AiPD: Autoinhibited Protein Database

Q9H172

Gene name	ABCG4
Protein name	ATP-binding cassette sub-family G member 4
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:64137
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-86 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-86 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q9H172

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9H172-F1	Predicted				AlphaFoldDB

443 variants for Q9H172

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA174732 rs193920956 CA6315897 RCV000149295	79	R>S	Malignant tumor of prostate [ClinVar]	Yes	ClinGen ClinVar ExAC dbSNP gnomAD
CA382972480 rs780697967	2	A>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6315855 rs780697967	2	A>V		No	ClinGen ExAC TOPMed gnomAD
rs556090631 CA6315857	5	A>G		No	ClinGen 1000Genomes ExAC gnomAD
CA6315856 rs556090631	5	A>V		No	ClinGen 1000Genomes ExAC gnomAD
rs748349948 CA6315859	6	L>V		No	ClinGen ExAC gnomAD
CA382972620 rs1211588013	9	V>E		No	ClinGen gnomAD
rs1312211427 CA382972612	9	V>L		No	ClinGen TOPMed gnomAD
CA382972616 rs1312211427	9	V>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs749303159 CA6315862	10	G>D		No	ClinGen ExAC gnomAD
CA382972668 rs1592300984	11	C>W		No	ClinGen Ensembl
rs1285852678 CA382972691	13	L>V		No	ClinGen TOPMed
rs760610599 CA6315865	14	G>A		No	ClinGen ExAC TOPMed gnomAD
rs113286118 CA6315867	15	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6315866 rs763828257	15	P>S		No	ClinGen ExAC TOPMed gnomAD
rs1425994328 CA382972758	16	G>E		No	ClinGen gnomAD
CA6315868 rs761710828	17	A>P		No	ClinGen ExAC TOPMed gnomAD
CA6315869 rs761710828	17	A>S		No	ClinGen ExAC TOPMed gnomAD
CA229643404 rs535425291	18	V>A		No	ClinGen 1000Genomes
CA6315871 rs757980952	19	A>D		No	ClinGen ExAC gnomAD
CA229643406 rs1056691142	19	A>T		No	ClinGen gnomAD
CA229643418 rs757980952	19	A>V		No	ClinGen ExAC gnomAD
CA382972833 rs765996611	20	M>L		No	ClinGen ExAC gnomAD
rs765996611 CA6315872	20	M>V		No	ClinGen ExAC gnomAD
rs896751158 CA229643453	22	V>L		No	ClinGen gnomAD
rs896751158 CA382972871	22	V>M		No	ClinGen gnomAD
rs752059482 CA6315873	23	T>K		No	ClinGen ExAC TOPMed gnomAD
CA382972899 rs752059482	23	T>M		No	ClinGen ExAC TOPMed gnomAD
rs1370319134 CA382972929	27	G>W		No	ClinGen gnomAD
rs1026169077 CA229643520	28	A>G		No	ClinGen TOPMed
TCGA novel	28	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA382973011 rs1316938454	30	P>H		No	ClinGen gnomAD
rs1045464167 CA229643526	30	P>S		No	ClinGen TOPMed gnomAD
rs1232511268 CA382973035	32	V>M		No	ClinGen TOPMed
rs1198810776 CA382973077	34	T>I		No	ClinGen gnomAD
rs572504625 CA6315877	35	T>A		No	ClinGen 1000Genomes ExAC gnomAD
rs777842874 CA6315878	36	H>Q		No	ClinGen ExAC TOPMed gnomAD
rs1592301156 CA382973199	40	V>G		No	ClinGen Ensembl
rs1565812180 CA382973279	44	I>V		No	ClinGen Ensembl
rs147880811 CA6315879	45	T>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA6315880 rs770930131	47	A>T		No	ClinGen ExAC gnomAD
CA6315882 rs746909495	49	R>H		No	ClinGen ExAC TOPMed gnomAD
CA6315883 rs768550146	50	F>L		No	ClinGen ExAC gnomAD
rs761500962 CA6315885	55	K>R		No	ClinGen ExAC gnomAD
TCGA novel	56	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA382973585 rs1160569038	56	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA6315887 rs769699547	60	D>G		No	ClinGen ExAC gnomAD
rs1398632499 CA382973673	60	D>Y		No	ClinGen gnomAD
CA382973735 rs1218889667	62	E>Q		No	ClinGen TOPMed gnomAD
CA382973784 rs1461324097	63	F>L		No	ClinGen TOPMed
CA382973796 rs1271622785	64	V>L		No	ClinGen TOPMed gnomAD
rs1271622785 CA382973793	64	V>M		No	ClinGen TOPMed gnomAD
CA382973825 rs1161903548	65	E>D		No	ClinGen TOPMed
rs1353787206 CA382973828	66	L>M		No	ClinGen gnomAD
TCGA novel	68	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765941668 CA6315890	71	R>P		No	ClinGen ExAC gnomAD
TCGA novel	71	R>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs759152966 CA382973981	73	G>A		No	ClinGen ExAC TOPMed gnomAD
CA6315892 rs759152966	73	G>E		No	ClinGen ExAC TOPMed gnomAD
rs751142020 CA6315891	73	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1489525923 CA382973998	74	P>L		No	ClinGen TOPMed
rs199826436 CA6315893	74	P>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA382974044 rs1211759170	76	W>*		No	ClinGen TOPMed
rs1367006399 CA382974071	77	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA6315895 rs756429171	79	R>K		No	ClinGen ExAC gnomAD
rs756429171 CA6315896	79	R>T		No	ClinGen ExAC gnomAD
CA382888892 rs1318958883	81	Y>F		No	ClinGen TOPMed
rs757667984 CA6315916	83	T>I		No	ClinGen ExAC gnomAD
TCGA novel	85	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	86	K>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA382889048 rs1565813615	87	C>Y		No	ClinGen Ensembl
TCGA novel	89	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA382889154 rs1241015264	91	K>E		No	ClinGen gnomAD
CA6315918 rs750712652	91	K>N		No	ClinGen ExAC TOPMed gnomAD
CA6315920 rs758347342	94	R>C		No	ClinGen ExAC TOPMed gnomAD
CA382889231 rs758347342	94	R>G		No	ClinGen ExAC TOPMed gnomAD
rs145297995 CA6315921	94	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA6315922 rs145297995	94	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs764723664 CA6315923	95	R>Q		No	ClinGen ExAC
rs370550232 CA6315925	95	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA6315924 rs756111918	95	R>W		No	ClinGen ExAC TOPMed gnomAD
rs754280930 CA6315926	97	L>K		No	ClinGen ExAC
rs1592303982 CA382889341	98	I>T		No	ClinGen Ensembl
rs749064882 CA6315927	100	I>V		No	ClinGen ExAC gnomAD
rs1334565539 CA382889445	101	M>T		No	ClinGen TOPMed
TCGA novel	103	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs373954461 CA6315928	104	S>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA6315929 rs774139491	106	A>D		No	ClinGen ExAC gnomAD
rs1565813685 CA382889705	110	T>A		No	ClinGen Ensembl
rs1400833794 CA382889714	110	T>I		No	ClinGen TOPMed
CA229597064 rs909250242	112	M>V		No	ClinGen TOPMed
CA382889850 rs1465141157	114	I>M		No	ClinGen gnomAD
CA382889951 rs1592304041	117	G>A		No	ClinGen Ensembl
rs1407919666 CA382889940	117	G>R		No	ClinGen gnomAD
rs1291570989 CA382890133	120	E>K		No	ClinGen gnomAD
CA382890152 rs1377509758	120	E>V		No	ClinGen TOPMed
CA6315945 rs749302228	124	K>Q		No	ClinGen ExAC gnomAD
TCGA novel	125	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1333174402 CA382890270	125	G>W		No	ClinGen TOPMed
rs1471929293 CA382890302	126	Q>*		No	ClinGen gnomAD
CA382890301 rs1471929293	126	Q>K		No	ClinGen gnomAD
CA6315947 rs778862594	132	R>S		No	ClinGen ExAC gnomAD
rs771787304 CA6315949	134	R>Q		No	ClinGen ExAC gnomAD
rs745462090 CA6315948	134	R>W		No	ClinGen ExAC TOPMed gnomAD
CA382890525 rs1293684821	135	E>K		No	ClinGen TOPMed
CA6315950 rs775055244	138	T>I		No	ClinGen ExAC TOPMed gnomAD
rs775055244 CA382890614	138	T>N		No	ClinGen ExAC TOPMed gnomAD
rs1592304234 CA382890611	138	T>P		No	ClinGen Ensembl
CA382890666 rs1309476298	140	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA6315951 rs746516183	140	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA382890751 rs1366265292	143	S>P		No	ClinGen TOPMed
CA6315952 rs768224555	146	I>F		No	ClinGen ExAC gnomAD
CA382890898 rs1592304271	147	M>I		No	ClinGen Ensembl
rs368829236 CA229597181	147	M>V		No	ClinGen ESP TOPMed
CA6315953 rs777057755	149	D>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	149	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1225318993 CA382891000	150	D>E		No	ClinGen gnomAD
rs762324269 CA6315954	151	M>V		No	ClinGen ExAC gnomAD
TCGA novel	153	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs201626266 CA6315955	154	P>L		No	ClinGen ExAC TOPMed gnomAD
CA382891148 rs1419874659	155	H>Q		No	ClinGen TOPMed gnomAD
rs1429917297 CA382891156	156	L>F		No	ClinGen gnomAD
rs201410516 CA6315957	157	T>M		No	ClinGen 1000Genomes ESP ExAC TOPMed
rs1354350465 CA382891221	158	V>L		No	ClinGen TOPMed
CA229597239 rs1009261000	160	E>K		No	ClinGen Ensembl
rs1311313732 CA382891349	163	M>I		No	ClinGen TOPMed
CA382891431 rs1302538581	164	V>F		No	ClinGen TOPMed gnomAD
rs1306929462 CA382891437	165	S>T		No	ClinGen TOPMed gnomAD
rs777601667 CA6315973	167	N>K		No	ClinGen ExAC gnomAD
rs942021977 CA229597420	171	S>I		No	ClinGen Ensembl
CA382891548 rs1235117327	171	S>R		No	ClinGen TOPMed
CA6315976 rs771263731	173	K>N		No	ClinGen ExAC gnomAD
rs1343282291 CA382891645	174	Q>E		No	ClinGen TOPMed
CA6315978 rs759849467	176	V>L		No	ClinGen ExAC gnomAD
rs545137934 CA6315980	180	L>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	181	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6316003 rs373868091	181	V>M		No	ClinGen ESP ExAC gnomAD
rs751328446 CA6316005	184	I>L		No	ClinGen ExAC gnomAD
TCGA novel	185	L>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6316009 rs759467898	186	T>M		No	ClinGen ExAC TOPMed gnomAD
rs1285427567 CA382892319	188	L>Q		No	ClinGen TOPMed
rs1224792047 CA382892329	189	G>S		No	ClinGen gnomAD
rs1316919603 CA382892406	191	M>T		No	ClinGen gnomAD
CA229597716 rs141832911	192	S>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs141832911 CA6316012	192	S>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs772632416 CA6316015	195	H>D		No	ClinGen ExAC gnomAD
rs151176056 CA6316016	196	T>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs768734717 CA6316018	197	R>M		No	ClinGen ExAC gnomAD
rs1191585786 CA382892571	198	T>A		No	ClinGen TOPMed gnomAD
CA6316020 rs776608146	201	L>R		No	ClinGen ExAC gnomAD
CA382892644 rs1167569024	202	S>P		No	ClinGen gnomAD
rs1405325729 CA382892678	203	G>C		No	ClinGen gnomAD
rs774335112 CA6316024	204	G>R		No	ClinGen ExAC gnomAD
CA6316026 rs201318219	208	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
CA6316027 rs752285981	210	A>P		No	ClinGen ExAC gnomAD
rs575247461 CA6316031	212	A>S		No	ClinGen 1000Genomes ExAC gnomAD
rs575247461 CA6316030	212	A>T		No	ClinGen 1000Genomes ExAC gnomAD
rs758779632 CA6316034	214	E>G		No	ClinGen ExAC gnomAD
CA6316035 rs780589874	219	P>R		No	ClinGen ExAC gnomAD
rs768732954 CA6316037	221	V>I		No	ClinGen ExAC gnomAD
rs1472703500 CA382893452	226	E>K		No	ClinGen TOPMed gnomAD
rs769978545 CA6316040	227	P>A		No	ClinGen ExAC gnomAD
rs769978545 CA382893476	227	P>T		No	ClinGen ExAC gnomAD
rs1418335384 CA382893517	228	T>A		No	ClinGen gnomAD
rs1407979358 CA382894994	229	S>R		No	ClinGen gnomAD
rs773566111 CA229598883	231	L>V		No	ClinGen Ensembl
CA382895143 rs1444271674	233	S>G		No	ClinGen gnomAD
rs202183518 CA6316061	234	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA382895399 rs775457212	240	V>L		No	ClinGen ExAC gnomAD
rs775457212 CA6316062	240	V>M		No	ClinGen ExAC gnomAD
CA382895432 rs1273083359	241	S>Y		No	ClinGen gnomAD
CA382895447 rs1204493323	242	L>F		No	ClinGen gnomAD
CA382895538 rs1456745292	244	K>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs990707876 CA229598895	245	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA382895781 rs1195565008	250	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1250368527 CA382895798	251	R>C		No	ClinGen gnomAD
CA382895833 rs1251937763	251	R>H		No	ClinGen TOPMed gnomAD
rs776089802 CA6316065	252	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1183376841 CA382895890	253	I>F		No	ClinGen TOPMed gnomAD
CA6316067 rs137886209	253	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1319636489 CA382895909	253	I>T		No	ClinGen TOPMed
rs1183376841 CA382895873	253	I>V		No	ClinGen TOPMed gnomAD
CA382896113 rs1479925491	258	H>Q		No	ClinGen gnomAD
CA382896219 rs1432047991	261	S>I		No	ClinGen TOPMed
rs1176762189 CA382896247	263	K>E		No	ClinGen gnomAD
rs374389742 CA6316068	264	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs1172705010 CA382896326	265	F>S		No	ClinGen gnomAD
rs1397130905 CA382896379	268	F>V		No	ClinGen gnomAD
TCGA novel	269	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA229599001 rs1002065770	273	I>T		No	ClinGen TOPMed
rs774666899 CA6316091	273	I>V		No	ClinGen ExAC gnomAD
rs1484701613 CA382896634	278	Q>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA229599018 rs986593942	282	K>R		No	ClinGen Ensembl
CA6316094 rs753076717	283	G>C		No	ClinGen ExAC gnomAD
CA6316096 rs764288490	284	V>M		No	ClinGen ExAC gnomAD
CA6316100 rs746879394	286	T>N		No	ClinGen ExAC gnomAD
CA6316099 rs779072546	286	T>P		No	ClinGen ExAC TOPMed gnomAD
rs1358661552 CA382896881	287	N>S		No	ClinGen gnomAD
CA229599069 rs752353129	290	P>L		No	ClinGen Ensembl
rs1453112230 CA382896934	290	P>S		No	ClinGen gnomAD
CA6316101 rs754911669	291	Y>C		No	ClinGen ExAC gnomAD
CA382896954 rs1364338265	291	Y>H		No	ClinGen gnomAD
rs369406470 CA6316104	296	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1565815160 CA382897085	297	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA6316106 rs748966571	301	T>P		No	ClinGen ExAC gnomAD
rs1214429256 CA382897219	302	Y>F		No	ClinGen gnomAD
rs1592306242 CA382897243	303	H>P		No	ClinGen Ensembl
rs770520477 CA6316108	305	P>L		No	ClinGen ExAC gnomAD
TCGA novel	306	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA229599334 rs993321162	311	E>K		No	ClinGen TOPMed
CA229599353 rs200654761	313	A>P		No	ClinGen ExAC TOPMed gnomAD
rs200654761 CA6316129	313	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1156740857 CA382897798	315	G>A		No	ClinGen gnomAD
rs1410189384 CA382897810	316	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1479596747 CA382897885	318	G>E		No	ClinGen gnomAD
CA382897913 rs1176027430	319	D>H		No	ClinGen gnomAD
rs138271208 CA6316130	321	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	322	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6316131 rs761184976	323	M>T		No	ClinGen ExAC gnomAD
CA382898081 rs1329889399	325	F>Y		No	ClinGen TOPMed
CA6316133 rs776949339	328	V>M		No	ClinGen ExAC TOPMed gnomAD
CA6316134 rs762213676	330	N>K		No	ClinGen ExAC gnomAD
CA6316138 rs763019179	333	C>S		No	ClinGen ExAC gnomAD
rs763019179 CA6316137	333	C>Y		No	ClinGen ExAC gnomAD
rs201193587 CA6316140	334	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA382898242 rs1205084141	335	M>T		No	ClinGen TOPMed gnomAD
rs763585790 CA229599440	335	M>V		No	ClinGen TOPMed
CA229599446 rs935366483	337	E>D		No	ClinGen Ensembl
CA382898350 rs1489893866	340	S>G		No	ClinGen gnomAD
CA229599447 rs1056913805	341	S>N		No	ClinGen Ensembl
CA382898480 rs12271907 CA6316143	345	N>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA382898485 rs1228303791	346	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA6316146 rs370592684	347	V>F		No	ClinGen ExAC TOPMed gnomAD
rs370592684 CA6316145	347	V>I		No	ClinGen ExAC TOPMed gnomAD
CA6316147 rs143133021	348	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs958235063 CA229599480	351	C>W		No	ClinGen TOPMed
CA6316148 rs35060365 RCV000959236 VAR_048141	352	P>L		No	ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA6316149 rs746561710	353	P>T		No	ClinGen ExAC gnomAD
CA382898622 rs1410854023	354	C>F		No	ClinGen gnomAD
CA382898647 rs1173227072	355	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs769128490 CA6316150	356	P>L		No	ClinGen ExAC TOPMed gnomAD
rs868434734 CA229600619	357	E>G		No	ClinGen gnomAD
CA382900282 rs1278975696	360	P>L		No	ClinGen TOPMed gnomAD
CA382900288 rs1278975696	360	P>R		No	ClinGen TOPMed gnomAD
CA6316182 rs765259348	360	P>S		No	ClinGen ExAC gnomAD
CA6316183 rs151021657	361	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs758270241 CA6316184	363	S>R		No	ClinGen ExAC gnomAD
rs1592307614 CA382900410	365	T>P		No	ClinGen Ensembl
rs1353875618 CA382900537	369	S>N		No	ClinGen gnomAD
CA382900563 rs1592307635	370	T>P		No	ClinGen Ensembl
CA6316185 rs766009741	373	Q>*		No	ClinGen ExAC gnomAD
CA382900627 rs1592307652	374	F>Y		No	ClinGen Ensembl
rs754425127 CA6316187	377	L>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	380	R>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA382900745 rs1592307668	381	T>P		No	ClinGen Ensembl
rs1250189690 CA382900794	382	F>L		No	ClinGen TOPMed
CA382900814 rs1482405501	383	L>P		No	ClinGen TOPMed gnomAD
rs1362658862 CA382900843	385	I>V		No	ClinGen gnomAD
CA382900889 rs1470324875	388	D>N		No	ClinGen gnomAD
rs905395186	389	T>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs139556601 CA6316189	389	T>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6316236 rs780071418	392	T>N		No	ClinGen ExAC gnomAD
rs768567393 CA382901171	393	H>Q		No	ClinGen ExAC gnomAD
CA6316237 rs747267202	393	H>Y		No	ClinGen ExAC gnomAD
rs149710791 CA6316241	395	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA6316240 rs748264266	395	R>W		No	ClinGen ExAC gnomAD
rs988866584 CA229600983	396	F>L		No	ClinGen TOPMed
rs774334992 CA6316243	396	F>Y		No	ClinGen ExAC TOPMed gnomAD
rs759324902 CA6316244	400	V>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs771908038 CA6316245	401	V>A		No	ClinGen ExAC TOPMed gnomAD
CA6316246 rs774948961	402	I>T		No	ClinGen ExAC TOPMed gnomAD
CA229601034 rs916959660	403	G>A		No	ClinGen Ensembl
CA6316248 rs376407071	404	V>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1314171877 CA382901430	405	L>V		No	ClinGen gnomAD
CA6316250 rs761465370	410	Y>C		No	ClinGen ExAC gnomAD
rs1466124366 CA382901517	412	H>R		No	ClinGen gnomAD
rs1201520852 CA382901528	413	I>V		No	ClinGen gnomAD
rs145359289 CA6316253	415	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs751687769 CA6316255	416	D>N	Variant assessed as Somatic; 4.63e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6316256 rs755194527	418	S>N		No	ClinGen ExAC gnomAD
CA382901620 rs1468632900	420	V>I		No	ClinGen gnomAD
rs1235803642 CA382901647	422	N>D		No	ClinGen TOPMed
rs534751103 CA6316257	422	N>S		No	ClinGen 1000Genomes ExAC gnomAD
CA382901676 rs1360263414	424	T>A		No	ClinGen gnomAD
CA382901674 rs1360263414	424	T>P		No	ClinGen gnomAD
rs368538395 CA382901687	425	G>C		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	425	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs368538395 CA6316259	425	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA6316262 rs745822468	428	F>S		No	ClinGen ExAC gnomAD
CA382901745 rs1055587280	431	M>K		No	ClinGen TOPMed gnomAD
CA382901739 rs1592308152	431	M>L		No	ClinGen Ensembl
CA229601160 rs1055587280	431	M>T		No	ClinGen TOPMed gnomAD
TCGA novel	431	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA382901758 rs1312737791	432	L>V		No	ClinGen gnomAD
rs553162084 CA6316264	435	M>L		No	ClinGen 1000Genomes ExAC gnomAD
rs1182985058 CA382901852	437	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA6316269 rs776492089	438	A>S		No	ClinGen ExAC TOPMed gnomAD
CA6316268 rs776492089	438	A>T	Variant assessed as Somatic; 4.644e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs764852970 CA6316270	441	P>S		No	ClinGen ExAC gnomAD
rs773804988 CA6316271	442	T>A		No	ClinGen ExAC gnomAD
TCGA novel	444	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA382901983 rs1428619949	445	T>S		No	ClinGen gnomAD
rs1348320077 CA382902092	446	F>L		No	ClinGen TOPMed
CA382902096 rs1164337286	447	P>A		No	ClinGen TOPMed
rs757341188 CA6316299	447	P>R		No	ClinGen ExAC gnomAD
TCGA novel	449	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs779974362 CA6316300	450	M>K		No	ClinGen ExAC gnomAD
CA6316301 rs575857582	451	A>S		No	ClinGen 1000Genomes ExAC gnomAD
CA6316302 rs754770221	451	A>V		No	ClinGen ExAC TOPMed gnomAD
CA382902268 rs1592308389	452	V>G		No	ClinGen Ensembl
rs747993546 CA6316304	453	F>L		No	ClinGen ExAC TOPMed gnomAD
rs146420624 CA6316305	454	M>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA229601467 rs967325139	454	M>T		No	ClinGen TOPMed
rs777346454 CA6316306	456	E>D		No	ClinGen ExAC gnomAD
CA382902584 rs1406689468	461	W>C		No	ClinGen gnomAD
rs185176960 CA382902637	462	Y>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs770355800 CA6316309	466	A>V		No	ClinGen ExAC TOPMed gnomAD
CA6316312 rs772386778	469	L>P		No	ClinGen ExAC gnomAD
CA229601556 rs527422682	472	T>S		No	ClinGen Ensembl
CA382903014 rs1267230867	474	A>T		No	ClinGen TOPMed gnomAD
rs1284794075 CA382903051	475	D>G		No	ClinGen gnomAD
rs764288479 CA6316315	476	V>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs747370851 CA6316331	483	P>L		No	ClinGen ExAC TOPMed gnomAD
rs747370851 CA382905135	483	P>Q		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	484	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6316333 rs776862890	486	Y>C		No	ClinGen ExAC gnomAD
rs1194021184 CA382905259	487	C>Y		No	ClinGen Ensembl
rs761972933 CA6316334	490	V>M		No	ClinGen ExAC gnomAD
CA6316335 rs765535350	491	Y>C		No	ClinGen ExAC gnomAD
CA382905446 rs1344960192	492	W>*		No	ClinGen gnomAD
CA6316336 rs201390504	494	T>M	Variant assessed as Somatic; 4.64e-05 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA382905562 rs1443695664	495	G>S		No	ClinGen gnomAD
CA382905640 rs1250620799	497	P>L		No	ClinGen gnomAD
CA6316339 rs752683213	498	A>T		No	ClinGen ExAC gnomAD
CA6316340 rs755918336	498	A>V		No	ClinGen ExAC
CA382905668 rs1294862376	499	E>K		No	ClinGen TOPMed gnomAD
rs763821200 CA6316341	500	T>P		No	ClinGen ExAC gnomAD
rs753493720 CA6316342	500	T>S		No	ClinGen ExAC gnomAD
CA6316343 rs575096171	502	R>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs374791984 CA229602872	502	R>H		No	ClinGen ESP TOPMed gnomAD
CA6316344 rs778676229	503	F>L		No	ClinGen ExAC gnomAD
CA382905946 rs1367719164	506	F>L		No	ClinGen TOPMed gnomAD
CA382906026 rs1385693209	509	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1333180580 CA382906040	510	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs542544848 CA6316348	511	T>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6316350 rs776828959	512	A>T		No	ClinGen ExAC TOPMed gnomAD
CA6316352 rs769891019	513	T>I		No	ClinGen ExAC gnomAD
CA382906114 rs1565817375	514	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA382906128 rs1167813458	515	L>*		No	ClinGen TOPMed
CA382906146 rs1167813458	515	L>W		No	ClinGen TOPMed
TCGA novel	516	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA382906401 rs775522341	524	I>M		No	ClinGen ExAC TOPMed gnomAD
rs764136296 CA6316358	525	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs957778752 CA229603024	526	A>V		No	ClinGen TOPMed gnomAD
CA382906490 rs1592309580	528	S>P		No	ClinGen Ensembl
CA382906530 rs1275067131	529	N>I		No	ClinGen TOPMed
rs757135248 CA6316360	532	Q>*		No	ClinGen ExAC gnomAD
rs939843093 CA229603038	532	Q>H		No	ClinGen TOPMed
rs1565817582 CA382906694	533	V>M		No	ClinGen Ensembl
CA229603342 rs749795833	534	A>S		No	ClinGen TOPMed
rs749795833 CA229603340	534	A>T		No	ClinGen TOPMed
CA382906732 rs1305022188	535	T>S		No	ClinGen TOPMed
rs781482503 CA6316384	536	F>V		No	ClinGen ExAC gnomAD
CA6316385 rs753258657	537	V>M		No	ClinGen ExAC gnomAD
rs1180216431 CA382906833	539	P>S		No	ClinGen gnomAD
rs1022932469 CA229603392	542	A>S		No	ClinGen TOPMed gnomAD
rs1022932469 CA382906876	542	A>T		No	ClinGen TOPMed gnomAD
CA229603406 rs970137459	542	A>V		No	ClinGen TOPMed
rs1166512830 CA382906881	543	I>L		No	ClinGen gnomAD
CA382906933 rs1300804645	546	L>I		No	ClinGen gnomAD
CA229603412 rs796568349	550	G>S		No	ClinGen gnomAD
rs1391503054 CA382907006	551	F>L		No	ClinGen gnomAD
CA6316391 rs745931400	554	S>G		No	ClinGen ExAC gnomAD
TCGA novel	556	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1396091218 CA382907222	560	T>A		No	ClinGen gnomAD
rs1371863138 CA382907311	563	Q>*		No	ClinGen gnomAD
rs933263501 CA229603430	565	S>N		No	ClinGen Ensembl
rs772198391 CA382907440	565	S>R		No	ClinGen ExAC TOPMed gnomAD
CA382907457 rs1348164599	567	Y>H		No	ClinGen gnomAD
CA6316393 rs150237922	570	Y>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	570	Y>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	571	V>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	571	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6316414 rs749012531	572	R>S		No	ClinGen ExAC gnomAD
rs909302974 CA229603705	574	G>R		No	ClinGen Ensembl
rs963524374 CA229603726	576	E>Q		No	ClinGen Ensembl
rs1565817876 CA382907856	577	G>D		No	ClinGen Ensembl
rs773823706 CA382907870	578	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6316416 rs773823706	578	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1368207364 CA382907967	581	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA6316417 rs763753494	582	I>*		No	ClinGen ExAC gnomAD
CA382908019 rs1308329431	583	Y>C		No	ClinGen gnomAD
rs767118091 CA6316419	584	G>D		No	ClinGen ExAC gnomAD
CA229603768 rs971853284	586	E>Q		No	ClinGen Ensembl
rs760323610 CA382908101	587	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA6316421 rs760323610	587	R>G		No	ClinGen ExAC gnomAD
rs764693748 CA6316422	587	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA382908165 rs1592310106	589	D>A		No	ClinGen Ensembl
rs754402031 CA6316424	590	L>M		No	ClinGen ExAC gnomAD
CA382908224 rs1229221738	591	T>R		No	ClinGen gnomAD
rs919131196 CA229603838	592	C>R		No	ClinGen gnomAD
CA229603839 rs1043505078	593	L>*		No	ClinGen TOPMed gnomAD
rs765658479 CA6316427	596	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6316428 rs750791458	596	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs765658479 CA382908366	596	R>S		No	ClinGen ExAC TOPMed gnomAD
CA6316429 rs571213849	598	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs200842214 CA382908466	600	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs777625706 CA6316434	600	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs200842214 CA6316433	600	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs749242753 CA382908505	601	E>D		No	ClinGen ExAC TOPMed gnomAD
rs1233138623 CA382908572	604	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs575133154 CA6316436	604	S>R		No	ClinGen 1000Genomes ExAC gnomAD
rs774166783 CA6316437	605	I>L		No	ClinGen ExAC TOPMed gnomAD
rs1442816279 CA382908589	605	I>N		No	ClinGen gnomAD
rs774166783 CA382908582	605	I>V		No	ClinGen ExAC TOPMed gnomAD
CA6316438 rs745702387	607	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6316439 rs771746468	607	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6316440 rs775075804	608	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6316443 rs777230608	610	D>N		No	ClinGen ExAC gnomAD
CA229603994 rs910178934	612	E>G		No	ClinGen gnomAD
rs1290831780 CA382908786	613	D>V		No	ClinGen gnomAD
rs868795453 CA229604002	614	A>S		No	ClinGen Ensembl
CA6316444 rs762376380	616	L>V		No	ClinGen ExAC gnomAD
rs1429776326 CA382908987	618	M>T		No	ClinGen TOPMed gnomAD
CA382909079 rs1300186022	620	F>L		No	ClinGen TOPMed
rs750782915 CA6316448	621	L>M		No	ClinGen ExAC gnomAD
CA382909265 rs1243389094	626	F>L		No	ClinGen gnomAD
rs1471512431 CA382909308	627	F>S		No	ClinGen gnomAD
rs536060950 CA6316449	628	L>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs781278864 CA6316453	630	L>V		No	ClinGen ExAC gnomAD
rs752815717 CA382909435	631	R>G		No	ClinGen ExAC TOPMed gnomAD
CA382909437 rs1320169801	631	R>Q		No	ClinGen gnomAD
rs752815717 CA6316454	631	R>W		No	ClinGen ExAC TOPMed gnomAD
rs745672117 CA6316457	634	A>V		No	ClinGen ExAC gnomAD
CA382909521 rs1592310320	635	Y>S		No	ClinGen Ensembl
CA6316459 rs779702795	639	R>C		No	ClinGen ExAC gnomAD
CA6316460 rs746685392	639	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6316461 rs768243617	641	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1211180265 CA382909655	641	R>W		No	ClinGen TOPMed gnomAD
TCGA novel	642	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6316462 rs147493505	643	K>Q		No	ClinGen ESP ExAC gnomAD
CA382909774 rs1186148458	645	E>K		No	ClinGen gnomAD
CA382909846 rs1264244876	647	R>Q		No	ClinGen TOPMed

No associated diseases with Q9H172

5 regional properties for Q9H172

Type	Name	Position	InterPro Accession
domain	ABC transporter-like, ATP-binding domain	61 - 301	IPR003439
domain	AAA+ ATPase domain	94 - 285	IPR003593
domain	ABC-2 type transporter, transmembrane domain	372 - 581	IPR013525
conserved_site	ABC transporter-like, conserved site	201 - 215	IPR017871
domain	ABC transporter family G domain	258 - 316	IPR043926

Functions

		Description
EC Number
Subcellular Localization	Cell membrane ; Multi-pass membrane protein Cytoplasmic vesicle membrane ; Multi-pass membrane protein Endosome membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

5 GO annotations of cellular component

Name	Definition
cytoplasmic vesicle	A vesicle found in the cytoplasm of a cell.
endosome membrane	The lipid bilayer surrounding an endosome.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

7 GO annotations of molecular function

Name	Definition
ABC-type sterol transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out).
ATP binding	Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity	Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
ATPase-coupled transmembrane transporter activity	Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.
identical protein binding	Binding to an identical protein or proteins.
protein heterodimerization activity	Binding to a nonidentical protein to form a heterodimer.
protein homodimerization activity	Binding to an identical protein to form a homodimer.

8 GO annotations of biological process

Name	Definition
cellular response to high density lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.
cellular response to leukemia inhibitory factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
cholesterol efflux	The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
cholesterol homeostasis	Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
positive regulation of cholesterol biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
positive regulation of cholesterol efflux	Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
regulation of DNA-templated transcription	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
transmembrane transport	The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

10 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P45844	ABCG1	ATP-binding cassette sub-family G member 1	Homo sapiens (Human)	PR
Q99PE8	Abcg5	ATP-binding cassette sub-family G member 5	Mus musculus (Mouse)	PR
Q64343	Abcg1	ATP-binding cassette sub-family G member 1	Mus musculus (Mouse)	PR
Q99PE7	Abcg5	ATP-binding cassette sub-family G member 5	Rattus norvegicus (Rat)	PR
Q09466	wht-3	ABC transporter ATP-binding protein/permease wht-3	Caenorhabditis elegans	PR
Q11180	wht-1	ABC transporter ATP-binding protein/permease wht-1	Caenorhabditis elegans	PR
Q9MAG3	ABCG24	ABC transporter G family member 24	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9M2V6	ABCG17	ABC transporter G family member 17	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9MAH4	ABCG10	ABC transporter G family member 10	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SZR9	ABCG9	ABC transporter G family member 9	Arabidopsis thaliana (Mouse-ear cress)	PR

10	20	30	40	50	60
MAEKALEAVG	CGLGPGAVAM	AVTLEDGAEP	PVLTTHLKKV	ENHITEAQRF	SHLPKRSAVD
70	80	90	100	110	120
IEFVELSYSV	REGPCWRKRG	YKTLLKCLSG	KFCRRELIGI	MGPSGAGKST	FMNILAGYRE
130	140	150	160	170	180
SGMKGQILVN	GRPRELRTFR	KMSCYIMQDD	MLLPHLTVLE	AMMVSANLKL	SEKQEVKKEL
190	200	210	220	230	240
VTEILTALGL	MSCSHTRTAL	LSGGQRKRLA	IALELVNNPP	VMFFDEPTSG	LDSASCFQVV
250	260	270	280	290	300
SLMKSLAQGG	RTIICTIHQP	SAKLFEMFDK	LYILSQGQCI	FKGVVTNLIP	YLKGLGLHCP
310	320	330	340	350	360
TYHNPADFII	EVASGEYGDL	NPMLFRAVQN	GLCAMAEKKS	SPEKNEVPAP	CPPCPPEVDP
370	380	390	400	410	420
IESHTFATST	LTQFCILFKR	TFLSILRDTV	LTHLRFMSHV	VIGVLIGLLY	LHIGDDASKV
430	440	450	460	470	480
FNNTGCLFFS	MLFLMFAALM	PTVLTFPLEM	AVFMREHLNY	WYSLKAYYLA	KTMADVPFQV
490	500	510	520	530	540
VCPVVYCSIV	YWMTGQPAET	SRFLLFSALA	TATALVAQSL	GLLIGAASNS	LQVATFVGPV
550	560	570	580	590	600
TAIPVLLFSG	FFVSFKTIPT	YLQWSSYLSY	VRYGFEGVIL	TIYGMERGDL	TCLEERCPFR
610	620	630	640
EPQSILRALD	VEDAKLYMDF	LVLGIFFLAL	RLLAYLVLRY	RVKSER