Q8VYR7
PR
Gene name |
BOR1 |
Protein name |
Boron transporter 1 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G47160 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q8VYR7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 5L25 | X-ray | 411 A | A | 1-645 | PDB |
| AF-Q8VYR7-F1 | Predicted | AlphaFoldDB |
13 variants for Q8VYR7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_19360706_C_T | 28 | G>S | No | 1000Genomes | |
| ENSVATH07920057 | 69 | V>G | No | 1000Genomes | |
| tmp_2_19359267_T_A | 334 | Y>F | No | 1000Genomes | |
| ENSVATH01997531 | 399 | D>E | No | 1000Genomes | |
| tmp_2_19358718_T_C | 438 | N>S | No | 1000Genomes | |
| ENSVATH13665514 | 475 | G>V | No | 1000Genomes | |
| ENSVATH00801441 | 548 | L>I | No | 1000Genomes | |
| tmp_2_19358009_T_C | 616 | T>A | No | 1000Genomes | |
| tmp_2_19357981_G_T | 625 | P>Q | No | 1000Genomes | |
| tmp_2_19357952_T_G | 635 | M>L | No | 1000Genomes | |
| tmp_2_19357892_A_G | 655 | S>P | No | 1000Genomes | |
| tmp_2_19357769_T_C | 696 | S>G | No | 1000Genomes | |
| ENSVATH13665512 | 697 | P>S | No | 1000Genomes |
No associated diseases with Q8VYR7
3 regional properties for Q8VYR7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Bicarbonate transporter-like, transmembrane domain | 7 - 180 | IPR011531-1 |
| domain | Bicarbonate transporter-like, transmembrane domain | 201 - 371 | IPR011531-2 |
| domain | Bicarbonate transporter-like, transmembrane domain | 458 - 548 | IPR011531-3 |
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| endosome membrane | The lipid bilayer surrounding an endosome. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| vacuolar membrane | The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| active borate transmembrane transporter activity | Enables the transport of borate across a membrane against the concentration gradient. |
| solute:inorganic anion antiporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion(out) + solute(in) = inorganic anion (in) + solute(out). |
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| borate transmembrane transport | The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals. |
| cellular response to boron-containing substance levels | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances. |
| ion homeostasis | Any process involved in the maintenance of an internal steady state of ions within an organism or cell. |
| response to boron-containing substance | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus. |
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
24 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9GL77 | SLC4A4 | Electrogenic sodium bicarbonate cotransporter 1 | Bos taurus (Bovine) | PR |
| Q32LP4 | SLC4A10 | Sodium-driven chloride bicarbonate exchanger | Bos taurus (Bovine) | PR |
| P02730 | SLC4A1 | Band 3 anion transport protein | Homo sapiens (Human) | PR |
| P04920 | SLC4A2 | Anion exchange protein 2 | Homo sapiens (Human) | PR |
| Q2Y0W8 | SLC4A8 | Electroneutral sodium bicarbonate exchanger 1 | Homo sapiens (Human) | PR |
| Q6U841 | SLC4A10 | Sodium-driven chloride bicarbonate exchanger | Homo sapiens (Human) | PR |
| Q9Y6M7 | SLC4A7 | Sodium bicarbonate cotransporter 3 | Homo sapiens (Human) | PR |
| Q9Y6R1 | SLC4A4 | Electrogenic sodium bicarbonate cotransporter 1 | Homo sapiens (Human) | PR |
| Q8NBS3 | SLC4A11 | Solute carrier family 4 member 11 | Homo sapiens (Human) | PR |
| O88343 | Slc4a4 | Electrogenic sodium bicarbonate cotransporter 1 | Mus musculus (Mouse) | PR |
| P04919 | Slc4a1 | Band 3 anion transport protein | Mus musculus (Mouse) | PR |
| P13808 | Slc4a2 | Anion exchange protein 2 | Mus musculus (Mouse) | PR |
| P16283 | Slc4a3 | Anion exchange protein 3 | Mus musculus (Mouse) | PR |
| Q5DTL9 | Slc4a10 | Sodium-driven chloride bicarbonate exchanger | Mus musculus (Mouse) | PR |
| Q8JZR6 | Slc4a8 | Electroneutral sodium bicarbonate exchanger 1 | Mus musculus (Mouse) | PR |
| A2AJN7 | Slc4a11 | Solute carrier family 4 member 11 | Mus musculus (Mouse) | PR |
| Q8BTY2 | Slc4a7 | Sodium bicarbonate cotransporter 3 | Mus musculus (Mouse) | PR |
| Q4U116 | SLC4A4 | Electrogenic sodium bicarbonate cotransporter 1 | Sus scrofa (Pig) | PR |
| Q80ZA5 | Slc4a10 | Sodium-driven chloride bicarbonate exchanger | Rattus norvegicus (Rat) | PR |
| Q9JI66 | Slc4a4 | Electrogenic sodium bicarbonate cotransporter 1 | Rattus norvegicus (Rat) | PR |
| Q9R1N3 | Slc4a7 | Sodium bicarbonate cotransporter 3 | Rattus norvegicus (Rat) | PR |
| Q3E954 | BOR6 | Probable boron transporter 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M1P7 | BOR2 | Probable boron transporter 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SUU1 | BOR7 | Probable boron transporter 7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEETFVPFEG | IKNDLKGRLM | CYKQDWTGGF | KAGFRILAPT | TYIFFASAIP | VISFGEQLER |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STDGVLTAVQ | TLASTAICGM | IHSIIGGQPL | LILGVAEPTV | IMYTFMFNFA | KARPELGRDL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FLAWSGWVCV | WTALMLFVLA | ICGACSIINR | FTRVAGELFG | LLIAMLFMQQ | AIKGLVDEFR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IPERENQKLK | EFLPSWRFAN | GMFALVLSFG | LLLTGLRSRK | ARSWRYGTGW | LRSLIADYGV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PLMVLVWTGV | SYIPAGDVPK | GIPRRLFSPN | PWSPGAYGNW | TVVKEMLDVP | IVYIIGAFIP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ASMIAVLYYF | DHSVASQLAQ | QKEFNLRKPS | SYHYDLLLLG | FLTLMCGLLG | VPPSNGVIPQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SPMHTKSLAT | LKYQLLRNRL | VATARRSIKT | NASLGQLYDN | MQEAYHHMQT | PLVYQQPQGL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KELKESTIQA | TTFTGNLNAP | VDETLFDIEK | EIDDLLPVEV | KEQRVSNLLQ | STMVGGCVAA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MPILKMIPTS | VLWGYFAFMA | IESLPGNQFW | ERILLLFTAP | SRRFKVLEDY | HATFVETVPF |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KTIAMFTLFQ | TTYLLICFGL | TWIPIAGVMF | PLMIMFLIPV | RQYLLPRFFK | GAHLQDLDAA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| EYEEAPALPF | NLAAETEIGS | TTSYPGDLEI | LDEVMTRSRG | EFRHTSSPKV | TSSSSTPVNN |
| 670 | 680 | 690 | 700 | ||
| RSLSQVFSPR | VSGIRLGQMS | PRVVGNSPKP | ASCGRSPLNQ | SSSN |