Q3E954

PR
Gene name
BOR6 (At5g25430, F18G18.170)
Protein name
Probable boron transporter 6
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G25430
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

357-467 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3E954

Entry ID Method Resolution Chain Position Source
AF-Q3E954-F1 Predicted AlphaFoldDB

97 variants for Q3E954

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH03122823 2 K>E No 1000Genomes
tmp_5_8851258_G_A 3 S>N No 1000Genomes
tmp_5_8851268_A_T 6 E>D No 1000Genomes
ENSVATH03122824 6 E>K No 1000Genomes
ENSVATH03122825 7 S>N No 1000Genomes
ENSVATH00647670 7 S>R No 1000Genomes
ENSVATH11045374 21 R>Q No 1000Genomes
tmp_5_8851339_G_T 30 R>L No 1000Genomes
tmp_5_8851450_G_A 40 A>T No 1000Genomes
ENSVATH00647672 42 T>I No 1000Genomes
tmp_5_8851481_C_T 50 S>F No 1000Genomes
tmp_5_8851492_G_A 54 V>I No 1000Genomes
ENSVATH11045415 55 A>S No 1000Genomes
ENSVATH00647676 66 G>R No 1000Genomes
ENSVATH07042701 74 L>S No 1000Genomes
ENSVATH11045419 115 R>K No 1000Genomes
tmp_5_8851771_C_T 116 P>S No 1000Genomes
ENSVATH00647679 117 D>E No 1000Genomes
tmp_5_8851774_G_A 117 D>N No 1000Genomes
tmp_5_8851780_G_A 119 G>S No 1000Genomes
ENSVATH07042702 124 L>R No 1000Genomes
tmp_5_8851798_G_T 125 A>S No 1000Genomes
ENSVATH07042707 130 V>I No 1000Genomes
ENSVATH07042709 143 I>V No 1000Genomes
tmp_5_8851962_A_G 150 I>V No 1000Genomes
tmp_5_8851978_G_A 155 R>K No 1000Genomes
ENSVATH03122839 184 P>S No 1000Genomes
ENSVATH07042712 185 E>K No 1000Genomes
ENSVATH07042712 185 E>Q No 1000Genomes
tmp_5_8852151_G_A 190 E>K No 1000Genomes
ENSVATH07042713 192 G>R No 1000Genomes
ENSVATH03122841 195 H>N No 1000Genomes
ENSVATH03122841 195 H>Y No 1000Genomes
ENSVATH03122842 198 L>F No 1000Genomes
ENSVATH07042715 201 A>V No 1000Genomes
tmp_5_8852206_T_A 208 I>N No 1000Genomes
ENSVATH00647682 214 L>V No 1000Genomes
tmp_5_8852233_C_G 217 A>G No 1000Genomes
tmp_5_8852379_G_A 241 G>D No 1000Genomes
tmp_5_8852385_C_T 243 P>L No 1000Genomes
tmp_5_8852430_G_A 258 S>N No 1000Genomes
tmp_5_8852447_G_A 264 V>I No 1000Genomes
tmp_5_8852480_G_A 275 E>K No 1000Genomes
tmp_5_8852608_A_G 290 K>R No 1000Genomes
ENSVATH03122847 293 I>V No 1000Genomes
ENSVATH11045465 294 M>I No 1000Genomes
ENSVATH00647686 297 L>F No 1000Genomes
tmp_5_8852659_C_T 307 A>V No 1000Genomes
ENSVATH03122849 315 S>N No 1000Genomes
tmp_5_8852755_T_A 339 F>Y No 1000Genomes
ENSVATH00647691 353 L>F No 1000Genomes
tmp_5_8852928_T_C 365 M>T No 1000Genomes
tmp_5_8852955_A_G 374 N>S No 1000Genomes
tmp_5_8853072_A_T 388 E>V No 1000Genomes
ENSVATH07042721 411 E>K No 1000Genomes
ENSVATH03122863 413 S>C No 1000Genomes
ENSVATH07042722 418 N>S No 1000Genomes
tmp_5_8853284_T_G 431 V>G No 1000Genomes
ENSVATH11045519 435 D>N No 1000Genomes
tmp_5_8853316_G_A 442 G>R No 1000Genomes
tmp_5_8853325_G_A 445 D>N No 1000Genomes
tmp_5_8853332_A_G 447 D>G No 1000Genomes
tmp_5_8853334_G_A 448 V>I No 1000Genomes
tmp_5_8853337_C_T 449 H>Y No 1000Genomes
ENSVATH11045520 451 E>G No 1000Genomes
ENSVATH03122874 463 V>L No 1000Genomes
tmp_5_8853393_G_T 467 L>F No 1000Genomes
tmp_5_8853403_C_A 471 L>I No 1000Genomes
tmp_5_8853416_C_A 475 T>K No 1000Genomes
ENSVATH07042727 478 A>V No 1000Genomes
ENSVATH00647694 480 T>P No 1000Genomes
ENSVATH03122875 489 V>I No 1000Genomes
ENSVATH03122876 496 Y>N No 1000Genomes
tmp_5_8853500_C_T 503 P>L No 1000Genomes
tmp_5_8853502_G_A 504 G>R No 1000Genomes
ENSVATH14193020 505 N>T No 1000Genomes
ENSVATH07042729 511 L>M No 1000Genomes
tmp_5_8853681_C_A 537 P>T No 1000Genomes
ENSVATH07042732 543 T>K No 1000Genomes
tmp_5_8853705_A_T 545 T>S No 1000Genomes
tmp_5_8853729_C_T 553 L>F No 1000Genomes
tmp_5_8853748_C_T 559 T>I No 1000Genomes
ENSVATH07042734 569 P>S No 1000Genomes
tmp_5_8853822_C_T 584 P>S No 1000Genomes
tmp_5_8853825_A_T 585 K>* No 1000Genomes
tmp_5_8853862_C_T 597 A>V No 1000Genomes
ENSVATH11045522 598 S>P No 1000Genomes
tmp_5_8853873_G_A 601 E>K No 1000Genomes
ENSVATH07042737 624 L>F No 1000Genomes
ENSVATH00647698 627 G>A No 1000Genomes
ENSVATH07042739 635 E>* No 1000Genomes
tmp_5_8854065_A_T 635 E>V No 1000Genomes
tmp_5_8854077_A_G 639 E>G No 1000Genomes
ENSVATH11045524 643 S>N No 1000Genomes
tmp_5_8854090_C_A 643 S>R No 1000Genomes
ENSVATH11045545 644 R>S No 1000Genomes
ENSVATH07042743 660 E>K No 1000Genomes

No associated diseases with Q3E954

3 regional properties for Q3E954

Type Name Position InterPro Accession
domain Bicarbonate transporter-like, transmembrane domain 9 - 189 IPR011531-1
domain Bicarbonate transporter-like, transmembrane domain 202 - 376 IPR011531-2
domain Bicarbonate transporter-like, transmembrane domain 456 - 546 IPR011531-3

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
solute:inorganic anion antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion(out) + solute(in) = inorganic anion (in) + solute(out).
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

2 GO annotations of biological process

Name Definition
ion homeostasis Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

24 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9GL77 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 Bos taurus (Bovine) PR
Q32LP4 SLC4A10 Sodium-driven chloride bicarbonate exchanger Bos taurus (Bovine) PR
P02730 SLC4A1 Band 3 anion transport protein Homo sapiens (Human) PR
P04920 SLC4A2 Anion exchange protein 2 Homo sapiens (Human) PR
Q2Y0W8 SLC4A8 Electroneutral sodium bicarbonate exchanger 1 Homo sapiens (Human) PR
Q6U841 SLC4A10 Sodium-driven chloride bicarbonate exchanger Homo sapiens (Human) PR
Q9Y6M7 SLC4A7 Sodium bicarbonate cotransporter 3 Homo sapiens (Human) PR
Q9Y6R1 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 Homo sapiens (Human) PR
Q8NBS3 SLC4A11 Solute carrier family 4 member 11 Homo sapiens (Human) PR
O88343 Slc4a4 Electrogenic sodium bicarbonate cotransporter 1 Mus musculus (Mouse) PR
P04919 Slc4a1 Band 3 anion transport protein Mus musculus (Mouse) PR
P13808 Slc4a2 Anion exchange protein 2 Mus musculus (Mouse) PR
P16283 Slc4a3 Anion exchange protein 3 Mus musculus (Mouse) PR
Q5DTL9 Slc4a10 Sodium-driven chloride bicarbonate exchanger Mus musculus (Mouse) PR
Q8JZR6 Slc4a8 Electroneutral sodium bicarbonate exchanger 1 Mus musculus (Mouse) PR
A2AJN7 Slc4a11 Solute carrier family 4 member 11 Mus musculus (Mouse) PR
Q8BTY2 Slc4a7 Sodium bicarbonate cotransporter 3 Mus musculus (Mouse) PR
Q4U116 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 Sus scrofa (Pig) PR
Q80ZA5 Slc4a10 Sodium-driven chloride bicarbonate exchanger Rattus norvegicus (Rat) PR
Q9JI66 Slc4a4 Electrogenic sodium bicarbonate cotransporter 1 Rattus norvegicus (Rat) PR
Q9R1N3 Slc4a7 Sodium bicarbonate cotransporter 3 Rattus norvegicus (Rat) PR
Q9M1P7 BOR2 Probable boron transporter 2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SUU1 BOR7 Probable boron transporter 7 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VYR7 BOR1 Boron transporter 1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKSEGESGPF QGILRDIEGR RKCYKQDWIR GIKTGIRILA PTCYIFFASS LPVVAFGEQL
70 80 90 100 110 120
SKHTGGALSA VETLASTSIC GIIHAIFGGQ PLLIVGVAEP TIIMYTYLYS FCISRPDIGR
130 140 150 160 170 180
ELYLAWVAWV CVWTSVLLIL LSIFNAGTII TRFTRIAGEL FGMLIAVLFL QEAIKGLISE
190 200 210 220 230 240
FHAPEIKNQE TGKSHFLLIY ANGLLAVIFS LGLLITALKS RRAKSWKYGF GWLRSFIGDY
250 260 270 280 290 300
GVPLMVLLWT ALSYTVPSEV LPSVPRRLFC PLPWEPASLY HWTVVKDMGK VPIMYILAAF
310 320 330 340 350 360
IPGVMIAGLY FFDHSVASQM AQQKEFNLKN PSAYHYDIFL LGIITLICGL LGLPPSNGVL
370 380 390 400 410 420
PQAPMHTKSL AVLNRQLIRK KMVKKAKECM KMKASKSEIY GRMQSVFIEM ETSPPQDNSV
430 440 450 460 470 480
ATDLKELKEV VMRPDEGGDT KGKFDPDVHI EANLPVRVNE QRVSNLLQSV LVGLTLLAVT
490 500 510 520 530 540
VIKMIPSSVL WGYFAYMAID SLPGNQFWER LLLLFIPPSR LFKVLEGVHA SFVELVPYRV
550 560 570 580 590 600
IVTFTLFQLV YFLLCYGMTW IPMAGIFFPA LFFLLISIRE HLLPKLFDMQ HLQVLDASDY
610 620 630 640 650 660
EEIVAAPIQH SSFAYRKLGS SHHLSEGEDE FYDAEILDEM TTSRGEIRIR TISFKEVHPE
670
PEEKHVTFEP H