Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9M1P7

Entry ID Method Resolution Chain Position Source
AF-Q9M1P7-F1 Predicted AlphaFoldDB

24 variants for Q9M1P7

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_23045591_G_T 15 L>I No 1000Genomes
tmp_3_23045108_C_T 117 G>R No 1000Genomes
tmp_3_23044905_T_A 157 E>D No 1000Genomes
ENSVATH06359721 190 V>M No 1000Genomes
tmp_3_23044172_C_A 289 V>F No 1000Genomes
tmp_3_23044162_A_C 292 V>G No 1000Genomes
ENSVATH02536514 424 R>K No 1000Genomes
ENSVATH06359716 433 F>S No 1000Genomes
ENSVATH06359715 452 I>V No 1000Genomes
ENSVATH02536513 478 V>I No 1000Genomes
ENSVATH12881525 516 L>F No 1000Genomes
tmp_3_23042917_T_C 603 E>G No 1000Genomes
tmp_3_23042908_G_A 606 P>L No 1000Genomes
tmp_3_23042783_C_T 619 M>I No 1000Genomes
tmp_3_23042782_C_T 620 G>R No 1000Genomes
tmp_3_23042747_A_C 631 I>M No 1000Genomes
tmp_3_23042724_C_T 639 S>N No 1000Genomes
tmp_3_23042674_A_C 656 S>A No 1000Genomes
ENSVATH06359710 668 F>L No 1000Genomes
ENSVATH06359709 671 R>G No 1000Genomes
ENSVATH06359708 675 L>V No 1000Genomes
tmp_3_23042589_G_A 684 S>F No 1000Genomes
ENSVATH06359707 687 G>R No 1000Genomes
ENSVATH00432072 702 S>P No 1000Genomes

No associated diseases with Q9M1P7

2 regional properties for Q9M1P7

Type Name Position InterPro Accession
domain Peptidase M24 127 - 433 IPR000994
binding_site Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site 211 - 227 IPR018349

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
active borate transmembrane transporter activity Enables the transport of borate across a membrane against the concentration gradient.
solute:inorganic anion antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion(out) + solute(in) = inorganic anion (in) + solute(out).
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

3 GO annotations of biological process

Name Definition
ion homeostasis Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
root development The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

24 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9GL77 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 Bos taurus (Bovine) PR
Q32LP4 SLC4A10 Sodium-driven chloride bicarbonate exchanger Bos taurus (Bovine) PR
P02730 SLC4A1 Band 3 anion transport protein Homo sapiens (Human) PR
P04920 SLC4A2 Anion exchange protein 2 Homo sapiens (Human) PR
Q2Y0W8 SLC4A8 Electroneutral sodium bicarbonate exchanger 1 Homo sapiens (Human) PR
Q6U841 SLC4A10 Sodium-driven chloride bicarbonate exchanger Homo sapiens (Human) PR
Q9Y6M7 SLC4A7 Sodium bicarbonate cotransporter 3 Homo sapiens (Human) PR
Q9Y6R1 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 Homo sapiens (Human) PR
Q8NBS3 SLC4A11 Solute carrier family 4 member 11 Homo sapiens (Human) PR
O88343 Slc4a4 Electrogenic sodium bicarbonate cotransporter 1 Mus musculus (Mouse) PR
P04919 Slc4a1 Band 3 anion transport protein Mus musculus (Mouse) PR
P13808 Slc4a2 Anion exchange protein 2 Mus musculus (Mouse) PR
P16283 Slc4a3 Anion exchange protein 3 Mus musculus (Mouse) PR
Q5DTL9 Slc4a10 Sodium-driven chloride bicarbonate exchanger Mus musculus (Mouse) PR
Q8JZR6 Slc4a8 Electroneutral sodium bicarbonate exchanger 1 Mus musculus (Mouse) PR
A2AJN7 Slc4a11 Solute carrier family 4 member 11 Mus musculus (Mouse) PR
Q8BTY2 Slc4a7 Sodium bicarbonate cotransporter 3 Mus musculus (Mouse) PR
Q4U116 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 Sus scrofa (Pig) PR
Q80ZA5 Slc4a10 Sodium-driven chloride bicarbonate exchanger Rattus norvegicus (Rat) PR
Q9JI66 Slc4a4 Electrogenic sodium bicarbonate cotransporter 1 Rattus norvegicus (Rat) PR
Q9R1N3 Slc4a7 Sodium bicarbonate cotransporter 3 Rattus norvegicus (Rat) PR
Q3E954 BOR6 Probable boron transporter 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SUU1 BOR7 Probable boron transporter 7 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VYR7 BOR1 Boron transporter 1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEETFVPFEG IKNDLKGRLM CYKQDWTGGI KAGFRILAPT TYIFFASAIP VISFGEQLER
70 80 90 100 110 120
STDGVLTAVQ TLASTAICGI IHSIIGGQPL LILGVAEPTV IMYTFMFNFA KGRPELGRNL
130 140 150 160 170 180
FLAWSGWVCV WTSLILFVLA ICGACSFINR FTRVAGELFG LLIAMLFMQQ AIKGLVDEFR
190 200 210 220 230 240
APAREDLKLV EFLPSWRFAN GMFALVLSFG LLITALRSRK ARSWRYGTGW LRSLVADYGV
250 260 270 280 290 300
PLMVLVWTGV SYIPTGDVPK GIPRRLFSPN PWSPGAYENW TVVKEMLQVP IVYIIGAFIP
310 320 330 340 350 360
ATMIAVLYYF DHSVASQLAQ QKEFNLRKPS SYHYDLLLLG FLTLMCGLLG IPPSNGVIPQ
370 380 390 400 410 420
SPMHTKSLAT LKYQLLRNRL VATARKSIKQ NASLGQLYGN MQDVYNQMQT PLVYQQPQGL
430 440 450 460 470 480
KELRESTIQA TTFTGNLDAP VDETLFDIEK EIDDLLPIEV KEQRVSNLLQ AVMVGGCVAA
490 500 510 520 530 540
MPLLKMIPTS VLWGYFAFMA IESLPGNQFW ERILLLFTAP SRRFKVLEDN HATFVETVPF
550 560 570 580 590 600
KTIAMFTIFQ TTYLLTCFGL TWIPIAGVMF PLLIMFLIPV RQYILPRFFK SAHLQDLDAA
610 620 630 640 650 660
EYEEAPALPF HLAVPEAEMG STASYPCDSE ILDEFITRSR GEFRHTCSPK VTSSTSTPVY
670 680 690 700
NRNLSQVFSP RVIDLRGEMS PRLSGKGQNS PKPSPLNPSS SSK