Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7PC81

Entry ID Method Resolution Chain Position Source
AF-Q7PC81-F1 Predicted AlphaFoldDB

205 variants for Q7PC81

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_8696681_C_T 2 T>I No 1000Genomes
ENSVATH06673297 6 T>I No 1000Genomes
tmp_4_8696723_A_G 16 N>S No 1000Genomes
ENSVATH02839596 19 N>D No 1000Genomes
tmp_4_8696745_T_A 23 D>E No 1000Genomes
ENSVATH14200706 27 S>P No 1000Genomes
tmp_4_8696762_G_A 29 W>* No 1000Genomes
ENSVATH02839597 30 V>I No 1000Genomes
ENSVATH06673298 31 A>S No 1000Genomes
tmp_4_8696788_T_C 38 C>R No 1000Genomes
ENSVATH02839599 51 E>K No 1000Genomes
ENSVATH02839600 52 Q>K No 1000Genomes
ENSVATH02839601 56 S>C No 1000Genomes
ENSVATH02839602 57 Q>L No 1000Genomes
tmp_4_8696866_T_A 64 S>T No 1000Genomes
ENSVATH02839603 72 R>H No 1000Genomes
ENSVATH02839605 80 R>K No 1000Genomes
ENSVATH00506834 84 D>N No 1000Genomes
ENSVATH11771563 88 V>I No 1000Genomes
ENSVATH06673301 96 R>I No 1000Genomes
ENSVATH06673302 96 R>S No 1000Genomes
ENSVATH02839607 97 T>I No 1000Genomes
ENSVATH02839611 105 P>Q No 1000Genomes
ENSVATH06673307 108 E>K No 1000Genomes
ENSVATH00506835 124 H>Y No 1000Genomes
ENSVATH02839613 132 W>S No 1000Genomes
ENSVATH02839614 138 K>I No 1000Genomes
tmp_4_8697170_A_T 138 K>N No 1000Genomes
ENSVATH02839614 138 K>R No 1000Genomes
ENSVATH14200708 144 F>S No 1000Genomes
tmp_4_8697279_C_G 145 S>* No 1000Genomes
tmp_4_8697336_A_T 164 K>I No 1000Genomes
tmp_4_8697449_A_T 178 T>S No 1000Genomes
tmp_4_8697464_G_C 183 A>P No 1000Genomes
ENSVATH06673317 186 G>E No 1000Genomes
ENSVATH02839620 190 P>L No 1000Genomes
tmp_4_8697485_C_A 190 P>T No 1000Genomes
tmp_4_8697649_G_A 221 D>N No 1000Genomes
ENSVATH02839622 222 L>F No 1000Genomes
ENSVATH00506838 222 L>M No 1000Genomes
ENSVATH11771639 228 S>T No 1000Genomes
tmp_4_8697674_T_C 229 V>A No 1000Genomes
ENSVATH06673321 234 D>E No 1000Genomes
ENSVATH06673322 238 C>Y No 1000Genomes
ENSVATH02839624 243 G>E No 1000Genomes
ENSVATH02839623 243 G>R No 1000Genomes
ENSVATH11771640 245 R>H No 1000Genomes
ENSVATH06673324 245 R>S No 1000Genomes
tmp_4_8697847_G_A 260 G>R No 1000Genomes
tmp_4_8697851_T_A 261 I>K No 1000Genomes
ENSVATH02839628 295 T>N No 1000Genomes
ENSVATH02839631 335 E>* No 1000Genomes
tmp_4_8698372_G_A 342 S>N No 1000Genomes
ENSVATH06673337 381 L>V No 1000Genomes
ENSVATH06673339 398 I>K No 1000Genomes
ENSVATH02839634 398 I>V No 1000Genomes
ENSVATH06673340 401 F>L No 1000Genomes
ENSVATH06673342 408 K>N No 1000Genomes
ENSVATH11771745 408 K>R No 1000Genomes
tmp_4_8698576_C_G 410 P>R No 1000Genomes
ENSVATH00506839 411 Q>K No 1000Genomes
tmp_4_8698590_G_A 415 V>I No 1000Genomes
ENSVATH06673344 417 E>G No 1000Genomes
ENSVATH06673343 417 E>K No 1000Genomes
ENSVATH06673345 421 E>K No 1000Genomes
tmp_4_8698696_G_T 427 D>Y No 1000Genomes
ENSVATH00506840 435 R>I No 1000Genomes
ENSVATH00506840 435 R>K No 1000Genomes
ENSVATH02839635 440 C>S No 1000Genomes
ENSVATH06673348 444 I>N No 1000Genomes
tmp_4_8698750_G_C 445 D>H No 1000Genomes
ENSVATH11771750 452 K>Q No 1000Genomes
ENSVATH14200757 461 Q>* No 1000Genomes
ENSVATH00506841 463 E>K No 1000Genomes
ENSVATH06673349 471 S>Y No 1000Genomes
tmp_4_8698835_C_T 473 T>I No 1000Genomes
ENSVATH00506842 480 I>F No 1000Genomes
ENSVATH06673351 497 R>G No 1000Genomes
tmp_4_8698937_T_C 507 F>S No 1000Genomes
tmp_4_8699054_G_T 520 G>* No 1000Genomes
ENSVATH02839641 543 L>M No 1000Genomes
tmp_4_8699171_C_T 559 P>S No 1000Genomes
ENSVATH02839642 565 V>I No 1000Genomes
tmp_4_8699202_C_T 569 A>V No 1000Genomes
tmp_4_8699244_G_A 583 W>* No 1000Genomes
ENSVATH06673354 591 I>M No 1000Genomes
ENSVATH11771806 603 L>I No 1000Genomes
ENSVATH02839646 622 I>F No 1000Genomes
ENSVATH02839647 625 V>F No 1000Genomes
tmp_4_8699466_G_T 630 A>S No 1000Genomes
ENSVATH11771807 644 A>T No 1000Genomes
ENSVATH02839652 645 V>I No 1000Genomes
ENSVATH02839656 655 I>V No 1000Genomes
tmp_4_8699545_G_A 656 G>E No 1000Genomes
ENSVATH06673358 662 L>F No 1000Genomes
ENSVATH06673359 674 P>S No 1000Genomes
ENSVATH06673362 676 M>K No 1000Genomes
ENSVATH11771809 678 S>F No 1000Genomes
tmp_4_8699697_G_C 682 W>S No 1000Genomes
ENSVATH02839661 698 S>A No 1000Genomes
tmp_4_8699754_T_A 701 F>Y No 1000Genomes
tmp_4_8699763_C_T 704 P>L No 1000Genomes
ENSVATH11771811 705 M>L No 1000Genomes
ENSVATH00506846 705 M>R No 1000Genomes
ENSVATH09576879 707 R>G No 1000Genomes
ENSVATH06673366 709 M>I No 1000Genomes
tmp_4_8699875_C_G 713 N>K No 1000Genomes
tmp_4_8699877_G_A 714 R>K No 1000Genomes
ENSVATH02839665 735 N>K No 1000Genomes
ENSVATH06673368 744 T>A No 1000Genomes
tmp_4_8699969_C_T 745 L>F No 1000Genomes
ENSVATH06673371 787 S>C No 1000Genomes
ENSVATH02839667 789 N>T No 1000Genomes
tmp_4_8700216_T_G 800 F>C No 1000Genomes
tmp_4_8700219_A_C 801 Q>P No 1000Genomes
tmp_4_8700233_T_A 806 F>I No 1000Genomes
tmp_4_8700236_A_G,T 807 I>F No 1000Genomes
ENSVATH00506848 807 I>T No 1000Genomes
tmp_4_8700236_A_G,T 807 I>V No 1000Genomes
ENSVATH02839671 812 G>R No 1000Genomes
tmp_4_8700374_C_T 819 S>F No 1000Genomes
ENSVATH02839673 834 M>V No 1000Genomes
ENSVATH06673375 838 G>S No 1000Genomes
ENSVATH11771951 839 A>T No 1000Genomes
ENSVATH06673376 846 D>N No 1000Genomes
ENSVATH14200762 849 S>L No 1000Genomes
ENSVATH14200763 854 R>H No 1000Genomes
tmp_4_8700485_A_C 856 D>A No 1000Genomes
tmp_4_8700487_A_G 857 I>V No 1000Genomes
ENSVATH02839675 860 Q>K No 1000Genomes
ENSVATH02839677 867 V>L No 1000Genomes
ENSVATH11771952 884 D>E No 1000Genomes
tmp_4_8700588_A_C 890 L>F No 1000Genomes
tmp_4_8700748_G_C 915 A>P No 1000Genomes
ENSVATH11771953 919 E>Q No 1000Genomes
ENSVATH06673384 920 V>F No 1000Genomes
ENSVATH06673384 920 V>I No 1000Genomes
ENSVATH14200805 926 L>P No 1000Genomes
ENSVATH06673385 933 L>I No 1000Genomes
ENSVATH00506850 942 V>L No 1000Genomes
ENSVATH06673387 944 A>P No 1000Genomes
tmp_4_8700844_C_T 947 R>C No 1000Genomes
ENSVATH06673389 948 K>E No 1000Genomes
tmp_4_8700848_A_G 948 K>R No 1000Genomes
ENSVATH11771954 954 V>A No 1000Genomes
ENSVATH11772047 991 G>D No 1000Genomes
ENSVATH06673391 1003 I>V No 1000Genomes
ENSVATH14200808 1012 L>M No 1000Genomes
ENSVATH11772051 1025 G>R No 1000Genomes
tmp_4_8701189_A_G 1036 E>G No 1000Genomes
ENSVATH02839684 1038 F>L No 1000Genomes
tmp_4_8701286_C_G 1040 S>R No 1000Genomes
ENSVATH06673394 1042 P>H No 1000Genomes
ENSVATH14200809 1048 K>T No 1000Genomes
ENSVATH06673395 1051 S>F No 1000Genomes
tmp_4_8701364_A_C 1066 E>D No 1000Genomes
tmp_4_8701378_T_G 1071 V>G No 1000Genomes
tmp_4_8701380_G_T 1072 D>Y No 1000Genomes
tmp_4_8701399_A_C 1078 E>A No 1000Genomes
ENSVATH11772105 1080 S>A No 1000Genomes
ENSVATH06673397 1089 V>G No 1000Genomes
ENSVATH06673398 1092 Q>K No 1000Genomes
tmp_4_8701638_A_C 1135 N>H No 1000Genomes
ENSVATH02839687 1139 I>N No 1000Genomes
ENSVATH06673403 1154 L>W No 1000Genomes
ENSVATH06673411 1163 Q>* No 1000Genomes
tmp_4_8701902_T_G 1188 V>G No 1000Genomes
tmp_4_8701907_T_A 1190 F>I No 1000Genomes
ENSVATH02839692 1196 R>* No 1000Genomes
ENSVATH14200812 1196 R>Q No 1000Genomes
ENSVATH06673414 1206 R>H No 1000Genomes
ENSVATH06673414 1206 R>L No 1000Genomes
ENSVATH14200813 1207 M>I No 1000Genomes
ENSVATH02839693 1210 P>S No 1000Genomes
ENSVATH06673415 1211 W>* No 1000Genomes
tmp_4_8701970_T_G 1211 W>G No 1000Genomes
tmp_4_8701982_C_A 1215 L>I No 1000Genomes
ENSVATH06673417 1219 L>F No 1000Genomes
ENSVATH06673416 1219 L>V No 1000Genomes
tmp_4_8702096_T_C 1224 Y>H No 1000Genomes
ENSVATH02839696 1231 I>V No 1000Genomes
ENSVATH06673418 1233 V>L No 1000Genomes
tmp_4_8702129_A_T 1235 I>F No 1000Genomes
ENSVATH06673419 1238 P>A No 1000Genomes
ENSVATH06673420 1243 H>Q No 1000Genomes
ENSVATH02839697 1247 Y>F No 1000Genomes
tmp_4_8702175_T_G 1250 F>C No 1000Genomes
tmp_4_8702179_G_T 1251 W>C No 1000Genomes
ENSVATH06673422 1271 V>I No 1000Genomes
tmp_4_8702255_G_A 1277 V>I No 1000Genomes
tmp_4_8702518_A_T 1322 N>Y No 1000Genomes
ENSVATH14200838 1332 M>I No 1000Genomes
ENSVATH06673431 1333 E>G No 1000Genomes
ENSVATH11772113 1347 A>D No 1000Genomes
tmp_4_8702593_G_A 1347 A>T No 1000Genomes
tmp_4_8702638_CT_TT,C 1362 L>F No 1000Genomes
tmp_4_8702664_C_A 1370 F>L No 1000Genomes
ENSVATH06673434 1374 L>F No 1000Genomes
ENSVATH14200839 1376 S>Y No 1000Genomes
tmp_4_8702683_C_G 1377 L>V No 1000Genomes
tmp_4_8702690_C_T 1379 A>V No 1000Genomes
tmp_4_8702692_T_G 1380 F>V No 1000Genomes
tmp_4_8702693_TC_AC,T 1380 F>Y No 1000Genomes
tmp_4_8702706_A_T 1384 K>N No 1000Genomes
ENSVATH02839705 1386 N>K No 1000Genomes

No associated diseases with Q7PC81

9 regional properties for Q7PC81

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 137 - 411 IPR003439-1
domain ABC transporter-like, ATP-binding domain 798 - 1043 IPR003439-2
domain AAA+ ATPase domain 163 - 388 IPR003593-1
domain AAA+ ATPase domain 827 - 1019 IPR003593-2
domain ABC-2 type transporter, transmembrane domain 491 - 701 IPR013525-1
domain ABC-2 type transporter, transmembrane domain 1115 - 1328 IPR013525-2
domain Plant PDR ABC transporter associated 706 - 768 IPR013581
domain ATP-binding cassette transporter, PDR-like subfamily G, domain 2 795 - 1025 IPR034003
domain ABC transporter family G domain 999 - 1061 IPR043926

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
ABC-type transporter activity Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

14 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q08409 AUS1 ATP-dependent permease AUS1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P40550 PDR11 ATP-dependent permease PDR11 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q8GU92 ABCG35 ABC transporter G family member 35 Oryza sativa subsp japonica (Rice) PR
Q8GU83 ABCG41 ABC transporter G family member 41 Oryza sativa subsp japonica (Rice) PR
Q9M2V6 ABCG17 ABC transporter G family member 17 Arabidopsis thaliana (Mouse-ear cress) PR
O81016 ABCG32 ABC transporter G family member 32 Arabidopsis thaliana (Mouse-ear cress) PR
Q7PC83 ABCG41 ABC transporter G family member 41 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LFH0 ABCG37 ABC transporter G family member 37 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZUT8 ABCG33 ABC transporter G family member 33 Arabidopsis thaliana (Mouse-ear cress) PR
Q9MAH4 ABCG10 ABC transporter G family member 10 Arabidopsis thaliana (Mouse-ear cress) PR
Q9MAG3 ABCG24 ABC transporter G family member 24 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SZR9 ABCG9 ABC transporter G family member 9 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GZ52 ABCG30 ABC transporter G family member 30 Arabidopsis thaliana (Mouse-ear cress) PR
Q7PC82 ABCG42 ABC transporter G family member 42 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MTMPQTDGVE FASRNNLENG DGDQVRSQWV AIERSPTCKR ITTALFCKRD EQGKRSQRRV
70 80 90 100 110 120
MDVSKLEDLD RRLFIDELIR HVEDDNRVLL QKIRTRTDEV GIDLPKIEVR FSDLFVEAEC
130 140 150 160 170 180
EVVHGKPIPT LWNAIASKLS RFTFSKQEDK ISILKGVSGI IRPKRMTLLL GPPGCGKTTL
190 200 210 220 230 240
LLALSGRLDP SLKTRGEVSY NGHLFSEFVP EKTSSYVSQN DLHIPELSVR ETLDFSGCFQ
250 260 270 280 290 300
GAGSRLEMMK EISRREKLKG IVPDPDIDAY MKAASIEGSK TNLQTDYILK ILGLTICADT
310 320 330 340 350 360
RVGDASRPGI SGGQKRRLTT GEMIVGPIKT LFMDEISNGL DSSTTFQILS CLQQFARLSE
370 380 390 400 410 420
GTILVSLLQP APETFELFDD LILMGEGKII YHGPRDFICS FFEDCGFKCP QRKSVAEFLQ
430 440 450 460 470 480
EVISRKDQEQ YWCHRDKPYC YVSIDSFIEK FKKSDLGLQL QDELSKTYDK SQTQKDGLCI
490 500 510 520 530 540
RKYSLSNWDM FKACSRREFL LMKRNSFVYV FKSGLLIFIG SIAMTVYLRT GSTRDSLHAN
550 560 570 580 590 600
YLLGSLFFSL IKLLADGLPE LTLTVSRIAV FCKQKELYFY PAWAYAIPSA ILKIPISFLE
610 620 630 640 650 660
SFLWTMLTYY VIGYSPEAGR FIRQVLILFA LHLSCISMFR AIGAVFRDFD VATTIGSISI
670 680 690 700 710 720
VLLSVFGGFI VRKPSMPSWL EWGFWLSPLS YAEIGLTSNE FFAPMWRKMT SENRTLGEQV
730 740 750 760 770 780
LDARGLNFGN QSYWNAFGAL IGFTLFFNTV FALALTFLKT SQRSRVIVSH DKNTQSSEKD
790 800 810 820 830 840
SKIASHSKNA LPFEPLTFTF QDVQYFIETP QGKKLQLLSD VTGAFKPGVL TALMGVSGAG
850 860 870 880 890 900
KTTLLDVLSG RKTRGDIKGQ IEVGGYVKVQ DTFSRVSGYC EQFDIHSPNL TVQESLKYSA
910 920 930 940 950 960
WLRLPCNISS ETKSAIVNEV LETIELEEIK DSLVGVPGIS GVTAEQRKRL TIAVELVSNP
970 980 990 1000 1010 1020
SIIFMDEPTT GLDARAAAIV MRAVKNIAET GRTVVCTIHQ PSIDIFEAFD ELILMKNGGK
1030 1040 1050 1060 1070 1080
IIYYGPLGQH SSKVIEYFMS IPGVPKLKEN SNPATWILDI TSKSSEDKLG VDLAHIYEES
1090 1100 1110 1120 1130 1140
TLFKENKMVI EQTRCTSLGS ERLILSSRYA QTSWEQFKAC LWKQHLSYWR NPSYNLTRII
1150 1160 1170 1180 1190 1200
FMCFTCMLCG ILFLQKAKEI NNQQDLFNVF GSMFTVVLFS GINNCSTVIF CVATERNVFY
1210 1220 1230 1240 1250 1260
RERFSRMYNP WAYSLAQVLV EIPYSLFQSI IYVIIVYPMV GYHWSVYKVF WSFYSIFCSL
1270 1280 1290 1300 1310 1320
LIFNYFGMLL VVVTPNVHIA FTLRSSFYAI VNLFAGYVMP KPNIPRWWIW MYYLSPTSWV
1330 1340 1350 1360 1370 1380
LNGLLTSQYG DMEKEILAFG EKKKVSAFLE DYFGYRYDSL ALVAVVLIAF PILLASLFAF
FIGKLNFQKK