P40550
PR
Gene name |
PDR11 (YIL013C) |
Protein name |
ATP-dependent permease PDR11 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YIL013C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P40550
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P40550-F1 | Predicted | AlphaFoldDB |
14 variants for P40550
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s09-332368 | 25 | E>K | No | SGRP | |
| s09-332290 | 51 | D>N | No | SGRP | |
| s09-332278 | 55 | R>G | No | SGRP | |
| s09-331411 | 344 | E>Q | No | SGRP | |
| s09-331396 | 349 | D>N | No | SGRP | |
| s09-330991 | 484 | F>L | No | SGRP | |
| s09-330931 | 504 | V>I | No | SGRP | |
| s09-330661 | 594 | D>N | No | SGRP | |
| s09-329896 | 849 | V>I | No | SGRP | |
| s09-329863 | 860 | G>R | No | SGRP | |
| s09-329521 | 974 | D>N | No | SGRP | |
| s09-329172 | 1090 | T>I | No | SGRP | |
| s09-328298 | 1381 | K>N | No | SGRP | |
| s09-328212 | 1410 | S>T | No | SGRP |
No associated diseases with P40550
10 regional properties for P40550
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 31 - 273 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 751 - 979 | IPR003439-2 |
| domain | AAA+ ATPase domain | 774 - 955 | IPR003593 |
| domain | CDR ABC transporter | 587 - 658 | IPR010929 |
| domain | ABC-2 type transporter, transmembrane domain | 365 - 575 | IPR013525-1 |
| domain | ABC-2 type transporter, transmembrane domain | 1072 - 1282 | IPR013525-2 |
| conserved_site | ABC transporter-like, conserved site | 172 - 186 | IPR017871 |
| domain | ATP-binding cassette transporter, PDR-like subfamily G, domain 1 | 45 - 255 | IPR034001 |
| domain | ATP-binding cassette transporter, PDR-like subfamily G, domain 2 | 748 - 961 | IPR034003 |
| domain | ABC transporter family G domain | 935 - 994 | IPR043926 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell periphery | The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| sterol import | The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08409 | AUS1 | ATP-dependent permease AUS1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q8GU92 | ABCG35 | ABC transporter G family member 35 | Oryza sativa subsp japonica (Rice) | PR |
| Q8GU83 | ABCG41 | ABC transporter G family member 41 | Oryza sativa subsp japonica (Rice) | PR |
| O81016 | ABCG32 | ABC transporter G family member 32 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC83 | ABCG41 | ABC transporter G family member 41 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LFH0 | ABCG37 | ABC transporter G family member 37 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZUT8 | ABCG33 | ABC transporter G family member 33 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC81 | ABCG43 | ABC transporter G family member 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC82 | ABCG42 | ABC transporter G family member 42 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GZ52 | ABCG30 | ABC transporter G family member 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLSKYFNPI | PDASVTFDGA | TVQLEESLGA | VQNDEESASE | FKNVGHLEIS | DITFRANEGE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VVLVLGNPTS | ALFKGLFHGH | KHLKYSPEGS | IRFKDNEYKQ | FASKCPHQII | YNNEQDIHFP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YLTVEQTIDF | ALSCKFHIPK | QERIEMRDEL | LKEFGLSHVK | KTYVGNDYVR | GVSGGERKRI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SIIETFIANG | SVYLWDNSTK | GLDSATALEF | LSITQKMAKA | TRSVNFVKIS | QASDKIVSKF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DKILMLGDSF | QVFYGTMEEC | LTHFHDTLQI | KKNPNDCIIE | YLTSILNFKF | KETSNSIVGL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DTPSVVSEEN | QALNINNETD | LHTLWIQSPY | YKHWKAITSK | TVQECTRKDV | NPDDISPIFS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IPLKTQLKTC | TVRAFERIIG | DRNYLISQFV | SVVVQSLVIG | SLFYNIPLTT | IGSFSRGSLT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FFSILFFTFL | SLADMPASFQ | RQPVVRKHVQ | LHFYYNWVET | LATNFFDCCS | KFILVVIFTI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ILYFLAHLQY | NAARFFIFLL | FLSVYNFCMV | SLFALTALIA | PTLSMANLLA | GILLLAIAMY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ASYVIYMKDM | HPWFIWIAYL | NPAMFAMEAI | LSNELFNLKL | DCHESIIPRG | EYYDNISFSH |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KACAWQGATL | GNDYVRGRDY | LKSGLKYTYH | HVWRNFGIII | GFLCFFLFCS | LLAAEYITPL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| FTRENLLRWN | NYLKRYCPFL | NSQKKNNKSA | ITNNDGVCTP | KTPIANFSTS | SSSVPSVSHQ |
| 730 | 740 | 750 | 760 | 770 | 780 |
| YDTDYNIKHP | DETVNNHTKE | SVAMETQKHV | ISWKNINYTI | GDKKLINDAS | GYISSGLTAL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| MGESGAGKTT | LLNVLSQRTE | SGVVTGELLI | DGQPLTNIDA | FRRSIGFVQQ | QDVHLELLTV |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RESLEISCVL | RGDGDRDYLG | VVSNLLRLPS | EKLVADLSPT | QRKLLSIGVE | LVTKPSLLLF |
| 910 | 920 | 930 | 940 | 950 | 960 |
| LDEPTSGLDA | EAALTIVQFL | KKLSMQGQAI | LCTIHQPSKS | VISYFDNIYL | LKRGGECVYF |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| GSLPNACDYF | VAHDRRLTFD | REMDNPADFV | IDVVGSGSTN | IPMDDAEKPT | SSKIDEPVSY |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| HKQSDSINWA | ELWQSSPEKV | RVADDLLLLE | EEARKSGVDF | TTSVWSPPSY | MEQIKLITKR |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| QYICTKRDMT | YVFAKYALNA | GAGLFIGFSF | WRTKHNINGL | QDAIFLCFMM | LCVSSPLINQ |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| VQDKALQSKE | VYIAREARSN | TYHWTVLLIA | QTIVELPLAI | SSSTLFFLCC | YFCCGFETSA |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| RVAGVFYLNY | ILFSMYYLSF | GLWLLYSAPD | LQTAAVFVAF | LYSFTASFCG | VMQPYSLFPR |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| FWTFMYRVSP | YTYFIETFVS | LLLHDREVNC | STSEMVPSQP | VMGQTCGQFM | KPFIDEFGGK |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| LHINNTYTVC | AYCMYTVGDD | FLAQENMSYH | HRWRNFGFEW | VFVCFNIAAM | FVGFYLTYIK |
| 1390 | 1400 | 1410 | |||
| KIWPSVIDGI | KKCIPSMRRS | KTSHNPNEQS | V |