Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8GU83
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8GU83-F1 | Predicted | AlphaFoldDB |
No variants for Q8GU83
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8GU83 | |||||
No associated diseases with Q8GU83
11 regional properties for Q8GU83
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 159 - 432 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 838 - 1090 | IPR003439-2 |
| domain | AAA+ ATPase domain | 184 - 409 | IPR003593-1 |
| domain | AAA+ ATPase domain | 875 - 1067 | IPR003593-2 |
| domain | ABC-2 type transporter, transmembrane domain | 511 - 722 | IPR013525-1 |
| domain | ABC-2 type transporter, transmembrane domain | 1163 - 1379 | IPR013525-2 |
| domain | Plant PDR ABC transporter associated | 727 - 789 | IPR013581 |
| domain | ABC-transporter, N-terminal domain | 106 - 155 | IPR029481 |
| domain | ATP-binding cassette transporter, PDR-like subfamily G, domain 2 | 835 - 1073 | IPR034003 |
| domain | ABC transporter family G domain | 390 - 446 | IPR043926-1 |
| domain | ABC transporter family G domain | 1047 - 1108 | IPR043926-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08409 | AUS1 | ATP-dependent permease AUS1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P40550 | PDR11 | ATP-dependent permease PDR11 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q8GU92 | ABCG35 | ABC transporter G family member 35 | Oryza sativa subsp japonica (Rice) | PR |
| Q9LFH0 | ABCG37 | ABC transporter G family member 37 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZUT8 | ABCG33 | ABC transporter G family member 33 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC83 | ABCG41 | ABC transporter G family member 41 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC81 | ABCG43 | ABC transporter G family member 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC82 | ABCG42 | ABC transporter G family member 42 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GZ52 | ABCG30 | ABC transporter G family member 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEDKKQQQQQ | QREEAEAEEE | APVVPSSLRA | AATCRSLSSL | SSSLRWDHRG | DDDEEEAELR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WAAIERLPTL | DRMRTSVLSS | EAVDVRRLGA | AQRRVLVERL | VADIQRDNLR | LLRKQRRRME |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RVGVRQPTVE | VRWRNVRVEA | DCQVVSGKPL | PTLLNTVLAT | ARGLSRRPHA | RIPILNDVTG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ILKPSRLTLL | LGPPGCGKTT | LLLALAGKLD | KNLKVTGEVE | YNGANLNTFV | PEKTSAYISQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YDLHVPEMTV | RETLDFSARF | QGVGTRAEIM | KEVIRREKEA | GITPDPDIDT | YMKAISVEGL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ERSMQTDYIM | KIMGLDICAD | IIVGDIMRRG | ISGGEKKRLT | TGEMIVGPSR | ALFMDEISTG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LDSSTTFQIV | SCLQQVAHIS | ESTILVSLLQ | PAPETYDLFD | DIILMAEGKI | VYHGSKSCIM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NFFESCGFKC | PERKGAADFL | QEVLSKKDQQ | QYWSRTEETY | NFVTIDHFCE | KFKASQVGQN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LVEELANPFD | KSEVYNNALS | LNIYSLTKWD | LLKACFAREI | LLMRRNAFIY | ITKVVQLGLL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| AVITGTVFLR | THMGVDRAHA | DYYMGSLFYA | LILLLVNGFP | ELAIAVSRLP | VFYKQRDYYF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| YPAWAYAIPS | FILKIPLSLV | ESITWTSISY | YLIGYTPEAS | RFFCQLLILF | LVHTGALSLF |
| 670 | 680 | 690 | 700 | 710 | 720 |
| RCVASYCQTM | VASSVGGTMS | FLVILLFGGF | IIPRLSMPNW | LKWGFWISPL | SYAEIGLTGN |
| 730 | 740 | 750 | 760 | 770 | 780 |
| EFLAPRWLKT | TTSGVTLGRR | VLMDRGLDFS | SYFYWISASA | LIGFILLLNV | GYAIGLTIKK |
| 790 | 800 | 810 | 820 | 830 | 840 |
| PTGTSRAIIS | RDKFSTFDRR | GKDMSKDMDN | RMPKLQVGNA | LAPNKTGTMV | LPFSPLTISF |
| 850 | 860 | 870 | 880 | 890 | 900 |
| QDVNYYVDTP | VEMREQGYKE | RKLQLLHNIT | GAFQPGVLSA | LMGVTGAGKT | TLLDVLAGRK |
| 910 | 920 | 930 | 940 | 950 | 960 |
| TGGVIEGDIR | VGGYPKIQQT | FARISGYCEQ | TDVHSPQITV | EESVAYSAWL | RLPTEVDSKT |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| RREFVDEVIQ | TIELDDIRDA | LVGLPGVSGL | STEQRKRLTI | AVELVSNPSV | IFMDEPTSGL |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| DARAAAIVMR | AVKNVADTGR | TVVCTIHQPS | IEIFEAFDEL | MLMKRGGELI | YAGPLGLHSC |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| NVIHYFETIP | GVPKIKDNYN | PSTWMLEVTC | ASMEAQLGVD | FAQIYRESTM | CKDKDALVKS |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| LSKPALGTSD | LHFPTRFPQK | FREQLKACIW | KQCLSYWRSP | SYNLVRILFI | TISCIVFGVL |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| FWQQGDINHI | NDQQGLFTIL | GCMYGTTLFT | GINNCQSVIP | FISIERSVVY | RERFAGMYSP |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| WAYSLAQVAM | EIPYVLVQIL | LIMFIAYPMI | GYAWTAAKFF | WFMYTIACTL | LYFLYFGMMI |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| VSLTPNIQVA | SILASMFYTL | QNLMSGFIVP | APQIPRWWIW | LYYTSPLSWT | LNVFFTTQFG |
| 1390 | 1400 | 1410 | 1420 | 1430 | 1440 |
| DEHQKEISVF | GETKSVAAFI | KDYFGFRHDL | LPLAAIILAM | FPILFAILFG | LSISKLNFQR |
| R |