Q9M2V6
PR
Gene name |
ABCG17 (WBC17, At3g55100, T15C9.100) |
Protein name |
ABC transporter G family member 17 |
Names |
ABC transporter ABCG.17, AtABCG17, Probable white-brown complex homolog protein 17, AtWBC17 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G55100 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9M2V6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9M2V6-F1 | Predicted | AlphaFoldDB |
77 variants for Q9M2V6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_20422294_G_A,T | 16 | P>L | No | 1000Genomes | |
| tmp_3_20422294_G_A,T | 16 | P>Q | No | 1000Genomes | |
| ENSVATH12767864 | 22 | L>I | No | 1000Genomes | |
| tmp_3_20422274_C_T | 23 | A>T | No | 1000Genomes | |
| tmp_3_20422235_G_A | 36 | R>C | No | 1000Genomes | |
| ENSVATH02506747 | 44 | S>C | No | 1000Genomes | |
| ENSVATH06317731 | 44 | S>N | No | 1000Genomes | |
| ENSVATH00420201 | 50 | T>K | No | 1000Genomes | |
| ENSVATH12767862 | 55 | I>F | No | 1000Genomes | |
| tmp_3_20422121_C_T | 74 | G>R | No | 1000Genomes | |
| ENSVATH00420199 | 77 | T>P | No | 1000Genomes | |
| tmp_3_20422109_G_C | 78 | L>V | No | 1000Genomes | |
| ENSVATH06317730 | 100 | E>V | No | 1000Genomes | |
| tmp_3_20422021_A_C | 107 | L>W | No | 1000Genomes | |
| tmp_3_20421992_C_T | 117 | E>K | No | 1000Genomes | |
| tmp_3_20421983_G_T | 120 | L>I | No | 1000Genomes | |
| ENSVATH06317727 | 127 | E>K | No | 1000Genomes | |
| ENSVATH02506739 | 144 | K>R | No | 1000Genomes | |
| tmp_3_20421884_T_G | 153 | T>P | No | 1000Genomes | |
| ENSVATH00420196 | 157 | Q>H | No | 1000Genomes | |
| tmp_3_20421857_T_C | 162 | T>A | No | 1000Genomes | |
| ENSVATH02506738 | 166 | T>S | No | 1000Genomes | |
| tmp_3_20421815_C_T | 176 | V>I | No | 1000Genomes | |
| ENSVATH02506736 | 181 | R>K | No | 1000Genomes | |
| tmp_3_20421794_G_A | 183 | R>C | No | 1000Genomes | |
| tmp_3_20421773_T_A | 190 | I>F | No | 1000Genomes | |
| ENSVATH02506730 | 200 | D>E | No | 1000Genomes | |
| ENSVATH12767861 | 213 | M>L | No | 1000Genomes | |
| tmp_3_20421638_G_A | 235 | P>S | No | 1000Genomes | |
| tmp_3_20421601_A_T | 247 | I>N | No | 1000Genomes | |
| ENSVATH06317725 | 258 | D>A | No | 1000Genomes | |
| ENSVATH06317724 | 259 | S>F | No | 1000Genomes | |
| ENSVATH12767860 | 264 | P>A | No | 1000Genomes | |
| ENSVATH02506727 | 265 | L>M | No | 1000Genomes | |
| tmp_3_20421482_G_T | 287 | L>I | No | 1000Genomes | |
| tmp_3_20421457_G_A | 295 | P>L | No | 1000Genomes | |
| tmp_3_20421412_T_C | 310 | H>R | No | 1000Genomes | |
| tmp_3_20421392_G_A | 317 | Q>* | No | 1000Genomes | |
| tmp_3_20421359_C_T | 328 | E>K | No | 1000Genomes | |
| ENSVATH12767857 | 336 | R>G | No | 1000Genomes | |
| tmp_3_20421316_G_A | 342 | T>I | No | 1000Genomes | |
| tmp_3_20421304_G_T | 346 | S>Y | No | 1000Genomes | |
| tmp_3_20421263_T_A | 360 | I>F | No | 1000Genomes | |
| ENSVATH14436741 | 362 | A>V | No | 1000Genomes | |
| tmp_3_20421203_C_A | 380 | V>F | No | 1000Genomes | |
| ENSVATH00420194 | 388 | F>Y | No | 1000Genomes | |
| tmp_3_20421176_G_A | 389 | L>F | No | 1000Genomes | |
| tmp_3_20421169_G_T | 391 | A>D | No | 1000Genomes | |
| ENSVATH06317721 | 394 | Y>H | No | 1000Genomes | |
| tmp_3_20421158_A_T | 395 | W>R | No | 1000Genomes | |
| tmp_3_20421130_A_G | 404 | V>A | No | 1000Genomes | |
| tmp_3_20421100_G_A | 414 | A>V | No | 1000Genomes | |
| tmp_3_20421017_G_A | 442 | H>Y | No | 1000Genomes | |
| ENSVATH06317720 | 446 | R>* | No | 1000Genomes | |
| ENSVATH06317719 | 450 | Y>* | No | 1000Genomes | |
| tmp_3_20420990_C_T | 451 | V>I | No | 1000Genomes | |
| ENSVATH06317718 | 458 | T>S | No | 1000Genomes | |
| ENSVATH12767856 | 461 | H>Q | No | 1000Genomes | |
| ENSVATH02506724 | 477 | V>I | No | 1000Genomes | |
| tmp_3_20420834_A_C | 503 | F>V | No | 1000Genomes | |
| ENSVATH12767855 | 507 | V>L | No | 1000Genomes | |
| tmp_3_20420793_C_T | 516 | M>I | No | 1000Genomes | |
| ENSVATH00420192 | 519 | M>I | No | 1000Genomes | |
| tmp_3_20420699_T_C | 548 | I>V | No | 1000Genomes | |
| tmp_3_20420642_C_T | 567 | D>N | No | 1000Genomes | |
| ENSVATH06317716 | 568 | D>N | No | 1000Genomes | |
| tmp_3_20420609_G_T | 578 | Q>K | No | 1000Genomes | |
| ENSVATH06317715 | 580 | F>S | No | 1000Genomes | |
| ENSVATH06317714 | 583 | T>I | No | 1000Genomes | |
| tmp_3_20420551_A_C | 597 | L>R | No | 1000Genomes | |
| tmp_3_20420537_C_T | 602 | G>S | No | 1000Genomes | |
| ENSVATH02506721 | 612 | T>K | No | 1000Genomes | |
| tmp_3_20420480_G_T | 621 | L>I | No | 1000Genomes | |
| ENSVATH02506720 | 634 | C>S | No | 1000Genomes | |
| ENSVATH14436739 | 636 | W>C | No | 1000Genomes | |
| tmp_3_20420423_C_T | 640 | A>T | No | 1000Genomes | |
| ENSVATH06317712 | 663 | A>L | No | 1000Genomes |
No associated diseases with Q9M2V6
4 regional properties for Q9M2V6
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATPase-coupled transmembrane transporter activity | Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
15 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P45844 | ABCG1 | ATP-binding cassette sub-family G member 1 | Homo sapiens (Human) | PR |
| Q9H172 | ABCG4 | ATP-binding cassette sub-family G member 4 | Homo sapiens (Human) | PR |
| Q64343 | Abcg1 | ATP-binding cassette sub-family G member 1 | Mus musculus (Mouse) | PR |
| Q99PE8 | Abcg5 | ATP-binding cassette sub-family G member 5 | Mus musculus (Mouse) | PR |
| Q99PE7 | Abcg5 | ATP-binding cassette sub-family G member 5 | Rattus norvegicus (Rat) | PR |
| Q09466 | wht-3 | ABC transporter ATP-binding protein/permease wht-3 | Caenorhabditis elegans | PR |
| Q11180 | wht-1 | ABC transporter ATP-binding protein/permease wht-1 | Caenorhabditis elegans | PR |
| O81016 | ABCG32 | ABC transporter G family member 32 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC81 | ABCG43 | ABC transporter G family member 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LFH0 | ABCG37 | ABC transporter G family member 37 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZUT8 | ABCG33 | ABC transporter G family member 33 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAG3 | ABCG24 | ABC transporter G family member 24 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAH4 | ABCG10 | ABC transporter G family member 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SZR9 | ABCG9 | ABC transporter G family member 9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GZ52 | ABCG30 | ABC transporter G family member 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLQRDAVIDV | DESEIPPIPF | VLAFNDLTYN | VTLQQRFGLR | FGHSPAKIKT | LLNGITGEAK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EGEILAILGA | SGAGKSTLID | ALAGQIAEGS | LKGTVTLNGE | ALQSRLLRVI | SAYVMQEDLL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FPMLTVEETL | MFAAEFRLPR | SLSKSKKRNR | VETLIDQLGL | TTVKNTVIGD | EGHRGVSGGE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RRRVSIGTDI | IHDPIVLFLD | EPTSGLDSTS | AFMVVQVLKK | IARSGSIVIM | SIHQPSGRIM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EFLDRVIVLS | SGQIVFSDSP | ATLPLFFSEF | GSPIPEKENI | AEFTLDLIKD | LEGSPEGTRG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LVEFNRNWQH | RKLRVSQEPH | HNSSSLGEAI | NASISRGKLV | STSYRSIPSY | VNPWWVETVI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LAKRYMINWT | RTPELIGTRV | FIVMMTGFLL | ATVYWKVDDS | PRGVQERLSF | FSFAMATMFY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SCADGLPAFI | QERYIFLRET | AHNAYRRSSY | VISHSLVTLP | HLFALSIGFA | ATTFWFVGLN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GGLAGFIYYL | MIIFASFWSG | CSFVTFVSGV | IPNVMMSYMV | TFGYLSYCLL | FSGFYVNRDR |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IHLYWIWIHY | ISLLKYPYEA | VLHNEFDDPS | RCFVRGNQVF | DNTIMEGVSE | TTKAKLLETM |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SGYLGMELTE | STCLTTGSDL | LKQHGIEQLD | KWGCLWVTLA | WGFFFRILFY | FSLLLGSKNK |
| RA |