Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9Z2I7

Entry ID Method Resolution Chain Position Source
AF-Q9Z2I7-F1 Predicted AlphaFoldDB

No variants for Q9Z2I7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9Z2I7

No associated diseases with Q9Z2I7

1 regional properties for Q9Z2I7

Type Name Position InterPro Accession
domain Major facilitator superfamily domain 86 - 513 IPR020846

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
anchoring junction A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
synaptic vesicle A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
synaptic vesicle membrane The lipid bilayer surrounding a synaptic vesicle.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

20 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q17QN9 SLC22A16 Solute carrier family 22 member 16 Bos taurus (Bovine) PR
Q1JP63 SVOP Synaptic vesicle 2-related protein Bos taurus (Bovine) PR
Q9H015 SLC22A4 Solute carrier family 22 member 4 Homo sapiens (Human) PR
Q7L1I2 SV2B Synaptic vesicle glycoprotein 2B Homo sapiens (Human) PR
Q496J9 SV2C Synaptic vesicle glycoprotein 2C Homo sapiens (Human) PR
A6NKX4 SLC22A31 Putative solute carrier family 22 member 31 Homo sapiens (Human) PR
Q8N434 SVOPL Putative transporter SVOPL Homo sapiens (Human) PR
Q8N4V2 SVOP Synaptic vesicle 2-related protein Homo sapiens (Human) PR
Q9Z0E8 Slc22a5 Solute carrier family 22 member 5 Mus musculus (Mouse) PR
Q9Z306 Slc22a4 Solute carrier family 22 member 4 Mus musculus (Mouse) PR
Q9D9E0 Slc22a17 Solute carrier family 22 member 17 Mus musculus (Mouse) PR
Q497L8 Slc22a16 Solute carrier family 22 member 16 Mus musculus (Mouse) PR
Q69ZS6 Sv2c Synaptic vesicle glycoprotein 2C Mus musculus (Mouse) PR
Q6PDF3 Svopl Putative transporter SVOPL Mus musculus (Mouse) PR
Q8BFT9 Svop Synaptic vesicle 2-related protein Mus musculus (Mouse) PR
Q70BM6 SLC22A8 Organic anion transporter 3 Sus scrofa (Pig) PR
Q9Z2I6 Sv2c Synaptic vesicle glycoprotein 2C Rattus norvegicus (Rat) PR
Q9R141 Slc22a4 Solute carrier family 22 member 4 Rattus norvegicus (Rat) PR
Q7Z118 B0361.11 Putative transporter B0361.11 Caenorhabditis elegans PR
Q1LVS8 svopl Putative transporter SVOPL Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MEEDLFQLRQ LPVVKFRRTG ESARSEDDAA SGEHDVQIEG VRVGLEAVEL DDGAAVPKEF
70 80 90 100 110 120
ANPTDDTFMV EDAVEAIGFG RFQWKLSVLT GLAWMADAME MMILSILAPQ LHCEWRLPSW
130 140 150 160 170 180
QVALLTSVVF IGMMSSSTLW GNISDQYGRK TGLKISVFWT LYYGILSAFA PVYSWILVLR
190 200 210 220 230 240
GLVGFGIGGV PQSVTLYAEF LPMKARAKCI LLIEVFWAIG TVFEVLLAVF VMPSLGWRWL
250 260 270 280 290 300
LLLSAAPLLV FAVLCFWLPE SARYDVLSGN QEKAIATLKR IATENGAPMP LGKLIISRQE
310 320 330 340 350 360
DRGKMRDLFT PHFRWTTLLL WFIWFSNAFS YYGLVLLTTE LFQAGDVCSI SSRKKAVEAK
370 380 390 400 410 420
CSLACEYLSK EDYMDLLWTT LSEFPGVLVT LWVIDRLGRK KTMALCFVIF SLCSLLLFIC
430 440 450 460 470 480
IGRNVLTLLL FIARAFISGG FQAAYVYTPE VYPTATRALG LGTCSGMARV GALITPFIAQ
490 500 510 520 530 540
VMLESSVYLT LAVYSGCCLL AALASCFLPI ETKGRALQES SHREWGQEMV GRGTNSTGVP
RSNSGSQE