Q1JP63
PR
Gene name |
SVOP |
Protein name |
Synaptic vesicle 2-related protein |
Names |
SV2-related protein |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:510256 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q1JP63
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q1JP63-F1 | Predicted | AlphaFoldDB |
93 variants for Q1JP63
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs456698934 | 2 | E>D | No | EVA | |
| rs475556955 | 4 | D>E | No | EVA | |
| rs442500677 | 6 | F>C | No | EVA | |
| rs460956439 | 8 | L>F | No | EVA | |
| rs465997220 | 13 | V>E | No | EVA | |
| rs380057125 | 17 | R>S | No | EVA | |
| rs456472562 | 27 | D>Y | No | EVA | |
| rs1115342490 | 32 | G>E | No | EVA | |
| rs433014991 | 41 | V>G | No | EVA | |
| rs451462661 | 46 | E>A | No | EVA | |
| rs470325906 | 50 | L>V | No | EVA | |
| rs210867117 | 65 | D>E | No | EVA | |
| rs478752722 | 97 | D>A | No | EVA | |
| rs445612931 | 97 | D>E | No | EVA | |
| rs463943346 | 100 | E>G | No | EVA | |
| rs482744681 | 102 | M>L | No | EVA | |
| rs449855619 | 103 | I>M | No | EVA | |
| rs468482430 | 104 | L>P | No | EVA | |
| rs435407357 | 115 | W>* | No | EVA | |
| rs447437890 | 117 | L>R | No | EVA | |
| rs466263968 | 118 | P>A | No | EVA | |
| rs466263968 | 118 | P>S | No | EVA | |
| rs433216540 | 119 | S>R | No | EVA | |
| rs451727118 | 120 | W>R | No | EVA | |
| rs476575843 | 121 | Q>E | No | EVA | |
| rs437507003 | 121 | Q>P | No | EVA | |
| rs456003530 | 122 | V>G | No | EVA | |
| rs441440391 | 123 | A>G | No | EVA | |
| rs441440391 | 123 | A>V | No | EVA | |
| rs459905664 | 124 | L>V | No | EVA | |
| rs472105449 | 124 | L>W | No | EVA | |
| rs439232105 | 126 | T>A | No | EVA | |
| rs457590604 | 126 | T>N | No | EVA | |
| rs449569974 | 127 | S>P | No | EVA | |
| rs135636711 | 229 | V>G | No | EVA | |
| rs435567545 | 261 | S>R | No | EVA | |
| rs466423069 | 264 | Y>D | No | EVA | |
| rs451768432 | 291 | L>R | No | EVA | |
| rs452761783 | 315 | W>* | No | EVA | |
| rs455134417 | 395 | D>G | No | EVA | |
| rs466250199 | 404 | A>T | No | EVA | |
| rs473677904 | 413 | C>* | No | EVA | |
| rs464813211 | 424 | N>I | No | EVA | |
| rs438195256 | 424 | N>K | No | EVA | |
| rs464813211 | 424 | N>T | No | EVA | |
| rs475566609 | 425 | M>I | No | EVA | |
| rs456641479 | 425 | M>L | No | EVA | |
| rs454468098 | 427 | T>P | No | EVA | |
| rs452301738 | 429 | L>F | No | EVA | |
| rs470672589 | 430 | L>P | No | EVA | |
| rs481244113 | 432 | I>F | No | EVA | |
| rs442129321 | 433 | A>S | No | EVA | |
| rs460632963 | 434 | R>K | No | EVA | |
| rs446019799 | 435 | A>E | No | EVA | |
| rs483321902 | 437 | I>F | No | EVA | |
| rs450341109 | 437 | I>S | No | EVA | |
| rs468790967 | 438 | S>F | No | EVA | |
| rs435782246 | 439 | G>* | No | EVA | |
| rs451965522 | 441 | F>L | No | EVA | |
| rs433569255 | 441 | F>S | No | EVA | |
| rs470587904 | 442 | Q>H | No | EVA | |
| rs444327715 | 444 | A>P | No | EVA | |
| rs474853947 | 446 | V>A | No | EVA | |
| rs456405985 | 446 | V>F | No | EVA | |
| rs476707269 | 451 | V>A | No | EVA | |
| rs109193370 | 452 | Y>S | No | EVA | |
| rs473989901 | 460 | G>C | No | EVA | |
| rs441510889 | 466 | G>A | No | EVA | |
| rs459871576 | 467 | M>L | No | EVA | |
| rs478210650 | 468 | A>E | No | EVA | |
| rs445359656 | 469 | R>M | No | EVA | |
| rs457779647 | 469 | R>S | No | EVA | |
| rs449678973 | 470 | V>G | No | EVA | |
| rs482741500 | 470 | V>L | No | EVA | |
| rs447586060 | 471 | G>A | No | EVA | |
| rs435168431 | 471 | G>R | No | EVA | |
| rs466025376 | 472 | A>P | No | EVA | |
| rs451455107 | 474 | I>T | No | EVA | |
| rs469947578 | 475 | T>P | No | EVA | |
| rs474054960 | 480 | Q>E | No | EVA | |
| rs473081639 | 481 | V>A | No | EVA | |
| rs440240383 | 483 | L>R | No | EVA | |
| rs458713898 | 484 | E>* | No | EVA | |
| rs477229721 | 484 | E>A | No | EVA | |
| rs477229721 | 484 | E>G | No | EVA | |
| rs463010774 | 496 | G>S | No | EVA | |
| rs481420431 | 498 | C>W | No | EVA | |
| rs448452697 | 508 | L>F | No | EVA | |
| rs467291969 | 511 | E>K | No | EVA | |
| rs479336528 | 520 | S>A | No | EVA | |
| rs479336528 | 520 | S>P | No | EVA | |
| rs446310981 | 525 | W>G | No | EVA | |
| rs464767164 | 528 | E>A | No | EVA |
No associated diseases with Q1JP63
1 regional properties for Q1JP63
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 86 - 513 | IPR020846 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| anchoring junction | A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| synaptic vesicle membrane | The lipid bilayer surrounding a synaptic vesicle. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
20 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q17QN9 | SLC22A16 | Solute carrier family 22 member 16 | Bos taurus (Bovine) | PR |
| Q9H015 | SLC22A4 | Solute carrier family 22 member 4 | Homo sapiens (Human) | PR |
| Q7L1I2 | SV2B | Synaptic vesicle glycoprotein 2B | Homo sapiens (Human) | PR |
| Q496J9 | SV2C | Synaptic vesicle glycoprotein 2C | Homo sapiens (Human) | PR |
| A6NKX4 | SLC22A31 | Putative solute carrier family 22 member 31 | Homo sapiens (Human) | PR |
| Q8N434 | SVOPL | Putative transporter SVOPL | Homo sapiens (Human) | PR |
| Q8N4V2 | SVOP | Synaptic vesicle 2-related protein | Homo sapiens (Human) | PR |
| Q9Z0E8 | Slc22a5 | Solute carrier family 22 member 5 | Mus musculus (Mouse) | PR |
| Q9Z306 | Slc22a4 | Solute carrier family 22 member 4 | Mus musculus (Mouse) | PR |
| Q9D9E0 | Slc22a17 | Solute carrier family 22 member 17 | Mus musculus (Mouse) | PR |
| Q497L8 | Slc22a16 | Solute carrier family 22 member 16 | Mus musculus (Mouse) | PR |
| Q69ZS6 | Sv2c | Synaptic vesicle glycoprotein 2C | Mus musculus (Mouse) | PR |
| Q6PDF3 | Svopl | Putative transporter SVOPL | Mus musculus (Mouse) | PR |
| Q8BFT9 | Svop | Synaptic vesicle 2-related protein | Mus musculus (Mouse) | PR |
| Q70BM6 | SLC22A8 | Organic anion transporter 3 | Sus scrofa (Pig) | PR |
| Q9Z2I6 | Sv2c | Synaptic vesicle glycoprotein 2C | Rattus norvegicus (Rat) | PR |
| Q9R141 | Slc22a4 | Solute carrier family 22 member 4 | Rattus norvegicus (Rat) | PR |
| Q9Z2I7 | Svop | Synaptic vesicle 2-related protein | Rattus norvegicus (Rat) | PR |
| Q7Z118 | B0361.11 | Putative transporter B0361.11 | Caenorhabditis elegans | PR |
| Q1LVS8 | svopl | Putative transporter SVOPL | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEEDLFQLRQ | LPVVKFRRTG | ESARSEDDTA | SGEHEVQIEG | VRAGLEAVEL | DDGAAVPKEF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ANPTDDTFMV | EDAVEAIGFG | KFQWKLSVLT | GLAWMADAME | MMILSILAPQ | LHCEWRLPSW |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QVALLTSVVF | VGMMSSSTLW | GNISDQYGRK | TGLKISVLWT | LYYGILSAFA | PVYSWILVLR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GLVGFGIGGV | PQSVTLYAEF | LPMKARAKCI | LLIEVFWAIG | TVFEVVLAVF | VMPSLGWRWL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LILSAVPLLL | FAVLCFWLPE | SARYDVLSGN | QEKAIATLKR | IATENGAPMP | LGKLIISRQE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DRGKMRDLFT | PHFRWTTLLL | WFIWFSNAFS | YYGLVLLTTE | LFQAGDVCSI | SSRKKAVEAK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| CSLACEYLSE | EDYMDLLWTT | LSEFPGVLVT | LWIIDRLGRK | KTMALCFVVF | SFCSLLLFIC |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VGRNMLTLLL | FIARAFISGG | FQAAYVYTPE | VYPTATRALG | LGTCSGMARV | GALITPFIAQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VMLESSVYLT | LAVYSGCCLL | AALASCFLPI | ETKGRGLQES | SHREWGQEMV | GRGAHGTGVA |
| RSNSGSQE |