A6NKX4

PR
Gene name
SLC22A31
Protein name
Putative solute carrier family 22 member 31
Names
Species
Homo sapiens (Human)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

499-558 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6NKX4

Entry ID Method Resolution Chain Position Source
AF-A6NKX4-F1 Predicted AlphaFoldDB

No variants for A6NKX4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6NKX4

No associated diseases with A6NKX4

1 regional properties for A6NKX4

Type Name Position InterPro Accession
domain Major facilitator superfamily domain 81 - 510 IPR020846

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

18 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q17QN9 SLC22A16 Solute carrier family 22 member 16 Bos taurus (Bovine) PR
Q1JP63 SVOP Synaptic vesicle 2-related protein Bos taurus (Bovine) PR
Q7L1I2 SV2B Synaptic vesicle glycoprotein 2B Homo sapiens (Human) PR
Q496J9 SV2C Synaptic vesicle glycoprotein 2C Homo sapiens (Human) PR
Q8N4V2 SVOP Synaptic vesicle 2-related protein Homo sapiens (Human) PR
Q9H015 SLC22A4 Solute carrier family 22 member 4 Homo sapiens (Human) PR
Q8N434 SVOPL Putative transporter SVOPL Homo sapiens (Human) PR
Q9Z0E8 Slc22a5 Solute carrier family 22 member 5 Mus musculus (Mouse) PR
Q9Z306 Slc22a4 Solute carrier family 22 member 4 Mus musculus (Mouse) PR
Q9D9E0 Slc22a17 Solute carrier family 22 member 17 Mus musculus (Mouse) PR
Q8BFT9 Svop Synaptic vesicle 2-related protein Mus musculus (Mouse) PR
Q497L8 Slc22a16 Solute carrier family 22 member 16 Mus musculus (Mouse) PR
Q69ZS6 Sv2c Synaptic vesicle glycoprotein 2C Mus musculus (Mouse) PR
Q70BM6 SLC22A8 Organic anion transporter 3 Sus scrofa (Pig) PR
Q9Z2I7 Svop Synaptic vesicle 2-related protein Rattus norvegicus (Rat) PR
Q9Z2I6 Sv2c Synaptic vesicle glycoprotein 2C Rattus norvegicus (Rat) PR
Q9R141 Slc22a4 Solute carrier family 22 member 4 Rattus norvegicus (Rat) PR
Q7Z118 B0361.11 Putative transporter B0361.11 Caenorhabditis elegans PR
10 20 30 40 50 60
MEQEARVLRA AGGFGRARRL LASASWVPCI VLGLVLSSEE LLTAQPAPHC RPDPTLLPPA
70 80 90 100 110 120
LRALRGPALL DAAIPRLGPT RAPAEALGVL SPSYLAPLTR APRPSSWASC SGAAAGPTWN
130 140 150 160 170 180
LVCGDGWKVP LEQVSHLLGW LLGCVILGAG CDRFGRRAVF VASLVLTTGL GASEALAASF
190 200 210 220 230 240
PTLLVLRLLH GGTLAGALLA LYLARLELCD PPHRLAFSMG AGLFSVVGTL LLPGLAALVQ
250 260 270 280 290 300
DWRLLQGLGA LMSGLLLLFW GFPALFPESP CWLLATGQVA RARKILWRFA EASGVGPGDS
310 320 330 340 350 360
SLEENSLATE LTMLSARSPQ PRYHSPLGLL RTRVTWRNGL ILGFSSLVGG GIRASFRRSL
370 380 390 400 410 420
APQVPTFYLP YFLEAGLEAA ALVFLLLTAD CCGRRPVLLL GTMVTGLASL LLLAGAQYLP
430 440 450 460 470 480
GWTVLFLSVL GLLASRAVSA LSSLFAAEVF PTVIRGAGLG LVLGAGFLGQ AAGPLDTLHG
490 500 510 520 530 540
RQGFFLQQVV FASLAVLALL CVLLLPESRS RGLPQSLQDA DRLRRSPLLR GRPRQDHLPL
550
LPPSNSYWAG HTPEQH