AiPD: Autoinhibited Protein Database

Gene name	ABCG10 (WBC10, At1g53270, F12M16.17)
Protein name	ABC transporter G family member 10
Names	ABC transporter ABCG.10, AtABCG10, Probable white-brown complex homolog protein 10, AtWBC10
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT1G53270
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

280-357 (Predicted disordered autoinhibitory region) PR

280-357 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9MAH4-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_1_19862899_C_T	8	P>S	No	1000Genomes
ENSVATH04952073	12	G>R	No	1000Genomes
ENSVATH00095772	14	E>K	No	1000Genomes
ENSVATH01363501	27	R>S	No	1000Genomes
tmp_1_19862965_G_C	30	G>R	No	1000Genomes
ENSVATH13551968	50	I>F	No	1000Genomes
ENSVATH04952075	62	E>A	No	1000Genomes
ENSVATH13551971	93	Q>P	No	1000Genomes
tmp_1_19863160_C_T	95	L>F	No	1000Genomes
ENSVATH14305891	98	G>R	No	1000Genomes
tmp_1_19863180_G_T	101	M>I	No	1000Genomes
tmp_1_19863287_T_G	137	L>R	No	1000Genomes
ENSVATH04952077	140	K>R	No	1000Genomes
ENSVATH01363503	142	K>E	No	1000Genomes
tmp_1_19863308_C_T	144	A>V	No	1000Genomes
ENSVATH13551973	150	R>M	No	1000Genomes
ENSVATH04952078	158	E>Q	No	1000Genomes
ENSVATH00095777	159	H>N	No	1000Genomes
ENSVATH01363506	213	T>M	No	1000Genomes
ENSVATH13551974	223	G>S	No	1000Genomes
tmp_1_19863595_C_G	240	Q>E	No	1000Genomes
ENSVATH00095780	251	M>L	No	1000Genomes
ENSVATH13551975	263	Q>H	No	1000Genomes
tmp_1_19863739_A_T	288	S>C	No	1000Genomes
ENSVATH04952080	291	P>S	No	1000Genomes
ENSVATH04952080	291	P>T	No	1000Genomes
tmp_1_19863766_T_A	297	C>S	No	1000Genomes
ENSVATH04952081	315	S>I	No	1000Genomes
tmp_1_19863865_G_A	330	V>M	No	1000Genomes
ENSVATH00095783	339	Q>K	No	1000Genomes
ENSVATH13551978	356	A>G	No	1000Genomes
ENSVATH13551980	384	R>Q	No	1000Genomes
tmp_1_19864049_T_C	391	I>T	No	1000Genomes
tmp_1_19864366_G_A	497	V>I	No	1000Genomes
ENSVATH04952090	544	R>Q	No	1000Genomes
tmp_1_19864510_G_A	545	G>R	No	1000Genomes
ENSVATH00095787	548	F>S	No	1000Genomes
tmp_1_19864588_G_A	571	V>I	No	1000Genomes
tmp_1_19864645_A_G	590	S>G	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	ABC transporter-like, ATP-binding domain	19 - 274	IPR003439
domain	AAA+ ATPase domain	60 - 249	IPR003593
domain	ABC-2 type transporter, transmembrane domain	333 - 543	IPR013525
conserved_site	ABC transporter-like, conserved site	173 - 187	IPR017871

		Description
EC Number
Subcellular Localization	Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

Name	Definition
ABC-type transporter activity	Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
ATP binding	Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATPase-coupled transmembrane transporter activity	Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.

Name	Definition
transmembrane transport	The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P45844	ABCG1	ATP-binding cassette sub-family G member 1	Homo sapiens (Human)	PR
Q9H172	ABCG4	ATP-binding cassette sub-family G member 4	Homo sapiens (Human)	PR
Q64343	Abcg1	ATP-binding cassette sub-family G member 1	Mus musculus (Mouse)	PR
Q99PE8	Abcg5	ATP-binding cassette sub-family G member 5	Mus musculus (Mouse)	PR
Q99PE7	Abcg5	ATP-binding cassette sub-family G member 5	Rattus norvegicus (Rat)	PR
Q09466	wht-3	ABC transporter ATP-binding protein/permease wht-3	Caenorhabditis elegans	PR
Q11180	wht-1	ABC transporter ATP-binding protein/permease wht-1	Caenorhabditis elegans	PR
Q9M2V6	ABCG17	ABC transporter G family member 17	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9MAG3	ABCG24	ABC transporter G family member 24	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SZR9	ABCG9	ABC transporter G family member 9	Arabidopsis thaliana (Mouse-ear cress)	PR
O81016	ABCG32	ABC transporter G family member 32	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9ZUT8	ABCG33	ABC transporter G family member 33	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9LFH0	ABCG37	ABC transporter G family member 37	Arabidopsis thaliana (Mouse-ear cress)	PR
Q7PC81	ABCG43	ABC transporter G family member 43	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8GZ52	ABCG30	ABC transporter G family member 30	Arabidopsis thaliana (Mouse-ear cress)	PR