Q9SZR9
PR
Gene name |
ABCG9 |
Protein name |
ABC transporter G family member 9 |
Names |
ABC transporter ABCG.9, AtABCG9, Probable white-brown complex homolog protein 9, AtWBC9 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G27420 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SZR9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SZR9-F1 | Predicted | AlphaFoldDB |
43 variants for Q9SZR9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_13714760_G_A | 13 | P>L | No | 1000Genomes | |
| ENSVATH00541096 | 15 | A>E | No | 1000Genomes | |
| tmp_4_13714730_A_C | 23 | L>R | No | 1000Genomes | |
| ENSVATH06785026 | 35 | V>I | No | 1000Genomes | |
| tmp_4_13714421_A_T | 39 | F>Y | No | 1000Genomes | |
| tmp_4_13714403_G_T | 45 | T>K | No | 1000Genomes | |
| tmp_4_13714397_T_G | 47 | K>T | No | 1000Genomes | |
| ENSVATH06785024 | 61 | T>I | No | 1000Genomes | |
| tmp_4_13714232_C_G | 102 | G>A | No | 1000Genomes | |
| tmp_4_13714184_G_A | 118 | P>L | No | 1000Genomes | |
| ENSVATH12259795 | 147 | V>I | No | 1000Genomes | |
| tmp_4_13714058_T_C | 160 | K>R | No | 1000Genomes | |
| ENSVATH12259764 | 161 | Q>R | No | 1000Genomes | |
| tmp_4_13714029_C_T | 170 | V>I | No | 1000Genomes | |
| tmp_4_13714013_C_T | 175 | G>D | No | 1000Genomes | |
| tmp_4_13713759_C_T | 260 | D>N | No | 1000Genomes | |
| ENSVATH14302307 | 280 | M>I | No | 1000Genomes | |
| ENSVATH06785021 | 284 | A>S | No | 1000Genomes | |
| ENSVATH12259763 | 286 | V>I | No | 1000Genomes | |
| tmp_4_13713663_C_T | 292 | V>I | No | 1000Genomes | |
| tmp_4_13713619_G_T | 306 | N>K | No | 1000Genomes | |
| tmp_4_13713508_C_T | 309 | G>E | No | 1000Genomes | |
| tmp_4_13713463_A_G | 324 | V>A | No | 1000Genomes | |
| tmp_4_13713406_T_C | 343 | D>G | No | 1000Genomes | |
| tmp_4_13713381_C_G | 351 | E>D | No | 1000Genomes | |
| tmp_4_13713347_A_G | 363 | W>R | No | 1000Genomes | |
| tmp_4_13713317_C_A | 373 | V>F | No | 1000Genomes | |
| ENSVATH06785017 | 393 | A>S | No | 1000Genomes | |
| ENSVATH12259762 | 412 | S>F | No | 1000Genomes | |
| tmp_4_13713020_C_G | 444 | R>P | No | 1000Genomes | |
| ENSVATH06785015 | 445 | A>T | No | 1000Genomes | |
| tmp_4_13712999_C_A | 451 | R>L | No | 1000Genomes | |
| tmp_4_13712973_G_A | 460 | P>S | No | 1000Genomes | |
| ENSVATH00541091 | 463 | L>M | No | 1000Genomes | |
| tmp_4_13712886_C_T | 489 | G>S | No | 1000Genomes | |
| ENSVATH06785011 | 498 | F>I | No | 1000Genomes | |
| tmp_4_13712798_A_T | 518 | L>Q | No | 1000Genomes | |
| tmp_4_13712796_C_G | 519 | G>R | No | 1000Genomes | |
| ENSVATH00541090 | 577 | A>T | No | 1000Genomes | |
| tmp_4_13712594_T_C | 586 | N>S | No | 1000Genomes | |
| tmp_4_13712587_T_G | 588 | K>N | No | 1000Genomes | |
| tmp_4_13712526_C_G | 609 | V>L | No | 1000Genomes | |
| tmp_4_13712484_C_G | 623 | V>L | No | 1000Genomes |
No associated diseases with Q9SZR9
5 regional properties for Q9SZR9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 37 - 292 | IPR003439 |
| domain | AAA+ ATPase domain | 76 - 269 | IPR003593 |
| domain | ABC-2 type transporter, transmembrane domain | 369 - 573 | IPR013525 |
| conserved_site | ABC transporter-like, conserved site | 192 - 206 | IPR017871 |
| domain | ABC transporter family G domain | 249 - 321 | IPR043926 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| pollen coat | A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATPase-coupled transmembrane transporter activity | Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. |
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cotyledon vascular tissue pattern formation | Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants. |
| glycoside transport | The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| pollen wall assembly | The formation of reticulate pollen wall pattern consisting of two layers, exine and intine. |
| stem vascular tissue pattern formation | Vascular tissue pattern formation as it occurs in the stem of vascular plants. |
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
15 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P45844 | ABCG1 | ATP-binding cassette sub-family G member 1 | Homo sapiens (Human) | PR |
| Q9H172 | ABCG4 | ATP-binding cassette sub-family G member 4 | Homo sapiens (Human) | PR |
| Q64343 | Abcg1 | ATP-binding cassette sub-family G member 1 | Mus musculus (Mouse) | PR |
| Q99PE8 | Abcg5 | ATP-binding cassette sub-family G member 5 | Mus musculus (Mouse) | PR |
| Q99PE7 | Abcg5 | ATP-binding cassette sub-family G member 5 | Rattus norvegicus (Rat) | PR |
| Q09466 | wht-3 | ABC transporter ATP-binding protein/permease wht-3 | Caenorhabditis elegans | PR |
| Q11180 | wht-1 | ABC transporter ATP-binding protein/permease wht-1 | Caenorhabditis elegans | PR |
| Q9M2V6 | ABCG17 | ABC transporter G family member 17 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAG3 | ABCG24 | ABC transporter G family member 24 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAH4 | ABCG10 | ABC transporter G family member 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81016 | ABCG32 | ABC transporter G family member 32 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZUT8 | ABCG33 | ABC transporter G family member 33 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LFH0 | ABCG37 | ABC transporter G family member 37 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC81 | ABCG43 | ABC transporter G family member 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GZ52 | ABCG30 | ABC transporter G family member 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDNQEVSMDV | ETPIAKTNDD | RSLPFSIFKK | ANNPVTLKFE | NLVYTVKLKD | SQGCFGKNDK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TEERTILKGL | TGIVKPGEIL | AMLGPSGSGK | TSLLTALGGR | VGEGKGKLTG | NISYNNKPLS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KAVKRTTGFV | TQDDALYPNL | TVTETLVFTA | LLRLPNSFKK | QEKIKQAKAV | MTELGLDRCK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DTIIGGPFLR | GVSGGERKRV | SIGQEILINP | SLLFLDEPTS | GLDSTTAQRI | VSILWELARG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GRTVVTTIHQ | PSSRLFYMFD | KLLLLSEGNP | VYFGLGSNAM | DYFASVGYSP | LVERINPSDF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLDIANGVGS | DESQRPEAMK | AALVAFYKTN | LLDSVINEVK | GQDDLCNKPR | ESSRVATNTY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GDWPTTWWQQ | FCVLLKRGLK | QRRHDSFSGM | KVAQIFIVSF | LCGLLWWQTK | ISRLQDQIGL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LFFISSFWAF | FPLFQQIFTF | PQERAMLQKE | RSSGMYRLSP | YFLSRVVGDL | PMELILPTCF |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LVITYWMAGL | NHNLANFFVT | LLVLLVHVLV | SGGLGLALGA | LVMDQKSATT | LGSVIMLTFL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LAGGYYVQHV | PVFISWIKYV | SIGYYTYKLL | ILGQYTANEL | YPCGDNGKLR | CHVGDFEGIK |
| 610 | 620 | 630 | |||
| HIGFNSGLVS | ALALTAMLVV | YRVIAYIALT | RIGKTKSG |