Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7Z118

Entry ID Method Resolution Chain Position Source
AF-Q7Z118-F1 Predicted AlphaFoldDB

No variants for Q7Z118

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7Z118

No associated diseases with Q7Z118

2 regional properties for Q7Z118

Type Name Position InterPro Accession
conserved_site Sugar transporter, conserved site 164 - 181 IPR005829
domain Major facilitator superfamily domain 53 - 511 IPR020846

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
carbohydrate transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.

17 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q17QN9 SLC22A16 Solute carrier family 22 member 16 Bos taurus (Bovine) PR
Q1JP63 SVOP Synaptic vesicle 2-related protein Bos taurus (Bovine) PR
Q9H015 SLC22A4 Solute carrier family 22 member 4 Homo sapiens (Human) PR
Q7L1I2 SV2B Synaptic vesicle glycoprotein 2B Homo sapiens (Human) PR
Q496J9 SV2C Synaptic vesicle glycoprotein 2C Homo sapiens (Human) PR
Q8N4V2 SVOP Synaptic vesicle 2-related protein Homo sapiens (Human) PR
A6NKX4 SLC22A31 Putative solute carrier family 22 member 31 Homo sapiens (Human) PR
Q9Z0E8 Slc22a5 Solute carrier family 22 member 5 Mus musculus (Mouse) PR
Q9Z306 Slc22a4 Solute carrier family 22 member 4 Mus musculus (Mouse) PR
Q9D9E0 Slc22a17 Solute carrier family 22 member 17 Mus musculus (Mouse) PR
Q8BFT9 Svop Synaptic vesicle 2-related protein Mus musculus (Mouse) PR
Q497L8 Slc22a16 Solute carrier family 22 member 16 Mus musculus (Mouse) PR
Q69ZS6 Sv2c Synaptic vesicle glycoprotein 2C Mus musculus (Mouse) PR
Q70BM6 SLC22A8 Organic anion transporter 3 Sus scrofa (Pig) PR
Q9Z2I7 Svop Synaptic vesicle 2-related protein Rattus norvegicus (Rat) PR
Q9Z2I6 Sv2c Synaptic vesicle glycoprotein 2C Rattus norvegicus (Rat) PR
Q9R141 Slc22a4 Solute carrier family 22 member 4 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MSISRRSYEQ FDEMKSENQE NNSKKKSSER LKKLDPDKFV EAYGAYGKYQ IFTYVLVQTL
70 80 90 100 110 120
NFFYSSSMYI MSFVQLNLEK QCEYKNETIP ISETCQIETE SSKAFGNLNG EYCGIAENTL
130 140 150 160 170 180
VNVTNQKAST NLLVDFDLSC SHWFFQEFGL TIFTIGAVIA VPFMSMLADR YGRKPIIVTT
190 200 210 220 230 240
AILAFLANMA ASFSPNFAIF LILRAFIGAC SDSYLSVASV ATCEYLSEKA RAWITVVYNV
250 260 270 280 290 300
AWSLGMVWTL LVTLMTDDWR WRYFIVSLPG VYGFALWYFL PESPHWLITK NKTEKLKKYI
310 320 330 340 350 360
KTANRVNNVS PEFNDCQQSS HHEEKHESFK ALLGSKKLIW LLFANGFIEM VISLVYFAIS
370 380 390 400 410 420
FMSVELGGDQ VQAFLYSSLI EIPAGLAVIP LMMKMGRKMI VIWCLVFQTL ALIGVTVFLD
430 440 450 460 470 480
SYEFKLVIML VAKVMATIIY SVHPIWATEQ FPTSVRSLCF SLMNIPQSMG IIMSPYVKHI
490 500 510 520 530 540
VMSPNWIPFV VIALFSFISA TLAFMLHETK NKKLPTDIES LSYPSETNDL SAYRRSKSSS
550 560 570
SSVSALSKTS VRSKKTLSSE SVSKKLDTVN FSDKEYRI