Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9SUU1

Entry ID Method Resolution Chain Position Source
AF-Q9SUU1-F1 Predicted AlphaFoldDB

44 variants for Q9SUU1

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06812898 13 N>K No 1000Genomes
tmp_4_15688762_C_T 17 G>E No 1000Genomes
ENSVATH02950968 27 L>F No 1000Genomes
ENSVATH14327066 28 A>P No 1000Genomes
tmp_4_15688626_C_A 35 R>S No 1000Genomes
ENSVATH14327065 41 L>I No 1000Genomes
tmp_4_15688259_A_T 127 W>R No 1000Genomes
ENSVATH06812892 160 G>E No 1000Genomes
tmp_4_15688061_C_A 161 M>I No 1000Genomes
ENSVATH12351995 184 S>Y No 1000Genomes
tmp_4_15687876_A_G 194 F>S No 1000Genomes
ENSVATH06812888 215 A>T No 1000Genomes
tmp_4_15687797_C_G 220 R>S No 1000Genomes
ENSVATH00548443 235 I>T No 1000Genomes
ENSVATH06812883 244 L>V No 1000Genomes
tmp_4_15687642_C_T 245 V>M No 1000Genomes
ENSVATH06812882 274 S>P No 1000Genomes
tmp_4_15687527_A_C 283 V>G No 1000Genomes
ENSVATH06812879 296 A>S No 1000Genomes
ENSVATH06812878 296 A>V No 1000Genomes
ENSVATH06812876 297 A>S No 1000Genomes
tmp_4_15687302_T_G 328 N>T No 1000Genomes
tmp_4_15687097_T_C 366 K>R No 1000Genomes
ENSVATH14327021 385 K>E No 1000Genomes
ENSVATH06812870 388 M>I No 1000Genomes
ENSVATH02950951 404 V>M No 1000Genomes
tmp_4_15686741_C_T 426 E>K No 1000Genomes
tmp_4_15686648_C_T 457 V>I No 1000Genomes
ENSVATH06812868 498 V>F No 1000Genomes
tmp_4_15686354_A_T 524 L>H No 1000Genomes
ENSVATH06812866 553 I>T No 1000Genomes
ENSVATH12351938 565 I>M No 1000Genomes
tmp_4_15686188_T_G 579 Q>H No 1000Genomes
ENSVATH00548437 583 Q>P Number of days following stratification to opening of first flower. the experiment was stopped at 200 d and accessions that had not flowered at that point were assigned a value of 200 [18c and 16 hrs daylight] Plants were checked bi-weekly for presence of first buds and the average flowering time of 4 plants of the same accession were collected [22c and 16 hrs daylight] [EnsemblGenome] No 1000Genomes
ENSVATH14327018 602 M>I No 1000Genomes
ENSVATH06812865 609 N>K No 1000Genomes
ENSVATH12351937 610 S>P No 1000Genomes
ENSVATH12351936 613 G>S No 1000Genomes
tmp_4_15686014_A_C 637 Y>* No 1000Genomes
tmp_4_15686015_T_G 637 Y>S No 1000Genomes
ENSVATH06812864 639 A>P No 1000Genomes
ENSVATH00548435 642 L>M No 1000Genomes
ENSVATH12351935 673 S>Y No 1000Genomes
tmp_4_15685903_T_C 674 S>W No 1000Genomes

No associated diseases with Q9SUU1

3 regional properties for Q9SUU1

Type Name Position InterPro Accession
domain Bicarbonate transporter-like, transmembrane domain 7 - 177 IPR011531-1
domain Bicarbonate transporter-like, transmembrane domain 197 - 376 IPR011531-2
domain Bicarbonate transporter-like, transmembrane domain 455 - 545 IPR011531-3

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
solute:inorganic anion antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion(out) + solute(in) = inorganic anion (in) + solute(out).
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

2 GO annotations of biological process

Name Definition
ion homeostasis Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

24 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9GL77 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 Bos taurus (Bovine) PR
Q32LP4 SLC4A10 Sodium-driven chloride bicarbonate exchanger Bos taurus (Bovine) PR
P02730 SLC4A1 Band 3 anion transport protein Homo sapiens (Human) PR
P04920 SLC4A2 Anion exchange protein 2 Homo sapiens (Human) PR
Q2Y0W8 SLC4A8 Electroneutral sodium bicarbonate exchanger 1 Homo sapiens (Human) PR
Q6U841 SLC4A10 Sodium-driven chloride bicarbonate exchanger Homo sapiens (Human) PR
Q9Y6M7 SLC4A7 Sodium bicarbonate cotransporter 3 Homo sapiens (Human) PR
Q9Y6R1 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 Homo sapiens (Human) PR
Q8NBS3 SLC4A11 Solute carrier family 4 member 11 Homo sapiens (Human) PR
O88343 Slc4a4 Electrogenic sodium bicarbonate cotransporter 1 Mus musculus (Mouse) PR
P04919 Slc4a1 Band 3 anion transport protein Mus musculus (Mouse) PR
P13808 Slc4a2 Anion exchange protein 2 Mus musculus (Mouse) PR
P16283 Slc4a3 Anion exchange protein 3 Mus musculus (Mouse) PR
Q5DTL9 Slc4a10 Sodium-driven chloride bicarbonate exchanger Mus musculus (Mouse) PR
Q8JZR6 Slc4a8 Electroneutral sodium bicarbonate exchanger 1 Mus musculus (Mouse) PR
A2AJN7 Slc4a11 Solute carrier family 4 member 11 Mus musculus (Mouse) PR
Q8BTY2 Slc4a7 Sodium bicarbonate cotransporter 3 Mus musculus (Mouse) PR
Q4U116 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 Sus scrofa (Pig) PR
Q80ZA5 Slc4a10 Sodium-driven chloride bicarbonate exchanger Rattus norvegicus (Rat) PR
Q9JI66 Slc4a4 Electrogenic sodium bicarbonate cotransporter 1 Rattus norvegicus (Rat) PR
Q9R1N3 Slc4a7 Sodium bicarbonate cotransporter 3 Rattus norvegicus (Rat) PR
Q3E954 BOR6 Probable boron transporter 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M1P7 BOR2 Probable boron transporter 2 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VYR7 BOR1 Boron transporter 1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEGVKFPFGG IINDFNGRRK CYKQDWLAAF NSGVRILAPT LYIFIASALP VIAFGEQLSR
70 80 90 100 110 120
ETDRSLGIAE SLASTALCGI IHSVFGGQPL LIVGVAEPTI IMYTYLHSFS KSRPELGQKL
130 140 150 160 170 180
YLAWAGWVCV WTAVLLMLLA MLNACNIISR FTRIAGELFG MLITVLFIQE AVKGLIGEFL
190 200 210 220 230 240
VPKSDDPSLE VYQFQWRYTN GLLAVIFSFG LLYTALKSRR ARSWKYGFRW MRGFIGDYGT
250 260 270 280 290 300
LLMLVLWSAF SYTVPRNLPE GVPRRLELPL PWASESLYHW TVVKDMAKVP PLYILAAFIP
310 320 330 340 350 360
AIMIAGLYFF DHCVSAQMAQ QKEFNLKNPT AYHYDIFILG IMTLICGLLG LPPSNGVIPQ
370 380 390 400 410 420
SPMHTKSLAV LKKQQMRKKM VQKAKECMRE KASNSEIYGR MQDVFIEMET SPKATSVVKE
430 440 450 460 470 480
LENLKEAVMK ADDGGGETKG KKFDPEVHIE DHLPVRVNEQ RVSNLLQSVL VGLLILAVPV
490 500 510 520 530 540
LRMIPTSVLW GYFTYMAVDS LPGNQFWERL QLLFITPGRR FKVLEGLHAS FVEIVPYKSI
550 560 570 580 590 600
VMFTLFQLLY FLICYGVTWI PVGGILFPLP FFILIALRQY ILQRLFDPSH LQVLDSSEYE
610 620 630 640 650 660
EMVGAPQRNS SFGFNGELRE AHNIPLSVVE NSEDEFYDAE ILDEITTSRG ELKHRTLSVK
670
EDRSQMVKIY NHS