxycholic 6 alpha-hydroxylase Sus scrofa (Pig) PR
Q8SPK1 CYP4A24 Cytochrome P450 4A24 Sus scrofa (Pig) PR
P24464 Cyp4a12 Cytochrome P450 4A12 Rattus norvegicus (Rat) PR
G3V7X8 Cyp26b1 Cytochrome P450 26B1 Rattus norvegicus (Rat) PR
P20816 Cyp4a2 Cytochrome P450 4A2 Rattus norvegicus (Rat) PR
Q05JG2 CYP707A5 Abscisic acid 8'-hydroxylase 1 Oryza sativa subsp japonica (Rice) PR
Q0DS59 CYP714B2 Cytochrome P450 714B2 Oryza sativa subsp japonica (Rice) PR
Q6F4F5 CYP724B1 Cytochrome P450 724B1 Oryza sativa subsp japonica (Rice) PR
Q5KQH7 CYP714D1 Cytochrome P450 714D1 Oryza sativa subsp japonica (Rice) PR
Q9SHG5 CYP72C1 Cytochrome P450 72C1 Arabidopsis thaliana (Mouse-ear cress) PR
O81077 CYP707A2 Abscisic acid 8'-hydroxylase 2 Arabidopsis thaliana (Mouse-ear cress) PR
O64698 CYP710A2 Cytochrome P450 710A2 Arabidopsis thaliana (Mouse-ear cress) PR
O64697 CYP710A1 Cytochrome P450 710A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q94IA6 CYP90D1 3-epi-6-deoxocathasterone 23-monooxygenase CYP90D1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC9 CYP72A11 Cytochrome P450 72A11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC8 CYP72A13 Cytochrome P450 72A13 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC6 CYP72A14 Cytochrome P450 72A14 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUC5 CYP72A15 Cytochrome P450 72A15 Arabidopsis thaliana (Mouse-ear cress) PR
Q6TBX7 CYP97C1 Carotene epsilon-monooxygenase, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9C788 CYP704B1 Cytochrome P450 704B1 Arabidopsis thaliana (Mouse-ear cress) PR
Q6EIG3 cyp26b1 Cytochrome P450 26B1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MLLIISFTIV SFFFIIIFSL FHLLFLQKLR YCNCEICHAY LTSSWKKDFI NLSDWYTHLL
70 80 90 100 110 120
RRSPTSTIKV HVLNSVITAN PSNVEHILKT NFHNYPKGKQ FSVILGDLLG RGIFNSDGDT
130 140 150 160 170 180
WRFQRKLASL ELGSVSVRVF AHEIVKTEIE TRLLPILTSF SDNPGSVLDL QDVFRRFSFD
190 200 210 220 230 240
TISKLSFGFD PDCLRLPFPI SEFAVAFDTA SLLSAKRALA PFPLLWKTKR LLRIGSEKKL
250 260 270 280 290 300
QESINVINRL AGDLIKQRRL TGLMGKNDLI SRFMAVVAED DDEYLRDIVV SFLLAGRDTV
310 320 330 340 350 360
AAGLTGFFWL LTRHPEVENR IREELDRVMG TGFDSVTARC DEMREMDYLH ASLYESMRLF
370 380 390 400 410 420
PPVQFDSKFA LNDDVLSDGT FVNSGTRVTY HAYAMGRMDR IWGPDYEEFK PERWLDNEGK
430 440 450 460 470 480
FRPENPVKYP VFQAGARVCI GKEMAIMEMK SIAVAIIRRF ETRVASPETT ETLRFAPGLT
490
ATVNGGLPVM IQERS