AiPD: Autoinhibited Protein Database

Gene name	Svop
Protein name	Synaptic vesicle 2-related protein
Names	SV2-related protein
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:68666
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-75 (Predicted disordered autoinhibitory region) PR

1-75 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8BFT9-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3388782640	30	A>D	No	EVA
rs3388782178	34	H>R	No	EVA
rs3388776967	66	D>G	No	EVA
rs3388773467	73	A>G	No	EVA
rs3388767904	110	Q>H	No	EVA
rs3388781602	110	Q>R	No	EVA
rs3388773505	113	C>R	No	EVA
rs3388776961	116	R>*	No	EVA
rs3388770662	137	S>F	No	EVA
rs3388770724	152	G>R	No	EVA
rs3388763006	232	M>T	No	EVA
rs3388779713	305	M>L	No	EVA
rs3388778664	473	L>F	No	EVA
rs3388785804	515	R>*	No	EVA

Type	Name	Position	InterPro Accession
domain	Major facilitator superfamily domain	86 - 513	IPR020846

		Description
EC Number
Subcellular Localization	Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
anchoring junction	A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
synaptic vesicle	A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
synaptic vesicle membrane	The lipid bilayer surrounding a synaptic vesicle.

Name	Definition
transmembrane transporter activity	Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

Name	Definition
No GO annotations for biological process

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q17QN9	SLC22A16	Solute carrier family 22 member 16	Bos taurus (Bovine)	PR
Q1JP63	SVOP	Synaptic vesicle 2-related protein	Bos taurus (Bovine)	PR
Q9H015	SLC22A4	Solute carrier family 22 member 4	Homo sapiens (Human)	PR
Q7L1I2	SV2B	Synaptic vesicle glycoprotein 2B	Homo sapiens (Human)	PR
Q496J9	SV2C	Synaptic vesicle glycoprotein 2C	Homo sapiens (Human)	PR
A6NKX4	SLC22A31	Putative solute carrier family 22 member 31	Homo sapiens (Human)	PR
Q8N434	SVOPL	Putative transporter SVOPL	Homo sapiens (Human)	PR
Q8N4V2	SVOP	Synaptic vesicle 2-related protein	Homo sapiens (Human)	PR
Q69ZS6	Sv2c	Synaptic vesicle glycoprotein 2C	Mus musculus (Mouse)	PR
Q9Z0E8	Slc22a5	Solute carrier family 22 member 5	Mus musculus (Mouse)	PR
Q9Z306	Slc22a4	Solute carrier family 22 member 4	Mus musculus (Mouse)	PR
Q9D9E0	Slc22a17	Solute carrier family 22 member 17	Mus musculus (Mouse)	PR
Q497L8	Slc22a16	Solute carrier family 22 member 16	Mus musculus (Mouse)	PR
Q6PDF3	Svopl	Putative transporter SVOPL	Mus musculus (Mouse)	PR
Q70BM6	SLC22A8	Organic anion transporter 3	Sus scrofa (Pig)	PR
Q9Z2I6	Sv2c	Synaptic vesicle glycoprotein 2C	Rattus norvegicus (Rat)	PR
Q9R141	Slc22a4	Solute carrier family 22 member 4	Rattus norvegicus (Rat)	PR
Q9Z2I7	Svop	Synaptic vesicle 2-related protein	Rattus norvegicus (Rat)	PR
Q7Z118	B0361.11	Putative transporter B0361.11	Caenorhabditis elegans	PR
Q1LVS8	svopl	Putative transporter SVOPL	Danio rerio (Zebrafish) (Brachydanio rerio)	PR