Q6PDF3
Gene name |
Svopl |
Protein name |
Putative transporter SVOPL |
Names |
SVOP-like protein |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:320590 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6PDF3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6PDF3-F1 | Predicted | AlphaFoldDB |
33 variants for Q6PDF3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs48835068 | 45 | R>H | No | EVA | |
| rs3388821514 | 49 | A>T | No | EVA | |
| rs3388825052 | 56 | S>N | No | EVA | |
| rs3395895196 | 61 | E>N | No | EVA | |
| rs3395895196 | 61 | E>S | No | EVA | |
| rs3396402904 | 64 | E>I | No | EVA | |
| rs3396706070 | 64 | E>K | No | EVA | |
| rs3388809799 | 104 | F>L | No | EVA | |
| rs3388821282 | 112 | G>V | No | EVA | |
| rs3388824414 | 127 | F>Y | No | EVA | |
| rs1133438117 | 136 | S>P | No | EVA | |
| rs3388822702 | 137 | Y>H | No | EVA | |
| rs3388806532 | 140 | F>V | No | EVA | |
| rs3388815884 | 198 | T>I | No | EVA | |
| rs3388806516 | 215 | L>I | No | EVA | |
| rs3388809820 | 232 | T>I | No | EVA | |
| rs3396491360 | 234 | N>H | No | EVA | |
| rs3388817869 | 257 | Q>* | No | EVA | |
| rs46602372 | 257 | Q>R | No | EVA | |
| rs3388812808 | 260 | E>D | No | EVA | |
| rs3388817813 | 282 | L>I | No | EVA | |
| rs3388812822 | 286 | I>N | No | EVA | |
| rs3388806491 | 322 | V>SDG* | No | EVA | |
| rs3396241625 | 331 | E>D | No | EVA | |
| rs3396705347 | 332 | G>A | No | EVA | |
| rs3396705346 | 332 | G>R | No | EVA | |
| rs30279318 | 340 | I>M | No | EVA | |
| rs3396622530 | 389 | L>H | No | EVA | |
| rs3388821301 | 398 | G>C | No | EVA | |
| rs3388825106 | 409 | L>P | No | EVA | |
| rs3388822665 | 410 | V>A | No | EVA | |
| rs3388802274 | 480 | T>I | No | EVA | |
| rs3388824439 | 487 | G>V | No | EVA |
No associated diseases with Q6PDF3
1 regional properties for Q6PDF3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 50 - 486 | IPR020846 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q1JP63 | SVOP | Synaptic vesicle 2-related protein | Bos taurus (Bovine) | PR |
| Q8N4V2 | SVOP | Synaptic vesicle 2-related protein | Homo sapiens (Human) | PR |
| Q8N434 | SVOPL | Putative transporter SVOPL | Homo sapiens (Human) | PR |
| Q9Z0E8 | Slc22a5 | Solute carrier family 22 member 5 | Mus musculus (Mouse) | PR |
| Q9Z306 | Slc22a4 | Solute carrier family 22 member 4 | Mus musculus (Mouse) | PR |
| Q9D9E0 | Slc22a17 | Solute carrier family 22 member 17 | Mus musculus (Mouse) | PR |
| Q497L8 | Slc22a16 | Solute carrier family 22 member 16 | Mus musculus (Mouse) | PR |
| Q8BFT9 | Svop | Synaptic vesicle 2-related protein | Mus musculus (Mouse) | PR |
| Q9Z2I7 | Svop | Synaptic vesicle 2-related protein | Rattus norvegicus (Rat) | PR |
| Q1LVS8 | svopl | Putative transporter SVOPL | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAKQTEPVT | IISLRKLSQA | APEPQQKETK | TFTVEDAVET | IGFGRFHIAL | FLIMGSTGVV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EAMEIMLIAV | VSPVIRCEWQ | LENWQVAFVT | TMVFFGYMVS | SILFGLLADR | YGRWKILLLS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FLWGAYFSLL | TSFSPSYIWF | VFLRTMVGCG | VSGHAQGLII | KTEFLPTKYR | GYMLPLSQVF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WLAGSLLIIS | MASVVIPTIG | WRWLIRIASI | PGIILIMAFK | FIPESARFNV | STGNTQAALN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TLESIAKMNR | SVMPEGQLVE | PILEKRGRFA | DLLDSKYLRT | TLQIWIIWLG | ISFAYYGVIL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ASAELLERDL | VCGSKSESEP | EVVETTGDSG | EGLSPCYCHI | FAPSDYRTMI | ISTLGEIALN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PLNILGINFL | GRRLSLSITM | GCTALFFLLL | NICTSSAGLI | GFLFMLRALV | AANFNTIYIY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TAEVYPTPMR | AIGMGTSGSL | CRIGAMVAPF | ISQVLMSASF | LGALCLFSSV | CVVCAISAFT |
| 490 | |||||
| LPIETKGRAL | QQIK |