Q7PC82
PR
Gene name |
ABCG42 (PDR14, At4g15233, FCAALL.460) |
Protein name |
ABC transporter G family member 42 |
Names |
ABC transporter ABCG.42, AtABCG42, Pleiotropic drug resistance protein 14 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G15233 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7PC82
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7PC82-F1 | Predicted | AlphaFoldDB |
163 variants for Q7PC82
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_8688325_A_T | 2 | T>S | No | 1000Genomes | |
| tmp_4_8688341_A_G | 7 | D>G | No | 1000Genomes | |
| tmp_4_8688340_G_A | 7 | D>N | No | 1000Genomes | |
| tmp_4_8688355_G_T | 12 | A>S | No | 1000Genomes | |
| ENSVATH02839427 | 16 | T>N | No | 1000Genomes | |
| ENSVATH02839428 | 17 | N>T | No | 1000Genomes | |
| tmp_4_8688373_G_A | 18 | E>K | No | 1000Genomes | |
| ENSVATH14200518 | 24 | D>N | No | 1000Genomes | |
| ENSVATH14200519 | 24 | D>V | No | 1000Genomes | |
| tmp_4_8688414_G_C | 31 | W>C | No | 1000Genomes | |
| ENSVATH02839429 | 32 | V>L | No | 1000Genomes | |
| tmp_4_8688462_G_A,C | 47 | L>F | No | 1000Genomes | |
| ENSVATH06673116 | 56 | K>T | No | 1000Genomes | |
| tmp_4_8688500_G_A | 60 | R>K | No | 1000Genomes | |
| ENSVATH06673117 | 64 | D>H | No | 1000Genomes | |
| tmp_4_8688570_T_A | 83 | H>Q | No | 1000Genomes | |
| tmp_4_8688568_C_T | 83 | H>Y | No | 1000Genomes | |
| tmp_4_8688710_G_C | 101 | E>D | No | 1000Genomes | |
| ENSVATH06673122 | 102 | V>A | No | 1000Genomes | |
| ENSVATH06673124 | 107 | P>L | No | 1000Genomes | |
| ENSVATH06673123 | 107 | P>S | No | 1000Genomes | |
| tmp_4_8688731_G_T | 108 | K>N | No | 1000Genomes | |
| tmp_4_8688771_T_A | 122 | C>S | No | 1000Genomes | |
| ENSVATH14200521 | 142 | S>F | No | 1000Genomes | |
| tmp_4_8688917_G_C | 143 | R>T | No | 1000Genomes | |
| ENSVATH06673128 | 146 | C>Y | No | 1000Genomes | |
| ENSVATH11770907 | 158 | G>D | No | 1000Genomes | |
| ENSVATH11770908 | 160 | S>N | No | 1000Genomes | |
| ENSVATH00506807 | 176 | S>G | No | 1000Genomes | |
| tmp_4_8689123_C_G | 184 | L>V | No | 1000Genomes | |
| tmp_4_8689126_G_T | 185 | A>S | No | 1000Genomes | |
| ENSVATH00506808 | 193 | S>C | No | 1000Genomes | |
| tmp_4_8689258_A_T | 202 | Y>F | No | 1000Genomes | |
| tmp_4_8689311_A_T | 220 | S>C | No | 1000Genomes | |
| tmp_4_8689359_G_A | 236 | D>N | No | 1000Genomes | |
| ENSVATH06673133 | 238 | S>A | No | 1000Genomes | |
| ENSVATH11770913 | 239 | G>R | No | 1000Genomes | |
| tmp_4_8689372_G_C | 240 | C>S | No | 1000Genomes | |
| ENSVATH02839433 | 241 | F>Y | No | 1000Genomes | |
| ENSVATH02839434 | 245 | G>E | No | 1000Genomes | |
| tmp_4_8689397_A_T | 248 | L>F | No | 1000Genomes | |
| tmp_4_8689503_T_A | 260 | L>Q | No | 1000Genomes | |
| ENSVATH11770914 | 262 | G>R | No | 1000Genomes | |
| ENSVATH06673139 | 268 | D>N | No | 1000Genomes | |
| ENSVATH11770955 | 273 | M>T | No | 1000Genomes | |
| ENSVATH02839447 | 297 | T>N | No | 1000Genomes | |
| ENSVATH11770988 | 400 | V>I | No | 1000Genomes | |
| ENSVATH11770989 | 402 | S>I | No | 1000Genomes | |
| ENSVATH02839452 | 411 | C>Y | No | 1000Genomes | |
| ENSVATH00506809 | 413 | N>K | No | 1000Genomes | |
| ENSVATH02839453 | 418 | A>V | No | 1000Genomes | |
| ENSVATH06673154 | 428 | K>N | No | 1000Genomes | |
| tmp_4_8690400_C_T | 440 | T>I | No | 1000Genomes | |
| ENSVATH02839454 | 440 | T>P | No | 1000Genomes | |
| tmp_4_8690403_A_G | 441 | Y>C | No | 1000Genomes | |
| ENSVATH11770992 | 446 | I>M | No | 1000Genomes | |
| ENSVATH06673156 | 446 | I>T | No | 1000Genomes | |
| tmp_4_8690429_A_C | 450 | I>L | No | 1000Genomes | |
| ENSVATH06673157 | 453 | F>L | No | 1000Genomes | |
| ENSVATH11770993 | 455 | K>R | No | 1000Genomes | |
| tmp_4_8690450_G_T | 457 | D>Y | No | 1000Genomes | |
| tmp_4_8690456_G_C | 459 | G>R | No | 1000Genomes | |
| tmp_4_8690472_A_G | 464 | D>G | No | 1000Genomes | |
| ENSVATH02839455 | 466 | L>F | No | 1000Genomes | |
| ENSVATH02839456 | 467 | S>T | No | 1000Genomes | |
| ENSVATH02839457 | 467 | S>Y | No | 1000Genomes | |
| ENSVATH11771017 | 520 | F>L | No | 1000Genomes | |
| tmp_4_8690760_C_T | 534 | S>F | No | 1000Genomes | |
| tmp_4_8690768_G_A | 537 | D>N | No | 1000Genomes | |
| tmp_4_8690790_T_A | 544 | L>H | No | 1000Genomes | |
| tmp_4_8690799_C_T | 547 | S>F | No | 1000Genomes | |
| tmp_4_8690803_G_T | 548 | L>F | No | 1000Genomes | |
| tmp_4_8690927_C_G | 590 | P>A | No | 1000Genomes | |
| ENSVATH11771018 | 593 | I>N | No | 1000Genomes | |
| tmp_4_8690947_A_G | 596 | I>M | No | 1000Genomes | |
| ENSVATH02839459 | 608 | M>I | No | 1000Genomes | |
| ENSVATH14200562 | 610 | T>I | No | 1000Genomes | |
| tmp_4_8691152_G_T | 632 | A>S | No | 1000Genomes | |
| ENSVATH06673168 | 656 | T>A | No | 1000Genomes | |
| tmp_4_8691249_T_A | 664 | L>H | No | 1000Genomes | |
| tmp_4_8691248_C_A | 664 | L>I | No | 1000Genomes | |
| tmp_4_8691284_C_G | 676 | P>A | No | 1000Genomes | |
| ENSVATH14200566 | 679 | P>L | No | 1000Genomes | |
| tmp_4_8691409_T_C | 693 | Y>H | No | 1000Genomes | |
| ENSVATH11771021 | 703 | F>Y | No | 1000Genomes | |
| ENSVATH02839467 | 721 | Q>E | No | 1000Genomes | |
| ENSVATH06673172 | 725 | A>V | No | 1000Genomes | |
| ENSVATH06673173 | 730 | F>L | No | 1000Genomes | |
| tmp_4_8691608_A_G | 732 | N>D | No | 1000Genomes | |
| tmp_4_8691668_G_T | 752 | V>F | No | 1000Genomes | |
| tmp_4_8691680_G_A | 756 | A>T | No | 1000Genomes | |
| ENSVATH00506812 | 775 | N>K | No | 1000Genomes | |
| ENSVATH14200567 | 777 | Q>H | No | 1000Genomes | |
| ENSVATH02839476 | 782 | D>N | No | 1000Genomes | |
| ENSVATH11771076 | 784 | K>N | No | 1000Genomes | |
| ENSVATH11771075 | 784 | K>R | No | 1000Genomes | |
| ENSVATH11771077 | 785 | I>V | No | 1000Genomes | |
| tmp_4_8691869_T_A | 791 | N>K | No | 1000Genomes | |
| tmp_4_8691867_A_T | 791 | N>Y | No | 1000Genomes | |
| ENSVATH02839477 | 796 | E>D | No | 1000Genomes | |
| tmp_4_8691918_A_T | 808 | I>F | No | 1000Genomes | |
| tmp_4_8692061_G_A | 822 | G>D | No | 1000Genomes | |
| ENSVATH02839481 | 845 | T>N | No | 1000Genomes | |
| tmp_4_8692165_G_T | 857 | G>C | No | 1000Genomes | |
| tmp_4_8692315_A_C | 907 | T>P | No | 1000Genomes | |
| ENSVATH06673192 | 908 | S>C | No | 1000Genomes | |
| tmp_4_8692333_G_A | 913 | E>K | No | 1000Genomes | |
| ENSVATH06673193 | 916 | C>Y | No | 1000Genomes | |
| tmp_4_8692465_G_C | 930 | E>D | No | 1000Genomes | |
| ENSVATH06673195 | 931 | I>N | No | 1000Genomes | |
| ENSVATH02839484 | 938 | I>V | No | 1000Genomes | |
| ENSVATH02839485 | 986 | V>A | No | 1000Genomes | |
| tmp_4_8692710_A_G | 1012 | D>G | No | 1000Genomes | |
| ENSVATH11771127 | 1012 | D>N | No | 1000Genomes | |
| ENSVATH06673200 | 1020 | G>E | No | 1000Genomes | |
| ENSVATH11771131 | 1022 | K>N | No | 1000Genomes | |
| ENSVATH14200587 | 1023 | I>F | No | 1000Genomes | |
| ENSVATH14200588 | 1027 | G>R | No | 1000Genomes | |
| tmp_4_8692858_C_T | 1032 | H>Y | No | 1000Genomes | |
| ENSVATH11771132 | 1041 | M>K | No | 1000Genomes | |
| tmp_4_8692978_G_T | 1042 | R>S | No | 1000Genomes | |
| tmp_4_8692991_C_A | 1047 | P>T | No | 1000Genomes | |
| ENSVATH06673205 | 1064 | S>T | No | 1000Genomes | |
| ENSVATH11771134 | 1068 | E>G | No | 1000Genomes | |
| ENSVATH00506814 | 1075 | L>W | No | 1000Genomes | |
| ENSVATH06673207 | 1076 | A>G | No | 1000Genomes | |
| ENSVATH02839490 | 1077 | Q>H | No | 1000Genomes | |
| ENSVATH02839491 | 1078 | M>I | No | 1000Genomes | |
| ENSVATH02839492 | 1083 | T>I | No | 1000Genomes | |
| ENSVATH11771146 | 1093 | E>K | No | 1000Genomes | |
| ENSVATH02839496 | 1097 | C>G | No | 1000Genomes | |
| ENSVATH02839497 | 1115 | S>G | No | 1000Genomes | |
| ENSVATH02839498 | 1115 | S>T | No | 1000Genomes | |
| tmp_4_8693336_C_A | 1138 | L>I | No | 1000Genomes | |
| tmp_4_8693356_G_A | 1144 | M>I | No | 1000Genomes | |
| tmp_4_8693358_C_G | 1145 | S>C | No | 1000Genomes | |
| tmp_4_8693391_G_T | 1156 | W>L | No | 1000Genomes | |
| tmp_4_8693397_A_G | 1158 | K>R | No | 1000Genomes | |
| ENSVATH02839503 | 1191 | L>I | No | 1000Genomes | |
| ENSVATH00506815 | 1193 | S>C | No | 1000Genomes | |
| ENSVATH14200590 | 1200 | V>I | No | 1000Genomes | |
| ENSVATH11771151 | 1208 | R>L | No | 1000Genomes | |
| ENSVATH06673221 | 1216 | S>T | No | 1000Genomes | |
| tmp_4_8693679_T_C | 1217 | L>P | No | 1000Genomes | |
| tmp_4_8693788_G_T | 1221 | L>F | No | 1000Genomes | |
| ENSVATH11771196 | 1233 | V>I | No | 1000Genomes | |
| tmp_4_8693826_A_C | 1234 | Y>S | No | 1000Genomes | |
| tmp_4_8693858_C_A | 1245 | H>N | No | 1000Genomes | |
| ENSVATH02839512 | 1249 | F>Y | No | 1000Genomes | |
| ENSVATH14200591 | 1274 | V>M | No | 1000Genomes | |
| ENSVATH02839513 | 1281 | I>V | No | 1000Genomes | |
| ENSVATH02839515 | 1291 | A>S | No | 1000Genomes | |
| tmp_4_8694202_A_T | 1317 | S>C | No | 1000Genomes | |
| ENSVATH11771199 | 1323 | L>F | No | 1000Genomes | |
| tmp_4_8694223_A_T | 1324 | N>Y | No | 1000Genomes | |
| tmp_4_8694271_G_T | 1340 | A>S | No | 1000Genomes | |
| tmp_4_8694299_A_C | 1349 | D>A | No | 1000Genomes | |
| tmp_4_8694303_C_A | 1350 | F>L | No | 1000Genomes | |
| ENSVATH06673231 | 1353 | D>N | No | 1000Genomes | |
| tmp_4_8694328_T_G | 1359 | Y>D | No | 1000Genomes | |
| ENSVATH00506816 | 1380 | F>L | No | 1000Genomes | |
| ENSVATH06673234 | 1388 | N>K | No | 1000Genomes | |
| ENSVATH14200638 | 1391 | K>Q | No | 1000Genomes |
No associated diseases with Q7PC82
9 regional properties for Q7PC82
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 139 - 413 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 800 - 1045 | IPR003439-2 |
| domain | AAA+ ATPase domain | 165 - 390 | IPR003593-1 |
| domain | AAA+ ATPase domain | 829 - 1021 | IPR003593-2 |
| domain | ABC-2 type transporter, transmembrane domain | 493 - 703 | IPR013525-1 |
| domain | ABC-2 type transporter, transmembrane domain | 1117 - 1330 | IPR013525-2 |
| domain | Plant PDR ABC transporter associated | 708 - 770 | IPR013581 |
| domain | ATP-binding cassette transporter, PDR-like subfamily G, domain 2 | 797 - 1027 | IPR034003 |
| domain | ABC transporter family G domain | 1001 - 1063 | IPR043926 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08409 | AUS1 | ATP-dependent permease AUS1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P40550 | PDR11 | ATP-dependent permease PDR11 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q8GU92 | ABCG35 | ABC transporter G family member 35 | Oryza sativa subsp japonica (Rice) | PR |
| Q8GU83 | ABCG41 | ABC transporter G family member 41 | Oryza sativa subsp japonica (Rice) | PR |
| O81016 | ABCG32 | ABC transporter G family member 32 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC81 | ABCG43 | ABC transporter G family member 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC83 | ABCG41 | ABC transporter G family member 41 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LFH0 | ABCG37 | ABC transporter G family member 37 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZUT8 | ABCG33 | ABC transporter G family member 33 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GZ52 | ABCG30 | ABC transporter G family member 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTMSQTDGVE | FASRNTNENG | HDDDDQLRSQ | WVAIERSPTF | ERITTALFCK | RDEKGKKSQR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RVMDVSKLDD | LDRRLFIDDL | IRHVENDNHV | LLQKIRKRID | EVGIDLPKIE | ARFSDLFVEA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ECEVVYGKPI | PTLWNAISSK | LSRFMCSNQA | KKISILKGVS | GIIRPKRMTL | LLGPPSCGKT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TLLLALSGRL | DPSLKTRGDI | SYNGHLFSEF | VPEKTSSYVS | QNDLHIPELS | VRETLDFSGC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FQGTGSRLEM | TKEISRREKL | KGIVPDPDID | AYMKAASIEG | SKTNLQTDYI | LKILGLTICA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DTRVGDASRP | GISGGQKRRL | TTGEMIVGPI | KTLFMDEISN | GLDSSTTFQI | LSCLQQFARL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SEGTILVSLL | QPAPETFELF | DDLILMGEGK | IIYHGPRDFV | CSFFEDCGFK | CPNRKSVAEF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LQEVISRKDQ | EQYWCHIEKT | YCYVSIESFI | EKFKKSDLGL | ELQDRLSKTY | DKSQTQKDGL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| CFRKYSLSNW | DMLKACSRRE | FLLMKRNSFV | YVFKSGLLIF | IGFIAMTVYL | RTGSTRDSLH |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ANYLMGSLFF | SLFKLLADGL | PELTLTISRI | AVFCKQKELY | FYPAWAYAIP | SAILKIPISF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LESFLWTMLT | YYVIGYSPEM | GRFIRQFLIL | FALHLSCISM | FRAIAAVFRD | FVVATTVGSI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| SIVLLSVFGG | FIVRKPSMPS | WLEWGFWLSP | LSYAEIGLTA | NEFFAPRWGK | ITSENRTLGE |
| 730 | 740 | 750 | 760 | 770 | 780 |
| QVLDARGLNF | GNQSYWNAFG | ALIGFTLFFN | TVFALALTFL | KTSQRSRVIV | SHEKNTQSSE |
| 790 | 800 | 810 | 820 | 830 | 840 |
| NDSKIASRFK | NALPFEPLTF | TFQDVQYIIE | TPQGKKLQLL | SGVTGAFKPG | VLTALMGVSG |
| 850 | 860 | 870 | 880 | 890 | 900 |
| AGKTTLLDVL | SGRKTFGDIK | GQIEVGGYVK | VQDTFSRVSG | YCEQFDIHSP | NLTVQESLKY |
| 910 | 920 | 930 | 940 | 950 | 960 |
| SAWLRLTSNI | SSETKCAIVN | EVLETIELEE | IKDSIVGIPG | ISGLTTEQRK | RLTIAVELVS |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| NPSIIFMDEP | TTGLDARAAA | IVMRAVKNIA | ETGRTVVCTI | HQPSIDIFEA | FDELILMKNG |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| GKIIYYGPLG | QHSSKVIEYF | MRIHGVPKLK | ENSNPATWIL | DITSKSSEDK | LGVDLAQMYE |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| ESTLFKENKM | VIEQTRCTSL | GSERLILSSR | YAQTSWEQFK | ACLWKQHLSY | WRNPSYNLTR |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| IIFMSFTCML | CGILFWQKAK | EINNQQDLFN | VFGSMFTVVL | FSGINNCSTV | LFSVATERNV |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| FYRERFSRMY | NSWAYSLAQV | LVEIPYSLFQ | SIVYVIIVYP | MVGYHWSVFK | VFWSFYSIFC |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| TLLIFNYFGM | LLVVVTPNVH | IAFTLRSSFY | AIVNLFAGYV | MPKPNIPRWW | IWMYYLSPTS |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| WVLNGLLTSQ | YGDMEKEILA | FGEKKKVSDF | LEDYFGYRYD | SLALVAVVLI | AFPILLASLF |
| 1390 | |||||
| AFFIGKLNFQ | KK |