P79102
Gene name |
CYP3A28 |
Protein name |
Cytochrome P450 3A28 |
Names |
CYPIIIA28 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
|
EC number |
1.14.14.1: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P79102
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P79102-F1 | Predicted | AlphaFoldDB |
No variants for P79102
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P79102 | |||||
No associated diseases with P79102
1 regional properties for P79102
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cytochrome P450, conserved site | 435 - 444 | IPR017972 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.14.1 | With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| aromatase activity | Catalysis of the reduction of an aliphatic ring to yield an aromatic ring. |
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| oxidative demethylation | The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate. |
19 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2KIG5 | TBXAS1 | Thromboxane-A synthase | Bos taurus (Bovine) | PR |
| Q9V776 | Cyp317a1 | Probable cytochrome P450 317a1 | Drosophila melanogaster (Fruit fly) | PR |
| Q9VG82 | Cyp9f2 | Probable cytochrome P450 9f2 | Drosophila melanogaster (Fruit fly) | PR |
| Q9V4U7 | Cyp6a14 | Probable cytochrome P450 6a14 | Drosophila melanogaster (Fruit fly) | PR |
| Q9V4U9 | Cyp6a13 | Probable cytochrome P450 6a13 | Drosophila melanogaster (Fruit fly) | PR |
| Q9V773 | Cyp6a20 | Probable cytochrome P450 6a20 | Drosophila melanogaster (Fruit fly) | PR |
| P24557 | TBXAS1 | Thromboxane-A synthase | Homo sapiens (Human) | PR |
| P36423 | Tbxas1 | Thromboxane-A synthase | Mus musculus (Mouse) | PR |
| Q5KQH7 | CYP714D1 | Cytochrome P450 714D1 | Oryza sativa subsp japonica (Rice) | PR |
| Q27513 | cyp-13A4 | Putative cytochrome P450 CYP13A4 | Caenorhabditis elegans | PR |
| Q27519 | cyp-13A7 | Putative cytochrome P450 CYP13A7 | Caenorhabditis elegans | PR |
| Q27518 | cyp-13A2 | Putative cytochrome P450 CYP13A2 | Caenorhabditis elegans | PR |
| Q09653 | cyp-13A10 | Putative cytochrome P450 CYP13A10 | Caenorhabditis elegans | PR |
| B9DFU2 | CYP711A1 | Cytochrome P450 711A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SHG5 | CYP72C1 | Cytochrome P450 72C1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUC9 | CYP72A11 | Cytochrome P450 72A11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUC8 | CYP72A13 | Cytochrome P450 72A13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUC6 | CYP72A14 | Cytochrome P450 72A14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUC5 | CYP72A15 | Cytochrome P450 72A15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MELIPSFSME | TWVLLATSLV | LLYIYGTYSY | GLFKKLGIPG | PRPVPYFGST | MAYHKGIPEF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DNQCFKKYGK | MWGFYEGRQP | MLAITDPDII | KTVLVKECYS | VFTNRRIFGP | MGIMKYAISL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AWDEQWKRIR | TLLSPAFTSG | KLKEMFPIIG | QYGDMLVRNL | RKEAEKGNPV | NMKDMFGAYS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MDVITGTAFG | VNIDSLNNPH | DPFVEHSKNL | LRFRPFDPFI | LSIILFPFLN | PVFEILNITL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FPKSTVDFFT | KSVKKIKESR | LTDKQMNRVD | LLQLMINSQN | SKEIDNHKAL | SDIELVAQST |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IFIFGGYETT | SSTLSFIIYE | LTTHPHVQQK | LQEEIDATFP | NKAPPTYDAL | VQMEYLDMVV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NETLRMFPIA | GRLERVCKKD | VEIHGVTIPK | GTTVLVPLFV | LHNNPELWPE | PEEFRPERFS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KNNKDSINPY | VYLPFGTGPR | NCLGMRFAIM | NIKLALVRIL | QNFSFKPCKE | TQIPLKLYTQ |
| 490 | 500 | ||||
| GLTQPEQPVI | LKVVPRGLGP | QVEPDFL |