Q27518

PR
Gene name
cyp-13A2 (cyp13a2, T10B9.7)
Protein name
Putative cytochrome P450 CYP13A2
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_T10B9.7
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

101-185 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q27518

Entry ID Method Resolution Chain Position Source
AF-Q27518-F1 Predicted AlphaFoldDB

No variants for Q27518

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q27518

No associated diseases with Q27518

1 regional properties for Q27518

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 429 - 438 IPR017972

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

16 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2KIG5 TBXAS1 Thromboxane-A synthase Bos taurus (Bovine) PR
P79102 CYP3A28 Cytochrome P450 3A28 Bos taurus (Bovine) PR
Q9V4U7 Cyp6a14 Probable cytochrome P450 6a14 Drosophila melanogaster (Fruit fly) PR
Q9V773 Cyp6a20 Probable cytochrome P450 6a20 Drosophila melanogaster (Fruit fly) PR
Q9V4U9 Cyp6a13 Probable cytochrome P450 6a13 Drosophila melanogaster (Fruit fly) PR
Q9VG82 Cyp9f2 Probable cytochrome P450 9f2 Drosophila melanogaster (Fruit fly) PR
P24557 TBXAS1 Thromboxane-A synthase Homo sapiens (Human) PR
P36423 Tbxas1 Thromboxane-A synthase Mus musculus (Mouse) PR
Q6YV88 CYP71Z7 Ent-cassadiene hydroxylase Oryza sativa subsp japonica (Rice) PR
Q5KQH7 CYP714D1 Cytochrome P450 714D1 Oryza sativa subsp japonica (Rice) PR
Q0DS59 CYP714B2 Cytochrome P450 714B2 Oryza sativa subsp japonica (Rice) PR
A3A871 CYP71Z6 Ent-isokaurene C2/C3-hydroxylase Oryza sativa subsp japonica (Rice) PR
Q7X7X4 CYP99A2 Cytochrome P450 99A2 Oryza sativa subsp japonica (Rice) PR
Q09653 cyp-13A10 Putative cytochrome P450 CYP13A10 Caenorhabditis elegans PR
Q27513 cyp-13A4 Putative cytochrome P450 CYP13A4 Caenorhabditis elegans PR
Q27519 cyp-13A7 Putative cytochrome P450 CYP13A7 Caenorhabditis elegans PR
10 20 30 40 50 60
MSLGFVLAVT FSIFLGILTY YLWIWTYWMR KGVKGPRGRP FVGVLDVLLE HETPGLIKLG
70 80 90 100 110 120
EWTKKYGKVY GYTDGTQRTL VVADPAMVHE IFVKQFDNFY GRKLNPIQGN PEKEQRVHLL
130 140 150 160 170 180
AAQGYRWKRL RTISSQSFSN ASLKKMKRTV EDSALELLRH IEKQTAGGEQ IDMLRFYQEY
190 200 210 220 230 240
TMDVIGRFAM GQTDSMMFKN PIVNVVREIF CGSRKNLMLI CQVFPPIGQF IRDLTFKFPR
250 260 270 280 290 300
IPAFKLYSIM QDVVAARIAQ REREKGAESG EPQDFIDLFL DARSDDVDFS AEAREDFSKR
310 320 330 340 350 360
NLKITKELSA DEVVGQCFLF LIGGFDTTAL SLSYVTYLLA VNPKIQEKVI EEIAREFGTS
370 380 390 400 410 420
EVEFEKLGRL KYMDCVIKEA LRLYPLASIS NSRKCMKTTT VNGVKIEAGV YVQMDTWSLH
430 440 450 460 470 480
YDPELWGEDV KEFKPERWST DEPLEHKGAY LPFGLGPRQC IGMRLAIMEQ KILLTHLLKN
490 500 510
YTFETGNKTR IPLKLVGSAT TSPEDVFVHL RPRIW